GO:0007186

GO:0007186

G-protein coupled receptor protein signaling pathway (annotated genes)

Biological Process

Parent node

GO:0007186	G-protein coupled receptor protein signaling pathway

This leaf node contains 273 genes

The following 19 of these are used in classification:

	Symbol	Genename	T-ALL score	other score
36277_at	CD3E	CD3E antigen, epsilon polypeptide (TiT3 complex)	2.9251	-0.4488
649_s_at	CXCR4	chemokine (C-X-C motif) receptor 4	-0.7223	0.1108
40365_at	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	0.7221	-0.1108
39441_at	LANCL1	LanC lantibiotic synthetase component C-like 1 (bacterial)	0.5163	-0.0792
32009_at	CCR9	chemokine (C-C motif) receptor 9	0.3597	-0.0552
34806_at	GPR44	G protein-coupled receptor 44	0.341	-0.0523
41143_at	CALM1	calmodulin 1 (phosphorylase kinase, delta)	-0.2804	0.043
33602_at	EDG6	endothelial differentiation, G-protein-coupled receptor 6	-0.1704	0.0262
41288_at	CALM1	calmodulin 1 (phosphorylase kinase, delta)	-0.1567	0.024
37908_at	GNG11	guanine nucleotide binding protein (G protein), gamma 11	-0.1375	0.0211
32114_s_at	ADORA2A	adenosine A2a receptor	0.1284	-0.0197
336_at	TBXA2R	thromboxane A2 receptor	-0.1128	0.0173
40646_at	CX3CR1	chemokine (C-X3-C motif) receptor 1	0.1083	-0.0166
35272_at	GNG5	guanine nucleotide binding protein (G protein), gamma 5	0.0669	-0.0103
36799_at	FZD2	frizzled homolog 2 (Drosophila)	-0.0572	0.0088
34268_at	RGS19	regulator of G-protein signalling 19	-0.0563	0.0086
1369_s_at	IL8	interleukin 8	0.03	-0.0046
33772_at	PTGER4	prostaglandin E receptor 4 (subtype EP4)	0.03	-0.0046
1118_at	PTGER4	prostaglandin E receptor 4 (subtype EP4)	0.005	-8e-04

Performance on training data

• Error rate: 0
• Performance: 0.01311
• Redundancy: 6.05342

	Sensitivity	Specificity
T-ALL	1	1
other	1	1

Performance on test data

• Error rate: 0.01835
• Performance: 0.12594
• Redundancy: 6.02426

	Sensitivity	Specificity
T-ALL	0.85714	1
other	1	0.85714

Predictions

	Class	T-ALL	other	Predictionn
BCR-ABL-1	other	4e-05	0.99996	other
BCR-ABL-2	other	0.00117	0.99883	other
BCR-ABL-3 (testset)	other	4e-05	0.99996	other
BCR-ABL-4	other	5e-05	0.99995	other
BCR-ABL-5	other	0.00038	0.99962	other
BCR-ABL-6 (testset)	other	6e-05	0.99994	other
BCR-ABL-7 (testset)	other	0.00122	0.99878	other
BCR-ABL-8 (testset)	other	2e-05	0.99998	other
BCR-ABL-9 (testset)	other	0.00114	0.99886	other
BCR-ABL-C1 (testset)	other	5e-05	0.99995	other
BCR-ABL-Hyperdip-10 (testset)	other	2e-05	0.99998	other
BCR-ABL-Hyperdip-R5	other	1e-05	0.99999	other
BCR-ABL-R1	other	5e-05	0.99995	other
BCR-ABL-R2	other	0.00353	0.99647	other
BCR-ABL-R3 (testset)	other	0.00074	0.99926	other
E2A-PBX1-10	other	5e-05	0.99995	other
E2A-PBX1-11	other	4e-05	0.99996	other
E2A-PBX1-12 (testset)	other	0.00022	0.99978	other
E2A-PBX1-13	other	0.00011	0.99989	other
E2A-PBX1-1	other	1e-05	0.99999	other
E2A-PBX1-2	other	2e-05	0.99998	other
E2A-PBX1-3	other	1e-05	0.99999	other
E2A-PBX1-4 (testset)	other	7e-05	0.99993	other
E2A-PBX1-5	other	6e-05	0.99994	other
E2A-PBX1-6	other	2e-05	0.99998	other
E2A-PBX1-7	other	0.00018	0.99982	other
E2A-PBX1-8	other	5e-05	0.99995	other
E2A-PBX1-9	other	2e-05	0.99998	other
E2A-PBX1-2M1	other	0	1	other
E2A-PBX1-C10	other	2e-04	0.9998	other
E2A-PBX1-C11	other	0.00022	0.99978	other
E2A-PBX1-C12	other	0.00011	0.99989	other
E2A-PBX1-C1	other	0.00205	0.99795	other
E2A-PBX1-C2	other	5e-05	0.99995	other
E2A-PBX1-C3 (testset)	other	5e-05	0.99995	other
E2A-PBX1-C4	other	8e-05	0.99992	other
E2A-PBX1-C5 (testset)	other	5e-05	0.99995	other
E2A-PBX1-C6	other	0	1	other
E2A-PBX1-C7	other	0	1	other
E2A-PBX1-C8	other	0.00075	0.99925	other
E2A-PBX1-C9	other	3e-05	0.99997	other
E2A-PBX1-R1	other	0	1	other
Hyperdip-50-10	other	3e-04	0.9997	other
Hyperdip-50-11 (testset)	other	0.00019	0.99981	other
Hyperdip-50-12	other	4e-05	0.99996	other
Hyperdip-50-13 (testset)	other	1e-05	0.99999	other
Hyperdip-50-14	other	0	1	other
Hyperdip-50-1	other	0.00021	0.99979	other
Hyperdip-50-2	other	2e-05	0.99998	other
Hyperdip-50-3 (testset)	other	5e-05	0.99995	other
Hyperdip-50-4 (testset)	other	0.00058	0.99942	other
Hyperdip-50-5 (testset)	other	3e-05	0.99997	other
Hyperdip-50-6	other	9e-05	0.99991	other
Hyperdip-50-7	other	0.00082	0.99918	other
Hyperdip-50-8 (testset)	other	1e-05	0.99999	other
Hyperdip-50-9	other	2e-05	0.99998	other
Hyperdip-50-2M1	other	0.00078	0.99922	other
Hyperdip-50-2M2 (testset)	other	1e-05	0.99999	other
Hyperdip-50-C10	other	0	1	other
Hyperdip-50-C11 (testset)	other	2e-05	0.99998	other
Hyperdip-50-C12	other	0.00018	0.99982	other
Hyperdip-50-C13	other	0.00014	0.99986	other
Hyperdip-50-C14	other	0	1	other
Hyperdip-50-C15	other	7e-05	0.99993	other
Hyperdip-50-C16	other	0.00011	0.99989	other
Hyperdip-50-C17	other	1e-05	0.99999	other
Hyperdip-50-C18	other	2e-05	0.99998	other
Hyperdip-50-C19 (testset)	other	2e-05	0.99998	other
Hyperdip-50-C1	other	0.00027	0.99973	other
Hyperdip-50-C20	other	0.00018	0.99982	other
Hyperdip-50-C21	other	1e-05	0.99999	other
Hyperdip-50-C22 (testset)	other	3e-05	0.99997	other
Hyperdip-50-C23	other	7e-05	0.99993	other
Hyperdip-50-C24	other	1e-05	0.99999	other
Hyperdip-50-C25	other	1e-05	0.99999	other
Hyperdip-50-C26	other	6e-05	0.99994	other
Hyperdip-50-C27-N	other	0.00017	0.99983	other
Hyperdip-50-C28	other	0.00211	0.99789	other
Hyperdip-50-C29 (testset)	other	0.00058	0.99942	other
Hyperdip-50-C2 (testset)	other	0.00172	0.99828	other
Hyperdip-50-C30	other	1e-05	0.99999	other
Hyperdip-50-C31	other	4e-05	0.99996	other
Hyperdip-50-C32	other	0	1	other
Hyperdip-50-C33	other	8e-05	0.99992	other
Hyperdip-50-C34	other	1e-05	0.99999	other
Hyperdip-50-C35 (testset)	other	4e-05	0.99996	other
Hyperdip-50-C36	other	1e-05	0.99999	other
Hyperdip-50-C37	other	0.00012	0.99988	other
Hyperdip-50-C38	other	0	1	other
Hyperdip-50-C39 (testset)	other	3e-05	0.99997	other
Hyperdip-50-C3	other	3e-05	0.99997	other
Hyperdip-50-C40	other	3e-05	0.99997	other
Hyperdip-50-C41 (testset)	other	0.00019	0.99981	other
Hyperdip-50-C42 (testset)	other	5e-04	0.9995	other
Hyperdip-50-C43	other	0.00075	0.99925	other
Hyperdip-50-C4	other	0.00014	0.99986	other
Hyperdip-50-C5 (testset)	other	0.00071	0.99929	other
Hyperdip-50-C6	other	3e-05	0.99997	other
Hyperdip-50-C7 (testset)	other	0	1	other
Hyperdip-50-C8 (testset)	other	0	1	other
Hyperdip-50-C9	other	0.00011	0.99989	other
Hyperdip-50-R1	other	0.00072	0.99928	other
Hyperdip-50-R2 (testset)	other	0.00072	0.99928	other
Hyperdip-50-R3	other	8e-05	0.99992	other
Hyperdip-50-R4	other	0	1	other
Hyperdip-50-R5 (testset)	other	2e-05	0.99998	other
Hyperdip47-50-1	other	2e-05	0.99998	other
Hyperdip47-50-2	other	9e-05	0.99991	other
Hyperdip47-50-3 (testset)	other	1e-05	0.99999	other
Hyperdip47-50-2M1 (testset)	other	1e-05	0.99999	other
Hyperdip47-50-C10 (testset)	other	0.00045	0.99955	other
Hyperdip47-50-C11	other	0.00038	0.99962	other
Hyperdip47-50-C12	other	2e-05	0.99998	other
Hyperdip47-50-C13	other	4e-05	0.99996	other
Hyperdip47-50-C14-N (testset)	other	8e-05	0.99992	other
Hyperdip47-50-C15 (testset)	other	0.00012	0.99988	other
Hyperdip47-50-C16	other	0.00179	0.99821	other
Hyperdip47-50-C17	other	1e-04	0.9999	other
Hyperdip47-50-C18	other	5e-05	0.99995	other
Hyperdip47-50-C19	other	0.0011	0.9989	other
Hyperdip47-50-C1 (testset)	other	0.00037	0.99963	other
Hyperdip47-50-C2 (testset)	other	0.00074	0.99926	other
Hyperdip47-50-C3-N (testset)	other	5e-05	0.99995	other
Hyperdip47-50-C4	other	0.00025	0.99975	other
Hyperdip47-50-C5 (testset)	other	0.00021	0.99979	other
Hyperdip47-50-C6 (testset)	other	4e-05	0.99996	other
Hyperdip47-50-C7	other	0.00064	0.99936	other
Hyperdip47-50-C8	other	1e-05	0.99999	other
Hyperdip47-50-C9	other	0.00014	0.99986	other
Hypodip-1 (testset)	other	7e-05	0.99993	other
Hypodip-2	other	0.19758	0.80242	other
Hypodip-2M1 (testset)	other	0.00227	0.99773	other
Hypodip-C1	other	4e-05	0.99996	other
Hypodip-C2 (testset)	other	0.00094	0.99906	other
Hypodip-C3	other	0.00041	0.99959	other
Hypodip-C4	other	0.00199	0.99801	other
Hypodip-C5	other	6e-05	0.99994	other
Hypodip-C6 (testset)	other	5e-05	0.99995	other
MLL-1 (testset)	other	6e-05	0.99994	other
MLL-2	other	5e-05	0.99995	other
MLL-3 (testset)	other	4e-05	0.99996	other
MLL-4	other	1e-04	0.9999	other
MLL-5 (testset)	other	0	1	other
MLL-6 (testset)	other	0	1	other
MLL-7	other	2e-05	0.99998	other
MLL-8 (testset)	other	0.00026	0.99974	other
MLL-2M1	other	0.00054	0.99946	other
MLL-2M2 (testset)	other	2e-04	0.9998	other
MLL-C1	other	1e-04	0.9999	other
MLL-C2	other	0.00024	0.99976	other
MLL-C3 (testset)	other	0.00029	0.99971	other
MLL-C4	other	8e-05	0.99992	other
MLL-C5	other	4e-05	0.99996	other
MLL-C6	other	0.00093	0.99907	other
MLL-R1 (testset)	other	1e-05	0.99999	other
MLL-R2	other	2e-04	0.9998	other
MLL-R3	other	8e-05	0.99992	other
MLL-R4	other	3e-05	0.99997	other
Normal-1	other	1e-04	0.9999	other
Normal-2	other	6e-05	0.99994	other
Normal-3	other	0.00094	0.99906	other
Normal-C1-N	other	0.00244	0.99756	other
Normal-C10	other	3e-05	0.99997	other
Normal-C11-N (testset)	other	0.00088	0.99912	other
Normal-C12 (testset)	other	0.00192	0.99808	other
Normal-C2-N	other	0.00011	0.99989	other
Normal-C3-N	other	0.00098	0.99902	other
Normal-C4-N	other	8e-05	0.99992	other
Normal-C5	other	0.00033	0.99967	other
Normal-C6 (testset)	other	7e-05	0.99993	other
Normal-C7-N (testset)	other	4e-05	0.99996	other
Normal-C8	other	0	1	other
Normal-C9 (testset)	other	5e-05	0.99995	other
Normal-R1 (testset)	other	0.00061	0.99939	other
Normal-R2-N	other	0.00048	0.99952	other
Normal-R3	other	6e-05	0.99994	other
Pseudodip-1	other	2e-05	0.99998	other
Pseudodip-2	other	0.00348	0.99652	other
Pseudodip-3	other	0.00018	0.99982	other
Pseudodip-4 (testset)	other	0.00015	0.99985	other
Pseudodip-5 (testset)	other	0.00031	0.99969	other
Pseudodip-6 (testset)	other	0.00019	0.99981	other
Pseudodip-7	other	9e-05	0.99991	other
Pseudodip-8-N	other	2e-05	0.99998	other
Pseudodip-9	other	9e-05	0.99991	other
Pseudodip-C10 (testset)	other	0.00013	0.99987	other
Pseudodip-C11 (testset)	other	3e-05	0.99997	other
Pseudodip-C12 (testset)	other	0.00021	0.99979	other
Pseudodip-C13	other	1e-04	0.9999	other
Pseudodip-C14 (testset)	other	0.00016	0.99984	other
Pseudodip-C15	other	1e-05	0.99999	other
Pseudodip-C16-N (testset)	other	0.02315	0.97685	other
Pseudodip-C17	other	3e-05	0.99997	other
Pseudodip-C18	other	7e-05	0.99993	other
Pseudodip-C19	other	7e-05	0.99993	other
Pseudodip-C1	other	0.00023	0.99977	other
Pseudodip-C2-N	other	0.00052	0.99948	other
Pseudodip-C3	other	0.00072	0.99928	other
Pseudodip-C4	other	0.00018	0.99982	other
Pseudodip-C5 (testset)	other	2e-05	0.99998	other
Pseudodip-C6	other	0.00013	0.99987	other
Pseudodip-C7	other	5e-05	0.99995	other
Pseudodip-C8	other	4e-05	0.99996	other
Pseudodip-C9	other	6e-05	0.99994	other
Pseudodip-R1-N (testset)	other	4e-05	0.99996	other
T-ALL-10 (testset)	T-ALL	1	0	T-ALL
T-ALL-1 (testset)	T-ALL	0.99665	0.00335	T-ALL
T-ALL-2 (testset)	T-ALL	0.02574	0.97426	other
T-ALL-3	T-ALL	1	0	T-ALL
T-ALL-4 (testset)	T-ALL	0.99992	8e-05	T-ALL
T-ALL-5 (testset)	T-ALL	1	0	T-ALL
T-ALL-6	T-ALL	0.99992	8e-05	T-ALL
T-ALL-7 (testset)	T-ALL	1	0	T-ALL
T-ALL-8 (testset)	T-ALL	0.99997	3e-05	T-ALL
T-ALL-9	T-ALL	0.99999	1e-05	T-ALL
T-ALL-2M1	T-ALL	1	0	T-ALL
T-ALL-C10	T-ALL	1	0	T-ALL
T-ALL-C11	T-ALL	0.99829	0.00171	T-ALL
T-ALL-C12	T-ALL	1	0	T-ALL
T-ALL-C13	T-ALL	0.99957	0.00043	T-ALL
T-ALL-C14	T-ALL	0.8269	0.1731	T-ALL
T-ALL-C15 (testset)	T-ALL	1	0	T-ALL
T-ALL-C16 (testset)	T-ALL	0.89968	0.10032	T-ALL
T-ALL-C17	T-ALL	0.99634	0.00366	T-ALL
T-ALL-C18	T-ALL	0.99999	1e-05	T-ALL
T-ALL-C19	T-ALL	0.99966	0.00034	T-ALL
T-ALL-C1	T-ALL	0.95601	0.04399	T-ALL
T-ALL-C20	T-ALL	0.99989	0.00011	T-ALL
T-ALL-C21	T-ALL	0.99983	0.00017	T-ALL
T-ALL-C22 (testset)	T-ALL	1	0	T-ALL
T-ALL-C23	T-ALL	0.98601	0.01399	T-ALL
T-ALL-C24 (testset)	T-ALL	0.99955	0.00045	T-ALL
T-ALL-C25 (testset)	T-ALL	0.99995	5e-05	T-ALL
T-ALL-C26	T-ALL	0.79435	0.20565	T-ALL
T-ALL-C2	T-ALL	0.99971	0.00029	T-ALL
T-ALL-C3	T-ALL	1	0	T-ALL
T-ALL-C4	T-ALL	0.99964	0.00036	T-ALL
T-ALL-C5 (testset)	T-ALL	0.06102	0.93898	other
T-ALL-C6	T-ALL	0.99989	0.00011	T-ALL
T-ALL-C7 (testset)	T-ALL	1	0	T-ALL
T-ALL-C8	T-ALL	0.53625	0.46375	T-ALL
T-ALL-C9	T-ALL	0.98872	0.01128	T-ALL
T-ALL-R1	T-ALL	0.99999	1e-05	T-ALL
T-ALL-R2	T-ALL	1	0	T-ALL
T-ALL-R3	T-ALL	1	0	T-ALL
T-ALL-R4	T-ALL	0.9774	0.0226	T-ALL
T-ALL-R5	T-ALL	0.99914	0.00086	T-ALL
T-ALL-R6	T-ALL	0.99995	5e-05	T-ALL
TEL-AML1-10	other	0.00024	0.99976	other
TEL-AML1-11 (testset)	other	0	1	other
TEL-AML1-12	other	0.00084	0.99916	other
TEL-AML1-13 (testset)	other	8e-05	0.99992	other
TEL-AML1-14	other	0.00049	0.99951	other
TEL-AML1-1	other	0.00042	0.99958	other
TEL-AML1-2	other	0.00013	0.99987	other
TEL-AML1-3	other	0.00461	0.99539	other
TEL-AML1-4	other	9e-05	0.99991	other
TEL-AML1-5 (testset)	other	0.00046	0.99954	other
TEL-AML1-6	other	4e-05	0.99996	other
TEL-AML1-7	other	0.00062	0.99938	other
TEL-AML1-8 (testset)	other	0.00046	0.99954	other
TEL-AML1-9	other	5e-05	0.99995	other
TEL-AML1-2M1 (testset)	other	2e-05	0.99998	other
TEL-AML1-2M2	other	4e-05	0.99996	other
TEL-AML1-2M3	other	0.00083	0.99917	other
TEL-AML1-2M4 (testset)	other	0.00654	0.99346	other
TEL-AML1-2M5	other	1e-05	0.99999	other
TEL-AML1-C10	other	0.00027	0.99973	other
TEL-AML1-C11	other	0.00072	0.99928	other
TEL-AML1-C12	other	0.00015	0.99985	other
TEL-AML1-C13	other	0.00041	0.99959	other
TEL-AML1-C14 (testset)	other	6e-05	0.99994	other
TEL-AML1-C15	other	0.00355	0.99645	other
TEL-AML1-C16	other	3e-05	0.99997	other
TEL-AML1-C17	other	0.00168	0.99832	other
TEL-AML1-C18	other	1e-04	0.9999	other
TEL-AML1-C19 (testset)	other	5e-05	0.99995	other
TEL-AML1-C1 (testset)	other	1e-04	0.9999	other
TEL-AML1-C20 (testset)	other	2e-05	0.99998	other
TEL-AML1-C21	other	0.00039	0.99961	other
TEL-AML1-C22	other	5e-05	0.99995	other
TEL-AML1-C23 (testset)	other	0.00026	0.99974	other
TEL-AML1-C24	other	4e-05	0.99996	other
TEL-AML1-C25	other	0.00062	0.99938	other
TEL-AML1-C26 (testset)	other	1e-05	0.99999	other
TEL-AML1-C27	other	0.00017	0.99983	other
TEL-AML1-C28 (testset)	other	0.00011	0.99989	other
TEL-AML1-C29	other	3e-05	0.99997	other
TEL-AML1-C2	other	2e-05	0.99998	other
TEL-AML1-C30	other	0.00027	0.99973	other
TEL-AML1-C31 (testset)	other	0	1	other
TEL-AML1-C32	other	2e-05	0.99998	other
TEL-AML1-C33 (testset)	other	1e-04	0.9999	other
TEL-AML1-C34	other	3e-05	0.99997	other
TEL-AML1-C35	other	2e-05	0.99998	other
TEL-AML1-C36 (testset)	other	0.00011	0.99989	other
TEL-AML1-C37	other	1e-05	0.99999	other
TEL-AML1-C38	other	1e-05	0.99999	other
TEL-AML1-C39	other	0.00026	0.99974	other
TEL-AML1-C3	other	7e-05	0.99993	other
TEL-AML1-C40	other	1e-05	0.99999	other
TEL-AML1-C41	other	0.00035	0.99965	other
TEL-AML1-C42	other	0.00042	0.99958	other
TEL-AML1-C43	other	0	1	other
TEL-AML1-C44	other	3e-05	0.99997	other
TEL-AML1-C45	other	0.00017	0.99983	other
TEL-AML1-C46	other	0.00017	0.99983	other
TEL-AML1-C47	other	1e-05	0.99999	other
TEL-AML1-C48	other	0.00213	0.99787	other
TEL-AML1-C49 (testset)	other	0.00017	0.99983	other
TEL-AML1-C4 (testset)	other	0.00023	0.99977	other
TEL-AML1-C50	other	0.00018	0.99982	other
TEL-AML1-C51 (testset)	other	8e-05	0.99992	other
TEL-AML1-C52	other	0.00098	0.99902	other
TEL-AML1-C53 (testset)	other	0.00909	0.99091	other
TEL-AML1-C54	other	0.00063	0.99937	other
TEL-AML1-C55 (testset)	other	0.00053	0.99947	other
TEL-AML1-C56	other	0.00011	0.99989	other
TEL-AML1-C57	other	0.00017	0.99983	other
TEL-AML1-C5 (testset)	other	0.00053	0.99947	other
TEL-AML1-C6	other	1e-05	0.99999	other
TEL-AML1-C7	other	3e-04	0.9997	other
TEL-AML1-C8	other	0.00018	0.99982	other
TEL-AML1-C9	other	0.00253	0.99747	other
TEL-AML1-R1 (testset)	other	0.00063	0.99937	other
TEL-AML1-R2 (testset)	other	1e-04	0.9999	other
TEL-AML1-R3	other	1e-05	0.99999	other