GO:0007242

GO:0007242

intracellular signaling cascade

Biological Process

Parent node

GO:0007165	signal transduction

8 child nodes

ID	Term	Weight
GO:0001508	regulation of action potential	0.00000
GO:0009755	hormone mediated signaling	0.00000
GO:0030522	intracellular receptor-mediated signaling pathway	0.00000
GO:0007263	nitric oxide mediated signal transduction	0.00000
GO:0007243	protein kinase cascade	0.00000
GO:0019932	second-messenger-mediated signaling	0.00000
GO:0007264	small GTPase mediated signal transduction	0.13938
GO:0007242a	intracellular signaling cascade (annotated genes)	0.8606169

Performance on training data

• Error rate: 0
• Performance: 0.02748
• Redundancy: 5.35166

	Sensitivity	Specificity
T-ALL	1	1
other	1	1

Performance on test data

• Error rate: 0.02752
• Performance: 0.2784
• Redundancy: 5.34814

	Sensitivity	Specificity
T-ALL	0.85714	0.98947
other	0.98947	0.85714

Predictions

	Class	T-ALL	other	Predictionn
BCR-ABL-1	other	0.00013	0.99987	other
BCR-ABL-2	other	0.00269	0.99731	other
BCR-ABL-3 (testset)	other	0.00024	0.99976	other
BCR-ABL-4	other	0.00087	0.99913	other
BCR-ABL-5	other	0.00036	0.99964	other
BCR-ABL-6 (testset)	other	0.00016	0.99984	other
BCR-ABL-7 (testset)	other	0.008	0.992	other
BCR-ABL-8 (testset)	other	0.00036	0.99964	other
BCR-ABL-9 (testset)	other	0.00027	0.99973	other
BCR-ABL-C1 (testset)	other	0.0011	0.9989	other
BCR-ABL-Hyperdip-10 (testset)	other	0.00031	0.99969	other
BCR-ABL-Hyperdip-R5	other	0.00058	0.99942	other
BCR-ABL-R1	other	0.00119	0.99881	other
BCR-ABL-R2	other	0.00054	0.99946	other
BCR-ABL-R3 (testset)	other	0.00173	0.99827	other
E2A-PBX1-10	other	0.00126	0.99874	other
E2A-PBX1-11	other	0.00079	0.99921	other
E2A-PBX1-12 (testset)	other	3e-04	0.9997	other
E2A-PBX1-13	other	0.01434	0.98566	other
E2A-PBX1-1	other	0.00112	0.99888	other
E2A-PBX1-2	other	0.00231	0.99769	other
E2A-PBX1-3	other	0.00135	0.99865	other
E2A-PBX1-4 (testset)	other	0.00092	0.99908	other
E2A-PBX1-5	other	0.00222	0.99778	other
E2A-PBX1-6	other	5e-04	0.9995	other
E2A-PBX1-7	other	0.00145	0.99855	other
E2A-PBX1-8	other	0.0076	0.9924	other
E2A-PBX1-9	other	0.03696	0.96304	other
E2A-PBX1-2M1	other	0.00055	0.99945	other
E2A-PBX1-C10	other	0.01164	0.98836	other
E2A-PBX1-C11	other	0.00079	0.99921	other
E2A-PBX1-C12	other	0.00563	0.99437	other
E2A-PBX1-C1	other	0.00751	0.99249	other
E2A-PBX1-C2	other	0.00697	0.99303	other
E2A-PBX1-C3 (testset)	other	0.00045	0.99955	other
E2A-PBX1-C4	other	0.00108	0.99892	other
E2A-PBX1-C5 (testset)	other	0.00041	0.99959	other
E2A-PBX1-C6	other	0.00019	0.99981	other
E2A-PBX1-C7	other	0.00143	0.99857	other
E2A-PBX1-C8	other	0.06056	0.93944	other
E2A-PBX1-C9	other	0.00157	0.99843	other
E2A-PBX1-R1	other	0.00036	0.99964	other
Hyperdip-50-10	other	0.00205	0.99795	other
Hyperdip-50-11 (testset)	other	0.07344	0.92656	other
Hyperdip-50-12	other	0.00098	0.99902	other
Hyperdip-50-13 (testset)	other	0.00105	0.99895	other
Hyperdip-50-14	other	0.00093	0.99907	other
Hyperdip-50-1	other	0.00038	0.99962	other
Hyperdip-50-2	other	0.00196	0.99804	other
Hyperdip-50-3 (testset)	other	0.00018	0.99982	other
Hyperdip-50-4 (testset)	other	0.20835	0.79165	other
Hyperdip-50-5 (testset)	other	0.00019	0.99981	other
Hyperdip-50-6	other	0.00096	0.99904	other
Hyperdip-50-7	other	9e-05	0.99991	other
Hyperdip-50-8 (testset)	other	0.00015	0.99985	other
Hyperdip-50-9	other	0.00019	0.99981	other
Hyperdip-50-2M1	other	0.00068	0.99932	other
Hyperdip-50-2M2 (testset)	other	5e-05	0.99995	other
Hyperdip-50-C10	other	0.00223	0.99777	other
Hyperdip-50-C11 (testset)	other	0.00056	0.99944	other
Hyperdip-50-C12	other	0.00028	0.99972	other
Hyperdip-50-C13	other	0.00075	0.99925	other
Hyperdip-50-C14	other	0.00148	0.99852	other
Hyperdip-50-C15	other	0.00045	0.99955	other
Hyperdip-50-C16	other	0.00015	0.99985	other
Hyperdip-50-C17	other	0.00224	0.99776	other
Hyperdip-50-C18	other	0.00068	0.99932	other
Hyperdip-50-C19 (testset)	other	0.00018	0.99982	other
Hyperdip-50-C1	other	0.00066	0.99934	other
Hyperdip-50-C20	other	0.00118	0.99882	other
Hyperdip-50-C21	other	0.00021	0.99979	other
Hyperdip-50-C22 (testset)	other	0.00021	0.99979	other
Hyperdip-50-C23	other	0.00017	0.99983	other
Hyperdip-50-C24	other	0.00056	0.99944	other
Hyperdip-50-C25	other	0.00174	0.99826	other
Hyperdip-50-C26	other	5e-04	0.9995	other
Hyperdip-50-C27-N	other	0.00026	0.99974	other
Hyperdip-50-C28	other	0.00021	0.99979	other
Hyperdip-50-C29 (testset)	other	0.00027	0.99973	other
Hyperdip-50-C2 (testset)	other	0.01378	0.98622	other
Hyperdip-50-C30	other	0.00044	0.99956	other
Hyperdip-50-C31	other	0.00027	0.99973	other
Hyperdip-50-C32	other	8e-05	0.99992	other
Hyperdip-50-C33	other	0.00026	0.99974	other
Hyperdip-50-C34	other	0.00038	0.99962	other
Hyperdip-50-C35 (testset)	other	0.00107	0.99893	other
Hyperdip-50-C36	other	0.00062	0.99938	other
Hyperdip-50-C37	other	0.00036	0.99964	other
Hyperdip-50-C38	other	0.00145	0.99855	other
Hyperdip-50-C39 (testset)	other	0.00064	0.99936	other
Hyperdip-50-C3	other	0.00016	0.99984	other
Hyperdip-50-C40	other	0.00027	0.99973	other
Hyperdip-50-C41 (testset)	other	0.00108	0.99892	other
Hyperdip-50-C42 (testset)	other	0.00455	0.99545	other
Hyperdip-50-C43	other	0.00057	0.99943	other
Hyperdip-50-C4	other	3e-04	0.9997	other
Hyperdip-50-C5 (testset)	other	0.01879	0.98121	other
Hyperdip-50-C6	other	0.00047	0.99953	other
Hyperdip-50-C7 (testset)	other	0.00014	0.99986	other
Hyperdip-50-C8 (testset)	other	0.00012	0.99988	other
Hyperdip-50-C9	other	0.00015	0.99985	other
Hyperdip-50-R1	other	0.0013	0.9987	other
Hyperdip-50-R2 (testset)	other	0.00019	0.99981	other
Hyperdip-50-R3	other	1e-04	0.9999	other
Hyperdip-50-R4	other	0.00055	0.99945	other
Hyperdip-50-R5 (testset)	other	0.00032	0.99968	other
Hyperdip47-50-1	other	0.00131	0.99869	other
Hyperdip47-50-2	other	0.00252	0.99748	other
Hyperdip47-50-3 (testset)	other	0.857	0.143	T-ALL
Hyperdip47-50-2M1 (testset)	other	0.00043	0.99957	other
Hyperdip47-50-C10 (testset)	other	0.00459	0.99541	other
Hyperdip47-50-C11	other	8e-04	0.9992	other
Hyperdip47-50-C12	other	0.02652	0.97348	other
Hyperdip47-50-C13	other	0.00299	0.99701	other
Hyperdip47-50-C14-N (testset)	other	0.00025	0.99975	other
Hyperdip47-50-C15 (testset)	other	0.00036	0.99964	other
Hyperdip47-50-C16	other	6e-05	0.99994	other
Hyperdip47-50-C17	other	0.00111	0.99889	other
Hyperdip47-50-C18	other	0.00045	0.99955	other
Hyperdip47-50-C19	other	0.00903	0.99097	other
Hyperdip47-50-C1 (testset)	other	0.00016	0.99984	other
Hyperdip47-50-C2 (testset)	other	0.00504	0.99496	other
Hyperdip47-50-C3-N (testset)	other	0.00017	0.99983	other
Hyperdip47-50-C4	other	0.00046	0.99954	other
Hyperdip47-50-C5 (testset)	other	0.15185	0.84815	other
Hyperdip47-50-C6 (testset)	other	0.00679	0.99321	other
Hyperdip47-50-C7	other	1e-04	0.9999	other
Hyperdip47-50-C8	other	0.00039	0.99961	other
Hyperdip47-50-C9	other	0.00035	0.99965	other
Hypodip-1 (testset)	other	0.00746	0.99254	other
Hypodip-2	other	0.06713	0.93287	other
Hypodip-2M1 (testset)	other	0.01351	0.98649	other
Hypodip-C1	other	0.00296	0.99704	other
Hypodip-C2 (testset)	other	0.00017	0.99983	other
Hypodip-C3	other	0.00094	0.99906	other
Hypodip-C4	other	0.00011	0.99989	other
Hypodip-C5	other	0.00098	0.99902	other
Hypodip-C6 (testset)	other	0.00022	0.99978	other
MLL-1 (testset)	other	0.00028	0.99972	other
MLL-2	other	8e-05	0.99992	other
MLL-3 (testset)	other	0.00044	0.99956	other
MLL-4	other	0.00021	0.99979	other
MLL-5 (testset)	other	6e-05	0.99994	other
MLL-6 (testset)	other	9e-05	0.99991	other
MLL-7	other	9e-05	0.99991	other
MLL-8 (testset)	other	0.00015	0.99985	other
MLL-2M1	other	0.00036	0.99964	other
MLL-2M2 (testset)	other	0.00011	0.99989	other
MLL-C1	other	4e-05	0.99996	other
MLL-C2	other	0.00021	0.99979	other
MLL-C3 (testset)	other	0.16206	0.83794	other
MLL-C4	other	0.00018	0.99982	other
MLL-C5	other	0.07957	0.92043	other
MLL-C6	other	0.00489	0.99511	other
MLL-R1 (testset)	other	0.00014	0.99986	other
MLL-R2	other	1e-04	0.9999	other
MLL-R3	other	0.00016	0.99984	other
MLL-R4	other	0.00014	0.99986	other
Normal-1	other	0.00029	0.99971	other
Normal-2	other	0.00015	0.99985	other
Normal-3	other	7e-04	0.9993	other
Normal-C1-N	other	0.00158	0.99842	other
Normal-C10	other	0.00038	0.99962	other
Normal-C11-N (testset)	other	0.00025	0.99975	other
Normal-C12 (testset)	other	0.00022	0.99978	other
Normal-C2-N	other	3e-04	0.9997	other
Normal-C3-N	other	0.00019	0.99981	other
Normal-C4-N	other	0.00017	0.99983	other
Normal-C5	other	0.00064	0.99936	other
Normal-C6 (testset)	other	7e-04	0.9993	other
Normal-C7-N (testset)	other	0.00042	0.99958	other
Normal-C8	other	0.00143	0.99857	other
Normal-C9 (testset)	other	0.00242	0.99758	other
Normal-R1 (testset)	other	0.00121	0.99879	other
Normal-R2-N	other	0.00079	0.99921	other
Normal-R3	other	4e-04	0.9996	other
Pseudodip-1	other	0.00127	0.99873	other
Pseudodip-2	other	0.12221	0.87779	other
Pseudodip-3	other	0.00179	0.99821	other
Pseudodip-4 (testset)	other	0.00312	0.99688	other
Pseudodip-5 (testset)	other	0.00017	0.99983	other
Pseudodip-6 (testset)	other	1e-04	0.9999	other
Pseudodip-7	other	0.00151	0.99849	other
Pseudodip-8-N	other	0.00048	0.99952	other
Pseudodip-9	other	0.00446	0.99554	other
Pseudodip-C10 (testset)	other	0.0109	0.9891	other
Pseudodip-C11 (testset)	other	0.0017	0.9983	other
Pseudodip-C12 (testset)	other	0.01104	0.98896	other
Pseudodip-C13	other	0.00132	0.99868	other
Pseudodip-C14 (testset)	other	0.00086	0.99914	other
Pseudodip-C15	other	0.00025	0.99975	other
Pseudodip-C16-N (testset)	other	0.00319	0.99681	other
Pseudodip-C17	other	0.00231	0.99769	other
Pseudodip-C18	other	5e-05	0.99995	other
Pseudodip-C19	other	0.00016	0.99984	other
Pseudodip-C1	other	0.00098	0.99902	other
Pseudodip-C2-N	other	0.00036	0.99964	other
Pseudodip-C3	other	0.00038	0.99962	other
Pseudodip-C4	other	0.00017	0.99983	other
Pseudodip-C5 (testset)	other	0.00055	0.99945	other
Pseudodip-C6	other	0.00234	0.99766	other
Pseudodip-C7	other	0.00091	0.99909	other
Pseudodip-C8	other	3e-04	0.9997	other
Pseudodip-C9	other	0.00112	0.99888	other
Pseudodip-R1-N (testset)	other	9e-05	0.99991	other
T-ALL-10 (testset)	T-ALL	0.99999	1e-05	T-ALL
T-ALL-1 (testset)	T-ALL	0.99987	0.00013	T-ALL
T-ALL-2 (testset)	T-ALL	0.00801	0.99199	other
T-ALL-3	T-ALL	1	0	T-ALL
T-ALL-4 (testset)	T-ALL	0.99996	4e-05	T-ALL
T-ALL-5 (testset)	T-ALL	0.99998	2e-05	T-ALL
T-ALL-6	T-ALL	0.99999	1e-05	T-ALL
T-ALL-7 (testset)	T-ALL	0.99973	0.00027	T-ALL
T-ALL-8 (testset)	T-ALL	0.99999	1e-05	T-ALL
T-ALL-9	T-ALL	0.9998	2e-04	T-ALL
T-ALL-2M1	T-ALL	0.99999	1e-05	T-ALL
T-ALL-C10	T-ALL	1	0	T-ALL
T-ALL-C11	T-ALL	0.99982	0.00018	T-ALL
T-ALL-C12	T-ALL	0.99999	1e-05	T-ALL
T-ALL-C13	T-ALL	0.99999	1e-05	T-ALL
T-ALL-C14	T-ALL	0.96608	0.03392	T-ALL
T-ALL-C15 (testset)	T-ALL	1	0	T-ALL
T-ALL-C16 (testset)	T-ALL	0.93039	0.06961	T-ALL
T-ALL-C17	T-ALL	0.58305	0.41695	T-ALL
T-ALL-C18	T-ALL	0.90914	0.09086	T-ALL
T-ALL-C19	T-ALL	0.98006	0.01994	T-ALL
T-ALL-C1	T-ALL	0.86441	0.13559	T-ALL
T-ALL-C20	T-ALL	0.99981	0.00019	T-ALL
T-ALL-C21	T-ALL	0.99958	0.00042	T-ALL
T-ALL-C22 (testset)	T-ALL	1	0	T-ALL
T-ALL-C23	T-ALL	0.75775	0.24225	T-ALL
T-ALL-C24 (testset)	T-ALL	0.99997	3e-05	T-ALL
T-ALL-C25 (testset)	T-ALL	0.99963	0.00037	T-ALL
T-ALL-C26	T-ALL	0.99956	0.00044	T-ALL
T-ALL-C2	T-ALL	0.99998	2e-05	T-ALL
T-ALL-C3	T-ALL	1	0	T-ALL
T-ALL-C4	T-ALL	0.99754	0.00246	T-ALL
T-ALL-C5 (testset)	T-ALL	0.00108	0.99892	other
T-ALL-C6	T-ALL	0.99991	9e-05	T-ALL
T-ALL-C7 (testset)	T-ALL	0.99986	0.00014	T-ALL
T-ALL-C8	T-ALL	0.97855	0.02145	T-ALL
T-ALL-C9	T-ALL	0.99998	2e-05	T-ALL
T-ALL-R1	T-ALL	0.9962	0.0038	T-ALL
T-ALL-R2	T-ALL	0.99984	0.00016	T-ALL
T-ALL-R3	T-ALL	0.99998	2e-05	T-ALL
T-ALL-R4	T-ALL	0.99999	1e-05	T-ALL
T-ALL-R5	T-ALL	0.93305	0.06695	T-ALL
T-ALL-R6	T-ALL	0.92691	0.07309	T-ALL
TEL-AML1-10	other	0.00164	0.99836	other
TEL-AML1-11 (testset)	other	2e-04	0.9998	other
TEL-AML1-12	other	0.0132	0.9868	other
TEL-AML1-13 (testset)	other	0.00143	0.99857	other
TEL-AML1-14	other	0.00047	0.99953	other
TEL-AML1-1	other	0.00057	0.99943	other
TEL-AML1-2	other	0.00295	0.99705	other
TEL-AML1-3	other	0.01967	0.98033	other
TEL-AML1-4	other	0.00031	0.99969	other
TEL-AML1-5 (testset)	other	0.00053	0.99947	other
TEL-AML1-6	other	0.00052	0.99948	other
TEL-AML1-7	other	0.00123	0.99877	other
TEL-AML1-8 (testset)	other	0.001	0.999	other
TEL-AML1-9	other	0.00297	0.99703	other
TEL-AML1-2M1 (testset)	other	0.0038	0.9962	other
TEL-AML1-2M2	other	0.00103	0.99897	other
TEL-AML1-2M3	other	0.00021	0.99979	other
TEL-AML1-2M4 (testset)	other	0.00346	0.99654	other
TEL-AML1-2M5	other	0.00068	0.99932	other
TEL-AML1-C10	other	0.00133	0.99867	other
TEL-AML1-C11	other	0.00139	0.99861	other
TEL-AML1-C12	other	0.00022	0.99978	other
TEL-AML1-C13	other	0.00049	0.99951	other
TEL-AML1-C14 (testset)	other	0.00046	0.99954	other
TEL-AML1-C15	other	0.00133	0.99867	other
TEL-AML1-C16	other	0.00052	0.99948	other
TEL-AML1-C17	other	0.00075	0.99925	other
TEL-AML1-C18	other	0.00061	0.99939	other
TEL-AML1-C19 (testset)	other	0.00058	0.99942	other
TEL-AML1-C1 (testset)	other	0.00124	0.99876	other
TEL-AML1-C20 (testset)	other	0.00098	0.99902	other
TEL-AML1-C21	other	0.00125	0.99875	other
TEL-AML1-C22	other	0.14833	0.85167	other
TEL-AML1-C23 (testset)	other	0.00019	0.99981	other
TEL-AML1-C24	other	0.00163	0.99837	other
TEL-AML1-C25	other	0.00352	0.99648	other
TEL-AML1-C26 (testset)	other	0.00339	0.99661	other
TEL-AML1-C27	other	0.00044	0.99956	other
TEL-AML1-C28 (testset)	other	0.00158	0.99842	other
TEL-AML1-C29	other	0.00065	0.99935	other
TEL-AML1-C2	other	0.00407	0.99593	other
TEL-AML1-C30	other	0.00372	0.99628	other
TEL-AML1-C31 (testset)	other	0.00143	0.99857	other
TEL-AML1-C32	other	0.0328	0.9672	other
TEL-AML1-C33 (testset)	other	0.00038	0.99962	other
TEL-AML1-C34	other	0.00025	0.99975	other
TEL-AML1-C35	other	0.00075	0.99925	other
TEL-AML1-C36 (testset)	other	0.00089	0.99911	other
TEL-AML1-C37	other	0.00071	0.99929	other
TEL-AML1-C38	other	0.00018	0.99982	other
TEL-AML1-C39	other	0.00041	0.99959	other
TEL-AML1-C3	other	0.0027	0.9973	other
TEL-AML1-C40	other	0.00022	0.99978	other
TEL-AML1-C41	other	0.00218	0.99782	other
TEL-AML1-C42	other	0.00412	0.99588	other
TEL-AML1-C43	other	0.00016	0.99984	other
TEL-AML1-C44	other	0.00102	0.99898	other
TEL-AML1-C45	other	2e-04	0.9998	other
TEL-AML1-C46	other	0.06266	0.93734	other
TEL-AML1-C47	other	0.00042	0.99958	other
TEL-AML1-C48	other	0.36437	0.63563	other
TEL-AML1-C49 (testset)	other	0.00028	0.99972	other
TEL-AML1-C4 (testset)	other	0.00338	0.99662	other
TEL-AML1-C50	other	0.00039	0.99961	other
TEL-AML1-C51 (testset)	other	0.00039	0.99961	other
TEL-AML1-C52	other	0.00678	0.99322	other
TEL-AML1-C53 (testset)	other	0.24132	0.75868	other
TEL-AML1-C54	other	0.00057	0.99943	other
TEL-AML1-C55 (testset)	other	0.00127	0.99873	other
TEL-AML1-C56	other	0.00265	0.99735	other
TEL-AML1-C57	other	0.00331	0.99669	other
TEL-AML1-C5 (testset)	other	0.00319	0.99681	other
TEL-AML1-C6	other	0.00104	0.99896	other
TEL-AML1-C7	other	0.00736	0.99264	other
TEL-AML1-C8	other	0.00077	0.99923	other
TEL-AML1-C9	other	0.00377	0.99623	other
TEL-AML1-R1 (testset)	other	0.0011	0.9989	other
TEL-AML1-R2 (testset)	other	0.00227	0.99773	other
TEL-AML1-R3	other	0.00025	0.99975	other