GO:0007242


GO:0007242

intracellular signaling cascade
(annotated genes)

Biological
Process

Parent node

This leaf node contains 312 genes

The following 312 of these are used in classification:

 SymbolGenenameE2A-PBX1 scoreother score
362_atPRKCZ protein kinase C, zeta2.6366-0.2373
38994_atSOCS2 suppressor of cytokine signaling 2-1.31160.118
160029_atPRKCB1 protein kinase C, beta 1-1.06640.096
1336_s_atPRKCB1 protein kinase C, beta 1-0.98510.0887
41349_atPSEN2 presenilin 2 (Alzheimer disease 4)0.9259-0.0833
1217_g_atPRKCB1 protein kinase C, beta 1-0.87860.0791
794_atPTPN6 protein tyrosine phosphatase, non-receptor type 60.8515-0.0766
39360_atSNX3 sorting nexin 3-0.85080.0766
34679_atBCR breakpoint cluster region0.8156-0.0734
1333_f_atBCR breakpoint cluster region0.7927-0.0713
39428_atLNK lymphocyte adaptor protein-0.78020.0702
40148_atAPBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65-like)0.7691-0.0692
33869_atSTAT5B signal transducer and activator of transcription 5B-0.72070.0649
32625_atNPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)-0.70620.0636
38269_atPRKD2 protein kinase D2-0.57890.0521
40159_r_atNCF1 neutrophil cytosolic factor 1 (47kDa, chronic granulomatous disease, autosomal 1)0.5788-0.0521
227_g_atPRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)0.5762-0.0519
34481_atVAV1 vav 1 oncogene-0.56390.0508
226_atPRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)0.5569-0.0501
2043_s_atBCR breakpoint cluster region0.5505-0.0495
39319_atLCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)-0.53030.0477
37411_atCENTB1 centaurin, beta 1-0.52350.0471
37034_atANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A0.5171-0.0465
506_s_atSTAT5A signal transducer and activator of transcription 5A-0.49820.0448
1087_atEPOR erythropoietin receptor-0.49750.0448
33783_atPLXNB1 plexin B10.4969-0.0447
36885_atSYK spleen tyrosine kinase0.4885-0.044
40585_atADCY7 adenylate cyclase 7-0.48610.0437
1630_s_atSYK spleen tyrosine kinase0.476-0.0428
548_s_atSYK spleen tyrosine kinase0.4653-0.0419
1426_atSLA Src-like-adaptor-0.45750.0412
1478_atITK IL2-inducible T-cell kinase-0.45560.041
41768_atPRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)0.4467-0.0402
1919_atVAV1 vav 1 oncogene-0.44040.0396
39416_atTIP-1 Tax interaction protein 10.4357-0.0392
2081_s_atPRKCQ protein kinase C, theta-0.42680.0384
1706_atARAF1 v-raf murine sarcoma 3611 viral oncogene homolog 1-0.42490.0382
38893_atNCF4 neutrophil cytosolic factor 4, 40kDa0.4242-0.0382
1427_g_atSLA Src-like-adaptor-0.4230.0381
41795_atNCK1 NCK adaptor protein 1-0.42030.0378
40480_s_atFYN FYN oncogene related to SRC, FGR, YES-0.4110.037
36524_atARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4-0.40840.0368
40928_atWSB1 WD repeat and SOCS box-containing 1-0.40630.0366
2039_s_atFYN FYN oncogene related to SRC, FGR, YES-0.40250.0362
39708_atSTAT3 signal transducer and activator of transcription 3 (acute-phase response factor)-0.39050.0351
32716_atDGKA diacylglycerol kinase, alpha 80kDa-0.38340.0345
38894_g_atNCF4 neutrophil cytosolic factor 4, 40kDa0.383-0.0345
1768_s_atCSK c-src tyrosine kinase-0.38120.0343
32860_g_atSTAT1 signal transducer and activator of transcription 1, 91kDa-0.37320.0336
33916_atNISCH nischarin-0.37280.0335
37986_atEPOR erythropoietin receptor-0.3660.0329
35650_atAP162 adapter protein 162-0.36240.0326
1674_atYES1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1-0.36010.0324
32085_atPIP5K3 phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III-0.35890.0323
1816_atRASA2 RAS p21 protein activator 2-0.35560.032
1565_s_atGRB2 growth factor receptor-bound protein 20.3486-0.0314
38242_atBLNK B-cell linker0.3428-0.0309
37961_atPIK3R3 phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)0.34-0.0306
32046_atPRKCD protein kinase C, delta0.3367-0.0303
33134_atADCY3 adenylate cyclase 3-0.33650.0303
33338_atSTAT1 signal transducer and activator of transcription 1, 91kDa-0.33220.0299
38949_atPRKCQ protein kinase C, theta-0.33180.0299
38003_s_atDGKZ diacylglycerol kinase, zeta 104kDa-0.32020.0288
989_atNCK1 NCK adaptor protein 1-0.30890.0278
40521_atRAB2L RAB2, member RAS oncogene family-like-0.30720.0276
473_g_atSTAT5B signal transducer and activator of transcription 5B-0.30690.0276
AFFX-HUMISGF3A/M97935_3_atSTAT1 signal transducer and activator of transcription 1, 91kDa-0.30250.0272
38147_atSH2D1A SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome)-0.29760.0268
36843_atSIPA1 signal-induced proliferation-associated gene 1-0.29620.0267
40101_g_atARHGEF2 rho/rac guanine nucleotide exchange factor (GEF) 20.2952-0.0266
40575_atDLG5 discs, large homolog 5 (Drosophila)-0.29160.0262
36849_atPARG1 PTPL1-associated RhoGAP 1-0.28990.0261
1479_g_atITK IL2-inducible T-cell kinase-0.28880.026
AFFX-HUMISGF3A/M97935_MB_atSTAT1 signal transducer and activator of transcription 1, 91kDa-0.27290.0246
33244_atCHN2 chimerin (chimaerin) 2-0.27190.0245
1602_atPRKCI protein kinase C, iota-0.26980.0243
1011_s_atYWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.2671-0.024
1707_g_atARAF1 v-raf murine sarcoma 3611 viral oncogene homolog 1-0.26340.0237
32219_atTLK1 tousled-like kinase 1-0.25490.0229
38895_i_atNCF4 neutrophil cytosolic factor 4, 40kDa0.2547-0.0229
40458_atSTAT5A signal transducer and activator of transcription 5A-0.24480.022
1810_s_atPRKCD protein kinase C, delta0.2429-0.0219
38800_atSTMN2 stathmin-like 2-0.24220.0218
31945_s_atSH2D1A SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome)-0.23820.0214
32859_atSTAT1 signal transducer and activator of transcription 1, 91kDa-0.23820.0214
36139_atC6orf4 chromosome 6 open reading frame 4-0.23260.0209
31400_atDGKB diacylglycerol kinase, beta 90kDa-0.22790.0205
33339_g_atSTAT1 signal transducer and activator of transcription 1, 91kDa-0.22750.0205
38118_atSHC1 SHC (Src homology 2 domain containing) transforming protein 1-0.22520.0203
40178_atZNF-kaiso kaiso0.2238-0.0201
39273_atSH2D1A SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome)-0.22280.0201
33800_atADCY9 adenylate cyclase 9-0.21960.0198
1716_atKSR kinase suppressor of ras0.2083-0.0187
36264_atMATK megakaryocyte-associated tyrosine kinase-0.20750.0187
38191_atKIAA0645 KIAA0645 gene product0.2022-0.0182
33003_atNCK2 NCK adaptor protein 2-0.19680.0177
40873_atDVL3 dishevelled, dsh homolog 3 (Drosophila)0.1921-0.0173
35632_atCBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b-0.19160.0172
1870_atPTPN11 protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)0.1915-0.0172
36317_atCORO2A coronin, actin binding protein, 2A-0.1910.0172
1244_atSTAT2 signal transducer and activator of transcription 2, 113kDa-0.18980.0171
1339_s_atBCR breakpoint cluster region0.1854-0.0167
1623_s_atFER fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94)-0.18270.0164
32731_atAPBB3 amyloid beta (A4) precursor protein-binding, family B, member 3-0.18130.0163
1269_atPIK3R1 phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.1808-0.0163
41579_s_atPRKCI protein kinase C, iota-0.17930.0161
35484_atLOC92017 similar to RIKEN cDNA 4933437K13-0.17850.0161
396_f_atEPOR erythropoietin receptor-0.1780.016
35015_atCD80 CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)0.1765-0.0159
1369_s_atIL8 interleukin 8-0.17610.0158
38550_atAPBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2)-0.17340.0156
40479_atFYN FYN oncogene related to SRC, FGR, YES-0.1730.0156
34479_atPIK3R3 phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)0.1707-0.0154
1600_atTXK TXK tyrosine kinase-0.17020.0153
32803_atCNIH cornichon homolog (Drosophila)-0.16940.0152
289_atSTAT3 signal transducer and activator of transcription 3 (acute-phase response factor)-0.16850.0152
33238_atLCK lymphocyte-specific protein tyrosine kinase-0.16820.0151
40100_atARHGEF2 rho/rac guanine nucleotide exchange factor (GEF) 20.1654-0.0149
2059_s_atLCK lymphocyte-specific protein tyrosine kinase-0.16120.0145
32669_atSOCS5 suppressor of cytokine signaling 5-0.15860.0143
34686_atADCY2 adenylate cyclase 2 (brain)-0.15650.0141
39383_atADCY6 adenylate cyclase 6-0.15430.0139
34735_atROCK1 Rho-associated, coiled-coil containing protein kinase 1-0.15420.0139
33559_atPTK6 PTK6 protein tyrosine kinase 6-0.15240.0137
906_atSTAT4 signal transducer and activator of transcription 4-0.14970.0135
41715_atPIK3C2B phosphoinositide-3-kinase, class 2, beta polypeptide-0.14850.0134
1208_atPTK6 PTK6 protein tyrosine kinase 6-0.14720.0132
1085_s_atPLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)0.146-0.0131
AFFX-HUMISGF3A/M97935_MA_atSTAT1 signal transducer and activator of transcription 1, 91kDa-0.14280.0129
36246_atADCY8 adenylate cyclase 8 (brain)0.1382-0.0124
1917_atRAF1 v-raf-1 murine leukemia viral oncogene homolog 10.137-0.0123
38219_atCRK v-crk sarcoma virus CT10 oncogene homolog (avian)-0.13580.0122
36935_atRASA1 RAS p21 protein activator (GTPase activating protein) 1-0.13280.012
35373_atPIK3R1 phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.1282-0.0115
33524_atCRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like0.1277-0.0115
1029_s_atTXK TXK tyrosine kinase-0.12580.0113
36509_atPIK3C2A phosphoinositide-3-kinase, class 2, alpha polypeptide0.1255-0.0113
38876_atASB9 ankyrin repeat and SOCS box-containing 9-0.12540.0113
38363_atTYROBP TYRO protein tyrosine kinase binding protein-0.12460.0112
32405_atTHEA thioesterase, adipose associated0.1227-0.011
1806_atMCF2 MCF.2 cell line derived transforming sequence-0.12250.011
31820_atHCLS1 hematopoietic cell-specific Lyn substrate 10.1218-0.011
39874_atGUCY2F guanylate cyclase 2F, retinal-0.12140.0109
35483_atLOC92017 similar to RIKEN cDNA 4933437K130.1202-0.0108
41222_atSTAT6 signal transducer and activator of transcription 6, interleukin-4 induced-0.11970.0108
35133_atFER fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94)-0.11760.0106
901_g_atPLCB4 phospholipase C, beta 4-0.11570.0104
172_atINPP5D inositol polyphosphate-5-phosphatase, 145kDa-0.11470.0103
41592_atSOCS1 suppressor of cytokine signaling 10.1146-0.0103
33025_atC20orf10 chromosome 20 open reading frame 10-0.11450.0103
40167_s_atWSB2 WD repeat and SOCS box-containing 20.1142-0.0103
34937_atDFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)0.1138-0.0102
36216_atSNX4 sorting nexin 40.1129-0.0102
36751_atRGS11 regulator of G-protein signalling 110.1108-0.01
33490_atTXK TXK tyrosine kinase-0.11050.0099
33816_atMYO9B myosin IXB-0.11020.0099
37468_atJAK2 Janus kinase 2 (a protein tyrosine kinase)-0.10910.0098
514_atCBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b-0.1090.0098
40179_atZNF-kaiso kaiso-0.10830.0097
34450_atGUCY2C guanylate cyclase 2C (heat stable enterotoxin receptor)0.1079-0.0097
1675_atRASA1 RAS p21 protein activator (GTPase activating protein) 1-0.1070.0096
35372_r_atIL8 interleukin 8-0.10440.0094
35358_atTENC1 tensin like C1 domain-containing phosphatase-0.10430.0094
35454_atKIAA0450 KIAA0450 gene product-0.10420.0094
388_atPIK3R2 phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta)-0.10240.0092
38443_atPTPN11 protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)-0.10220.0092
40653_atRGS7 regulator of G-protein signalling 7-0.09790.0088
40683_atGRB14 growth factor receptor-bound protein 14-0.09780.0088
735_s_atAKAP13 A kinase (PRKA) anchor protein 13-0.09780.0088
35658_atPSEN1 presenilin 1 (Alzheimer disease 3)-0.09750.0088
32301_atGUCY1A2 guanylate cyclase 1, soluble, alpha 2-0.0950.0086
39962_atCDC42BPA CDC42 binding protein kinase alpha (DMPK-like)0.0943-0.0085
40481_r_atFYN FYN oncogene related to SRC, FGR, YES0.0942-0.0085
40850_atFKBP8 FK506 binding protein 8, 38kDa-0.09360.0084
37136_atAPS adaptor protein with pleckstrin homology and src homology 2 domains0.0917-0.0083
36550_atRIN2 Ras and Rab interactor 20.0911-0.0082
805_atGRAP GRB2-related adaptor protein0.0904-0.0081
32891_atPRKCE protein kinase C, epsilon0.0889-0.008
32449_atDGKQ diacylglycerol kinase, theta 110kDa0.0885-0.008
33855_atGRB2 growth factor receptor-bound protein 20.0878-0.0079
33586_atLink-GEFII Link guanine nucleotide exchange factor II0.0875-0.0079
32302_g_atGUCY1A2 guanylate cyclase 1, soluble, alpha 2-0.08630.0078
35112_atRGS9 regulator of G-protein signalling 9-0.08570.0077
37876_atPRKCN protein kinase C, nu-0.08390.0076
35301_atCRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like-0.08370.0075
41796_atPLCL2 phospholipase C-like 2-0.08290.0075
38370_atTIAM1 T-cell lymphoma invasion and metastasis 1-0.08130.0073
40614_atSHB SHB (Src homology 2 domain containing) adaptor protein B0.0811-0.0073
37654_atSNX17 sorting nexin 17-0.08040.0072
1603_g_atPRKCI protein kinase C, iota0.079-0.0071
36770_atSTAT2 signal transducer and activator of transcription 2, 113kDa-0.07830.007
34254_atRALGDS ral guanine nucleotide dissociation stimulator-0.07750.007
278_atNPR2 natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)-0.07720.0069
34432_atSH2D2A SH2 domain protein 2A-0.07720.0069
39090_atNUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4-0.07670.0069
37045_atSNX19 sorting nexin 19-0.07580.0068
39532_atRIN1 Ras and Rab interactor 1-0.07570.0068
641_atPSEN1 presenilin 1 (Alzheimer disease 3)-0.07530.0068
40166_atWSB2 WD repeat and SOCS box-containing 20.0744-0.0067
1284_atPRKCN protein kinase C, nu0.0734-0.0066
35321_atTLK2 tousled-like kinase 2-0.07240.0065
32206_atCDC42BPA CDC42 binding protein kinase alpha (DMPK-like)-0.0710.0064
1457_atJAK1 Janus kinase 1 (a protein tyrosine kinase)-0.07030.0063
1782_s_atSTMN1 stathmin 1/oncoprotein 180.0697-0.0063
37460_atTIAM1 T-cell lymphoma invasion and metastasis 10.0697-0.0063
1780_atFGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog-0.06970.0063
39188_atGUCY2F guanylate cyclase 2F, retinal-0.06930.0062
38190_r_atKIAA0645 KIAA0645 gene product0.0691-0.0062
37128_atSOCS7 suppressor of cytokine signaling 7-0.06680.006
1871_g_atPTPN11 protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)-0.0660.0059
35147_atMCF2L MCF.2 cell line derived transforming sequence-like-0.06540.0059
40099_atARHGEF2 rho/rac guanine nucleotide exchange factor (GEF) 2-0.06490.0058
415_atCRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like-0.06350.0057
515_s_atCBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b0.0629-0.0057
33883_atEFS embryonal Fyn-associated substrate-0.06250.0056
34674_atS100A1 S100 calcium binding protein A10.061-0.0055
32685_atRALGPS1A Ral guanine nucleotide exchange factor RalGPS1A0.0604-0.0054
31875_atASB1 ankyrin repeat and SOCS box-containing 1-0.06030.0054
163_atDVL1 dishevelled, dsh homolog 1 (Drosophila)-0.06020.0054
1976_s_atFES feline sarcoma oncogene-0.05980.0054
1778_g_atRIN1 Ras and Rab interactor 10.0581-0.0052
32996_g_atASB4 ankyrin repeat and SOCS box-containing 40.0579-0.0052
38957_atDCAMKL1 doublecortin and CaM kinase-like 1-0.05720.0051
1437_atPRKCA protein kinase C, alpha-0.05690.0051
772_atCRK v-crk sarcoma virus CT10 oncogene homolog (avian)-0.05570.005
34197_atPIK3R2 phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta)-0.05560.005
40212_atKSR kinase suppressor of ras0.0551-0.005
36598_s_atINPPL1 inositol polyphosphate phosphatase-like 10.0548-0.0049
40024_atSTAC src homology three (SH3) and cysteine rich domain-0.05480.0049
37806_atSHANK2 SH3 and multiple ankyrin repeat domains 2-0.05380.0048
37596_atPLCD1 phospholipase C, delta 1-0.05290.0048
1204_atDGKG diacylglycerol kinase, gamma 90kDa0.0521-0.0047
34942_atFLJ38993 hypothetical protein FLJ38993-0.05180.0047
37180_atPLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)0.0506-0.0046
38145_atINADL InaD-like protein0.0499-0.0045
472_atSTAT5B signal transducer and activator of transcription 5B-0.04940.0044
35580_atADCY1 adenylate cyclase 1 (brain)0.0484-0.0044
40566_atPRKCA protein kinase C, alpha0.0483-0.0043
363_atPRKCG protein kinase C, gamma-0.04820.0043
41584_atNUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 30.0479-0.0043
33707_atPLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)-0.04690.0042
33002_atNCK2 NCK adaptor protein 2-0.04680.0042
1266_s_atLCK lymphocyte-specific protein tyrosine kinase0.046-0.0041
40539_atMYO9B myosin IXB-0.04580.0041
35335_atROCK2 Rho-associated, coiled-coil containing protein kinase 20.0456-0.0041
642_s_atPSEN1 presenilin 1 (Alzheimer disease 3)0.0454-0.0041
408_atCXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)-0.04510.0041
32304_atPRKCA protein kinase C, alpha-0.04470.004
417_atPRKCE protein kinase C, epsilon0.0444-0.004
474_atDGKE diacylglycerol kinase, epsilon 64kDa-0.04420.004
1182_atPLCL1 phospholipase C-like 1-0.04330.0039
40605_atSNX4 sorting nexin 40.043-0.0039
40330_atPLCE1 phospholipase C, epsilon 10.0427-0.0038
962_atBMX BMX non-receptor tyrosine kinase-0.04230.0038
35622_atSLI neuronal Shc adaptor homolog-0.04160.0037
1084_atABL2 v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)-0.04110.0037
39457_r_atSNX4 sorting nexin 4-0.0410.0037
41117_s_atSLC9A3R2 solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 2-0.0410.0037
41593_atSOCS1 suppressor of cytokine signaling 10.0409-0.0037
38742_s_atRAF1 v-raf-1 murine leukemia viral oncogene homolog 10.0403-0.0036
41462_atSNX2 sorting nexin 2-0.040.0036
33164_atTESK2 testis-specific kinase 2-0.03960.0036
39270_atCD209L CD209 antigen-like-0.0390.0035
364_s_atPLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)-0.03890.0035
37973_atSNX13 sorting nexin 13-0.03820.0034
AFFX-HUMISGF3A/M97935_5_atSTAT1 signal transducer and activator of transcription 1, 91kDa-0.03810.0034
1783_atRIN2 Ras and Rab interactor 20.0375-0.0034
35023_atFRK fyn-related kinase-0.03660.0033
1415_atEFS embryonal Fyn-associated substrate0.0361-0.0033
39222_atPIK3C2G phosphoinositide-3-kinase, class 2, gamma polypeptide-0.03550.0032
39601_atRASSF1 Ras association (RalGDS/AF-6) domain family 1-0.03540.0032
38865_atGRAP2 GRB2-related adaptor protein 2-0.03510.0032
32385_atROCK1 Rho-associated, coiled-coil containing protein kinase 10.035-0.0032
32995_atASB4 ankyrin repeat and SOCS box-containing 40.034-0.0031
40929_atWSB1 WD repeat and SOCS box-containing 10.0334-0.003
38189_s_atKIAA0645 KIAA0645 gene product-0.03320.003
33004_g_atNCK2 NCK adaptor protein 20.0318-0.0029
37052_atDGKG diacylglycerol kinase, gamma 90kDa-0.03170.0029
38743_f_atRAF1 v-raf-1 murine leukemia viral oncogene homolog 1-0.02970.0027
36812_atBCAR3 breast cancer anti-estrogen resistance 3-0.02940.0027
39656_atRGS6 regulator of G-protein signalling 60.0291-0.0026
37570_atSNX15 sorting nexin 150.0275-0.0025
32047_atDFFA DNA fragmentation factor, 45kDa, alpha polypeptide-0.02650.0024
37847_atUSH1C Usher syndrome 1C (autosomal recessive, severe)-0.02530.0023
1082_atPLCG1 phospholipase C, gamma 1-0.02530.0023
33600_atGRAP GRB2-related adaptor protein-0.02340.0021
1680_atGRB7 growth factor receptor-bound protein 70.0197-0.0018
1823_g_atPRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)-0.01950.0018
37301_atPRKCB1 protein kinase C, beta 1-0.01950.0018
40968_atSOCS3 suppressor of cytokine signaling 30.019-0.0017
37615_atGRB10 growth factor receptor-bound protein 100.0187-0.0017
40149_atSH2B SH2-B homolog0.0179-0.0016
39958_atSOCS6 suppressor of cytokine signaling 6-0.01770.0016
1822_atPRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)-0.01760.0016
37808_atSNX7 sorting nexin 7-0.01690.0015
40969_atSOCS3 suppressor of cytokine signaling 3-0.01620.0015
32862_atRASA3 RAS p21 protein activator 3-0.01590.0014
1777_atRIN1 Ras and Rab interactor 1-0.01570.0014
1511_atSHC3 src homology 2 domain containing transforming protein C3-0.01290.0012
32994_atASB4 ankyrin repeat and SOCS box-containing 40.0127-0.0011
31977_atGUCY2D guanylate cyclase 2D, membrane (retina-specific)0.0103-9e-04
31681_atEPOR erythropoietin receptor-0.019e-04
35980_atPLCB1 phospholipase C, beta 1 (phosphoinositide-specific)-0.00999e-04
1807_g_atMCF2 MCF.2 cell line derived transforming sequence0.0072-6e-04
322_atPIK3R3 phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)-0.0076e-04
38110_atSDCBP syndecan binding protein (syntenin)0.0066-6e-04
900_atPLCB4 phospholipase C, beta 4-0.00575e-04
40512_atCHN1 chimerin (chimaerin) 10.0048-4e-04
41594_atJAK1 Janus kinase 1 (a protein tyrosine kinase)-0.00333e-04
511_s_atFRK fyn-related kinase0.0022-2e-04
1704_atVAV2 vav 2 oncogene-0.00111e-04
845_atSTAT6 signal transducer and activator of transcription 6, interleukin-4 induced-0.0011e-04

Performance on training data

 SensitivitySpecificity
E2A-PBX111
other11

Performance on test data

 SensitivitySpecificity
E2A-PBX10.888890.99
other0.990.88889

Predictions

 ClassE2A-PBX1otherPredictionn
BCR-ABL-1other01 other
BCR-ABL-2other01 other
BCR-ABL-3 (testset)other01 other
BCR-ABL-4other01 other
BCR-ABL-5other01 other
BCR-ABL-6other01 other
BCR-ABL-7other01 other
BCR-ABL-8other01 other
BCR-ABL-9other01 other
BCR-ABL-C1other01 other
BCR-ABL-Hyperdip-10other01 other
BCR-ABL-Hyperdip-R5other01 other
BCR-ABL-R1other01 other
BCR-ABL-R2 (testset)other01 other
BCR-ABL-R3other01 other
E2A-PBX1-10E2A-PBX10.999270.00073 E2A-PBX1
E2A-PBX1-11 (testset)E2A-PBX110 E2A-PBX1
E2A-PBX1-12E2A-PBX10.623970.37603 E2A-PBX1
E2A-PBX1-13 (testset)E2A-PBX110 E2A-PBX1
E2A-PBX1-1E2A-PBX10.999991e-05 E2A-PBX1
E2A-PBX1-2E2A-PBX110 E2A-PBX1
E2A-PBX1-3E2A-PBX110 E2A-PBX1
E2A-PBX1-4 (testset)E2A-PBX110 E2A-PBX1
E2A-PBX1-5 (testset)E2A-PBX10.994410.00559 E2A-PBX1
E2A-PBX1-6E2A-PBX110 E2A-PBX1
E2A-PBX1-7E2A-PBX110 E2A-PBX1
E2A-PBX1-8E2A-PBX110 E2A-PBX1
E2A-PBX1-9E2A-PBX110 E2A-PBX1
E2A-PBX1-2M1E2A-PBX110 E2A-PBX1
E2A-PBX1-C10 (testset)E2A-PBX110 E2A-PBX1
E2A-PBX1-C11 (testset)E2A-PBX10.98610.0139 E2A-PBX1
E2A-PBX1-C12E2A-PBX110 E2A-PBX1
E2A-PBX1-C1 (testset)E2A-PBX10.104330.89567 other
E2A-PBX1-C2E2A-PBX110 E2A-PBX1
E2A-PBX1-C3E2A-PBX110 E2A-PBX1
E2A-PBX1-C4 (testset)E2A-PBX110 E2A-PBX1
E2A-PBX1-C5E2A-PBX110 E2A-PBX1
E2A-PBX1-C6E2A-PBX10.999991e-05 E2A-PBX1
E2A-PBX1-C7E2A-PBX110 E2A-PBX1
E2A-PBX1-C8E2A-PBX110 E2A-PBX1
E2A-PBX1-C9 (testset)E2A-PBX110 E2A-PBX1
E2A-PBX1-R1E2A-PBX110 E2A-PBX1
Hyperdip-50-10 (testset)other01 other
Hyperdip-50-11 (testset)other01 other
Hyperdip-50-12other2e-050.99998 other
Hyperdip-50-13 (testset)other01 other
Hyperdip-50-14other01 other
Hyperdip-50-1 (testset)other01 other
Hyperdip-50-2 (testset)other01 other
Hyperdip-50-3other01 other
Hyperdip-50-4 (testset)other01 other
Hyperdip-50-5other01 other
Hyperdip-50-6other01 other
Hyperdip-50-7other01 other
Hyperdip-50-8 (testset)other01 other
Hyperdip-50-9other7e-050.99993 other
Hyperdip-50-2M1 (testset)other01 other
Hyperdip-50-2M2 (testset)other01 other
Hyperdip-50-C10other01 other
Hyperdip-50-C11other01 other
Hyperdip-50-C12other01 other
Hyperdip-50-C13other01 other
Hyperdip-50-C14other01 other
Hyperdip-50-C15other01 other
Hyperdip-50-C16 (testset)other01 other
Hyperdip-50-C17other01 other
Hyperdip-50-C18other01 other
Hyperdip-50-C19 (testset)other01 other
Hyperdip-50-C1other01 other
Hyperdip-50-C20other01 other
Hyperdip-50-C21other01 other
Hyperdip-50-C22other01 other
Hyperdip-50-C23other01 other
Hyperdip-50-C24 (testset)other01 other
Hyperdip-50-C25other01 other
Hyperdip-50-C26 (testset)other01 other
Hyperdip-50-C27-N (testset)other01 other
Hyperdip-50-C28other01 other
Hyperdip-50-C29other01 other
Hyperdip-50-C2 (testset)other01 other
Hyperdip-50-C30other5e-050.99995 other
Hyperdip-50-C31other01 other
Hyperdip-50-C32 (testset)other01 other
Hyperdip-50-C33other01 other
Hyperdip-50-C34other01 other
Hyperdip-50-C35 (testset)other01 other
Hyperdip-50-C36other01 other
Hyperdip-50-C37other01 other
Hyperdip-50-C38 (testset)other01 other
Hyperdip-50-C39other01 other
Hyperdip-50-C3other01 other
Hyperdip-50-C40 (testset)other01 other
Hyperdip-50-C41other01 other
Hyperdip-50-C42other01 other
Hyperdip-50-C43 (testset)other01 other
Hyperdip-50-C4other01 other
Hyperdip-50-C5 (testset)other01 other
Hyperdip-50-C6other01 other
Hyperdip-50-C7other01 other
Hyperdip-50-C8other01 other
Hyperdip-50-C9other01 other
Hyperdip-50-R1other01 other
Hyperdip-50-R2other01 other
Hyperdip-50-R3other2e-050.99998 other
Hyperdip-50-R4 (testset)other01 other
Hyperdip-50-R5 (testset)other01 other
Hyperdip47-50-1other01 other
Hyperdip47-50-2 (testset)other01 other
Hyperdip47-50-3other0.001730.99827 other
Hyperdip47-50-2M1 (testset)other01 other
Hyperdip47-50-C10other01 other
Hyperdip47-50-C11other01 other
Hyperdip47-50-C12other01 other
Hyperdip47-50-C13 (testset)other5e-050.99995 other
Hyperdip47-50-C14-Nother01 other
Hyperdip47-50-C15 (testset)other2e-050.99998 other
Hyperdip47-50-C16 (testset)other1e-050.99999 other
Hyperdip47-50-C17other01 other
Hyperdip47-50-C18 (testset)other01 other
Hyperdip47-50-C19other0.072040.92796 other
Hyperdip47-50-C1other2e-050.99998 other
Hyperdip47-50-C2other01 other
Hyperdip47-50-C3-Nother01 other
Hyperdip47-50-C4other01 other
Hyperdip47-50-C5 (testset)other0.766380.23362 E2A-PBX1
Hyperdip47-50-C6other01 other
Hyperdip47-50-C7 (testset)other0.366710.63329 other
Hyperdip47-50-C8other01 other
Hyperdip47-50-C9 (testset)other01 other
Hypodip-1 (testset)other01 other
Hypodip-2 (testset)other01 other
Hypodip-2M1other01 other
Hypodip-C1other01 other
Hypodip-C2other01 other
Hypodip-C3other3e-050.99997 other
Hypodip-C4other01 other
Hypodip-C5other01 other
Hypodip-C6other01 other
MLL-1other1e-050.99999 other
MLL-2other0.000550.99945 other
MLL-3 (testset)other01 other
MLL-4other01 other
MLL-5other2e-050.99998 other
MLL-6other01 other
MLL-7 (testset)other01 other
MLL-8other6e-050.99994 other
MLL-2M1other01 other
MLL-2M2other0.000740.99926 other
MLL-C1other0.013720.98628 other
MLL-C2 (testset)other01 other
MLL-C3 (testset)other01 other
MLL-C4other0.000690.99931 other
MLL-C5other01 other
MLL-C6 (testset)other1e-040.9999 other
MLL-R1other0.001520.99848 other
MLL-R2 (testset)other0.000190.99981 other
MLL-R3 (testset)other0.001110.99889 other
MLL-R4 (testset)other01 other
Normal-1other6e-050.99994 other
Normal-2other01 other
Normal-3other01 other
Normal-C1-Nother1e-050.99999 other
Normal-C10other6e-050.99994 other
Normal-C11-N (testset)other1e-050.99999 other
Normal-C12 (testset)other0.168010.83199 other
Normal-C2-Nother01 other
Normal-C3-Nother0.000650.99935 other
Normal-C4-Nother0.002860.99714 other
Normal-C5 (testset)other01 other
Normal-C6other01 other
Normal-C7-Nother1e-040.9999 other
Normal-C8other01 other
Normal-C9 (testset)other01 other
Normal-R1other01 other
Normal-R2-Nother01 other
Normal-R3 (testset)other01 other
Pseudodip-1 (testset)other01 other
Pseudodip-2other01 other
Pseudodip-3other01 other
Pseudodip-4other01 other
Pseudodip-5other01 other
Pseudodip-6other6e-050.99994 other
Pseudodip-7 (testset)other01 other
Pseudodip-8-N (testset)other0.063130.93687 other
Pseudodip-9other01 other
Pseudodip-C10other01 other
Pseudodip-C11other01 other
Pseudodip-C12other01 other
Pseudodip-C13other01 other
Pseudodip-C14 (testset)other7e-040.9993 other
Pseudodip-C15other01 other
Pseudodip-C16-N (testset)other01 other
Pseudodip-C17 (testset)other01 other
Pseudodip-C18other1e-050.99999 other
Pseudodip-C19other01 other
Pseudodip-C1other01 other
Pseudodip-C2-N (testset)other1e-050.99999 other
Pseudodip-C3other01 other
Pseudodip-C4other01 other
Pseudodip-C5 (testset)other01 other
Pseudodip-C6other3e-050.99997 other
Pseudodip-C7 (testset)other01 other
Pseudodip-C8 (testset)other0.000330.99967 other
Pseudodip-C9other01 other
Pseudodip-R1-Nother01 other
T-ALL-10other01 other
T-ALL-1other01 other
T-ALL-2other0.001810.99819 other
T-ALL-3other01 other
T-ALL-4 (testset)other01 other
T-ALL-5other01 other
T-ALL-6other01 other
T-ALL-7 (testset)other01 other
T-ALL-8other01 other
T-ALL-9 (testset)other01 other
T-ALL-2M1other01 other
T-ALL-C10other01 other
T-ALL-C11other01 other
T-ALL-C12other01 other
T-ALL-C13other01 other
T-ALL-C14other01 other
T-ALL-C15 (testset)other01 other
T-ALL-C16other01 other
T-ALL-C17other01 other
T-ALL-C18 (testset)other01 other
T-ALL-C19 (testset)other01 other
T-ALL-C1 (testset)other01 other
T-ALL-C20other01 other
T-ALL-C21other01 other
T-ALL-C22other01 other
T-ALL-C23other01 other
T-ALL-C24other01 other
T-ALL-C25other01 other
T-ALL-C26 (testset)other01 other
T-ALL-C2 (testset)other01 other
T-ALL-C3other01 other
T-ALL-C4 (testset)other01 other
T-ALL-C5 (testset)other01 other
T-ALL-C6 (testset)other01 other
T-ALL-C7other01 other
T-ALL-C8other01 other
T-ALL-C9other01 other
T-ALL-R1other01 other
T-ALL-R2other01 other
T-ALL-R3other01 other
T-ALL-R4other01 other
T-ALL-R5 (testset)other01 other
T-ALL-R6other01 other
TEL-AML1-10 (testset)other01 other
TEL-AML1-11other01 other
TEL-AML1-12 (testset)other01 other
TEL-AML1-13other01 other
TEL-AML1-14other01 other
TEL-AML1-1 (testset)other01 other
TEL-AML1-2other01 other
TEL-AML1-3 (testset)other01 other
TEL-AML1-4other01 other
TEL-AML1-5other4e-050.99996 other
TEL-AML1-6 (testset)other0.000140.99986 other
TEL-AML1-7 (testset)other01 other
TEL-AML1-8other01 other
TEL-AML1-9other01 other
TEL-AML1-2M1 (testset)other01 other
TEL-AML1-2M2other01 other
TEL-AML1-2M3other01 other
TEL-AML1-2M4 (testset)other01 other
TEL-AML1-2M5other01 other
TEL-AML1-C10 (testset)other01 other
TEL-AML1-C11other01 other
TEL-AML1-C12 (testset)other01 other
TEL-AML1-C13 (testset)other01 other
TEL-AML1-C14other01 other
TEL-AML1-C15other01 other
TEL-AML1-C16other01 other
TEL-AML1-C17 (testset)other01 other
TEL-AML1-C18 (testset)other01 other
TEL-AML1-C19other01 other
TEL-AML1-C1other01 other
TEL-AML1-C20other01 other
TEL-AML1-C21other01 other
TEL-AML1-C22other01 other
TEL-AML1-C23other01 other
TEL-AML1-C24other01 other
TEL-AML1-C25 (testset)other01 other
TEL-AML1-C26other01 other
TEL-AML1-C27 (testset)other01 other
TEL-AML1-C28other01 other
TEL-AML1-C29 (testset)other01 other
TEL-AML1-C2other01 other
TEL-AML1-C30other01 other
TEL-AML1-C31 (testset)other01 other
TEL-AML1-C32other01 other
TEL-AML1-C33other01 other
TEL-AML1-C34 (testset)other01 other
TEL-AML1-C35other01 other
TEL-AML1-C36other01 other
TEL-AML1-C37other01 other
TEL-AML1-C38 (testset)other01 other
TEL-AML1-C39other01 other
TEL-AML1-C3 (testset)other01 other
TEL-AML1-C40 (testset)other01 other
TEL-AML1-C41other01 other
TEL-AML1-C42 (testset)other01 other
TEL-AML1-C43other01 other
TEL-AML1-C44 (testset)other01 other
TEL-AML1-C45other1e-050.99999 other
TEL-AML1-C46 (testset)other01 other
TEL-AML1-C47other01 other
TEL-AML1-C48other01 other
TEL-AML1-C49other01 other
TEL-AML1-C4other01 other
TEL-AML1-C50other01 other
TEL-AML1-C51other01 other
TEL-AML1-C52other01 other
TEL-AML1-C53other01 other
TEL-AML1-C54other01 other
TEL-AML1-C55other01 other
TEL-AML1-C56other01 other
TEL-AML1-C57 (testset)other01 other
TEL-AML1-C5 (testset)other01 other
TEL-AML1-C6other01 other
TEL-AML1-C7other01 other
TEL-AML1-C8other01 other
TEL-AML1-C9 (testset)other01 other
TEL-AML1-R1other01 other
TEL-AML1-R2other01 other
TEL-AML1-R3 (testset)other01 other

 


Generated by StAM on Tue Sep 7 18:22:57 2004