GO:0007169

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

Biological Process

Parent node

GO:0007167	enzyme linked receptor protein signaling pathway

7 child nodes

ID	Term	Weight
GO:0007173	EGF receptor signaling pathway	0.00000
GO:0008543	FGF receptor signaling pathway	0.00000
GO:0008286	insulin receptor signaling pathway	0.00000
GO:0007172	signal complex formation	0.00000
GO:0007171	transmembrane receptor protein tyrosine kinase activation (dimerization)	0.00000
GO:0007170	transmembrane receptor protein tyrosine kinase ligand binding	0.00000
GO:0007169a	transmembrane receptor protein tyrosine kinase signaling pathway (annotated genes)	1

Performance on training data

• Error rate: 0.01835
• Performance: 0.12445
• Redundancy: 3.76077

	Sensitivity	Specificity
T-ALL	0.86207	1
other	1	0.86207

Performance on test data

• Error rate: 0.02752
• Performance: 0.1975
• Redundancy: 3.66892

	Sensitivity	Specificity
T-ALL	0.78571	1
other	1	0.78571

Predictions

	Class	T-ALL	other	Predictionn
BCR-ABL-1	other	0.07512	0.92488	other
BCR-ABL-2	other	0.07266	0.92734	other
BCR-ABL-3 (testset)	other	0.03625	0.96375	other
BCR-ABL-4	other	0.02359	0.97641	other
BCR-ABL-5	other	0.01723	0.98277	other
BCR-ABL-6 (testset)	other	0.03285	0.96715	other
BCR-ABL-7 (testset)	other	0.04756	0.95244	other
BCR-ABL-8 (testset)	other	0.00836	0.99164	other
BCR-ABL-9 (testset)	other	0.00954	0.99046	other
BCR-ABL-C1 (testset)	other	0.01127	0.98873	other
BCR-ABL-Hyperdip-10 (testset)	other	0.02577	0.97423	other
BCR-ABL-Hyperdip-R5	other	0.01869	0.98131	other
BCR-ABL-R1	other	0.02403	0.97597	other
BCR-ABL-R2	other	0.05631	0.94369	other
BCR-ABL-R3 (testset)	other	0.12516	0.87484	other
E2A-PBX1-10	other	0.00208	0.99792	other
E2A-PBX1-11	other	0.00481	0.99519	other
E2A-PBX1-12 (testset)	other	0.00764	0.99236	other
E2A-PBX1-13	other	0.01046	0.98954	other
E2A-PBX1-1	other	0.01468	0.98532	other
E2A-PBX1-2	other	0.00934	0.99066	other
E2A-PBX1-3	other	0.0065	0.9935	other
E2A-PBX1-4 (testset)	other	0.00515	0.99485	other
E2A-PBX1-5	other	0.00459	0.99541	other
E2A-PBX1-6	other	0.0067	0.9933	other
E2A-PBX1-7	other	0.00852	0.99148	other
E2A-PBX1-8	other	0.00322	0.99678	other
E2A-PBX1-9	other	0.00192	0.99808	other
E2A-PBX1-2M1	other	0.00937	0.99063	other
E2A-PBX1-C10	other	0.01824	0.98176	other
E2A-PBX1-C11	other	0.00591	0.99409	other
E2A-PBX1-C12	other	0.01226	0.98774	other
E2A-PBX1-C1	other	0.05924	0.94076	other
E2A-PBX1-C2	other	0.01041	0.98959	other
E2A-PBX1-C3 (testset)	other	0.00219	0.99781	other
E2A-PBX1-C4	other	0.00773	0.99227	other
E2A-PBX1-C5 (testset)	other	0.00492	0.99508	other
E2A-PBX1-C6	other	0.0062	0.9938	other
E2A-PBX1-C7	other	0.00225	0.99775	other
E2A-PBX1-C8	other	0.10961	0.89039	other
E2A-PBX1-C9	other	0.00461	0.99539	other
E2A-PBX1-R1	other	0.00968	0.99032	other
Hyperdip-50-10	other	0.07418	0.92582	other
Hyperdip-50-11 (testset)	other	0.19289	0.80711	other
Hyperdip-50-12	other	0.01673	0.98327	other
Hyperdip-50-13 (testset)	other	0.01547	0.98453	other
Hyperdip-50-14	other	0.00303	0.99697	other
Hyperdip-50-1	other	0.00957	0.99043	other
Hyperdip-50-2	other	0.01853	0.98147	other
Hyperdip-50-3 (testset)	other	0.01729	0.98271	other
Hyperdip-50-4 (testset)	other	0.13637	0.86363	other
Hyperdip-50-5 (testset)	other	0.005	0.995	other
Hyperdip-50-6	other	0.01164	0.98836	other
Hyperdip-50-7	other	0.00747	0.99253	other
Hyperdip-50-8 (testset)	other	0.00412	0.99588	other
Hyperdip-50-9	other	0.02326	0.97674	other
Hyperdip-50-2M1	other	0.03477	0.96523	other
Hyperdip-50-2M2 (testset)	other	0.00866	0.99134	other
Hyperdip-50-C10	other	0.00945	0.99055	other
Hyperdip-50-C11 (testset)	other	0.00235	0.99765	other
Hyperdip-50-C12	other	0.02257	0.97743	other
Hyperdip-50-C13	other	0.01939	0.98061	other
Hyperdip-50-C14	other	0.01392	0.98608	other
Hyperdip-50-C15	other	0.00989	0.99011	other
Hyperdip-50-C16	other	0.03085	0.96915	other
Hyperdip-50-C17	other	0.01597	0.98403	other
Hyperdip-50-C18	other	0.00311	0.99689	other
Hyperdip-50-C19 (testset)	other	0.01917	0.98083	other
Hyperdip-50-C1	other	0.00741	0.99259	other
Hyperdip-50-C20	other	0.0191	0.9809	other
Hyperdip-50-C21	other	0.01006	0.98994	other
Hyperdip-50-C22 (testset)	other	0.0045	0.9955	other
Hyperdip-50-C23	other	0.00806	0.99194	other
Hyperdip-50-C24	other	0.03796	0.96204	other
Hyperdip-50-C25	other	0.00279	0.99721	other
Hyperdip-50-C26	other	0.00555	0.99445	other
Hyperdip-50-C27-N	other	0.01233	0.98767	other
Hyperdip-50-C28	other	0.01774	0.98226	other
Hyperdip-50-C29 (testset)	other	0.00675	0.99325	other
Hyperdip-50-C2 (testset)	other	0.04275	0.95725	other
Hyperdip-50-C30	other	0.01897	0.98103	other
Hyperdip-50-C31	other	0.01269	0.98731	other
Hyperdip-50-C32	other	0.00767	0.99233	other
Hyperdip-50-C33	other	0.00475	0.99525	other
Hyperdip-50-C34	other	0.01587	0.98413	other
Hyperdip-50-C35 (testset)	other	0.04231	0.95769	other
Hyperdip-50-C36	other	0.02201	0.97799	other
Hyperdip-50-C37	other	0.0189	0.9811	other
Hyperdip-50-C38	other	0.0128	0.9872	other
Hyperdip-50-C39 (testset)	other	0.01913	0.98087	other
Hyperdip-50-C3	other	0.00606	0.99394	other
Hyperdip-50-C40	other	0.01705	0.98295	other
Hyperdip-50-C41 (testset)	other	0.03752	0.96248	other
Hyperdip-50-C42 (testset)	other	0.05322	0.94678	other
Hyperdip-50-C43	other	0.01639	0.98361	other
Hyperdip-50-C4	other	0.01133	0.98867	other
Hyperdip-50-C5 (testset)	other	0.04385	0.95615	other
Hyperdip-50-C6	other	0.00411	0.99589	other
Hyperdip-50-C7 (testset)	other	0.01192	0.98808	other
Hyperdip-50-C8 (testset)	other	0.00693	0.99307	other
Hyperdip-50-C9	other	0.00972	0.99028	other
Hyperdip-50-R1	other	0.0878	0.9122	other
Hyperdip-50-R2 (testset)	other	0.00798	0.99202	other
Hyperdip-50-R3	other	0.00691	0.99309	other
Hyperdip-50-R4	other	0.0219	0.9781	other
Hyperdip-50-R5 (testset)	other	0.01285	0.98715	other
Hyperdip47-50-1	other	0.01296	0.98704	other
Hyperdip47-50-2	other	0.03237	0.96763	other
Hyperdip47-50-3 (testset)	other	0.00418	0.99582	other
Hyperdip47-50-2M1 (testset)	other	0.01227	0.98773	other
Hyperdip47-50-C10 (testset)	other	0.01468	0.98532	other
Hyperdip47-50-C11	other	0.02838	0.97162	other
Hyperdip47-50-C12	other	0.02164	0.97836	other
Hyperdip47-50-C13	other	0.00448	0.99552	other
Hyperdip47-50-C14-N (testset)	other	0.00991	0.99009	other
Hyperdip47-50-C15 (testset)	other	0.02097	0.97903	other
Hyperdip47-50-C16	other	0.0024	0.9976	other
Hyperdip47-50-C17	other	0.03055	0.96945	other
Hyperdip47-50-C18	other	0.01156	0.98844	other
Hyperdip47-50-C19	other	0.03737	0.96263	other
Hyperdip47-50-C1 (testset)	other	0.00635	0.99365	other
Hyperdip47-50-C2 (testset)	other	0.06853	0.93147	other
Hyperdip47-50-C3-N (testset)	other	0.0084	0.9916	other
Hyperdip47-50-C4	other	0.00771	0.99229	other
Hyperdip47-50-C5 (testset)	other	0.00211	0.99789	other
Hyperdip47-50-C6 (testset)	other	0.02284	0.97716	other
Hyperdip47-50-C7	other	0.03026	0.96974	other
Hyperdip47-50-C8	other	0.0235	0.9765	other
Hyperdip47-50-C9	other	0.00608	0.99392	other
Hypodip-1 (testset)	other	0.00435	0.99565	other
Hypodip-2	other	0.06647	0.93353	other
Hypodip-2M1 (testset)	other	0.06647	0.93353	other
Hypodip-C1	other	0.01313	0.98687	other
Hypodip-C2 (testset)	other	0.01859	0.98141	other
Hypodip-C3	other	0.00837	0.99163	other
Hypodip-C4	other	0.01757	0.98243	other
Hypodip-C5	other	0.01134	0.98866	other
Hypodip-C6 (testset)	other	0.0076	0.9924	other
MLL-1 (testset)	other	0.00607	0.99393	other
MLL-2	other	0.00681	0.99319	other
MLL-3 (testset)	other	0.00474	0.99526	other
MLL-4	other	0.00926	0.99074	other
MLL-5 (testset)	other	0.00288	0.99712	other
MLL-6 (testset)	other	0.03165	0.96835	other
MLL-7	other	0.00494	0.99506	other
MLL-8 (testset)	other	0.00458	0.99542	other
MLL-2M1	other	0.0087	0.9913	other
MLL-2M2 (testset)	other	0.00297	0.99703	other
MLL-C1	other	0.00195	0.99805	other
MLL-C2	other	0.01372	0.98628	other
MLL-C3 (testset)	other	0.00508	0.99492	other
MLL-C4	other	0.00597	0.99403	other
MLL-C5	other	0.01186	0.98814	other
MLL-C6	other	0.01043	0.98957	other
MLL-R1 (testset)	other	0.01667	0.98333	other
MLL-R2	other	0.00392	0.99608	other
MLL-R3	other	0.01331	0.98669	other
MLL-R4	other	0.01422	0.98578	other
Normal-1	other	0.01556	0.98444	other
Normal-2	other	0.01828	0.98172	other
Normal-3	other	0.01526	0.98474	other
Normal-C1-N	other	0.01849	0.98151	other
Normal-C10	other	0.00544	0.99456	other
Normal-C11-N (testset)	other	0.01623	0.98377	other
Normal-C12 (testset)	other	0.02337	0.97663	other
Normal-C2-N	other	0.01188	0.98812	other
Normal-C3-N	other	0.00676	0.99324	other
Normal-C4-N	other	0.01063	0.98937	other
Normal-C5	other	0.09328	0.90672	other
Normal-C6 (testset)	other	0.00373	0.99627	other
Normal-C7-N (testset)	other	0.00945	0.99055	other
Normal-C8	other	0.00762	0.99238	other
Normal-C9 (testset)	other	0.007	0.993	other
Normal-R1 (testset)	other	0.02956	0.97044	other
Normal-R2-N	other	0.01978	0.98022	other
Normal-R3	other	0.01414	0.98586	other
Pseudodip-1	other	0.00705	0.99295	other
Pseudodip-2	other	0.06998	0.93002	other
Pseudodip-3	other	0.0082	0.9918	other
Pseudodip-4 (testset)	other	0.03529	0.96471	other
Pseudodip-5 (testset)	other	0.01653	0.98347	other
Pseudodip-6 (testset)	other	0.00451	0.99549	other
Pseudodip-7	other	0.01002	0.98998	other
Pseudodip-8-N	other	0.00116	0.99884	other
Pseudodip-9	other	0.05919	0.94081	other
Pseudodip-C10 (testset)	other	0.01565	0.98435	other
Pseudodip-C11 (testset)	other	0.00626	0.99374	other
Pseudodip-C12 (testset)	other	0.016	0.984	other
Pseudodip-C13	other	0.01669	0.98331	other
Pseudodip-C14 (testset)	other	0.01502	0.98498	other
Pseudodip-C15	other	0.0099	0.9901	other
Pseudodip-C16-N (testset)	other	0.10554	0.89446	other
Pseudodip-C17	other	0.00673	0.99327	other
Pseudodip-C18	other	0.04089	0.95911	other
Pseudodip-C19	other	0.02443	0.97557	other
Pseudodip-C1	other	0.03905	0.96095	other
Pseudodip-C2-N	other	0.00702	0.99298	other
Pseudodip-C3	other	0.00211	0.99789	other
Pseudodip-C4	other	0.00669	0.99331	other
Pseudodip-C5 (testset)	other	0.00422	0.99578	other
Pseudodip-C6	other	0.02577	0.97423	other
Pseudodip-C7	other	0.00594	0.99406	other
Pseudodip-C8	other	0.00378	0.99622	other
Pseudodip-C9	other	0.00841	0.99159	other
Pseudodip-R1-N (testset)	other	0.0058	0.9942	other
T-ALL-10 (testset)	T-ALL	0.83817	0.16183	T-ALL
T-ALL-1 (testset)	T-ALL	0.77232	0.22768	T-ALL
T-ALL-2 (testset)	T-ALL	0.01487	0.98513	other
T-ALL-3	T-ALL	0.99968	0.00032	T-ALL
T-ALL-4 (testset)	T-ALL	0.97537	0.02463	T-ALL
T-ALL-5 (testset)	T-ALL	0.97104	0.02896	T-ALL
T-ALL-6	T-ALL	0.67301	0.32699	T-ALL
T-ALL-7 (testset)	T-ALL	0.99453	0.00547	T-ALL
T-ALL-8 (testset)	T-ALL	0.94087	0.05913	T-ALL
T-ALL-9	T-ALL	0.88217	0.11783	T-ALL
T-ALL-2M1	T-ALL	0.99996	4e-05	T-ALL
T-ALL-C10	T-ALL	0.99213	0.00787	T-ALL
T-ALL-C11	T-ALL	0.9646	0.0354	T-ALL
T-ALL-C12	T-ALL	0.99916	0.00084	T-ALL
T-ALL-C13	T-ALL	0.76418	0.23582	T-ALL
T-ALL-C14	T-ALL	0.14795	0.85205	other
T-ALL-C15 (testset)	T-ALL	0.97798	0.02202	T-ALL
T-ALL-C16 (testset)	T-ALL	0.28737	0.71263	other
T-ALL-C17	T-ALL	0.95168	0.04832	T-ALL
T-ALL-C18	T-ALL	0.99433	0.00567	T-ALL
T-ALL-C19	T-ALL	0.97603	0.02397	T-ALL
T-ALL-C1	T-ALL	0.56237	0.43763	T-ALL
T-ALL-C20	T-ALL	0.97208	0.02792	T-ALL
T-ALL-C21	T-ALL	0.99797	0.00203	T-ALL
T-ALL-C22 (testset)	T-ALL	0.65484	0.34516	T-ALL
T-ALL-C23	T-ALL	0.62904	0.37096	T-ALL
T-ALL-C24 (testset)	T-ALL	0.73499	0.26501	T-ALL
T-ALL-C25 (testset)	T-ALL	0.90441	0.09559	T-ALL
T-ALL-C26	T-ALL	0.24498	0.75502	other
T-ALL-C2	T-ALL	0.94678	0.05322	T-ALL
T-ALL-C3	T-ALL	0.93066	0.06934	T-ALL
T-ALL-C4	T-ALL	0.62329	0.37671	T-ALL
T-ALL-C5 (testset)	T-ALL	0.24002	0.75998	other
T-ALL-C6	T-ALL	0.92926	0.07074	T-ALL
T-ALL-C7 (testset)	T-ALL	0.99588	0.00412	T-ALL
T-ALL-C8	T-ALL	0.09578	0.90422	other
T-ALL-C9	T-ALL	0.60437	0.39563	T-ALL
T-ALL-R1	T-ALL	0.823	0.177	T-ALL
T-ALL-R2	T-ALL	0.9991	9e-04	T-ALL
T-ALL-R3	T-ALL	0.95363	0.04637	T-ALL
T-ALL-R4	T-ALL	0.94168	0.05832	T-ALL
T-ALL-R5	T-ALL	0.98316	0.01684	T-ALL
T-ALL-R6	T-ALL	0.39102	0.60898	other
TEL-AML1-10	other	0.05	0.95	other
TEL-AML1-11 (testset)	other	0.01442	0.98558	other
TEL-AML1-12	other	0.01761	0.98239	other
TEL-AML1-13 (testset)	other	0.00591	0.99409	other
TEL-AML1-14	other	0.01717	0.98283	other
TEL-AML1-1	other	0.00886	0.99114	other
TEL-AML1-2	other	0.02308	0.97692	other
TEL-AML1-3	other	0.05065	0.94935	other
TEL-AML1-4	other	0.01654	0.98346	other
TEL-AML1-5 (testset)	other	0.04649	0.95351	other
TEL-AML1-6	other	0.00505	0.99495	other
TEL-AML1-7	other	0.00641	0.99359	other
TEL-AML1-8 (testset)	other	0.01534	0.98466	other
TEL-AML1-9	other	0.01807	0.98193	other
TEL-AML1-2M1 (testset)	other	0.02491	0.97509	other
TEL-AML1-2M2	other	0.00651	0.99349	other
TEL-AML1-2M3	other	0.00542	0.99458	other
TEL-AML1-2M4 (testset)	other	0.01938	0.98062	other
TEL-AML1-2M5	other	0.00627	0.99373	other
TEL-AML1-C10	other	0.014	0.986	other
TEL-AML1-C11	other	0.01217	0.98783	other
TEL-AML1-C12	other	0.00622	0.99378	other
TEL-AML1-C13	other	0.02635	0.97365	other
TEL-AML1-C14 (testset)	other	0.02879	0.97121	other
TEL-AML1-C15	other	0.02193	0.97807	other
TEL-AML1-C16	other	0.00471	0.99529	other
TEL-AML1-C17	other	0.00741	0.99259	other
TEL-AML1-C18	other	0.00947	0.99053	other
TEL-AML1-C19 (testset)	other	0.00242	0.99758	other
TEL-AML1-C1 (testset)	other	0.04145	0.95855	other
TEL-AML1-C20 (testset)	other	0.00473	0.99527	other
TEL-AML1-C21	other	0.00955	0.99045	other
TEL-AML1-C22	other	0.00886	0.99114	other
TEL-AML1-C23 (testset)	other	0.01649	0.98351	other
TEL-AML1-C24	other	0.0428	0.9572	other
TEL-AML1-C25	other	0.01977	0.98023	other
TEL-AML1-C26 (testset)	other	0.00345	0.99655	other
TEL-AML1-C27	other	0.00258	0.99742	other
TEL-AML1-C28 (testset)	other	0.03304	0.96696	other
TEL-AML1-C29	other	0.01427	0.98573	other
TEL-AML1-C2	other	0.00326	0.99674	other
TEL-AML1-C30	other	0.05895	0.94105	other
TEL-AML1-C31 (testset)	other	0.00348	0.99652	other
TEL-AML1-C32	other	0.01358	0.98642	other
TEL-AML1-C33 (testset)	other	0.00263	0.99737	other
TEL-AML1-C34	other	0.00953	0.99047	other
TEL-AML1-C35	other	0.01402	0.98598	other
TEL-AML1-C36 (testset)	other	0.01341	0.98659	other
TEL-AML1-C37	other	0.00884	0.99116	other
TEL-AML1-C38	other	0.04939	0.95061	other
TEL-AML1-C39	other	0.01614	0.98386	other
TEL-AML1-C3	other	0.00313	0.99687	other
TEL-AML1-C40	other	0.0144	0.9856	other
TEL-AML1-C41	other	0.01912	0.98088	other
TEL-AML1-C42	other	0.02417	0.97583	other
TEL-AML1-C43	other	0.00958	0.99042	other
TEL-AML1-C44	other	0.00456	0.99544	other
TEL-AML1-C45	other	0.00585	0.99415	other
TEL-AML1-C46	other	0.00495	0.99505	other
TEL-AML1-C47	other	0.0103	0.9897	other
TEL-AML1-C48	other	0.12071	0.87929	other
TEL-AML1-C49 (testset)	other	0.0075	0.9925	other
TEL-AML1-C4 (testset)	other	0.00955	0.99045	other
TEL-AML1-C50	other	0.01229	0.98771	other
TEL-AML1-C51 (testset)	other	0.01068	0.98932	other
TEL-AML1-C52	other	0.0244	0.9756	other
TEL-AML1-C53 (testset)	other	0.06798	0.93202	other
TEL-AML1-C54	other	0.00916	0.99084	other
TEL-AML1-C55 (testset)	other	0.01668	0.98332	other
TEL-AML1-C56	other	0.01023	0.98977	other
TEL-AML1-C57	other	0.02341	0.97659	other
TEL-AML1-C5 (testset)	other	0.01916	0.98084	other
TEL-AML1-C6	other	0.02298	0.97702	other
TEL-AML1-C7	other	0.01043	0.98957	other
TEL-AML1-C8	other	0.00319	0.99681	other
TEL-AML1-C9	other	0.04855	0.95145	other
TEL-AML1-R1 (testset)	other	0.01605	0.98395	other
TEL-AML1-R2 (testset)	other	0.02421	0.97579	other
TEL-AML1-R3	other	0.00836	0.99164	other