Courses in Practical DNA Microarray Analysis 2003
October 07 - 10 in Heidelberg
This course is already over!
Datasets and additional packages used in the practical sessions can be found here, links to the tutorial slides and assignments in the table below.
| Tuesday, October 07 | ||
| 09.00-10.30 | First analysis steps | Wolfgang Huber |
| 11.00-12.30 | Differential gene expression | Anja von Heydebreck |
| 13.30-14.30 | First steps in R | Florian Markowetz |
| 14.45-17.00 | Exercises: Exploring cDNA data | Wolfgang Huber |
| Wednesday, October 08 | ||
| 09.00-10.30 | Exploratory data analysis | Jörg Rahnenführer |
| 10.30-11.30 | Resampling and the bootstrap | Axel Benner |
| 11.30-12.00 | Screening by ROC curve analysis | Axel Benner |
| 13.30-14.30 | BioConductor | Wolfgang Huber |
| 14.45-17.00 | Exercises: 2x2 factorial design | Wolfgang Huber |
| Thursday, October 09 | ||
| 09.00-10.30 | Molecular Diagnosis | Rainer Spang |
| 10.30-11.30 | Classification by Support Vector Machines | Florian Markowetz |
| 11.30-12.30 | Model Assessment and Selection | Axel Benner |
| 13.30-17.00 | Exercises: classification, model selection | Florian Markowetz Axel Benner |
| Friday, October 10 | ||
| 09.00-11.00 | Design of microarray experiments | Ulrich Mansmann |
| 11.00-12.30 | Annotation | Benedikt Brors |
| 13.30-17.00 | Exercises: Bootstrap | Ulrich Mansmann |
How to find us
We will meet on the science campus of the university of Heidelberg, "Im Neuenheimer Feld", building no. 305, room 144 (that is the seminar room in the 1st floor) on Tuesday Oct 07 at 9 am.
Here are some links that may be helpful in finding the Neuenheimer Feld in Heidelberg:
http://www.uni-heidelberg.de/univ/besucher/anfahrt.html
http://med.uni-hd.de/karte/index.html
And here is a map that should help you in finding building 305 - it is marked with a circle:
http://www.uni-heidelberg.de/univ/besucher/karten/6305.html
Bring your own data
You are encouraged to bring some of your own data to the course (e.g. genepix files or CEL/CDF). We will use this during the exercises. If you expect to have own data only later in the year, it may in fact be advantageous also to register for one the later courses in Berlin or Heidelberg.
Background Knowledge
Ideally, you are interested in mathematical and statistical problems and are familiar with at least one programming language. This course focusses on the practical side of gene expression data analysis. However, data analysis without understanding the statistical background is in general impossible. We strongly recommend you to refresh your mathematical and programming skills before attending the course.
R and Bioconductor
In the afternoon exercises you will learn how to analyze data using the statistical computing environment R [http://www.r-project.org] and BioConductor [http://www.bioconductor.org], a open source software for bioinformatics. R sources and package sources can be downloaded from The Comprehensive R Archive Network at http://cran.r-project.org. Basics are explained in Introduction to R.
Participants
| • | Jochen Hess | DKFZ Heidelberg: Signal Transduction and Growth Control | |
| • | Sabine Gack | DKFZ Heidelberg: Signal Transduction and Growth Control | |
| • | Oliver Pein | DKFZ Heidelberg: Signal Transduction and Growth Control | |
| • | Bernhard Winkelmann | Uniklinikum Heidelberg | |
| • | Anja Victor | ||
| • | Jo Vandesompele | Center for medical genetics, Ghent, Belgium | |
| • | Bettina Kulle | Department of Genetic Epidemiology, University of Göttingen | |
| • | Alexander Schramm | Uniklinikum Essen | |
| • | Giovanni Malerba | University of Verona, Italy | |
| • | Cristina Patuzzo | University of Verona, Italy | |
| • | Dirk Repsilber | Institut für medizinische Biometrie und Statistik, Universität Lübeck | |
| • | Rohit Ghai | Uniklinikum Giessen | |
| • | Till Soerensen | ||
| • | Suse Beyer | Merck Darmstadt | |
| • | Michaela Kröger | Merck Darmstadt | |
| • | Christa Wiederkehr | Swiss Institute of Bioinformatics, Basel | |
| • | Johannes Schulte |
Thank you for registering! This course is fully booked and closed for registration. If you will not be able to attend, please contact Wolfgang Huber as soon as possible so that we can notify the people on the waiting list.
Further information
Please contact Dr. Wolfgang Huber: w.huber@dkfz.de