GO:0006952

GO:0006952

defense response (annotated genes)

Biological Process

Parent node

GO:0006952	defense response

This leaf node contains 76 genes

The following 45 of these are used in classification:

	Symbol	Genename	T-ALL score	other score
38017_at	CD79A	CD79A antigen (immunoglobulin-associated alpha)	-2.2382	0.3434
38018_g_at	CD79A	CD79A antigen (immunoglobulin-associated alpha)	-1.6396	0.2516
38893_at	NCF4	neutrophil cytosolic factor 4, 40kDa	-1.5905	0.244
40511_at	GATA3	GATA binding protein 3	1.482	-0.2274
38894_g_at	NCF4	neutrophil cytosolic factor 4, 40kDa	-1.3567	0.2082
38895_i_at	NCF4	neutrophil cytosolic factor 4, 40kDa	-0.9384	0.144
39020_at	SIVA	CD27-binding (Siva) protein	0.8777	-0.1347
35764_at	OFD1	oral-facial-digital syndrome 1	-0.8149	0.125
33320_at	HCP5	HLA complex P5	-0.4721	0.0724
38575_at	MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	-0.3481	0.0534
37127_at	NALP1	NACHT, leucine rich repeat and PYD containing 1	-0.3185	0.0489
37536_at	CD83	CD83 antigen (activated B lymphocytes, immunoglobulin superfamily)	0.3124	-0.0479
38006_at	CD48	CD48 antigen (B-cell membrane protein)	0.2987	-0.0458
32350_at	MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	-0.298	0.0457
41763_g_at	TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	0.2697	-0.0414
41106_at	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	0.2359	-0.0362
41762_at	TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	0.1876	-0.0288
31787_at	CAMLG	calcium modulating ligand	0.1513	-0.0232
32825_at	HRMT1L2	HMT1 hnRNP methyltransferase-like 2 (S. cerevisiae)	0.1471	-0.0226
1770_at	IFNA2	interferon, alpha 2	0.1416	-0.0217
38964_r_at	WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	-0.1295	0.0199
37719_at	MLF2	myeloid leukemia factor 2	0.1274	-0.0195
32070_at	PTPRCAP	protein tyrosine phosphatase, receptor type, C-associated protein	0.1252	-0.0192
34223_at	CSF3R	colony stimulating factor 3 receptor (granulocyte)	-0.1162	0.0178
41761_at	TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	0.1019	-0.0156
33489_at	TFF2	trefoil factor 2 (spasmolytic protein 1)	-0.0982	0.0151
38233_at	HOMER3	homer homolog 3 (Drosophila)	0.0969	-0.0149
37645_at	CD69	CD69 antigen (p60, early T-cell activation antigen)	-0.0724	0.0111
40357_at	INHBA	inhibin, beta A (activin A, activin AB alpha polypeptide)	0.0678	-0.0104
33208_at	DNAJC3	DnaJ (Hsp40) homolog, subfamily C, member 3	0.0659	-0.0101
1540_f_at	IFNA5	interferon, alpha 5	-0.0599	0.0092
38963_i_at	WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	-0.0572	0.0088
38545_at	INHBB	inhibin, beta B (activin AB beta polypeptide)	-0.057	0.0087
37360_at	LY6E	lymphocyte antigen 6 complex, locus E	-0.0552	0.0085
38672_at	PPP1R10	protein phosphatase 1, regulatory subunit 10	-0.0534	0.0082
427_f_at	IFNA10	interferon, alpha 10	0.0406	-0.0062
596_s_at	CSF3R	colony stimulating factor 3 receptor (granulocyte)	-0.0348	0.0053
38180_f_at	PSG9	pregnancy specific beta-1-glycoprotein 9	-0.0335	0.0051
1100_at	IRAK1	interleukin-1 receptor-associated kinase 1	-0.0269	0.0041
31980_at	FOXN1	forkhead box N1	-0.0228	0.0035
34660_at	RNASE6	ribonuclease, RNase A family, k6	-0.0209	0.0032
1580_f_at	IFNA4	interferon, alpha 4	-0.0075	0.0011
37856_at	CD84	CD84 antigen (leukocyte antigen)	0.0055	-8e-04
37898_r_at	TFF3	trefoil factor 3 (intestinal)	-0.0022	3e-04
35552_at	PCYT1B	phosphate cytidylyltransferase 1, choline, beta isoform	0.001	-1e-04

Performance on training data

• Error rate: 0.01376
• Performance: 0.05663
• Redundancy: 6.39543

	Sensitivity	Specificity
T-ALL	1	0.98413
other	0.98413	1

Performance on test data

• Error rate: 0.00917
• Performance: 0.04775
• Redundancy: 6.43501

	Sensitivity	Specificity
T-ALL	0.92857	1
other	1	0.92857

Predictions

	Class	T-ALL	other	Predictionn
BCR-ABL-1	other	0.41589	0.58411	other
BCR-ABL-2	other	0	1	other
BCR-ABL-3 (testset)	other	0	1	other
BCR-ABL-4	other	0	1	other
BCR-ABL-5	other	0	1	other
BCR-ABL-6 (testset)	other	0.00385	0.99615	other
BCR-ABL-7 (testset)	other	0	1	other
BCR-ABL-8 (testset)	other	0	1	other
BCR-ABL-9 (testset)	other	2e-05	0.99998	other
BCR-ABL-C1 (testset)	other	0.00865	0.99135	other
BCR-ABL-Hyperdip-10 (testset)	other	0	1	other
BCR-ABL-Hyperdip-R5	other	0	1	other
BCR-ABL-R1	other	0.00012	0.99988	other
BCR-ABL-R2	other	7e-04	0.9993	other
BCR-ABL-R3 (testset)	other	0	1	other
E2A-PBX1-10	other	0.00057	0.99943	other
E2A-PBX1-11	other	6e-05	0.99994	other
E2A-PBX1-12 (testset)	other	0.01236	0.98764	other
E2A-PBX1-13	other	0	1	other
E2A-PBX1-1	other	0	1	other
E2A-PBX1-2	other	0	1	other
E2A-PBX1-3	other	0	1	other
E2A-PBX1-4 (testset)	other	0.00017	0.99983	other
E2A-PBX1-5	other	0.0013	0.9987	other
E2A-PBX1-6	other	2e-05	0.99998	other
E2A-PBX1-7	other	0	1	other
E2A-PBX1-8	other	0	1	other
E2A-PBX1-9	other	0	1	other
E2A-PBX1-2M1	other	0	1	other
E2A-PBX1-C10	other	0	1	other
E2A-PBX1-C11	other	0.01218	0.98782	other
E2A-PBX1-C12	other	0	1	other
E2A-PBX1-C1	other	0.00097	0.99903	other
E2A-PBX1-C2	other	0.00014	0.99986	other
E2A-PBX1-C3 (testset)	other	2e-05	0.99998	other
E2A-PBX1-C4	other	0	1	other
E2A-PBX1-C5 (testset)	other	7e-05	0.99993	other
E2A-PBX1-C6	other	0.00042	0.99958	other
E2A-PBX1-C7	other	0	1	other
E2A-PBX1-C8	other	0	1	other
E2A-PBX1-C9	other	3e-05	0.99997	other
E2A-PBX1-R1	other	2e-04	0.9998	other
Hyperdip-50-10	other	0	1	other
Hyperdip-50-11 (testset)	other	0	1	other
Hyperdip-50-12	other	0	1	other
Hyperdip-50-13 (testset)	other	4e-05	0.99996	other
Hyperdip-50-14	other	0	1	other
Hyperdip-50-1	other	7e-04	0.9993	other
Hyperdip-50-2	other	0	1	other
Hyperdip-50-3 (testset)	other	0	1	other
Hyperdip-50-4 (testset)	other	0.00097	0.99903	other
Hyperdip-50-5 (testset)	other	1e-05	0.99999	other
Hyperdip-50-6	other	0	1	other
Hyperdip-50-7	other	0.79827	0.20173	T-ALL
Hyperdip-50-8 (testset)	other	0	1	other
Hyperdip-50-9	other	0	1	other
Hyperdip-50-2M1	other	6e-05	0.99994	other
Hyperdip-50-2M2 (testset)	other	0.00119	0.99881	other
Hyperdip-50-C10	other	0	1	other
Hyperdip-50-C11 (testset)	other	0	1	other
Hyperdip-50-C12	other	5e-05	0.99995	other
Hyperdip-50-C13	other	1e-05	0.99999	other
Hyperdip-50-C14	other	0	1	other
Hyperdip-50-C15	other	0	1	other
Hyperdip-50-C16	other	6e-05	0.99994	other
Hyperdip-50-C17	other	0	1	other
Hyperdip-50-C18	other	0	1	other
Hyperdip-50-C19 (testset)	other	1e-05	0.99999	other
Hyperdip-50-C1	other	0	1	other
Hyperdip-50-C20	other	1e-05	0.99999	other
Hyperdip-50-C21	other	1e-05	0.99999	other
Hyperdip-50-C22 (testset)	other	0	1	other
Hyperdip-50-C23	other	0	1	other
Hyperdip-50-C24	other	2e-05	0.99998	other
Hyperdip-50-C25	other	0	1	other
Hyperdip-50-C26	other	0	1	other
Hyperdip-50-C27-N	other	0.00148	0.99852	other
Hyperdip-50-C28	other	0.00296	0.99704	other
Hyperdip-50-C29 (testset)	other	3e-05	0.99997	other
Hyperdip-50-C2 (testset)	other	2e-05	0.99998	other
Hyperdip-50-C30	other	0	1	other
Hyperdip-50-C31	other	0	1	other
Hyperdip-50-C32	other	0	1	other
Hyperdip-50-C33	other	0.0012	0.9988	other
Hyperdip-50-C34	other	0	1	other
Hyperdip-50-C35 (testset)	other	7e-05	0.99993	other
Hyperdip-50-C36	other	0	1	other
Hyperdip-50-C37	other	0.00011	0.99989	other
Hyperdip-50-C38	other	0	1	other
Hyperdip-50-C39 (testset)	other	0	1	other
Hyperdip-50-C3	other	0.00462	0.99538	other
Hyperdip-50-C40	other	0.00058	0.99942	other
Hyperdip-50-C41 (testset)	other	0	1	other
Hyperdip-50-C42 (testset)	other	0	1	other
Hyperdip-50-C43	other	0	1	other
Hyperdip-50-C4	other	0.00231	0.99769	other
Hyperdip-50-C5 (testset)	other	0	1	other
Hyperdip-50-C6	other	0	1	other
Hyperdip-50-C7 (testset)	other	0	1	other
Hyperdip-50-C8 (testset)	other	4e-05	0.99996	other
Hyperdip-50-C9	other	4e-05	0.99996	other
Hyperdip-50-R1	other	9e-05	0.99991	other
Hyperdip-50-R2 (testset)	other	2e-05	0.99998	other
Hyperdip-50-R3	other	0.5942	0.4058	T-ALL
Hyperdip-50-R4	other	0	1	other
Hyperdip-50-R5 (testset)	other	1e-05	0.99999	other
Hyperdip47-50-1	other	0	1	other
Hyperdip47-50-2	other	0	1	other
Hyperdip47-50-3 (testset)	other	0	1	other
Hyperdip47-50-2M1 (testset)	other	0	1	other
Hyperdip47-50-C10 (testset)	other	0	1	other
Hyperdip47-50-C11	other	0.00062	0.99938	other
Hyperdip47-50-C12	other	1e-05	0.99999	other
Hyperdip47-50-C13	other	6e-05	0.99994	other
Hyperdip47-50-C14-N (testset)	other	0	1	other
Hyperdip47-50-C15 (testset)	other	0	1	other
Hyperdip47-50-C16	other	0.00018	0.99982	other
Hyperdip47-50-C17	other	0	1	other
Hyperdip47-50-C18	other	0	1	other
Hyperdip47-50-C19	other	0.01253	0.98747	other
Hyperdip47-50-C1 (testset)	other	0.00304	0.99696	other
Hyperdip47-50-C2 (testset)	other	0	1	other
Hyperdip47-50-C3-N (testset)	other	0	1	other
Hyperdip47-50-C4	other	1e-05	0.99999	other
Hyperdip47-50-C5 (testset)	other	0	1	other
Hyperdip47-50-C6 (testset)	other	0	1	other
Hyperdip47-50-C7	other	0.00216	0.99784	other
Hyperdip47-50-C8	other	0	1	other
Hyperdip47-50-C9	other	0	1	other
Hypodip-1 (testset)	other	0	1	other
Hypodip-2	other	0	1	other
Hypodip-2M1 (testset)	other	0	1	other
Hypodip-C1	other	0	1	other
Hypodip-C2 (testset)	other	2e-05	0.99998	other
Hypodip-C3	other	0	1	other
Hypodip-C4	other	7e-04	0.9993	other
Hypodip-C5	other	0	1	other
Hypodip-C6 (testset)	other	0	1	other
MLL-1 (testset)	other	1e-05	0.99999	other
MLL-2	other	0.02483	0.97517	other
MLL-3 (testset)	other	0	1	other
MLL-4	other	0	1	other
MLL-5 (testset)	other	0	1	other
MLL-6 (testset)	other	1e-05	0.99999	other
MLL-7	other	0	1	other
MLL-8 (testset)	other	0.00169	0.99831	other
MLL-2M1	other	1e-05	0.99999	other
MLL-2M2 (testset)	other	4e-05	0.99996	other
MLL-C1	other	0	1	other
MLL-C2	other	0	1	other
MLL-C3 (testset)	other	1e-05	0.99999	other
MLL-C4	other	0.00154	0.99846	other
MLL-C5	other	0	1	other
MLL-C6	other	0	1	other
MLL-R1 (testset)	other	0.01866	0.98134	other
MLL-R2	other	0.00048	0.99952	other
MLL-R3	other	0	1	other
MLL-R4	other	0	1	other
Normal-1	other	2e-05	0.99998	other
Normal-2	other	0	1	other
Normal-3	other	4e-05	0.99996	other
Normal-C1-N	other	0	1	other
Normal-C10	other	1e-05	0.99999	other
Normal-C11-N (testset)	other	2e-05	0.99998	other
Normal-C12 (testset)	other	0.03314	0.96686	other
Normal-C2-N	other	0	1	other
Normal-C3-N	other	0.03454	0.96546	other
Normal-C4-N	other	1e-05	0.99999	other
Normal-C5	other	0.00029	0.99971	other
Normal-C6 (testset)	other	5e-05	0.99995	other
Normal-C7-N (testset)	other	0.02359	0.97641	other
Normal-C8	other	0	1	other
Normal-C9 (testset)	other	0	1	other
Normal-R1 (testset)	other	0	1	other
Normal-R2-N	other	0	1	other
Normal-R3	other	0.28278	0.71722	other
Pseudodip-1	other	0	1	other
Pseudodip-2	other	0	1	other
Pseudodip-3	other	0	1	other
Pseudodip-4 (testset)	other	0	1	other
Pseudodip-5 (testset)	other	0	1	other
Pseudodip-6 (testset)	other	0	1	other
Pseudodip-7	other	0	1	other
Pseudodip-8-N	other	0	1	other
Pseudodip-9	other	1e-05	0.99999	other
Pseudodip-C10 (testset)	other	0	1	other
Pseudodip-C11 (testset)	other	0	1	other
Pseudodip-C12 (testset)	other	0	1	other
Pseudodip-C13	other	0	1	other
Pseudodip-C14 (testset)	other	0	1	other
Pseudodip-C15	other	0.00061	0.99939	other
Pseudodip-C16-N (testset)	other	1e-05	0.99999	other
Pseudodip-C17	other	0	1	other
Pseudodip-C18	other	0.03456	0.96544	other
Pseudodip-C19	other	0.01651	0.98349	other
Pseudodip-C1	other	0.04922	0.95078	other
Pseudodip-C2-N	other	0.0158	0.9842	other
Pseudodip-C3	other	1e-05	0.99999	other
Pseudodip-C4	other	0.8908	0.1092	T-ALL
Pseudodip-C5 (testset)	other	0	1	other
Pseudodip-C6	other	0	1	other
Pseudodip-C7	other	0	1	other
Pseudodip-C8	other	0	1	other
Pseudodip-C9	other	1e-05	0.99999	other
Pseudodip-R1-N (testset)	other	0	1	other
T-ALL-10 (testset)	T-ALL	1	0	T-ALL
T-ALL-1 (testset)	T-ALL	1	0	T-ALL
T-ALL-2 (testset)	T-ALL	0.99884	0.00116	T-ALL
T-ALL-3	T-ALL	0.99997	3e-05	T-ALL
T-ALL-4 (testset)	T-ALL	0.9999	1e-04	T-ALL
T-ALL-5 (testset)	T-ALL	1	0	T-ALL
T-ALL-6	T-ALL	1	0	T-ALL
T-ALL-7 (testset)	T-ALL	1	0	T-ALL
T-ALL-8 (testset)	T-ALL	0.99999	1e-05	T-ALL
T-ALL-9	T-ALL	0.87662	0.12338	T-ALL
T-ALL-2M1	T-ALL	1	0	T-ALL
T-ALL-C10	T-ALL	1	0	T-ALL
T-ALL-C11	T-ALL	1	0	T-ALL
T-ALL-C12	T-ALL	1	0	T-ALL
T-ALL-C13	T-ALL	0.99996	4e-05	T-ALL
T-ALL-C14	T-ALL	0.99972	0.00028	T-ALL
T-ALL-C15 (testset)	T-ALL	1	0	T-ALL
T-ALL-C16 (testset)	T-ALL	0.99983	0.00017	T-ALL
T-ALL-C17	T-ALL	0.99986	0.00014	T-ALL
T-ALL-C18	T-ALL	0.91688	0.08312	T-ALL
T-ALL-C19	T-ALL	1	0	T-ALL
T-ALL-C1	T-ALL	0.9998	2e-04	T-ALL
T-ALL-C20	T-ALL	1	0	T-ALL
T-ALL-C21	T-ALL	0.99953	0.00047	T-ALL
T-ALL-C22 (testset)	T-ALL	0.99999	1e-05	T-ALL
T-ALL-C23	T-ALL	0.99877	0.00123	T-ALL
T-ALL-C24 (testset)	T-ALL	1	0	T-ALL
T-ALL-C25 (testset)	T-ALL	1	0	T-ALL
T-ALL-C26	T-ALL	0.99999	1e-05	T-ALL
T-ALL-C2	T-ALL	0.99999	1e-05	T-ALL
T-ALL-C3	T-ALL	1	0	T-ALL
T-ALL-C4	T-ALL	0.99999	1e-05	T-ALL
T-ALL-C5 (testset)	T-ALL	0.81532	0.18468	T-ALL
T-ALL-C6	T-ALL	1	0	T-ALL
T-ALL-C7 (testset)	T-ALL	0.11055	0.88945	other
T-ALL-C8	T-ALL	0.99991	9e-05	T-ALL
T-ALL-C9	T-ALL	1	0	T-ALL
T-ALL-R1	T-ALL	0.99997	3e-05	T-ALL
T-ALL-R2	T-ALL	0.99999	1e-05	T-ALL
T-ALL-R3	T-ALL	0.99998	2e-05	T-ALL
T-ALL-R4	T-ALL	1	0	T-ALL
T-ALL-R5	T-ALL	0.99871	0.00129	T-ALL
T-ALL-R6	T-ALL	0.99029	0.00971	T-ALL
TEL-AML1-10	other	0	1	other
TEL-AML1-11 (testset)	other	0	1	other
TEL-AML1-12	other	0	1	other
TEL-AML1-13 (testset)	other	0	1	other
TEL-AML1-14	other	0	1	other
TEL-AML1-1	other	0.00099	0.99901	other
TEL-AML1-2	other	0	1	other
TEL-AML1-3	other	0	1	other
TEL-AML1-4	other	0	1	other
TEL-AML1-5 (testset)	other	8e-05	0.99992	other
TEL-AML1-6	other	0	1	other
TEL-AML1-7	other	0	1	other
TEL-AML1-8 (testset)	other	0	1	other
TEL-AML1-9	other	0	1	other
TEL-AML1-2M1 (testset)	other	0	1	other
TEL-AML1-2M2	other	0	1	other
TEL-AML1-2M3	other	0.00012	0.99988	other
TEL-AML1-2M4 (testset)	other	1e-05	0.99999	other
TEL-AML1-2M5	other	0	1	other
TEL-AML1-C10	other	2e-05	0.99998	other
TEL-AML1-C11	other	0	1	other
TEL-AML1-C12	other	0	1	other
TEL-AML1-C13	other	0	1	other
TEL-AML1-C14 (testset)	other	0	1	other
TEL-AML1-C15	other	0	1	other
TEL-AML1-C16	other	0	1	other
TEL-AML1-C17	other	0.00021	0.99979	other
TEL-AML1-C18	other	0	1	other
TEL-AML1-C19 (testset)	other	0	1	other
TEL-AML1-C1 (testset)	other	0	1	other
TEL-AML1-C20 (testset)	other	0	1	other
TEL-AML1-C21	other	0.02609	0.97391	other
TEL-AML1-C22	other	0	1	other
TEL-AML1-C23 (testset)	other	1e-05	0.99999	other
TEL-AML1-C24	other	0	1	other
TEL-AML1-C25	other	0	1	other
TEL-AML1-C26 (testset)	other	0	1	other
TEL-AML1-C27	other	0	1	other
TEL-AML1-C28 (testset)	other	0	1	other
TEL-AML1-C29	other	0	1	other
TEL-AML1-C2	other	0	1	other
TEL-AML1-C30	other	0	1	other
TEL-AML1-C31 (testset)	other	0	1	other
TEL-AML1-C32	other	0	1	other
TEL-AML1-C33 (testset)	other	0	1	other
TEL-AML1-C34	other	0	1	other
TEL-AML1-C35	other	2e-05	0.99998	other
TEL-AML1-C36 (testset)	other	0	1	other
TEL-AML1-C37	other	0	1	other
TEL-AML1-C38	other	0	1	other
TEL-AML1-C39	other	0	1	other
TEL-AML1-C3	other	0	1	other
TEL-AML1-C40	other	0	1	other
TEL-AML1-C41	other	0.00014	0.99986	other
TEL-AML1-C42	other	0.00011	0.99989	other
TEL-AML1-C43	other	0	1	other
TEL-AML1-C44	other	0	1	other
TEL-AML1-C45	other	0	1	other
TEL-AML1-C46	other	0	1	other
TEL-AML1-C47	other	0	1	other
TEL-AML1-C48	other	0	1	other
TEL-AML1-C49 (testset)	other	0.00018	0.99982	other
TEL-AML1-C4 (testset)	other	0	1	other
TEL-AML1-C50	other	0	1	other
TEL-AML1-C51 (testset)	other	0	1	other
TEL-AML1-C52	other	0	1	other
TEL-AML1-C53 (testset)	other	3e-05	0.99997	other
TEL-AML1-C54	other	0	1	other
TEL-AML1-C55 (testset)	other	0	1	other
TEL-AML1-C56	other	2e-05	0.99998	other
TEL-AML1-C57	other	2e-05	0.99998	other
TEL-AML1-C5 (testset)	other	1e-05	0.99999	other
TEL-AML1-C6	other	0	1	other
TEL-AML1-C7	other	0	1	other
TEL-AML1-C8	other	0.09153	0.90847	other
TEL-AML1-C9	other	1e-04	0.9999	other
TEL-AML1-R1 (testset)	other	0	1	other
TEL-AML1-R2 (testset)	other	0	1	other
TEL-AML1-R3	other	0	1	other