GO:0006915


GO:0006915

apoptosis
(annotated genes)

Biological
Process

Parent node

This leaf node contains 200 genes

The following 47 of these are used in classification:

 SymbolGenenameT-ALL scoreother score
649_s_atCXCR4 chemokine (C-X-C motif) receptor 4-0.92420.1418
39402_atIL1B interleukin 1, beta-0.71590.1099
39020_atSIVA CD27-binding (Siva) protein0.7021-0.1077
1520_s_atIL1B interleukin 1, beta-0.69550.1067
38114_atRAD21 RAD21 homolog (S. pombe)0.6128-0.094
41193_atDUSP6 dual specificity phosphatase 6-0.55990.0859
1461_atNFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha-0.55860.0857
36143_atCASP3 caspase 3, apoptosis-related cysteine protease0.4785-0.0734
35869_atLY86 lymphocyte antigen 86-0.44780.0687
33535_atP2RX1 purinergic receptor P2X, ligand-gated ion channel, 1-0.39470.0606
33804_atPTK2B PTK2B protein tyrosine kinase 2 beta-0.37260.0572
37384_atPPM1F protein phosphatase 1F (PP2C domain containing)-0.34820.0534
32114_s_atADORA2A adenosine A2a receptor0.3223-0.0495
38977_atYARS tyrosyl-tRNA synthetase0.2743-0.0421
38823_s_atSTK17A serine/threonine kinase 17a (apoptosis-inducing)0.2632-0.0404
2009_atPTK2B PTK2B protein tyrosine kinase 2 beta-0.25510.0391
37829_atGAS2 growth arrest-specific 20.236-0.0362
36275_atSEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A-0.21370.0328
39691_atSH3GLB1 SH3-domain GRB2-like endophilin B10.1963-0.0301
40049_atDAPK1 death-associated protein kinase 10.1816-0.0279
794_atPTPN6 protein tyrosine phosphatase, non-receptor type 60.1673-0.0257
36564_atYARS tyrosyl-tRNA synthetase-0.15030.0231
38822_atSTK17A serine/threonine kinase 17a (apoptosis-inducing)0.1472-0.0226
40516_atAHR aryl hydrocarbon receptor0.1289-0.0198
37028_atPPP1R15A protein phosphatase 1, regulatory (inhibitor) subunit 15A-0.12520.0192
35662_atCASP6 caspase 6, apoptosis-related cysteine protease0.1183-0.0182
33813_atTNFRSF1B tumor necrosis factor receptor superfamily, member 1B-0.10640.0163
1583_atTNFRSF1B tumor necrosis factor receptor superfamily, member 1B-0.10340.0159
41763_g_atTIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 10.1021-0.0157
1356_atDAP3 death associated protein 30.0968-0.0149
38804_atCSE1L CSE1 chromosome segregation 1-like (yeast)0.0933-0.0143
34397_atOA48-18 acid-inducible phosphoprotein0.0875-0.0134
35238_atTRAF5 TNF receptor-associated factor 50.0837-0.0128
1974_s_atTP53 tumor protein p53 (Li-Fraumeni syndrome)-0.08180.0126
1715_atTNFSF10 tumor necrosis factor (ligand) superfamily, member 100.0676-0.0104
1729_atTRADD TNFRSF1A-associated via death domain0.0648-0.0099
33989_f_atTEGT testis enhanced gene transcript (BAX inhibitor 1)-0.06090.0093
1673_atNGFR nerve growth factor receptor (TNFR superfamily, member 16)-0.05670.0087
34937_atDFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)0.0525-0.0081
35150_atTNFRSF5 tumor necrosis factor receptor superfamily, member 5-0.04810.0074
35402_atTNFRSF21 tumor necrosis factor receptor superfamily, member 21-0.03660.0056
33299_atCDC2L2 cell division cycle 2-like 2-0.03640.0056
40757_atGZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)0.0263-0.004
41762_atTIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 10.0192-0.003
35149_atTNFRSF5 tumor necrosis factor receptor superfamily, member 5-0.01490.0023
34767_atMOAP1 modulator of apoptosis 10.0101-0.0016
36661_s_atCD14 CD14 antigen0.0088-0.0013

Performance on training data

 SensitivitySpecificity
T-ALL10.99471
other0.994711

Performance on test data

 SensitivitySpecificity
T-ALL0.928570.98947
other0.989470.92857

Predictions

 ClassT-ALLotherPredictionn
BCR-ABL-1other0.001320.99868 other
BCR-ABL-2other0.000660.99934 other
BCR-ABL-3 (testset)other0.009690.99031 other
BCR-ABL-4other6e-050.99994 other
BCR-ABL-5other0.000750.99925 other
BCR-ABL-6 (testset)other0.002830.99717 other
BCR-ABL-7 (testset)other0.007850.99215 other
BCR-ABL-8 (testset)other0.004860.99514 other
BCR-ABL-9 (testset)other0.001410.99859 other
BCR-ABL-C1 (testset)other0.017040.98296 other
BCR-ABL-Hyperdip-10 (testset)other1e-040.9999 other
BCR-ABL-Hyperdip-R5other2e-050.99998 other
BCR-ABL-R1other0.159620.84038 other
BCR-ABL-R2other0.000570.99943 other
BCR-ABL-R3 (testset)other0.010840.98916 other
E2A-PBX1-10other0.001690.99831 other
E2A-PBX1-11other0.005240.99476 other
E2A-PBX1-12 (testset)other0.006630.99337 other
E2A-PBX1-13other0.004270.99573 other
E2A-PBX1-1other0.000220.99978 other
E2A-PBX1-2other0.028240.97176 other
E2A-PBX1-3other0.00240.9976 other
E2A-PBX1-4 (testset)other0.011530.98847 other
E2A-PBX1-5other0.000840.99916 other
E2A-PBX1-6other0.005930.99407 other
E2A-PBX1-7other0.002580.99742 other
E2A-PBX1-8other0.006640.99336 other
E2A-PBX1-9other0.017760.98224 other
E2A-PBX1-2M1other0.003870.99613 other
E2A-PBX1-C10other0.000520.99948 other
E2A-PBX1-C11other0.127640.87236 other
E2A-PBX1-C12other0.009440.99056 other
E2A-PBX1-C1other0.001110.99889 other
E2A-PBX1-C2other0.003140.99686 other
E2A-PBX1-C3 (testset)other0.001890.99811 other
E2A-PBX1-C4other0.001050.99895 other
E2A-PBX1-C5 (testset)other0.004530.99547 other
E2A-PBX1-C6other0.001930.99807 other
E2A-PBX1-C7other0.005090.99491 other
E2A-PBX1-C8other0.53710.4629 T-ALL
E2A-PBX1-C9other0.014490.98551 other
E2A-PBX1-R1other0.001220.99878 other
Hyperdip-50-10other0.000350.99965 other
Hyperdip-50-11 (testset)other0.002580.99742 other
Hyperdip-50-12other8e-050.99992 other
Hyperdip-50-13 (testset)other0.000480.99952 other
Hyperdip-50-14other6e-050.99994 other
Hyperdip-50-1other0.0110.989 other
Hyperdip-50-2other0.000570.99943 other
Hyperdip-50-3 (testset)other1e-040.9999 other
Hyperdip-50-4 (testset)other0.000120.99988 other
Hyperdip-50-5 (testset)other0.000110.99989 other
Hyperdip-50-6other3e-050.99997 other
Hyperdip-50-7other0.015350.98465 other
Hyperdip-50-8 (testset)other0.000270.99973 other
Hyperdip-50-9other0.000180.99982 other
Hyperdip-50-2M1other0.000620.99938 other
Hyperdip-50-2M2 (testset)other0.027550.97245 other
Hyperdip-50-C10other0.003310.99669 other
Hyperdip-50-C11 (testset)other0.000250.99975 other
Hyperdip-50-C12other0.005150.99485 other
Hyperdip-50-C13other0.000780.99922 other
Hyperdip-50-C14other0.000360.99964 other
Hyperdip-50-C15other0.001880.99812 other
Hyperdip-50-C16other0.009030.99097 other
Hyperdip-50-C17other6e-050.99994 other
Hyperdip-50-C18other0.001140.99886 other
Hyperdip-50-C19 (testset)other0.001930.99807 other
Hyperdip-50-C1other0.002740.99726 other
Hyperdip-50-C20other0.001550.99845 other
Hyperdip-50-C21other01 other
Hyperdip-50-C22 (testset)other0.001540.99846 other
Hyperdip-50-C23other0.000730.99927 other
Hyperdip-50-C24other6e-040.9994 other
Hyperdip-50-C25other0.000280.99972 other
Hyperdip-50-C26other0.00120.9988 other
Hyperdip-50-C27-Nother0.020170.97983 other
Hyperdip-50-C28other0.001550.99845 other
Hyperdip-50-C29 (testset)other0.058370.94163 other
Hyperdip-50-C2 (testset)other4e-040.9996 other
Hyperdip-50-C30other8e-050.99992 other
Hyperdip-50-C31other1e-050.99999 other
Hyperdip-50-C32other01 other
Hyperdip-50-C33other0.01280.9872 other
Hyperdip-50-C34other0.00380.9962 other
Hyperdip-50-C35 (testset)other0.000530.99947 other
Hyperdip-50-C36other4e-050.99996 other
Hyperdip-50-C37other0.000620.99938 other
Hyperdip-50-C38other0.000140.99986 other
Hyperdip-50-C39 (testset)other0.000830.99917 other
Hyperdip-50-C3other0.008060.99194 other
Hyperdip-50-C40other0.001820.99818 other
Hyperdip-50-C41 (testset)other4e-050.99996 other
Hyperdip-50-C42 (testset)other0.000210.99979 other
Hyperdip-50-C43other0.000850.99915 other
Hyperdip-50-C4other0.000170.99983 other
Hyperdip-50-C5 (testset)other0.001420.99858 other
Hyperdip-50-C6other0.002170.99783 other
Hyperdip-50-C7 (testset)other0.000170.99983 other
Hyperdip-50-C8 (testset)other0.000950.99905 other
Hyperdip-50-C9other0.000210.99979 other
Hyperdip-50-R1other0.008010.99199 other
Hyperdip-50-R2 (testset)other0.000990.99901 other
Hyperdip-50-R3other0.085090.91491 other
Hyperdip-50-R4other0.005040.99496 other
Hyperdip-50-R5 (testset)other0.003830.99617 other
Hyperdip47-50-1other0.002990.99701 other
Hyperdip47-50-2other0.000520.99948 other
Hyperdip47-50-3 (testset)other0.317120.68288 other
Hyperdip47-50-2M1 (testset)other3e-050.99997 other
Hyperdip47-50-C10 (testset)other0.000650.99935 other
Hyperdip47-50-C11other0.008870.99113 other
Hyperdip47-50-C12other0.010670.98933 other
Hyperdip47-50-C13other0.26930.7307 other
Hyperdip47-50-C14-N (testset)other0.199630.80037 other
Hyperdip47-50-C15 (testset)other5e-050.99995 other
Hyperdip47-50-C16other0.003580.99642 other
Hyperdip47-50-C17other0.004380.99562 other
Hyperdip47-50-C18other0.000180.99982 other
Hyperdip47-50-C19other0.396780.60322 other
Hyperdip47-50-C1 (testset)other0.063210.93679 other
Hyperdip47-50-C2 (testset)other0.001930.99807 other
Hyperdip47-50-C3-N (testset)other0.001460.99854 other
Hyperdip47-50-C4other0.000730.99927 other
Hyperdip47-50-C5 (testset)other0.286850.71315 other
Hyperdip47-50-C6 (testset)other0.000180.99982 other
Hyperdip47-50-C7other0.093540.90646 other
Hyperdip47-50-C8other0.001620.99838 other
Hyperdip47-50-C9other0.000230.99977 other
Hypodip-1 (testset)other0.003030.99697 other
Hypodip-2other0.028710.97129 other
Hypodip-2M1 (testset)other0.01680.9832 other
Hypodip-C1other2e-050.99998 other
Hypodip-C2 (testset)other0.06450.9355 other
Hypodip-C3other0.124550.87545 other
Hypodip-C4other0.019810.98019 other
Hypodip-C5other0.000260.99974 other
Hypodip-C6 (testset)other0.000120.99988 other
MLL-1 (testset)other0.000520.99948 other
MLL-2other0.241440.75856 other
MLL-3 (testset)other0.000630.99937 other
MLL-4other0.007110.99289 other
MLL-5 (testset)other0.005360.99464 other
MLL-6 (testset)other0.004610.99539 other
MLL-7other0.009020.99098 other
MLL-8 (testset)other0.039480.96052 other
MLL-2M1other0.071440.92856 other
MLL-2M2 (testset)other0.055880.94412 other
MLL-C1other0.012580.98742 other
MLL-C2other0.147320.85268 other
MLL-C3 (testset)other0.072430.92757 other
MLL-C4other0.050750.94925 other
MLL-C5other0.002690.99731 other
MLL-C6other0.027680.97232 other
MLL-R1 (testset)other0.515190.48481 T-ALL
MLL-R2other0.053360.94664 other
MLL-R3other0.009490.99051 other
MLL-R4other0.01120.9888 other
Normal-1other0.003190.99681 other
Normal-2other7e-040.9993 other
Normal-3other0.001470.99853 other
Normal-C1-Nother0.02740.9726 other
Normal-C10other0.168840.83116 other
Normal-C11-N (testset)other0.009710.99029 other
Normal-C12 (testset)other0.051070.94893 other
Normal-C2-Nother0.069560.93044 other
Normal-C3-Nother0.336140.66386 other
Normal-C4-Nother0.011670.98833 other
Normal-C5other0.000930.99907 other
Normal-C6 (testset)other0.005760.99424 other
Normal-C7-N (testset)other0.046230.95377 other
Normal-C8other0.000270.99973 other
Normal-C9 (testset)other0.001480.99852 other
Normal-R1 (testset)other0.00660.9934 other
Normal-R2-Nother0.001040.99896 other
Normal-R3other0.081180.91882 other
Pseudodip-1other0.001340.99866 other
Pseudodip-2other0.000620.99938 other
Pseudodip-3other0.124870.87513 other
Pseudodip-4 (testset)other0.017170.98283 other
Pseudodip-5 (testset)other0.015030.98497 other
Pseudodip-6 (testset)other0.001190.99881 other
Pseudodip-7other0.000650.99935 other
Pseudodip-8-Nother0.110320.88968 other
Pseudodip-9other0.01070.9893 other
Pseudodip-C10 (testset)other0.000740.99926 other
Pseudodip-C11 (testset)other0.00210.9979 other
Pseudodip-C12 (testset)other0.012420.98758 other
Pseudodip-C13other0.010660.98934 other
Pseudodip-C14 (testset)other0.078140.92186 other
Pseudodip-C15other0.085430.91457 other
Pseudodip-C16-N (testset)other0.119210.88079 other
Pseudodip-C17other0.005290.99471 other
Pseudodip-C18other0.01640.9836 other
Pseudodip-C19other4e-050.99996 other
Pseudodip-C1other0.000290.99971 other
Pseudodip-C2-Nother0.099830.90017 other
Pseudodip-C3other0.013490.98651 other
Pseudodip-C4other0.056470.94353 other
Pseudodip-C5 (testset)other0.003250.99675 other
Pseudodip-C6other0.015020.98498 other
Pseudodip-C7other0.001310.99869 other
Pseudodip-C8other0.071770.92823 other
Pseudodip-C9other0.009320.99068 other
Pseudodip-R1-N (testset)other0.260680.73932 other
T-ALL-10 (testset)T-ALL0.979880.02012 T-ALL
T-ALL-1 (testset)T-ALL0.997660.00234 T-ALL
T-ALL-2 (testset)T-ALL0.923080.07692 T-ALL
T-ALL-3T-ALL0.996360.00364 T-ALL
T-ALL-4 (testset)T-ALL0.999180.00082 T-ALL
T-ALL-5 (testset)T-ALL0.996550.00345 T-ALL
T-ALL-6T-ALL0.999810.00019 T-ALL
T-ALL-7 (testset)T-ALL0.991560.00844 T-ALL
T-ALL-8 (testset)T-ALL0.992390.00761 T-ALL
T-ALL-9T-ALL0.595140.40486 T-ALL
T-ALL-2M1T-ALL0.999380.00062 T-ALL
T-ALL-C10T-ALL0.994640.00536 T-ALL
T-ALL-C11T-ALL0.997760.00224 T-ALL
T-ALL-C12T-ALL0.997440.00256 T-ALL
T-ALL-C13T-ALL0.984210.01579 T-ALL
T-ALL-C14T-ALL0.953160.04684 T-ALL
T-ALL-C15 (testset)T-ALL0.995820.00418 T-ALL
T-ALL-C16 (testset)T-ALL0.979120.02088 T-ALL
T-ALL-C17T-ALL0.982610.01739 T-ALL
T-ALL-C18T-ALL0.93720.0628 T-ALL
T-ALL-C19T-ALL0.995850.00415 T-ALL
T-ALL-C1T-ALL0.979810.02019 T-ALL
T-ALL-C20T-ALL0.982540.01746 T-ALL
T-ALL-C21T-ALL0.997730.00227 T-ALL
T-ALL-C22 (testset)T-ALL0.967470.03253 T-ALL
T-ALL-C23T-ALL0.87110.1289 T-ALL
T-ALL-C24 (testset)T-ALL0.971280.02872 T-ALL
T-ALL-C25 (testset)T-ALL0.999010.00099 T-ALL
T-ALL-C26T-ALL0.977310.02269 T-ALL
T-ALL-C2T-ALL0.981630.01837 T-ALL
T-ALL-C3T-ALL0.996790.00321 T-ALL
T-ALL-C4T-ALL0.939560.06044 T-ALL
T-ALL-C5 (testset)T-ALL0.337390.66261 other
T-ALL-C6T-ALL0.921610.07839 T-ALL
T-ALL-C7 (testset)T-ALL0.8940.106 T-ALL
T-ALL-C8T-ALL0.936320.06368 T-ALL
T-ALL-C9T-ALL0.998570.00143 T-ALL
T-ALL-R1T-ALL0.962590.03741 T-ALL
T-ALL-R2T-ALL0.99840.0016 T-ALL
T-ALL-R3T-ALL0.946650.05335 T-ALL
T-ALL-R4T-ALL0.996450.00355 T-ALL
T-ALL-R5T-ALL0.665310.33469 T-ALL
T-ALL-R6T-ALL0.997870.00213 T-ALL
TEL-AML1-10other0.000250.99975 other
TEL-AML1-11 (testset)other0.005090.99491 other
TEL-AML1-12other0.006520.99348 other
TEL-AML1-13 (testset)other0.003090.99691 other
TEL-AML1-14other0.008170.99183 other
TEL-AML1-1other0.116980.88302 other
TEL-AML1-2other0.008490.99151 other
TEL-AML1-3other7e-040.9993 other
TEL-AML1-4other0.002720.99728 other
TEL-AML1-5 (testset)other0.012770.98723 other
TEL-AML1-6other0.038390.96161 other
TEL-AML1-7other0.001760.99824 other
TEL-AML1-8 (testset)other0.005380.99462 other
TEL-AML1-9other0.006830.99317 other
TEL-AML1-2M1 (testset)other0.001110.99889 other
TEL-AML1-2M2other0.046270.95373 other
TEL-AML1-2M3other0.023720.97628 other
TEL-AML1-2M4 (testset)other0.024730.97527 other
TEL-AML1-2M5other0.060580.93942 other
TEL-AML1-C10other0.005140.99486 other
TEL-AML1-C11other0.012760.98724 other
TEL-AML1-C12other0.00280.9972 other
TEL-AML1-C13other0.001140.99886 other
TEL-AML1-C14 (testset)other0.001180.99882 other
TEL-AML1-C15other0.002560.99744 other
TEL-AML1-C16other0.004010.99599 other
TEL-AML1-C17other0.100960.89904 other
TEL-AML1-C18other0.005940.99406 other
TEL-AML1-C19 (testset)other0.00110.9989 other
TEL-AML1-C1 (testset)other0.005880.99412 other
TEL-AML1-C20 (testset)other0.003440.99656 other
TEL-AML1-C21other0.04320.9568 other
TEL-AML1-C22other0.009710.99029 other
TEL-AML1-C23 (testset)other0.137130.86287 other
TEL-AML1-C24other0.000740.99926 other
TEL-AML1-C25other0.006360.99364 other
TEL-AML1-C26 (testset)other0.002710.99729 other
TEL-AML1-C27other0.019920.98008 other
TEL-AML1-C28 (testset)other0.001210.99879 other
TEL-AML1-C29other0.01970.9803 other
TEL-AML1-C2other0.002070.99793 other
TEL-AML1-C30other0.003810.99619 other
TEL-AML1-C31 (testset)other0.000280.99972 other
TEL-AML1-C32other0.000220.99978 other
TEL-AML1-C33 (testset)other0.014460.98554 other
TEL-AML1-C34other0.003080.99692 other
TEL-AML1-C35other0.015380.98462 other
TEL-AML1-C36 (testset)other0.014370.98563 other
TEL-AML1-C37other0.000330.99967 other
TEL-AML1-C38other0.007360.99264 other
TEL-AML1-C39other0.021920.97808 other
TEL-AML1-C3other0.006020.99398 other
TEL-AML1-C40other0.004850.99515 other
TEL-AML1-C41other0.020490.97951 other
TEL-AML1-C42other0.297760.70224 other
TEL-AML1-C43other0.060870.93913 other
TEL-AML1-C44other0.003330.99667 other
TEL-AML1-C45other0.029720.97028 other
TEL-AML1-C46other0.000560.99944 other
TEL-AML1-C47other0.000330.99967 other
TEL-AML1-C48other0.000450.99955 other
TEL-AML1-C49 (testset)other0.004330.99567 other
TEL-AML1-C4 (testset)other0.004570.99543 other
TEL-AML1-C50other0.00290.9971 other
TEL-AML1-C51 (testset)other0.009630.99037 other
TEL-AML1-C52other0.000970.99903 other
TEL-AML1-C53 (testset)other0.156020.84398 other
TEL-AML1-C54other0.000420.99958 other
TEL-AML1-C55 (testset)other0.013710.98629 other
TEL-AML1-C56other0.006440.99356 other
TEL-AML1-C57other0.005190.99481 other
TEL-AML1-C5 (testset)other0.002850.99715 other
TEL-AML1-C6other0.005230.99477 other
TEL-AML1-C7other0.003110.99689 other
TEL-AML1-C8other0.129160.87084 other
TEL-AML1-C9other0.026150.97385 other
TEL-AML1-R1 (testset)other0.059960.94004 other
TEL-AML1-R2 (testset)other0.019840.98016 other
TEL-AML1-R3other0.002610.99739 other

 


Generated by StAM on Tue Sep 7 18:30:20 2004