GO:0007242

GO:0007242

intracellular signaling cascade

Biological Process

Parent node

GO:0007165	signal transduction

8 child nodes

ID	Term	Weight
GO:0001508	regulation of action potential	0.00000
GO:0009755	hormone mediated signaling	0.00000
GO:0030522	intracellular receptor-mediated signaling pathway	0.00000
GO:0007263	nitric oxide mediated signal transduction	0.00000
GO:0007243	protein kinase cascade	0.00000
GO:0019932	second-messenger-mediated signaling	0.00000
GO:0007264	small GTPase mediated signal transduction	0.25037
GO:0007242a	intracellular signaling cascade (annotated genes)	0.7496287

Performance on training data

• Error rate: 0
• Performance: 0.02537
• Redundancy: 4.34977

	Sensitivity	Specificity
E2A-PBX1	1	1
other	1	1

Performance on test data

• Error rate: 0.01835
• Performance: 0.08891
• Redundancy: 4.20309

	Sensitivity	Specificity
E2A-PBX1	0.88889	0.99
other	0.99	0.88889

Predictions

	Class	E2A-PBX1	other	Predictionn
BCR-ABL-1	other	0.00098	0.99902	other
BCR-ABL-2	other	0.00101	0.99899	other
BCR-ABL-3 (testset)	other	4e-05	0.99996	other
BCR-ABL-4	other	4e-05	0.99996	other
BCR-ABL-5	other	7e-05	0.99993	other
BCR-ABL-6	other	4e-05	0.99996	other
BCR-ABL-7	other	0.00294	0.99706	other
BCR-ABL-8	other	0.00123	0.99877	other
BCR-ABL-9	other	0.00165	0.99835	other
BCR-ABL-C1	other	0.0011	0.9989	other
BCR-ABL-Hyperdip-10	other	1e-05	0.99999	other
BCR-ABL-Hyperdip-R5	other	1e-05	0.99999	other
BCR-ABL-R1	other	0.00093	0.99907	other
BCR-ABL-R2 (testset)	other	5e-05	0.99995	other
BCR-ABL-R3	other	0.00115	0.99885	other
E2A-PBX1-10	E2A-PBX1	0.92249	0.07751	E2A-PBX1
E2A-PBX1-11 (testset)	E2A-PBX1	0.95343	0.04657	E2A-PBX1
E2A-PBX1-12	E2A-PBX1	0.58829	0.41171	E2A-PBX1
E2A-PBX1-13 (testset)	E2A-PBX1	0.89888	0.10112	E2A-PBX1
E2A-PBX1-1	E2A-PBX1	0.99405	0.00595	E2A-PBX1
E2A-PBX1-2	E2A-PBX1	0.93151	0.06849	E2A-PBX1
E2A-PBX1-3	E2A-PBX1	0.91972	0.08028	E2A-PBX1
E2A-PBX1-4 (testset)	E2A-PBX1	0.86725	0.13275	E2A-PBX1
E2A-PBX1-5 (testset)	E2A-PBX1	0.95661	0.04339	E2A-PBX1
E2A-PBX1-6	E2A-PBX1	0.99666	0.00334	E2A-PBX1
E2A-PBX1-7	E2A-PBX1	0.9061	0.0939	E2A-PBX1
E2A-PBX1-8	E2A-PBX1	0.90152	0.09848	E2A-PBX1
E2A-PBX1-9	E2A-PBX1	0.98406	0.01594	E2A-PBX1
E2A-PBX1-2M1	E2A-PBX1	0.95348	0.04652	E2A-PBX1
E2A-PBX1-C10 (testset)	E2A-PBX1	0.90047	0.09953	E2A-PBX1
E2A-PBX1-C11 (testset)	E2A-PBX1	0.78277	0.21723	E2A-PBX1
E2A-PBX1-C12	E2A-PBX1	0.91359	0.08641	E2A-PBX1
E2A-PBX1-C1 (testset)	E2A-PBX1	0.1106	0.8894	other
E2A-PBX1-C2	E2A-PBX1	0.98853	0.01147	E2A-PBX1
E2A-PBX1-C3	E2A-PBX1	0.86061	0.13939	E2A-PBX1
E2A-PBX1-C4 (testset)	E2A-PBX1	0.89171	0.10829	E2A-PBX1
E2A-PBX1-C5	E2A-PBX1	0.9429	0.0571	E2A-PBX1
E2A-PBX1-C6	E2A-PBX1	0.81705	0.18295	E2A-PBX1
E2A-PBX1-C7	E2A-PBX1	0.99199	0.00801	E2A-PBX1
E2A-PBX1-C8	E2A-PBX1	0.98024	0.01976	E2A-PBX1
E2A-PBX1-C9 (testset)	E2A-PBX1	0.97038	0.02962	E2A-PBX1
E2A-PBX1-R1	E2A-PBX1	0.9742	0.0258	E2A-PBX1
Hyperdip-50-10 (testset)	other	0.00024	0.99976	other
Hyperdip-50-11 (testset)	other	0.00111	0.99889	other
Hyperdip-50-12	other	0.00112	0.99888	other
Hyperdip-50-13 (testset)	other	0.00091	0.99909	other
Hyperdip-50-14	other	4e-05	0.99996	other
Hyperdip-50-1 (testset)	other	0.00024	0.99976	other
Hyperdip-50-2 (testset)	other	0.00018	0.99982	other
Hyperdip-50-3	other	4e-05	0.99996	other
Hyperdip-50-4 (testset)	other	0.00274	0.99726	other
Hyperdip-50-5	other	8e-05	0.99992	other
Hyperdip-50-6	other	8e-05	0.99992	other
Hyperdip-50-7	other	0.00389	0.99611	other
Hyperdip-50-8 (testset)	other	0.00022	0.99978	other
Hyperdip-50-9	other	0.01253	0.98747	other
Hyperdip-50-2M1 (testset)	other	0.00034	0.99966	other
Hyperdip-50-2M2 (testset)	other	0.00028	0.99972	other
Hyperdip-50-C10	other	0.0023	0.9977	other
Hyperdip-50-C11	other	0.00012	0.99988	other
Hyperdip-50-C12	other	0.00165	0.99835	other
Hyperdip-50-C13	other	0.00026	0.99974	other
Hyperdip-50-C14	other	0.00023	0.99977	other
Hyperdip-50-C15	other	0.00099	0.99901	other
Hyperdip-50-C16 (testset)	other	0.00293	0.99707	other
Hyperdip-50-C17	other	5e-05	0.99995	other
Hyperdip-50-C18	other	5e-05	0.99995	other
Hyperdip-50-C19 (testset)	other	4e-05	0.99996	other
Hyperdip-50-C1	other	0.00029	0.99971	other
Hyperdip-50-C20	other	0.00014	0.99986	other
Hyperdip-50-C21	other	1e-05	0.99999	other
Hyperdip-50-C22	other	0.00019	0.99981	other
Hyperdip-50-C23	other	0.00052	0.99948	other
Hyperdip-50-C24 (testset)	other	0.00562	0.99438	other
Hyperdip-50-C25	other	5e-05	0.99995	other
Hyperdip-50-C26 (testset)	other	0.00026	0.99974	other
Hyperdip-50-C27-N (testset)	other	0.00093	0.99907	other
Hyperdip-50-C28	other	0.0015	0.9985	other
Hyperdip-50-C29	other	0.00123	0.99877	other
Hyperdip-50-C2 (testset)	other	1e-04	0.9999	other
Hyperdip-50-C30	other	0.00118	0.99882	other
Hyperdip-50-C31	other	1e-04	0.9999	other
Hyperdip-50-C32 (testset)	other	1e-05	0.99999	other
Hyperdip-50-C33	other	0.00747	0.99253	other
Hyperdip-50-C34	other	2e-05	0.99998	other
Hyperdip-50-C35 (testset)	other	0.00076	0.99924	other
Hyperdip-50-C36	other	3e-05	0.99997	other
Hyperdip-50-C37	other	0.00047	0.99953	other
Hyperdip-50-C38 (testset)	other	3e-05	0.99997	other
Hyperdip-50-C39	other	0.00054	0.99946	other
Hyperdip-50-C3	other	0.00527	0.99473	other
Hyperdip-50-C40 (testset)	other	0.00098	0.99902	other
Hyperdip-50-C41	other	9e-05	0.99991	other
Hyperdip-50-C42	other	1e-05	0.99999	other
Hyperdip-50-C43 (testset)	other	0.01026	0.98974	other
Hyperdip-50-C4	other	0.00025	0.99975	other
Hyperdip-50-C5 (testset)	other	0.00113	0.99887	other
Hyperdip-50-C6	other	0.00032	0.99968	other
Hyperdip-50-C7	other	0.00044	0.99956	other
Hyperdip-50-C8	other	0.00119	0.99881	other
Hyperdip-50-C9	other	9e-05	0.99991	other
Hyperdip-50-R1	other	1e-04	0.9999	other
Hyperdip-50-R2	other	0.00074	0.99926	other
Hyperdip-50-R3	other	0.01287	0.98713	other
Hyperdip-50-R4 (testset)	other	0.00053	0.99947	other
Hyperdip-50-R5 (testset)	other	0.00026	0.99974	other
Hyperdip47-50-1	other	4e-05	0.99996	other
Hyperdip47-50-2 (testset)	other	0.00052	0.99948	other
Hyperdip47-50-3	other	0.04359	0.95641	other
Hyperdip47-50-2M1 (testset)	other	0.00012	0.99988	other
Hyperdip47-50-C10	other	6e-05	0.99994	other
Hyperdip47-50-C11	other	0.00018	0.99982	other
Hyperdip47-50-C12	other	0.00059	0.99941	other
Hyperdip47-50-C13 (testset)	other	0.02632	0.97368	other
Hyperdip47-50-C14-N	other	0.00034	0.99966	other
Hyperdip47-50-C15 (testset)	other	0.00051	0.99949	other
Hyperdip47-50-C16 (testset)	other	0.00059	0.99941	other
Hyperdip47-50-C17	other	0.00037	0.99963	other
Hyperdip47-50-C18 (testset)	other	0.00048	0.99952	other
Hyperdip47-50-C19	other	0.07997	0.92003	other
Hyperdip47-50-C1	other	0.02166	0.97834	other
Hyperdip47-50-C2	other	0.00086	0.99914	other
Hyperdip47-50-C3-N	other	0.00013	0.99987	other
Hyperdip47-50-C4	other	0.00101	0.99899	other
Hyperdip47-50-C5 (testset)	other	0.58587	0.41413	E2A-PBX1
Hyperdip47-50-C6	other	2e-05	0.99998	other
Hyperdip47-50-C7 (testset)	other	0.30237	0.69763	other
Hyperdip47-50-C8	other	0.00011	0.99989	other
Hyperdip47-50-C9 (testset)	other	2e-05	0.99998	other
Hypodip-1 (testset)	other	0.00251	0.99749	other
Hypodip-2 (testset)	other	0.00142	0.99858	other
Hypodip-2M1	other	0.00255	0.99745	other
Hypodip-C1	other	6e-05	0.99994	other
Hypodip-C2	other	0.00355	0.99645	other
Hypodip-C3	other	0.00242	0.99758	other
Hypodip-C4	other	4e-04	0.9996	other
Hypodip-C5	other	0.00173	0.99827	other
Hypodip-C6	other	0.00096	0.99904	other
MLL-1	other	0.00044	0.99956	other
MLL-2	other	0.00144	0.99856	other
MLL-3 (testset)	other	2e-05	0.99998	other
MLL-4	other	0.00044	0.99956	other
MLL-5	other	0.00049	0.99951	other
MLL-6	other	9e-05	0.99991	other
MLL-7 (testset)	other	0.00159	0.99841	other
MLL-8	other	0.0044	0.9956	other
MLL-2M1	other	5e-05	0.99995	other
MLL-2M2	other	0.0029	0.9971	other
MLL-C1	other	0.01259	0.98741	other
MLL-C2 (testset)	other	8e-05	0.99992	other
MLL-C3 (testset)	other	0.00192	0.99808	other
MLL-C4	other	0.00632	0.99368	other
MLL-C5	other	8e-04	0.9992	other
MLL-C6 (testset)	other	0.00943	0.99057	other
MLL-R1	other	0.00295	0.99705	other
MLL-R2 (testset)	other	0.00294	0.99706	other
MLL-R3 (testset)	other	0.00106	0.99894	other
MLL-R4 (testset)	other	0.00144	0.99856	other
Normal-1	other	0.00766	0.99234	other
Normal-2	other	2e-05	0.99998	other
Normal-3	other	0.00011	0.99989	other
Normal-C1-N	other	0.00581	0.99419	other
Normal-C10	other	0.00469	0.99531	other
Normal-C11-N (testset)	other	0.00123	0.99877	other
Normal-C12 (testset)	other	0.14549	0.85451	other
Normal-C2-N	other	0.00075	0.99925	other
Normal-C3-N	other	0.01279	0.98721	other
Normal-C4-N	other	0.00535	0.99465	other
Normal-C5 (testset)	other	0.00026	0.99974	other
Normal-C6	other	0.00232	0.99768	other
Normal-C7-N	other	0.00092	0.99908	other
Normal-C8	other	0.00015	0.99985	other
Normal-C9 (testset)	other	0.00418	0.99582	other
Normal-R1	other	1e-04	0.9999	other
Normal-R2-N	other	0.00024	0.99976	other
Normal-R3 (testset)	other	0.01163	0.98837	other
Pseudodip-1 (testset)	other	0.00056	0.99944	other
Pseudodip-2	other	0.00162	0.99838	other
Pseudodip-3	other	0.00298	0.99702	other
Pseudodip-4	other	0.00038	0.99962	other
Pseudodip-5	other	0.00026	0.99974	other
Pseudodip-6	other	0.00265	0.99735	other
Pseudodip-7 (testset)	other	5e-05	0.99995	other
Pseudodip-8-N (testset)	other	0.04795	0.95205	other
Pseudodip-9	other	0.00981	0.99019	other
Pseudodip-C10	other	0.00045	0.99955	other
Pseudodip-C11	other	3e-04	0.9997	other
Pseudodip-C12	other	0.00094	0.99906	other
Pseudodip-C13	other	0.00138	0.99862	other
Pseudodip-C14 (testset)	other	0.00249	0.99751	other
Pseudodip-C15	other	0.00611	0.99389	other
Pseudodip-C16-N (testset)	other	0.00177	0.99823	other
Pseudodip-C17 (testset)	other	0.00083	0.99917	other
Pseudodip-C18	other	0.00142	0.99858	other
Pseudodip-C19	other	1e-05	0.99999	other
Pseudodip-C1	other	0.00029	0.99971	other
Pseudodip-C2-N (testset)	other	0.0034	0.9966	other
Pseudodip-C3	other	0.00076	0.99924	other
Pseudodip-C4	other	0.00658	0.99342	other
Pseudodip-C5 (testset)	other	0.00328	0.99672	other
Pseudodip-C6	other	0.00151	0.99849	other
Pseudodip-C7 (testset)	other	0.00029	0.99971	other
Pseudodip-C8 (testset)	other	0.0143	0.9857	other
Pseudodip-C9	other	0.00075	0.99925	other
Pseudodip-R1-N	other	0.00104	0.99896	other
T-ALL-10	other	0.01711	0.98289	other
T-ALL-1	other	0.02124	0.97876	other
T-ALL-2	other	0.03109	0.96891	other
T-ALL-3	other	0.00098	0.99902	other
T-ALL-4 (testset)	other	0.0033	0.9967	other
T-ALL-5	other	0.01299	0.98701	other
T-ALL-6	other	0.09509	0.90491	other
T-ALL-7 (testset)	other	0.0363	0.9637	other
T-ALL-8	other	0.05753	0.94247	other
T-ALL-9 (testset)	other	0.00088	0.99912	other
T-ALL-2M1	other	0.01524	0.98476	other
T-ALL-C10	other	0.04837	0.95163	other
T-ALL-C11	other	0.00598	0.99402	other
T-ALL-C12	other	0.01332	0.98668	other
T-ALL-C13	other	0.01115	0.98885	other
T-ALL-C14	other	0.06518	0.93482	other
T-ALL-C15 (testset)	other	0.01684	0.98316	other
T-ALL-C16	other	7e-04	0.9993	other
T-ALL-C17	other	0.00114	0.99886	other
T-ALL-C18 (testset)	other	0.00373	0.99627	other
T-ALL-C19 (testset)	other	0.03292	0.96708	other
T-ALL-C1 (testset)	other	0.0021	0.9979	other
T-ALL-C20	other	0.03378	0.96622	other
T-ALL-C21	other	0.00422	0.99578	other
T-ALL-C22	other	0.01381	0.98619	other
T-ALL-C23	other	0.01455	0.98545	other
T-ALL-C24	other	0.00423	0.99577	other
T-ALL-C25	other	0.02531	0.97469	other
T-ALL-C26 (testset)	other	0.01963	0.98037	other
T-ALL-C2 (testset)	other	0.02823	0.97177	other
T-ALL-C3	other	0.00557	0.99443	other
T-ALL-C4 (testset)	other	0.00833	0.99167	other
T-ALL-C5 (testset)	other	0.00037	0.99963	other
T-ALL-C6 (testset)	other	0.01154	0.98846	other
T-ALL-C7	other	0.00137	0.99863	other
T-ALL-C8	other	0.04106	0.95894	other
T-ALL-C9	other	0.0142	0.9858	other
T-ALL-R1	other	0.03674	0.96326	other
T-ALL-R2	other	0.00025	0.99975	other
T-ALL-R3	other	0.0241	0.9759	other
T-ALL-R4	other	0.04821	0.95179	other
T-ALL-R5 (testset)	other	0.00146	0.99854	other
T-ALL-R6	other	0.00061	0.99939	other
TEL-AML1-10 (testset)	other	0.00015	0.99985	other
TEL-AML1-11	other	9e-04	0.9991	other
TEL-AML1-12 (testset)	other	0.00144	0.99856	other
TEL-AML1-13	other	6e-05	0.99994	other
TEL-AML1-14	other	0.00035	0.99965	other
TEL-AML1-1 (testset)	other	0.00116	0.99884	other
TEL-AML1-2	other	0.00129	0.99871	other
TEL-AML1-3 (testset)	other	0.00106	0.99894	other
TEL-AML1-4	other	3e-04	0.9997	other
TEL-AML1-5	other	0.01502	0.98498	other
TEL-AML1-6 (testset)	other	0.0365	0.9635	other
TEL-AML1-7 (testset)	other	0.00037	0.99963	other
TEL-AML1-8	other	0.00156	0.99844	other
TEL-AML1-9	other	0.0018	0.9982	other
TEL-AML1-2M1 (testset)	other	0.00142	0.99858	other
TEL-AML1-2M2	other	0.00089	0.99911	other
TEL-AML1-2M3	other	0.00181	0.99819	other
TEL-AML1-2M4 (testset)	other	0.00045	0.99955	other
TEL-AML1-2M5	other	0.00037	0.99963	other
TEL-AML1-C10 (testset)	other	3e-04	0.9997	other
TEL-AML1-C11	other	0.00028	0.99972	other
TEL-AML1-C12 (testset)	other	0.00155	0.99845	other
TEL-AML1-C13 (testset)	other	0.00046	0.99954	other
TEL-AML1-C14	other	0.00029	0.99971	other
TEL-AML1-C15	other	0.00017	0.99983	other
TEL-AML1-C16	other	0.00029	0.99971	other
TEL-AML1-C17 (testset)	other	0.00327	0.99673	other
TEL-AML1-C18 (testset)	other	0.00068	0.99932	other
TEL-AML1-C19	other	0.00047	0.99953	other
TEL-AML1-C1	other	0.00117	0.99883	other
TEL-AML1-C20	other	0.00027	0.99973	other
TEL-AML1-C21	other	4e-04	0.9996	other
TEL-AML1-C22	other	3e-05	0.99997	other
TEL-AML1-C23	other	0.00112	0.99888	other
TEL-AML1-C24	other	3e-05	0.99997	other
TEL-AML1-C25 (testset)	other	0.00315	0.99685	other
TEL-AML1-C26	other	0.00028	0.99972	other
TEL-AML1-C27 (testset)	other	0.00038	0.99962	other
TEL-AML1-C28	other	0.00029	0.99971	other
TEL-AML1-C29 (testset)	other	0.00084	0.99916	other
TEL-AML1-C2	other	0.00145	0.99855	other
TEL-AML1-C30	other	0.00053	0.99947	other
TEL-AML1-C31 (testset)	other	0.00016	0.99984	other
TEL-AML1-C32	other	0.00013	0.99987	other
TEL-AML1-C33	other	0.00042	0.99958	other
TEL-AML1-C34 (testset)	other	0.00019	0.99981	other
TEL-AML1-C35	other	7e-05	0.99993	other
TEL-AML1-C36	other	0.00126	0.99874	other
TEL-AML1-C37	other	0.00011	0.99989	other
TEL-AML1-C38 (testset)	other	0.00152	0.99848	other
TEL-AML1-C39	other	0.00026	0.99974	other
TEL-AML1-C3 (testset)	other	2e-04	0.9998	other
TEL-AML1-C40 (testset)	other	8e-04	0.9992	other
TEL-AML1-C41	other	0.00098	0.99902	other
TEL-AML1-C42 (testset)	other	0.00129	0.99871	other
TEL-AML1-C43	other	0.00246	0.99754	other
TEL-AML1-C44 (testset)	other	0.00111	0.99889	other
TEL-AML1-C45	other	0.0044	0.9956	other
TEL-AML1-C46 (testset)	other	3e-05	0.99997	other
TEL-AML1-C47	other	0.00022	0.99978	other
TEL-AML1-C48	other	4e-05	0.99996	other
TEL-AML1-C49	other	0.00032	0.99968	other
TEL-AML1-C4	other	0.00187	0.99813	other
TEL-AML1-C50	other	0.00032	0.99968	other
TEL-AML1-C51	other	0.00054	0.99946	other
TEL-AML1-C52	other	0.00192	0.99808	other
TEL-AML1-C53	other	0.00298	0.99702	other
TEL-AML1-C54	other	9e-05	0.99991	other
TEL-AML1-C55	other	0.00134	0.99866	other
TEL-AML1-C56	other	6e-05	0.99994	other
TEL-AML1-C57 (testset)	other	9e-05	0.99991	other
TEL-AML1-C5 (testset)	other	0.00023	0.99977	other
TEL-AML1-C6	other	7e-05	0.99993	other
TEL-AML1-C7	other	0.00015	0.99985	other
TEL-AML1-C8	other	0.00232	0.99768	other
TEL-AML1-C9 (testset)	other	0.00207	0.99793	other
TEL-AML1-R1	other	0.00217	0.99783	other
TEL-AML1-R2	other	0.00095	0.99905	other
TEL-AML1-R3 (testset)	other	0.00508	0.99492	other