Content
| Max Planck Institute for Molecular Genetics |
|
Deutsche Krebshilfe |
|
-
Jaeger et al.
Gene expression signatures in melanoma tissues
No.
of sample
|
Tumor
no.
in
text
|
Melanoma
subtype
|
Vertical
tumor
thickness (mm)
of
whole tumor
|
Vertical
tumor
thickness (mm)
of
biopsy
|
Clark
level
|
Clinical
stage*)
|
1.
|
NM1
|
NMM
|
2.90
|
2.55
|
L IV
|
IIA
|
2.
|
NM2
|
NMM
|
11.00
|
9.30
|
LV
|
IIC
|
3.
|
NM3
|
NMM
|
4.20
|
4.10
|
LIV
|
IIB
|
4.
|
NM4
|
NMM
|
6.00
|
5.73
|
LIV
|
IIB
|
5.
|
NM5
|
NMM
|
4.80
|
4.77
|
LIV
|
IIB
|
6.
|
SSM1
|
SSM
|
0.45
|
0.42
|
LII
|
IA
|
7.
|
SSM2
|
SSM
|
0.38
|
0.35
|
LIII
|
IA
|
8.
|
SSM3
|
SSM
|
0.80
|
0.72
|
LIII
|
IA
|
9.
|
SSM4
|
SSM
|
0.93
|
0.75
|
LIII
|
IA
|
10.
|
SSM5
|
SSM
|
0.77
|
0.72
|
LIII
|
IA
|
11.
|
SSM6
|
SSM
|
5.67
|
5.40
|
LV
|
IIB
|
12.
|
SSM7
|
SSM
|
0.60
|
0.60
|
LIII
|
IA
|
13.
|
SSM8
|
SSM
|
in
situ
|
in situ
|
Ø
|
0
|
14.
|
SSM9
|
SSM
|
0.95
|
0.90
|
LIV
|
IA
|
14.
|
SSM10
|
SSM
|
1.50
|
1.50
|
LIII
|
IB
|
16.
|
SSM11
|
SSM
|
0.88
|
0.85
|
LIII
|
IA
|
17.
|
SSM12
|
SSM
|
0.41
|
0.41
|
LIII
|
IA
|
18.
|
SSM13
|
SSM
|
5.40
|
5.10
|
LIV
|
IIB
|
19.
|
ALM1
|
ALM
|
2.50
|
2.32
|
LIV
|
IIA
|
Supplementary Table
1 List of melanoma samples from primary melanomas analysed in the presented
study. Nineteen tissue biopsies of different melanoma subtypes from 19
different patients were used for laser-capture micodissection of melanoma cells
and DNA microarray analyses. Vertical tumor thicknesses of whole tumors reached
from 0.38-11.00 mm, including one in situ melanoma. Vertical tumor thicknesses
of biospies reached from 0.35-9.30 mm, including one in situ melanoma. *) Classification
of clinical stage was done according to Balch CM, Buzaid AC, Atkins MB,
Cascinelli N, Coit DG, Fleming ID, Houghton Jr. A, Kirkwood JM, Mihm MF, Morton
DL, Reintgen D, Ross MI, Sober A, Soong SJ, Thompson JA, Thompson JF, Gershenwald
JE, McMasters KM. 2000. A new American Joint Committee on Cancer staging system
for cutaneous melanoma. Cancer 88:1484-1491
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