GO:0007169


GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway
(annotated genes)

Biological
Process

Parent node

This leaf node contains 84 genes

The following 15 of these are used in classification:

 SymbolGenenameT-ALL scoreother score
771_s_atCD7 CD7 antigen (p41)1.3533-0.2049
39930_atEPHB6 EphB61.0891-0.1649
39319_atLCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)1.0784-0.1633
40699_atCD8A CD8 antigen, alpha polypeptide (p32)0.7957-0.1205
33162_atINSR insulin receptor-0.57010.0863
1988_atPDGFRA platelet-derived growth factor receptor, alpha polypeptide-0.46830.0709
1007_s_atDDR1 discoidin domain receptor family, member 1-0.32260.0488
36643_atDDR1 discoidin domain receptor family, member 1-0.28110.0426
1351_atEPHB4 EphB4-0.25350.0384
1572_s_atINSR insulin receptor-0.09590.0145
34433_atDOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)0.0674-0.0102
39309_atBDKRB2 bradykinin receptor B20.0639-0.0097
32888_atLTK leukocyte tyrosine kinase-0.04890.0074
816_g_atDOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)0.0478-0.0072
37363_atMTSS1 metastasis suppressor 1-0.03630.0055

Performance on training data

 SensitivitySpecificity
T-ALL0.860471
other10.86047

Performance on test data

 SensitivitySpecificity
T-ALL0.860471
other10.86047

Predictions

 ClassT-ALLotherPredictionn
BCR-ABL-1 (testset)other0.078010.92199 other
BCR-ABL-2 (testset)other0.016210.98379 other
BCR-ABL-3 (testset)other0.008860.99114 other
BCR-ABL-4 (testset)other0.002380.99762 other
BCR-ABL-5 (testset)other0.004980.99502 other
BCR-ABL-6 (testset)other0.0130.987 other
BCR-ABL-7 (testset)other0.010320.98968 other
BCR-ABL-8 (testset)other0.000820.99918 other
BCR-ABL-9 (testset)other0.001960.99804 other
BCR-ABL-C1 (testset)other0.000930.99907 other
BCR-ABL-Hyperdip-10 (testset)other0.00470.9953 other
BCR-ABL-Hyperdip-R5 (testset)other0.003570.99643 other
BCR-ABL-R1 (testset)other0.003970.99603 other
BCR-ABL-R2 (testset)other0.037260.96274 other
BCR-ABL-R3 (testset)other0.037540.96246 other
E2A-PBX1-10 (testset)other0.000250.99975 other
E2A-PBX1-11 (testset)other0.001760.99824 other
E2A-PBX1-12 (testset)other0.002340.99766 other
E2A-PBX1-13 (testset)other0.002060.99794 other
E2A-PBX1-1 (testset)other0.003960.99604 other
E2A-PBX1-2 (testset)other0.002260.99774 other
E2A-PBX1-3 (testset)other0.001320.99868 other
E2A-PBX1-4 (testset)other0.000560.99944 other
E2A-PBX1-5 (testset)other5e-040.9995 other
E2A-PBX1-6 (testset)other9e-040.9991 other
E2A-PBX1-7 (testset)other0.002770.99723 other
E2A-PBX1-8 (testset)other0.000580.99942 other
E2A-PBX1-9 (testset)other0.000220.99978 other
E2A-PBX1-2M1 (testset)other0.006560.99344 other
E2A-PBX1-C10 (testset)other0.003420.99658 other
E2A-PBX1-C11 (testset)other0.000610.99939 other
E2A-PBX1-C12 (testset)other0.002480.99752 other
E2A-PBX1-C1 (testset)other0.02860.9714 other
E2A-PBX1-C2 (testset)other0.002020.99798 other
E2A-PBX1-C3 (testset)other0.000340.99966 other
E2A-PBX1-C4 (testset)other0.001080.99892 other
E2A-PBX1-C5 (testset)other0.001090.99891 other
E2A-PBX1-C6 (testset)other0.001570.99843 other
E2A-PBX1-C7 (testset)other0.000380.99962 other
E2A-PBX1-C8 (testset)other0.046390.95361 other
E2A-PBX1-C9 (testset)other0.001140.99886 other
E2A-PBX1-R1 (testset)other0.003360.99664 other
Hyperdip-50-10 (testset)other0.032190.96781 other
Hyperdip-50-11 (testset)other0.151360.84864 other
Hyperdip-50-12 (testset)other0.004190.99581 other
Hyperdip-50-13 (testset)other0.003570.99643 other
Hyperdip-50-14 (testset)other0.000280.99972 other
Hyperdip-50-1 (testset)other0.001510.99849 other
Hyperdip-50-2 (testset)other0.001980.99802 other
Hyperdip-50-3 (testset)other0.003230.99677 other
Hyperdip-50-4 (testset)other0.078390.92161 other
Hyperdip-50-5 (testset)other0.001140.99886 other
Hyperdip-50-6 (testset)other0.001610.99839 other
Hyperdip-50-7 (testset)other0.001390.99861 other
Hyperdip-50-8 (testset)other6e-040.9994 other
Hyperdip-50-9 (testset)other0.006030.99397 other
Hyperdip-50-2M1 (testset)other0.013120.98688 other
Hyperdip-50-2M2 (testset)other0.007210.99279 other
Hyperdip-50-C10 (testset)other0.001370.99863 other
Hyperdip-50-C11 (testset)other2e-040.9998 other
Hyperdip-50-C12 (testset)other0.013160.98684 other
Hyperdip-50-C13 (testset)other0.005070.99493 other
Hyperdip-50-C14 (testset)other0.002850.99715 other
Hyperdip-50-C15 (testset)other0.001730.99827 other
Hyperdip-50-C16 (testset)other0.010770.98923 other
Hyperdip-50-C17 (testset)other0.002330.99767 other
Hyperdip-50-C18 (testset)other0.000410.99959 other
Hyperdip-50-C19 (testset)other0.003480.99652 other
Hyperdip-50-C1 (testset)other0.001470.99853 other
Hyperdip-50-C20 (testset)other0.003880.99612 other
Hyperdip-50-C21 (testset)other0.001140.99886 other
Hyperdip-50-C22 (testset)other0.000730.99927 other
Hyperdip-50-C23 (testset)other0.000940.99906 other
Hyperdip-50-C24 (testset)other0.016860.98314 other
Hyperdip-50-C25 (testset)other0.000430.99957 other
Hyperdip-50-C26 (testset)other0.001450.99855 other
Hyperdip-50-C27-N (testset)other0.004290.99571 other
Hyperdip-50-C28 (testset)other0.003150.99685 other
Hyperdip-50-C29 (testset)other0.001750.99825 other
Hyperdip-50-C2 (testset)other0.02230.9777 other
Hyperdip-50-C30 (testset)other0.004270.99573 other
Hyperdip-50-C31 (testset)other0.00250.9975 other
Hyperdip-50-C32 (testset)other0.001550.99845 other
Hyperdip-50-C33 (testset)other0.001990.99801 other
Hyperdip-50-C34 (testset)other0.004960.99504 other
Hyperdip-50-C35 (testset)other0.011970.98803 other
Hyperdip-50-C36 (testset)other0.003750.99625 other
Hyperdip-50-C37 (testset)other0.003070.99693 other
Hyperdip-50-C38 (testset)other0.001120.99888 other
Hyperdip-50-C39 (testset)other0.004370.99563 other
Hyperdip-50-C3 (testset)other0.001210.99879 other
Hyperdip-50-C40 (testset)other0.004610.99539 other
Hyperdip-50-C41 (testset)other0.009840.99016 other
Hyperdip-50-C42 (testset)other0.007390.99261 other
Hyperdip-50-C43 (testset)other0.003460.99654 other
Hyperdip-50-C4 (testset)other0.00170.9983 other
Hyperdip-50-C5 (testset)other0.01650.9835 other
Hyperdip-50-C6 (testset)other0.000670.99933 other
Hyperdip-50-C7 (testset)other0.002950.99705 other
Hyperdip-50-C8 (testset)other0.001220.99878 other
Hyperdip-50-C9 (testset)other0.002250.99775 other
Hyperdip-50-R1 (testset)other0.040750.95925 other
Hyperdip-50-R2 (testset)other0.000870.99913 other
Hyperdip-50-R3 (testset)other0.004530.99547 other
Hyperdip-50-R4 (testset)other0.009180.99082 other
Hyperdip-50-R5 (testset)other0.003170.99683 other
Hyperdip47-50-1 (testset)other0.001530.99847 other
Hyperdip47-50-2 (testset)other0.005890.99411 other
Hyperdip47-50-3 (testset)other0.000930.99907 other
Hyperdip47-50-2M1 (testset)other0.001410.99859 other
Hyperdip47-50-C10 (testset)other0.003030.99697 other
Hyperdip47-50-C11 (testset)other0.016320.98368 other
Hyperdip47-50-C12 (testset)other0.003230.99677 other
Hyperdip47-50-C13 (testset)other0.002020.99798 other
Hyperdip47-50-C14-N (testset)other0.000720.99928 other
Hyperdip47-50-C15 (testset)other0.007430.99257 other
Hyperdip47-50-C16 (testset)other0.000250.99975 other
Hyperdip47-50-C17 (testset)other0.007330.99267 other
Hyperdip47-50-C18 (testset)other0.001090.99891 other
Hyperdip47-50-C19 (testset)other0.014990.98501 other
Hyperdip47-50-C1 (testset)other0.001520.99848 other
Hyperdip47-50-C2 (testset)other0.021890.97811 other
Hyperdip47-50-C3-N (testset)other0.000570.99943 other
Hyperdip47-50-C4 (testset)other0.001070.99893 other
Hyperdip47-50-C5 (testset)other0.000550.99945 other
Hyperdip47-50-C6 (testset)other0.001620.99838 other
Hyperdip47-50-C7 (testset)other0.014680.98532 other
Hyperdip47-50-C8 (testset)other0.013730.98627 other
Hyperdip47-50-C9 (testset)other0.000580.99942 other
Hypodip-1 (testset)other0.000950.99905 other
Hypodip-2 (testset)other0.014810.98519 other
Hypodip-2M1 (testset)other0.039330.96067 other
Hypodip-C1 (testset)other0.001250.99875 other
Hypodip-C2 (testset)other0.004580.99542 other
Hypodip-C3 (testset)other0.00190.9981 other
Hypodip-C4 (testset)other0.005140.99486 other
Hypodip-C5 (testset)other0.002340.99766 other
Hypodip-C6 (testset)other0.001790.99821 other
MLL-1 (testset)other0.002280.99772 other
MLL-2 (testset)other0.003620.99638 other
MLL-3 (testset)other0.000630.99937 other
MLL-4 (testset)other0.003050.99695 other
MLL-5 (testset)other0.000740.99926 other
MLL-6 (testset)other0.011060.98894 other
MLL-7 (testset)other0.001230.99877 other
MLL-8 (testset)other0.000970.99903 other
MLL-2M1 (testset)other0.002390.99761 other
MLL-2M2 (testset)other0.000510.99949 other
MLL-C1 (testset)other0.000520.99948 other
MLL-C2 (testset)other0.004720.99528 other
MLL-C3 (testset)other9e-040.9991 other
MLL-C4 (testset)other0.001840.99816 other
MLL-C5 (testset)other0.001430.99857 other
MLL-C6 (testset)other0.002110.99789 other
MLL-R1 (testset)other0.019810.98019 other
MLL-R2 (testset)other0.000850.99915 other
MLL-R3 (testset)other0.006280.99372 other
MLL-R4 (testset)other0.003880.99612 other
Normal-1 (testset)other0.005990.99401 other
Normal-2 (testset)other0.006520.99348 other
Normal-3 (testset)other0.001440.99856 other
Normal-C1-N (testset)other0.003990.99601 other
Normal-C10 (testset)other0.002870.99713 other
Normal-C11-N (testset)other0.005390.99461 other
Normal-C12 (testset)other0.014670.98533 other
Normal-C2-N (testset)other0.001450.99855 other
Normal-C3-N (testset)other0.003130.99687 other
Normal-C4-N (testset)other0.001520.99848 other
Normal-C5 (testset)other0.038220.96178 other
Normal-C6 (testset)other0.000480.99952 other
Normal-C7-N (testset)other0.001470.99853 other
Normal-C8 (testset)other0.00210.9979 other
Normal-C9 (testset)other0.000890.99911 other
Normal-R1 (testset)other0.004910.99509 other
Normal-R2-N (testset)other0.00380.9962 other
Normal-R3 (testset)other0.002720.99728 other
Pseudodip-1 (testset)other0.001170.99883 other
Pseudodip-2 (testset)other0.020640.97936 other
Pseudodip-3 (testset)other0.003040.99696 other
Pseudodip-4 (testset)other0.011860.98814 other
Pseudodip-5 (testset)other0.002940.99706 other
Pseudodip-6 (testset)other0.000810.99919 other
Pseudodip-7 (testset)other0.002120.99788 other
Pseudodip-8-N (testset)other1e-050.99999 other
Pseudodip-9 (testset)other0.025560.97444 other
Pseudodip-C10 (testset)other0.00140.9986 other
Pseudodip-C11 (testset)other0.001310.99869 other
Pseudodip-C12 (testset)other0.003950.99605 other
Pseudodip-C13 (testset)other0.002170.99783 other
Pseudodip-C14 (testset)other0.003530.99647 other
Pseudodip-C15 (testset)other0.002230.99777 other
Pseudodip-C16-N (testset)other0.037340.96266 other
Pseudodip-C17 (testset)other0.002120.99788 other
Pseudodip-C18 (testset)other0.017580.98242 other
Pseudodip-C19 (testset)other0.005870.99413 other
Pseudodip-C1 (testset)other0.014010.98599 other
Pseudodip-C2-N (testset)other0.001140.99886 other
Pseudodip-C3 (testset)other0.000550.99945 other
Pseudodip-C4 (testset)other0.003890.99611 other
Pseudodip-C5 (testset)other0.000730.99927 other
Pseudodip-C6 (testset)other0.007330.99267 other
Pseudodip-C7 (testset)other0.000740.99926 other
Pseudodip-C8 (testset)other0.000680.99932 other
Pseudodip-C9 (testset)other0.000790.99921 other
Pseudodip-R1-N (testset)other0.000530.99947 other
T-ALL-10 (testset)T-ALL0.954570.04543 T-ALL
T-ALL-1 (testset)T-ALL0.877670.12233 T-ALL
T-ALL-2 (testset)T-ALL0.008040.99196 other
T-ALL-3 (testset)T-ALL0.999982e-05 T-ALL
T-ALL-4 (testset)T-ALL0.993750.00625 T-ALL
T-ALL-5 (testset)T-ALL0.996270.00373 T-ALL
T-ALL-6 (testset)T-ALL0.84780.1522 T-ALL
T-ALL-7 (testset)T-ALL0.999480.00052 T-ALL
T-ALL-8 (testset)T-ALL0.985820.01418 T-ALL
T-ALL-9 (testset)T-ALL0.971290.02871 T-ALL
T-ALL-2M1 (testset)T-ALL10 T-ALL
T-ALL-C10 (testset)T-ALL0.998960.00104 T-ALL
T-ALL-C11 (testset)T-ALL0.994430.00557 T-ALL
T-ALL-C12 (testset)T-ALL0.999955e-05 T-ALL
T-ALL-C13 (testset)T-ALL0.934920.06508 T-ALL
T-ALL-C14 (testset)T-ALL0.123780.87622 other
T-ALL-C15 (testset)T-ALL0.997390.00261 T-ALL
T-ALL-C16 (testset)T-ALL0.41690.5831 other
T-ALL-C17 (testset)T-ALL0.993990.00601 T-ALL
T-ALL-C18 (testset)T-ALL0.99946e-04 T-ALL
T-ALL-C19 (testset)T-ALL0.994180.00582 T-ALL
T-ALL-C1 (testset)T-ALL0.644760.35524 T-ALL
T-ALL-C20 (testset)T-ALL0.99440.0056 T-ALL
T-ALL-C21 (testset)T-ALL0.999850.00015 T-ALL
T-ALL-C22 (testset)T-ALL0.816850.18315 T-ALL
T-ALL-C23 (testset)T-ALL0.724950.27505 T-ALL
T-ALL-C24 (testset)T-ALL0.899380.10062 T-ALL
T-ALL-C25 (testset)T-ALL0.978470.02153 T-ALL
T-ALL-C26 (testset)T-ALL0.40230.5977 other
T-ALL-C2 (testset)T-ALL0.986950.01305 T-ALL
T-ALL-C3 (testset)T-ALL0.986770.01323 T-ALL
T-ALL-C4 (testset)T-ALL0.799260.20074 T-ALL
T-ALL-C5 (testset)T-ALL0.373580.62642 other
T-ALL-C6 (testset)T-ALL0.982260.01774 T-ALL
T-ALL-C7 (testset)T-ALL0.999710.00029 T-ALL
T-ALL-C8 (testset)T-ALL0.079740.92026 other
T-ALL-C9 (testset)T-ALL0.766840.23316 T-ALL
T-ALL-R1 (testset)T-ALL0.92710.0729 T-ALL
T-ALL-R2 (testset)T-ALL0.999964e-05 T-ALL
T-ALL-R3 (testset)T-ALL0.988310.01169 T-ALL
T-ALL-R4 (testset)T-ALL0.994340.00566 T-ALL
T-ALL-R5 (testset)T-ALL0.9980.002 T-ALL
T-ALL-R6 (testset)T-ALL0.574620.42538 T-ALL
TEL-AML1-10 (testset)other0.009240.99076 other
TEL-AML1-11 (testset)other0.003820.99618 other
TEL-AML1-12 (testset)other0.004020.99598 other
TEL-AML1-13 (testset)other0.000610.99939 other
TEL-AML1-14 (testset)other0.002420.99758 other
TEL-AML1-1 (testset)other0.002550.99745 other
TEL-AML1-2 (testset)other0.004570.99543 other
TEL-AML1-3 (testset)other0.010.99 other
TEL-AML1-4 (testset)other0.003540.99646 other
TEL-AML1-5 (testset)other0.017550.98245 other
TEL-AML1-6 (testset)other0.001170.99883 other
TEL-AML1-7 (testset)other0.000610.99939 other
TEL-AML1-8 (testset)other0.002360.99764 other
TEL-AML1-9 (testset)other0.005490.99451 other
TEL-AML1-2M1 (testset)other0.005140.99486 other
TEL-AML1-2M2 (testset)other0.000910.99909 other
TEL-AML1-2M3 (testset)other6e-040.9994 other
TEL-AML1-2M4 (testset)other0.00420.9958 other
TEL-AML1-2M5 (testset)other0.000780.99922 other
TEL-AML1-C10 (testset)other0.003950.99605 other
TEL-AML1-C11 (testset)other0.001670.99833 other
TEL-AML1-C12 (testset)other0.001160.99884 other
TEL-AML1-C13 (testset)other0.01090.9891 other
TEL-AML1-C14 (testset)other0.002340.99766 other
TEL-AML1-C15 (testset)other0.003830.99617 other
TEL-AML1-C16 (testset)other5e-040.9995 other
TEL-AML1-C17 (testset)other0.001510.99849 other
TEL-AML1-C18 (testset)other0.001110.99889 other
TEL-AML1-C19 (testset)other0.000220.99978 other
TEL-AML1-C1 (testset)other0.013460.98654 other
TEL-AML1-C20 (testset)other0.000310.99969 other
TEL-AML1-C21 (testset)other0.001330.99867 other
TEL-AML1-C22 (testset)other0.000370.99963 other
TEL-AML1-C23 (testset)other0.006450.99355 other
TEL-AML1-C24 (testset)other0.014050.98595 other
TEL-AML1-C25 (testset)other0.003750.99625 other
TEL-AML1-C26 (testset)other0.000310.99969 other
TEL-AML1-C27 (testset)other0.000380.99962 other
TEL-AML1-C28 (testset)other0.005430.99457 other
TEL-AML1-C29 (testset)other0.002170.99783 other
TEL-AML1-C2 (testset)other0.000310.99969 other
TEL-AML1-C30 (testset)other0.015140.98486 other
TEL-AML1-C31 (testset)other0.000330.99967 other
TEL-AML1-C32 (testset)other0.001420.99858 other
TEL-AML1-C33 (testset)other0.000640.99936 other
TEL-AML1-C34 (testset)other0.001250.99875 other
TEL-AML1-C35 (testset)other0.002670.99733 other
TEL-AML1-C36 (testset)other0.003050.99695 other
TEL-AML1-C37 (testset)other0.000470.99953 other
TEL-AML1-C38 (testset)other0.026680.97332 other
TEL-AML1-C39 (testset)other0.00260.9974 other
TEL-AML1-C3 (testset)other0.000280.99972 other
TEL-AML1-C40 (testset)other0.002840.99716 other
TEL-AML1-C41 (testset)other0.007760.99224 other
TEL-AML1-C42 (testset)other0.01150.9885 other
TEL-AML1-C43 (testset)other0.004490.99551 other
TEL-AML1-C44 (testset)other0.000460.99954 other
TEL-AML1-C45 (testset)other0.001430.99857 other
TEL-AML1-C46 (testset)other0.000410.99959 other
TEL-AML1-C47 (testset)other0.00210.9979 other
TEL-AML1-C48 (testset)other0.047650.95235 other
TEL-AML1-C49 (testset)other0.001960.99804 other
TEL-AML1-C4 (testset)other0.002040.99796 other
TEL-AML1-C50 (testset)other0.003090.99691 other
TEL-AML1-C51 (testset)other0.001980.99802 other
TEL-AML1-C52 (testset)other0.005490.99451 other
TEL-AML1-C53 (testset)other0.03340.9666 other
TEL-AML1-C54 (testset)other0.000880.99912 other
TEL-AML1-C55 (testset)other0.004620.99538 other
TEL-AML1-C56 (testset)other0.001890.99811 other
TEL-AML1-C57 (testset)other0.010080.98992 other
TEL-AML1-C5 (testset)other0.00210.9979 other
TEL-AML1-C6 (testset)other0.002690.99731 other
TEL-AML1-C7 (testset)other0.001170.99883 other
TEL-AML1-C8 (testset)other0.000760.99924 other
TEL-AML1-C9 (testset)other0.018240.98176 other
TEL-AML1-R1 (testset)other0.003760.99624 other
TEL-AML1-R2 (testset)other0.004810.99519 other
TEL-AML1-R3 (testset)other0.001330.99867 other

 


Generated by StAM on Tue Sep 7 18:40:16 2004