GO:0007242


GO:0007242

intracellular signaling cascade
(annotated genes)

Biological
Process

Parent node

This leaf node contains 312 genes

The following 15 of these are used in classification:

 SymbolGenenameT-ALL scoreother score
2059_s_atLCK lymphocyte-specific protein tyrosine kinase1.844-0.2792
33238_atLCK lymphocyte-specific protein tyrosine kinase1.7478-0.2646
38147_atSH2D1A SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome)1.5022-0.2274
38949_atPRKCQ protein kinase C, theta0.9605-0.1454
38242_atBLNK B-cell linker-0.75930.115
38893_atNCF4 neutrophil cytosolic factor 4, 40kDa-0.56930.0862
1426_atSLA Src-like-adaptor0.4953-0.075
1085_s_atPLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)-0.3570.0541
38894_g_atNCF4 neutrophil cytosolic factor 4, 40kDa-0.34550.0523
39319_atLCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.189-0.0286
506_s_atSTAT5A signal transducer and activator of transcription 5A0.1436-0.0217
37180_atPLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)-0.12440.0188
31945_s_atSH2D1A SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome)0.1125-0.017
36139_atC6orf4 chromosome 6 open reading frame 4-0.11240.017
172_atINPP5D inositol polyphosphate-5-phosphatase, 145kDa-0.10640.0161

Performance on training data

 SensitivitySpecificity
T-ALL0.953491
other10.95349

Performance on test data

 SensitivitySpecificity
T-ALL0.953491
other10.95349

Predictions

 ClassT-ALLotherPredictionn
BCR-ABL-1 (testset)other1e-050.99999 other
BCR-ABL-2 (testset)other0.000260.99974 other
BCR-ABL-3 (testset)other01 other
BCR-ABL-4 (testset)other01 other
BCR-ABL-5 (testset)other1e-050.99999 other
BCR-ABL-6 (testset)other01 other
BCR-ABL-7 (testset)other0.001020.99898 other
BCR-ABL-8 (testset)other01 other
BCR-ABL-9 (testset)other01 other
BCR-ABL-C1 (testset)other4e-050.99996 other
BCR-ABL-Hyperdip-10 (testset)other01 other
BCR-ABL-Hyperdip-R5 (testset)other01 other
BCR-ABL-R1 (testset)other2e-050.99998 other
BCR-ABL-R2 (testset)other0.000180.99982 other
BCR-ABL-R3 (testset)other4e-050.99996 other
E2A-PBX1-10 (testset)other1e-050.99999 other
E2A-PBX1-11 (testset)other01 other
E2A-PBX1-12 (testset)other2e-050.99998 other
E2A-PBX1-13 (testset)other0.000110.99989 other
E2A-PBX1-1 (testset)other1e-050.99999 other
E2A-PBX1-2 (testset)other1e-050.99999 other
E2A-PBX1-3 (testset)other1e-050.99999 other
E2A-PBX1-4 (testset)other01 other
E2A-PBX1-5 (testset)other2e-050.99998 other
E2A-PBX1-6 (testset)other01 other
E2A-PBX1-7 (testset)other1e-050.99999 other
E2A-PBX1-8 (testset)other0.000150.99985 other
E2A-PBX1-9 (testset)other0.000140.99986 other
E2A-PBX1-2M1 (testset)other1e-050.99999 other
E2A-PBX1-C10 (testset)other0.000170.99983 other
E2A-PBX1-C11 (testset)other1e-050.99999 other
E2A-PBX1-C12 (testset)other3e-050.99997 other
E2A-PBX1-C1 (testset)other0.002410.99759 other
E2A-PBX1-C2 (testset)other0.000190.99981 other
E2A-PBX1-C3 (testset)other01 other
E2A-PBX1-C4 (testset)other3e-050.99997 other
E2A-PBX1-C5 (testset)other4e-050.99996 other
E2A-PBX1-C6 (testset)other01 other
E2A-PBX1-C7 (testset)other01 other
E2A-PBX1-C8 (testset)other0.006610.99339 other
E2A-PBX1-C9 (testset)other1e-050.99999 other
E2A-PBX1-R1 (testset)other01 other
Hyperdip-50-10 (testset)other6e-050.99994 other
Hyperdip-50-11 (testset)other0.012670.98733 other
Hyperdip-50-12 (testset)other6e-050.99994 other
Hyperdip-50-13 (testset)other1e-050.99999 other
Hyperdip-50-14 (testset)other01 other
Hyperdip-50-1 (testset)other01 other
Hyperdip-50-2 (testset)other01 other
Hyperdip-50-3 (testset)other01 other
Hyperdip-50-4 (testset)other0.06140.9386 other
Hyperdip-50-5 (testset)other01 other
Hyperdip-50-6 (testset)other01 other
Hyperdip-50-7 (testset)other01 other
Hyperdip-50-8 (testset)other01 other
Hyperdip-50-9 (testset)other01 other
Hyperdip-50-2M1 (testset)other2e-050.99998 other
Hyperdip-50-2M2 (testset)other2e-050.99998 other
Hyperdip-50-C10 (testset)other6e-050.99994 other
Hyperdip-50-C11 (testset)other1e-050.99999 other
Hyperdip-50-C12 (testset)other01 other
Hyperdip-50-C13 (testset)other01 other
Hyperdip-50-C14 (testset)other1e-050.99999 other
Hyperdip-50-C15 (testset)other1e-050.99999 other
Hyperdip-50-C16 (testset)other01 other
Hyperdip-50-C17 (testset)other1e-050.99999 other
Hyperdip-50-C18 (testset)other01 other
Hyperdip-50-C19 (testset)other01 other
Hyperdip-50-C1 (testset)other01 other
Hyperdip-50-C20 (testset)other1e-050.99999 other
Hyperdip-50-C21 (testset)other1e-050.99999 other
Hyperdip-50-C22 (testset)other01 other
Hyperdip-50-C23 (testset)other01 other
Hyperdip-50-C24 (testset)other9e-050.99991 other
Hyperdip-50-C25 (testset)other01 other
Hyperdip-50-C26 (testset)other01 other
Hyperdip-50-C27-N (testset)other2e-050.99998 other
Hyperdip-50-C28 (testset)other01 other
Hyperdip-50-C29 (testset)other2e-050.99998 other
Hyperdip-50-C2 (testset)other0.000880.99912 other
Hyperdip-50-C30 (testset)other01 other
Hyperdip-50-C31 (testset)other01 other
Hyperdip-50-C32 (testset)other01 other
Hyperdip-50-C33 (testset)other01 other
Hyperdip-50-C34 (testset)other1e-050.99999 other
Hyperdip-50-C35 (testset)other6e-050.99994 other
Hyperdip-50-C36 (testset)other01 other
Hyperdip-50-C37 (testset)other01 other
Hyperdip-50-C38 (testset)other01 other
Hyperdip-50-C39 (testset)other01 other
Hyperdip-50-C3 (testset)other01 other
Hyperdip-50-C40 (testset)other1e-050.99999 other
Hyperdip-50-C41 (testset)other01 other
Hyperdip-50-C42 (testset)other01 other
Hyperdip-50-C43 (testset)other1e-050.99999 other
Hyperdip-50-C4 (testset)other1e-050.99999 other
Hyperdip-50-C5 (testset)other0.002090.99791 other
Hyperdip-50-C6 (testset)other01 other
Hyperdip-50-C7 (testset)other01 other
Hyperdip-50-C8 (testset)other01 other
Hyperdip-50-C9 (testset)other01 other
Hyperdip-50-R1 (testset)other2e-050.99998 other
Hyperdip-50-R2 (testset)other01 other
Hyperdip-50-R3 (testset)other6e-050.99994 other
Hyperdip-50-R4 (testset)other01 other
Hyperdip-50-R5 (testset)other01 other
Hyperdip47-50-1 (testset)other1e-050.99999 other
Hyperdip47-50-2 (testset)other01 other
Hyperdip47-50-3 (testset)other0.221260.77874 other
Hyperdip47-50-2M1 (testset)other01 other
Hyperdip47-50-C10 (testset)other3e-050.99997 other
Hyperdip47-50-C11 (testset)other5e-050.99995 other
Hyperdip47-50-C12 (testset)other0.000120.99988 other
Hyperdip47-50-C13 (testset)other4e-050.99996 other
Hyperdip47-50-C14-N (testset)other01 other
Hyperdip47-50-C15 (testset)other01 other
Hyperdip47-50-C16 (testset)other01 other
Hyperdip47-50-C17 (testset)other1e-050.99999 other
Hyperdip47-50-C18 (testset)other01 other
Hyperdip47-50-C19 (testset)other0.001990.99801 other
Hyperdip47-50-C1 (testset)other01 other
Hyperdip47-50-C2 (testset)other0.000310.99969 other
Hyperdip47-50-C3-N (testset)other01 other
Hyperdip47-50-C4 (testset)other2e-050.99998 other
Hyperdip47-50-C5 (testset)other0.012640.98736 other
Hyperdip47-50-C6 (testset)other0.000120.99988 other
Hyperdip47-50-C7 (testset)other2e-050.99998 other
Hyperdip47-50-C8 (testset)other2e-050.99998 other
Hyperdip47-50-C9 (testset)other01 other
Hypodip-1 (testset)other5e-050.99995 other
Hypodip-2 (testset)other0.004490.99551 other
Hypodip-2M1 (testset)other0.00110.9989 other
Hypodip-C1 (testset)other4e-050.99996 other
Hypodip-C2 (testset)other1e-050.99999 other
Hypodip-C3 (testset)other01 other
Hypodip-C4 (testset)other01 other
Hypodip-C5 (testset)other1e-050.99999 other
Hypodip-C6 (testset)other01 other
MLL-1 (testset)other2e-050.99998 other
MLL-2 (testset)other01 other
MLL-3 (testset)other01 other
MLL-4 (testset)other01 other
MLL-5 (testset)other01 other
MLL-6 (testset)other01 other
MLL-7 (testset)other01 other
MLL-8 (testset)other01 other
MLL-2M1 (testset)other9e-050.99991 other
MLL-2M2 (testset)other01 other
MLL-C1 (testset)other01 other
MLL-C2 (testset)other01 other
MLL-C3 (testset)other0.010160.98984 other
MLL-C4 (testset)other01 other
MLL-C5 (testset)other0.032060.96794 other
MLL-C6 (testset)other0.000320.99968 other
MLL-R1 (testset)other6e-050.99994 other
MLL-R2 (testset)other01 other
MLL-R3 (testset)other01 other
MLL-R4 (testset)other1e-050.99999 other
Normal-1 (testset)other1e-050.99999 other
Normal-2 (testset)other01 other
Normal-3 (testset)other1e-050.99999 other
Normal-C1-N (testset)other5e-050.99995 other
Normal-C10 (testset)other01 other
Normal-C11-N (testset)other1e-050.99999 other
Normal-C12 (testset)other6e-050.99994 other
Normal-C2-N (testset)other01 other
Normal-C3-N (testset)other1e-050.99999 other
Normal-C4-N (testset)other1e-050.99999 other
Normal-C5 (testset)other0.000150.99985 other
Normal-C6 (testset)other4e-050.99996 other
Normal-C7-N (testset)other7e-050.99993 other
Normal-C8 (testset)other01 other
Normal-C9 (testset)other2e-050.99998 other
Normal-R1 (testset)other1e-050.99999 other
Normal-R2-N (testset)other1e-050.99999 other
Normal-R3 (testset)other5e-050.99995 other
Pseudodip-1 (testset)other1e-050.99999 other
Pseudodip-2 (testset)other0.014180.98582 other
Pseudodip-3 (testset)other3e-050.99997 other
Pseudodip-4 (testset)other01 other
Pseudodip-5 (testset)other01 other
Pseudodip-6 (testset)other01 other
Pseudodip-7 (testset)other1e-050.99999 other
Pseudodip-8-N (testset)other01 other
Pseudodip-9 (testset)other9e-050.99991 other
Pseudodip-C10 (testset)other0.000170.99983 other
Pseudodip-C11 (testset)other1e-050.99999 other
Pseudodip-C12 (testset)other0.000860.99914 other
Pseudodip-C13 (testset)other01 other
Pseudodip-C14 (testset)other2e-050.99998 other
Pseudodip-C15 (testset)other2e-050.99998 other
Pseudodip-C16-N (testset)other0.000540.99946 other
Pseudodip-C17 (testset)other1e-050.99999 other
Pseudodip-C18 (testset)other01 other
Pseudodip-C19 (testset)other01 other
Pseudodip-C1 (testset)other4e-050.99996 other
Pseudodip-C2-N (testset)other7e-050.99993 other
Pseudodip-C3 (testset)other1e-050.99999 other
Pseudodip-C4 (testset)other0.000110.99989 other
Pseudodip-C5 (testset)other1e-050.99999 other
Pseudodip-C6 (testset)other7e-050.99993 other
Pseudodip-C7 (testset)other01 other
Pseudodip-C8 (testset)other01 other
Pseudodip-C9 (testset)other01 other
Pseudodip-R1-N (testset)other01 other
T-ALL-10 (testset)T-ALL10 T-ALL
T-ALL-1 (testset)T-ALL10 T-ALL
T-ALL-2 (testset)T-ALL0.050890.94911 other
T-ALL-3 (testset)T-ALL10 T-ALL
T-ALL-4 (testset)T-ALL10 T-ALL
T-ALL-5 (testset)T-ALL10 T-ALL
T-ALL-6 (testset)T-ALL10 T-ALL
T-ALL-7 (testset)T-ALL10 T-ALL
T-ALL-8 (testset)T-ALL10 T-ALL
T-ALL-9 (testset)T-ALL10 T-ALL
T-ALL-2M1 (testset)T-ALL10 T-ALL
T-ALL-C10 (testset)T-ALL10 T-ALL
T-ALL-C11 (testset)T-ALL10 T-ALL
T-ALL-C12 (testset)T-ALL10 T-ALL
T-ALL-C13 (testset)T-ALL10 T-ALL
T-ALL-C14 (testset)T-ALL0.997920.00208 T-ALL
T-ALL-C15 (testset)T-ALL10 T-ALL
T-ALL-C16 (testset)T-ALL0.995920.00408 T-ALL
T-ALL-C17 (testset)T-ALL0.906990.09301 T-ALL
T-ALL-C18 (testset)T-ALL0.98320.0168 T-ALL
T-ALL-C19 (testset)T-ALL10 T-ALL
T-ALL-C1 (testset)T-ALL0.997050.00295 T-ALL
T-ALL-C20 (testset)T-ALL10 T-ALL
T-ALL-C21 (testset)T-ALL10 T-ALL
T-ALL-C22 (testset)T-ALL10 T-ALL
T-ALL-C23 (testset)T-ALL0.940120.05988 T-ALL
T-ALL-C24 (testset)T-ALL10 T-ALL
T-ALL-C25 (testset)T-ALL10 T-ALL
T-ALL-C26 (testset)T-ALL10 T-ALL
T-ALL-C2 (testset)T-ALL10 T-ALL
T-ALL-C3 (testset)T-ALL10 T-ALL
T-ALL-C4 (testset)T-ALL0.999991e-05 T-ALL
T-ALL-C5 (testset)T-ALL0.00310.9969 other
T-ALL-C6 (testset)T-ALL10 T-ALL
T-ALL-C7 (testset)T-ALL10 T-ALL
T-ALL-C8 (testset)T-ALL0.999310.00069 T-ALL
T-ALL-C9 (testset)T-ALL10 T-ALL
T-ALL-R1 (testset)T-ALL10 T-ALL
T-ALL-R2 (testset)T-ALL10 T-ALL
T-ALL-R3 (testset)T-ALL10 T-ALL
T-ALL-R4 (testset)T-ALL10 T-ALL
T-ALL-R5 (testset)T-ALL0.999982e-05 T-ALL
T-ALL-R6 (testset)T-ALL0.999240.00076 T-ALL
TEL-AML1-10 (testset)other01 other
TEL-AML1-11 (testset)other01 other
TEL-AML1-12 (testset)other0.000610.99939 other
TEL-AML1-13 (testset)other2e-050.99998 other
TEL-AML1-14 (testset)other2e-050.99998 other
TEL-AML1-1 (testset)other9e-050.99991 other
TEL-AML1-2 (testset)other0.000440.99956 other
TEL-AML1-3 (testset)other0.000880.99912 other
TEL-AML1-4 (testset)other1e-050.99999 other
TEL-AML1-5 (testset)other1e-040.9999 other
TEL-AML1-6 (testset)other1e-050.99999 other
TEL-AML1-7 (testset)other01 other
TEL-AML1-8 (testset)other3e-050.99997 other
TEL-AML1-9 (testset)other8e-050.99992 other
TEL-AML1-2M1 (testset)other2e-050.99998 other
TEL-AML1-2M2 (testset)other4e-050.99996 other
TEL-AML1-2M3 (testset)other2e-050.99998 other
TEL-AML1-2M4 (testset)other0.000560.99944 other
TEL-AML1-2M5 (testset)other4e-050.99996 other
TEL-AML1-C10 (testset)other0.000130.99987 other
TEL-AML1-C11 (testset)other3e-050.99997 other
TEL-AML1-C12 (testset)other1e-050.99999 other
TEL-AML1-C13 (testset)other01 other
TEL-AML1-C14 (testset)other3e-050.99997 other
TEL-AML1-C15 (testset)other1e-050.99999 other
TEL-AML1-C16 (testset)other01 other
TEL-AML1-C17 (testset)other1e-040.9999 other
TEL-AML1-C18 (testset)other4e-050.99996 other
TEL-AML1-C19 (testset)other1e-050.99999 other
TEL-AML1-C1 (testset)other5e-050.99995 other
TEL-AML1-C20 (testset)other1e-050.99999 other
TEL-AML1-C21 (testset)other0.000390.99961 other
TEL-AML1-C22 (testset)other0.0290.971 other
TEL-AML1-C23 (testset)other1e-050.99999 other
TEL-AML1-C24 (testset)other3e-050.99997 other
TEL-AML1-C25 (testset)other0.000380.99962 other
TEL-AML1-C26 (testset)other2e-050.99998 other
TEL-AML1-C27 (testset)other2e-050.99998 other
TEL-AML1-C28 (testset)other5e-050.99995 other
TEL-AML1-C29 (testset)other1e-050.99999 other
TEL-AML1-C2 (testset)other0.000240.99976 other
TEL-AML1-C30 (testset)other4e-050.99996 other
TEL-AML1-C31 (testset)other01 other
TEL-AML1-C32 (testset)other0.000430.99957 other
TEL-AML1-C33 (testset)other01 other
TEL-AML1-C34 (testset)other1e-050.99999 other
TEL-AML1-C35 (testset)other6e-050.99994 other
TEL-AML1-C36 (testset)other3e-050.99997 other
TEL-AML1-C37 (testset)other1e-050.99999 other
TEL-AML1-C38 (testset)other1e-050.99999 other
TEL-AML1-C39 (testset)other1e-050.99999 other
TEL-AML1-C3 (testset)other3e-050.99997 other
TEL-AML1-C40 (testset)other4e-050.99996 other
TEL-AML1-C41 (testset)other0.0010.999 other
TEL-AML1-C42 (testset)other0.001150.99885 other
TEL-AML1-C43 (testset)other1e-050.99999 other
TEL-AML1-C44 (testset)other3e-050.99997 other
TEL-AML1-C45 (testset)other2e-050.99998 other
TEL-AML1-C46 (testset)other0.001330.99867 other
TEL-AML1-C47 (testset)other01 other
TEL-AML1-C48 (testset)other0.033510.96649 other
TEL-AML1-C49 (testset)other5e-050.99995 other
TEL-AML1-C4 (testset)other9e-050.99991 other
TEL-AML1-C50 (testset)other9e-050.99991 other
TEL-AML1-C51 (testset)other4e-050.99996 other
TEL-AML1-C52 (testset)other0.000350.99965 other
TEL-AML1-C53 (testset)other0.116410.88359 other
TEL-AML1-C54 (testset)other01 other
TEL-AML1-C55 (testset)other4e-050.99996 other
TEL-AML1-C56 (testset)other6e-050.99994 other
TEL-AML1-C57 (testset)other0.000110.99989 other
TEL-AML1-C5 (testset)other6e-050.99994 other
TEL-AML1-C6 (testset)other01 other
TEL-AML1-C7 (testset)other0.000530.99947 other
TEL-AML1-C8 (testset)other0.001620.99838 other
TEL-AML1-C9 (testset)other0.002460.99754 other
TEL-AML1-R1 (testset)other8e-050.99992 other
TEL-AML1-R2 (testset)other1e-040.9999 other
TEL-AML1-R3 (testset)other3e-050.99997 other

 


Generated by StAM on Tue Sep 7 18:40:10 2004