GO:0008152


GO:0008152

metabolism
(annotated genes)

Biological
Process

Parent node

This leaf node contains 214 genes

The following 59 of these are used in classification:

 SymbolGenenameMLL scoreother score
40913_atATP2B4 ATPase, Ca++ transporting, plasma membrane 4-0.89350.0569
40456_atSLC39A8 solute carrier family 39 (zinc transporter), member 80.5036-0.0321
40082_atACSL1 acyl-CoA synthetase long-chain family member 10.488-0.0311
38201_atBCAT1 branched chain aminotransferase 1, cytosolic0.4695-0.0299
33267_atATP8A1 ATPase, aminophospholipid transporter (APLT), Class I, type 8A, member 10.3358-0.0214
40866_atNIPSNAP1 nipsnap homolog 1 (C. elegans)-0.32750.0209
33408_atKIAA0934 KIAA0934 protein-0.28340.0181
33263_atHSRTSBETA rTS beta protein-0.28060.0179
37211_atBDH 3-hydroxybutyrate dehydrogenase (heart, mitochondrial)0.2458-0.0157
41440_atHSD17B8 hydroxysteroid (17-beta) dehydrogenase 8-0.24330.0155
32332_atIDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial-0.22020.014
36159_s_atPRNP prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)0.2105-0.0134
824_atGSTO1 glutathione S-transferase omega 1-0.19690.0125
37930_atATP7B ATPase, Cu++ transporting, beta polypeptide (Wilson disease)-0.19350.0123
37795_atARSB arylsulfatase B-0.1750.0112
39041_atDLAT dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.168-0.0107
177_atPLD1 phospholipase D1, phophatidylcholine-specific0.1649-0.0105
33881_atACSL3 acyl-CoA synthetase long-chain family member 3-0.15160.0097
32836_atAGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)-0.14260.0091
39814_s_atDHRS7 dehydrogenase/reductase (SDR family) member 70.1288-0.0082
1348_s_atPCCA propionyl Coenzyme A carboxylase, alpha polypeptide-0.12530.008
33062_atGSTA1 glutathione S-transferase A1-0.11560.0074
36736_f_atPSPH phosphoserine phosphatase0.1127-0.0072
40782_atDHRS3 dehydrogenase/reductase (SDR family) member 30.0987-0.0063
33738_r_atMTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)-0.09310.0059
37963_atARSA arylsulfatase A0.0888-0.0057
38315_atALDH1A2 aldehyde dehydrogenase 1 family, member A2-0.08780.0056
41554_atDECR1 2,4-dienoyl CoA reductase 1, mitochondrial0.0843-0.0054
36626_atHSD17B4 hydroxysteroid (17-beta) dehydrogenase 4-0.08380.0053
32798_atGSTM3 glutathione S-transferase M3 (brain)-0.07350.0047
39064_atMTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)-0.07250.0046
37278_atTAZ tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome)-0.07030.0045
33407_atKIAA0934 KIAA0934 protein-0.06880.0044
38034_atSTS steroid sulfatase (microsomal), arylsulfatase C, isozyme S0.0659-0.0042
37880_atAGXT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase)-0.06540.0042
32108_atSPR sepiapterin reductase (7,8-dihydrobiopterin-0.06450.0041
34631_atEYA4 eyes absent homolog 4 (Drosophila)-0.0640.0041
37332_r_atALDH4A1 aldehyde dehydrogenase 4 family, member A1-0.05780.0037
32482_atATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide-0.05260.0034
32676_atALDH6A1 aldehyde dehydrogenase 6 family, member A1-0.05110.0033
35648_atAUTS2 autism susceptibility candidate 2-0.05050.0032
31530_atACACB acetyl-Coenzyme A carboxylase beta-0.04770.003
37704_atBCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide (maple syrup urine disease)0.0429-0.0027
41089_atATP2B4 ATPase, Ca++ transporting, plasma membrane 4-0.0390.0025
34973_atATP8A1 ATPase, aminophospholipid transporter (APLT), Class I, type 8A, member 10.0378-0.0024
40470_atOGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)0.0343-0.0022
31464_atDCT dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)-0.02770.0018
37661_atATP2B1 ATPase, Ca++ transporting, plasma membrane 10.0268-0.0017
41221_atPGAM1 phosphoglycerate mutase 1 (brain)-0.02670.0017
38178_atHSD17B2 hydroxysteroid (17-beta) dehydrogenase 20.0252-0.0016
36120_atFVT1 follicular lymphoma variant translocation 1-0.02260.0014
40815_g_atIDS iduronate 2-sulfatase (Hunter syndrome)-0.02050.0013
32537_atBG1 lipidosin0.0204-0.0013
40433_atGNS glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID)0.018-0.0011
33264_atHSRTSBETA rTS beta protein-0.0150.001
37111_g_atPFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3-0.01479e-04
40914_s_atATP2B4 ATPase, Ca++ transporting, plasma membrane 4-0.00946e-04
36482_s_atATP2A3 ATPase, Ca++ transporting, ubiquitous-0.00594e-04
33370_r_atSC4MOL sterol-C4-methyl oxidase-like0.0021-1e-04

Performance on training data

 SensitivitySpecificity
MLL0.461541
other10.46154

Performance on test data

 SensitivitySpecificity
MLL0.428571
other10.42857

Predictions

 ClassMLLotherPredictionn
BCR-ABL-1 (testset)other0.00960.9904 other
BCR-ABL-2 (testset)other0.013280.98672 other
BCR-ABL-3other0.065380.93462 other
BCR-ABL-4other0.010640.98936 other
BCR-ABL-5 (testset)other0.015790.98421 other
BCR-ABL-6other0.015460.98454 other
BCR-ABL-7 (testset)other0.005910.99409 other
BCR-ABL-8 (testset)other0.007960.99204 other
BCR-ABL-9other0.037660.96234 other
BCR-ABL-C1 (testset)other0.051290.94871 other
BCR-ABL-Hyperdip-10other0.005050.99495 other
BCR-ABL-Hyperdip-R5other0.012030.98797 other
BCR-ABL-R1 (testset)other0.006370.99363 other
BCR-ABL-R2 (testset)other0.008970.99103 other
BCR-ABL-R3 (testset)other0.012580.98742 other
E2A-PBX1-10other0.011390.98861 other
E2A-PBX1-11other0.048140.95186 other
E2A-PBX1-12 (testset)other0.091830.90817 other
E2A-PBX1-13 (testset)other0.021630.97837 other
E2A-PBX1-1other0.049470.95053 other
E2A-PBX1-2other0.013430.98657 other
E2A-PBX1-3other0.008570.99143 other
E2A-PBX1-4other0.011590.98841 other
E2A-PBX1-5other0.04550.9545 other
E2A-PBX1-6 (testset)other0.086830.91317 other
E2A-PBX1-7 (testset)other0.048290.95171 other
E2A-PBX1-8 (testset)other0.013550.98645 other
E2A-PBX1-9other0.024560.97544 other
E2A-PBX1-2M1other0.02480.9752 other
E2A-PBX1-C10 (testset)other0.006950.99305 other
E2A-PBX1-C11other0.06990.9301 other
E2A-PBX1-C12other0.011920.98808 other
E2A-PBX1-C1other0.036410.96359 other
E2A-PBX1-C2 (testset)other0.006520.99348 other
E2A-PBX1-C3other0.062290.93771 other
E2A-PBX1-C4other0.037090.96291 other
E2A-PBX1-C5other0.029120.97088 other
E2A-PBX1-C6other0.022570.97743 other
E2A-PBX1-C7other0.024070.97593 other
E2A-PBX1-C8 (testset)other0.020450.97955 other
E2A-PBX1-C9other0.024220.97578 other
E2A-PBX1-R1 (testset)other0.043840.95616 other
Hyperdip-50-10other0.005650.99435 other
Hyperdip-50-11other0.038960.96104 other
Hyperdip-50-12other0.023870.97613 other
Hyperdip-50-13other0.043560.95644 other
Hyperdip-50-14other0.004460.99554 other
Hyperdip-50-1other0.009790.99021 other
Hyperdip-50-2other0.003330.99667 other
Hyperdip-50-3other0.022530.97747 other
Hyperdip-50-4other0.081470.91853 other
Hyperdip-50-5other0.026520.97348 other
Hyperdip-50-6other0.017360.98264 other
Hyperdip-50-7 (testset)other0.062770.93723 other
Hyperdip-50-8other0.009680.99032 other
Hyperdip-50-9 (testset)other0.020590.97941 other
Hyperdip-50-2M1other0.004450.99555 other
Hyperdip-50-2M2 (testset)other0.050170.94983 other
Hyperdip-50-C10 (testset)other0.030590.96941 other
Hyperdip-50-C11other0.014290.98571 other
Hyperdip-50-C12other0.021530.97847 other
Hyperdip-50-C13other0.007640.99236 other
Hyperdip-50-C14other0.044270.95573 other
Hyperdip-50-C15other0.013120.98688 other
Hyperdip-50-C16other0.084320.91568 other
Hyperdip-50-C17other0.046440.95356 other
Hyperdip-50-C18 (testset)other0.011570.98843 other
Hyperdip-50-C19other0.001440.99856 other
Hyperdip-50-C1 (testset)other0.025260.97474 other
Hyperdip-50-C20other0.00380.9962 other
Hyperdip-50-C21other0.000770.99923 other
Hyperdip-50-C22other0.009810.99019 other
Hyperdip-50-C23 (testset)other0.011240.98876 other
Hyperdip-50-C24other0.050220.94978 other
Hyperdip-50-C25 (testset)other0.022640.97736 other
Hyperdip-50-C26 (testset)other0.051440.94856 other
Hyperdip-50-C27-Nother0.096010.90399 other
Hyperdip-50-C28other0.120410.87959 other
Hyperdip-50-C29other0.018650.98135 other
Hyperdip-50-C2other0.031080.96892 other
Hyperdip-50-C30 (testset)other0.026610.97339 other
Hyperdip-50-C31 (testset)other0.00410.9959 other
Hyperdip-50-C32other0.029050.97095 other
Hyperdip-50-C33other0.02440.9756 other
Hyperdip-50-C34other0.02980.9702 other
Hyperdip-50-C35other0.004190.99581 other
Hyperdip-50-C36 (testset)other0.005430.99457 other
Hyperdip-50-C37other0.029120.97088 other
Hyperdip-50-C38other0.009720.99028 other
Hyperdip-50-C39other0.013250.98675 other
Hyperdip-50-C3 (testset)other0.01460.9854 other
Hyperdip-50-C40 (testset)other0.00420.9958 other
Hyperdip-50-C41other0.01270.9873 other
Hyperdip-50-C42 (testset)other0.001360.99864 other
Hyperdip-50-C43 (testset)other0.033670.96633 other
Hyperdip-50-C4other0.033280.96672 other
Hyperdip-50-C5other0.025140.97486 other
Hyperdip-50-C6 (testset)other0.017540.98246 other
Hyperdip-50-C7other0.006770.99323 other
Hyperdip-50-C8other0.03040.9696 other
Hyperdip-50-C9other0.030510.96949 other
Hyperdip-50-R1 (testset)other0.012270.98773 other
Hyperdip-50-R2other0.023520.97648 other
Hyperdip-50-R3 (testset)other0.062490.93751 other
Hyperdip-50-R4other0.017580.98242 other
Hyperdip-50-R5 (testset)other0.01540.9846 other
Hyperdip47-50-1other0.036810.96319 other
Hyperdip47-50-2other0.002260.99774 other
Hyperdip47-50-3other0.190230.80977 other
Hyperdip47-50-2M1other0.048380.95162 other
Hyperdip47-50-C10 (testset)other0.015130.98487 other
Hyperdip47-50-C11other0.018340.98166 other
Hyperdip47-50-C12other0.023550.97645 other
Hyperdip47-50-C13other0.094780.90522 other
Hyperdip47-50-C14-Nother0.009110.99089 other
Hyperdip47-50-C15other0.042140.95786 other
Hyperdip47-50-C16 (testset)other0.258640.74136 other
Hyperdip47-50-C17other0.002730.99727 other
Hyperdip47-50-C18other0.296540.70346 other
Hyperdip47-50-C19other0.028690.97131 other
Hyperdip47-50-C1 (testset)other0.285050.71495 other
Hyperdip47-50-C2other0.041380.95862 other
Hyperdip47-50-C3-Nother0.143350.85665 other
Hyperdip47-50-C4other0.037670.96233 other
Hyperdip47-50-C5other0.061910.93809 other
Hyperdip47-50-C6other0.001370.99863 other
Hyperdip47-50-C7other0.010310.98969 other
Hyperdip47-50-C8other0.004210.99579 other
Hyperdip47-50-C9other0.104920.89508 other
Hypodip-1other0.014890.98511 other
Hypodip-2other0.026630.97337 other
Hypodip-2M1 (testset)other0.02970.9703 other
Hypodip-C1 (testset)other0.005310.99469 other
Hypodip-C2other0.101240.89876 other
Hypodip-C3other0.022310.97769 other
Hypodip-C4other0.032050.96795 other
Hypodip-C5 (testset)other0.00540.9946 other
Hypodip-C6 (testset)other0.047570.95243 other
MLL-1MLL0.48810.5119 other
MLL-2 (testset)MLL0.361350.63865 other
MLL-3 (testset)MLL0.634380.36562 MLL
MLL-4MLL0.944510.05549 MLL
MLL-5 (testset)MLL0.2830.717 other
MLL-6 (testset)MLL0.77750.2225 MLL
MLL-7MLL0.34550.6545 other
MLL-8MLL0.440680.55932 other
MLL-2M1 (testset)MLL0.043820.95618 other
MLL-2M2MLL0.833590.16641 MLL
MLL-C1MLL0.790270.20973 MLL
MLL-C2 (testset)MLL0.599340.40066 MLL
MLL-C3MLL0.206230.79377 other
MLL-C4MLL0.137910.86209 other
MLL-C5MLL0.698190.30181 MLL
MLL-C6MLL0.501770.49823 MLL
MLL-R1MLL0.480630.51937 other
MLL-R2MLL0.426220.57378 other
MLL-R3MLL0.653540.34646 MLL
MLL-R4 (testset)MLL0.142260.85774 other
Normal-1other0.048910.95109 other
Normal-2other0.045250.95475 other
Normal-3other0.025150.97485 other
Normal-C1-N (testset)other0.019310.98069 other
Normal-C10 (testset)other0.037260.96274 other
Normal-C11-Nother0.175840.82416 other
Normal-C12other0.012820.98718 other
Normal-C2-Nother0.011180.98882 other
Normal-C3-Nother0.033210.96679 other
Normal-C4-Nother0.022230.97777 other
Normal-C5 (testset)other0.126990.87301 other
Normal-C6 (testset)other0.04810.9519 other
Normal-C7-Nother0.043160.95684 other
Normal-C8other0.011370.98863 other
Normal-C9other0.013210.98679 other
Normal-R1 (testset)other0.085890.91411 other
Normal-R2-Nother0.167670.83233 other
Normal-R3other0.169720.83028 other
Pseudodip-1other0.008410.99159 other
Pseudodip-2 (testset)other0.009050.99095 other
Pseudodip-3other0.027110.97289 other
Pseudodip-4other0.011890.98811 other
Pseudodip-5other0.0150.985 other
Pseudodip-6other0.031870.96813 other
Pseudodip-7other0.008590.99141 other
Pseudodip-8-Nother0.050.95 other
Pseudodip-9 (testset)other0.020480.97952 other
Pseudodip-C10other0.000920.99908 other
Pseudodip-C11other0.009370.99063 other
Pseudodip-C12other0.007440.99256 other
Pseudodip-C13other0.030070.96993 other
Pseudodip-C14other0.00740.9926 other
Pseudodip-C15other0.083630.91637 other
Pseudodip-C16-N (testset)other0.008860.99114 other
Pseudodip-C17other0.01890.9811 other
Pseudodip-C18other0.021390.97861 other
Pseudodip-C19other0.027740.97226 other
Pseudodip-C1other0.080060.91994 other
Pseudodip-C2-Nother0.037390.96261 other
Pseudodip-C3other0.026840.97316 other
Pseudodip-C4 (testset)other0.070360.92964 other
Pseudodip-C5other0.03810.9619 other
Pseudodip-C6other0.020680.97932 other
Pseudodip-C7other0.009460.99054 other
Pseudodip-C8other0.034210.96579 other
Pseudodip-C9other0.009190.99081 other
Pseudodip-R1-N (testset)other0.009020.99098 other
T-ALL-10other0.002960.99704 other
T-ALL-1other0.022950.97705 other
T-ALL-2other0.03710.9629 other
T-ALL-3 (testset)other0.001740.99826 other
T-ALL-4 (testset)other0.001940.99806 other
T-ALL-5 (testset)other0.006420.99358 other
T-ALL-6 (testset)other0.012360.98764 other
T-ALL-7other0.008610.99139 other
T-ALL-8other0.004910.99509 other
T-ALL-9other0.023620.97638 other
T-ALL-2M1 (testset)other0.010040.98996 other
T-ALL-C10other0.004560.99544 other
T-ALL-C11other0.005240.99476 other
T-ALL-C12other0.00710.9929 other
T-ALL-C13other0.007410.99259 other
T-ALL-C14 (testset)other0.020350.97965 other
T-ALL-C15other0.008540.99146 other
T-ALL-C16 (testset)other0.064520.93548 other
T-ALL-C17 (testset)other0.009530.99047 other
T-ALL-C18other0.017080.98292 other
T-ALL-C19other0.006980.99302 other
T-ALL-C1 (testset)other0.017350.98265 other
T-ALL-C20other0.011280.98872 other
T-ALL-C21 (testset)other0.001610.99839 other
T-ALL-C22other0.003350.99665 other
T-ALL-C23other0.034440.96556 other
T-ALL-C24 (testset)other0.006150.99385 other
T-ALL-C25other0.003520.99648 other
T-ALL-C26other0.009660.99034 other
T-ALL-C2other0.003750.99625 other
T-ALL-C3 (testset)other0.002410.99759 other
T-ALL-C4other0.015630.98437 other
T-ALL-C5other0.063250.93675 other
T-ALL-C6other0.006980.99302 other
T-ALL-C7other0.016910.98309 other
T-ALL-C8other0.035590.96441 other
T-ALL-C9other0.006080.99392 other
T-ALL-R1 (testset)other0.002030.99797 other
T-ALL-R2other0.005360.99464 other
T-ALL-R3other0.00290.9971 other
T-ALL-R4other0.00520.9948 other
T-ALL-R5 (testset)other0.009280.99072 other
T-ALL-R6 (testset)other0.01630.9837 other
TEL-AML1-10other0.001220.99878 other
TEL-AML1-11 (testset)other0.01530.9847 other
TEL-AML1-12other0.005540.99446 other
TEL-AML1-13other0.002760.99724 other
TEL-AML1-14other0.000830.99917 other
TEL-AML1-1other0.0150.985 other
TEL-AML1-2 (testset)other0.005980.99402 other
TEL-AML1-3other0.002230.99777 other
TEL-AML1-4 (testset)other0.001860.99814 other
TEL-AML1-5 (testset)other0.008970.99103 other
TEL-AML1-6 (testset)other0.062380.93762 other
TEL-AML1-7other0.008090.99191 other
TEL-AML1-8 (testset)other0.005210.99479 other
TEL-AML1-9 (testset)other0.011960.98804 other
TEL-AML1-2M1other0.000980.99902 other
TEL-AML1-2M2 (testset)other0.003780.99622 other
TEL-AML1-2M3other0.007720.99228 other
TEL-AML1-2M4other0.008310.99169 other
TEL-AML1-2M5other0.002670.99733 other
TEL-AML1-C10 (testset)other0.005910.99409 other
TEL-AML1-C11 (testset)other0.00760.9924 other
TEL-AML1-C12 (testset)other0.006610.99339 other
TEL-AML1-C13 (testset)other0.002930.99707 other
TEL-AML1-C14other0.005980.99402 other
TEL-AML1-C15other0.001040.99896 other
TEL-AML1-C16other0.012320.98768 other
TEL-AML1-C17other0.018660.98134 other
TEL-AML1-C18other0.002390.99761 other
TEL-AML1-C19other0.00180.9982 other
TEL-AML1-C1other0.026280.97372 other
TEL-AML1-C20other0.004990.99501 other
TEL-AML1-C21 (testset)other0.028980.97102 other
TEL-AML1-C22 (testset)other0.007980.99202 other
TEL-AML1-C23other0.039260.96074 other
TEL-AML1-C24other0.001240.99876 other
TEL-AML1-C25other0.006350.99365 other
TEL-AML1-C26 (testset)other0.002610.99739 other
TEL-AML1-C27other0.005260.99474 other
TEL-AML1-C28 (testset)other0.001870.99813 other
TEL-AML1-C29other0.000450.99955 other
TEL-AML1-C2other0.00770.9923 other
TEL-AML1-C30 (testset)other0.00140.9986 other
TEL-AML1-C31 (testset)other0.000860.99914 other
TEL-AML1-C32other0.000480.99952 other
TEL-AML1-C33other0.002370.99763 other
TEL-AML1-C34 (testset)other0.000510.99949 other
TEL-AML1-C35 (testset)other0.01130.9887 other
TEL-AML1-C36other0.005640.99436 other
TEL-AML1-C37 (testset)other0.001740.99826 other
TEL-AML1-C38other0.001830.99817 other
TEL-AML1-C39other0.013570.98643 other
TEL-AML1-C3other0.006020.99398 other
TEL-AML1-C40 (testset)other0.013440.98656 other
TEL-AML1-C41other0.011250.98875 other
TEL-AML1-C42 (testset)other0.005810.99419 other
TEL-AML1-C43other0.007910.99209 other
TEL-AML1-C44other0.005920.99408 other
TEL-AML1-C45other0.01910.9809 other
TEL-AML1-C46 (testset)other0.007620.99238 other
TEL-AML1-C47other0.009920.99008 other
TEL-AML1-C48other0.003660.99634 other
TEL-AML1-C49 (testset)other0.007470.99253 other
TEL-AML1-C4 (testset)other0.005850.99415 other
TEL-AML1-C50 (testset)other0.013890.98611 other
TEL-AML1-C51other0.003650.99635 other
TEL-AML1-C52other0.001230.99877 other
TEL-AML1-C53 (testset)other0.011770.98823 other
TEL-AML1-C54 (testset)other0.003980.99602 other
TEL-AML1-C55other0.010.99 other
TEL-AML1-C56 (testset)other0.016870.98313 other
TEL-AML1-C57other0.002770.99723 other
TEL-AML1-C5other0.008630.99137 other
TEL-AML1-C6 (testset)other0.005720.99428 other
TEL-AML1-C7 (testset)other0.006960.99304 other
TEL-AML1-C8other0.098580.90142 other
TEL-AML1-C9other0.045230.95477 other
TEL-AML1-R1 (testset)other0.005890.99411 other
TEL-AML1-R2other0.008320.99168 other
TEL-AML1-R3other0.008750.99125 other

 


Generated by StAM on Wed Sep 8 11:56:31 2004