GO:0007268


GO:0007268

synaptic transmission
(annotated genes)

Biological
Process

Parent node

This leaf node contains 189 genes

The following 64 of these are used in classification:

 SymbolGenenameMLL scoreother score
37978_atQPRT quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating))1.1585-0.0738
35663_atNPTX2 neuronal pentraxin II0.8477-0.054
38075_atSYPL synaptophysin-like protein0.5305-0.0338
32623_atGABBR1 gamma-aminobutyric acid (GABA) B receptor, 1-0.47430.0302
38604_atNPY neuropeptide Y-0.39450.0251
41346_atLARGE like-glycosyltransferase-0.37850.0241
32138_atDNM1 dynamin 10.2167-0.0138
38107_atUNC119 unc-119 homolog (C. elegans)0.2123-0.0135
40075_atSYT1 synaptotagmin I0.1958-0.0125
34904_atGRIK5 glutamate receptor, ionotropic, kainate 5-0.18050.0115
34554_atGLRA2 glycine receptor, alpha 2-0.17590.0112
38203_atKCNN1 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1-0.16890.0108
1112_g_atNCAM1 neural cell adhesion molecule 10.1672-0.0107
31468_f_atGRM1 glutamate receptor, metabotropic 1-0.15750.01
31391_atHAP1 huntingtin-associated protein 1 (neuroan 1)-0.15270.0097
35880_atKIF5A kinesin family member 5A-0.14060.009
36762_atGABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2-0.13880.0088
31554_atCHRND cholinergic receptor, nicotinic, delta polypeptide-0.12970.0083
41052_s_atCACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit-0.12720.0081
34906_g_atGRIK5 glutamate receptor, ionotropic, kainate 5-0.12510.008
37867_atMOG myelin oligodendrocyte glycoprotein-0.11350.0072
37298_atGABARAP GABA(A) receptor-associated protein-0.09970.0064
33624_atCACNA1E calcium channel, voltage-dependent, alpha 1E subunit-0.09620.0061
32492_g_atDRD3 dopamine receptor D30.0905-0.0058
33626_atCACNA1E calcium channel, voltage-dependent, alpha 1E subunit-0.08650.0055
39321_atGABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5-0.08630.0055
741_g_atHTR3A 5-hydroxytryptamine (serotonin) receptor 3A0.0848-0.0054
38243_atNCAM1 neural cell adhesion molecule 1-0.07190.0046
32489_atGRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B-0.07110.0045
39599_atSLC6A1 solute carrier family 6 (neurotransmitter transporter, GABA), member 1-0.06960.0044
36254_atTAC1 tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)-0.06850.0044
34701_atDLG4 discs, large homolog 4 (Drosophila)-0.050.0032
36740_atDOC2A double C2-like domains, alpha-0.04650.003
33202_f_atFRDA Friedreich ataxia0.0451-0.0029
35817_atMBP myelin basic protein0.0438-0.0028
41325_atKCNK3 potassium channel, subfamily K, member 3-0.04330.0028
31551_atGABRR2 gamma-aminobutyric acid (GABA) receptor, rho 2-0.04320.0028
38110_atSDCBP syndecan binding protein (syntenin)-0.04120.0026
35080_atNTSR1 neurotensin receptor 1 (high affinity)-0.03880.0025
35471_g_atHTR2A 5-hydroxytryptamine (serotonin) receptor 2A0.0384-0.0024
40388_atDLGAP1 discs, large (Drosophila) homolog-associated protein 1-0.03590.0023
36759_atCHRM3 cholinergic receptor, muscarinic 30.0283-0.0018
34550_atDRD1 dopamine receptor D1-0.02820.0018
32425_atCHRNA2 cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)-0.02820.0018
39566_atCHRNA7 cholinergic receptor, nicotinic, alpha polypeptide 7-0.02460.0016
31726_atGABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3-0.02440.0016
38268_atSLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 10.0241-0.0015
35503_atHTR1B 5-hydroxytryptamine (serotonin) receptor 1B-0.02340.0015
35028_atGABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 10.0228-0.0015
36306_atKCNQ3 potassium voltage-gated channel, KQT-like subfamily, member 3-0.0180.0011
37782_atSST somatostatin0.0152-0.001
34918_atSCN2B sodium channel, voltage-gated, type II, beta-0.01499e-04
31310_atGLRA1 glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)-0.01248e-04
32494_atHTR1D 5-hydroxytryptamine (serotonin) receptor 1D-0.00976e-04
36855_r_atGRIA1 glutamate receptor, ionotropic, AMPA 1-0.00946e-04
31450_s_atRIT2 Ras-like without CAAX 2-0.0085e-04
35048_atGRIA3 glutamate receptor, ionotrophic, AMPA 3-0.00634e-04
39573_atGRIK2 glutamate receptor, ionotropic, kainate 20.0041-3e-04
37135_f_atGRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1-0.00413e-04
39877_atKCNC4 potassium voltage-gated channel, Shaw-related subfamily, member 4-0.00312e-04
36698_atAPBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)-0.00161e-04
33550_atHTR2C 5-hydroxytryptamine (serotonin) receptor 2C0.0015-1e-04
37051_atKCNN3 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3-0.00121e-04
33510_s_atGRM1 glutamate receptor, metabotropic 1-0.0011e-04

Performance on training data

 SensitivitySpecificity
MLL0.461541
other10.46154

Performance on test data

 SensitivitySpecificity
MLL0.285711
other10.28571

Predictions

 ClassMLLotherPredictionn
BCR-ABL-1 (testset)other0.0250.975 other
BCR-ABL-2 (testset)other0.011560.98844 other
BCR-ABL-3other0.003840.99616 other
BCR-ABL-4other0.021550.97845 other
BCR-ABL-5 (testset)other0.005210.99479 other
BCR-ABL-6other0.008580.99142 other
BCR-ABL-7 (testset)other0.018370.98163 other
BCR-ABL-8 (testset)other0.014590.98541 other
BCR-ABL-9other0.013930.98607 other
BCR-ABL-C1 (testset)other0.013160.98684 other
BCR-ABL-Hyperdip-10other0.000850.99915 other
BCR-ABL-Hyperdip-R5other0.002080.99792 other
BCR-ABL-R1 (testset)other0.03480.9652 other
BCR-ABL-R2 (testset)other0.006390.99361 other
BCR-ABL-R3 (testset)other0.015010.98499 other
E2A-PBX1-10other0.017910.98209 other
E2A-PBX1-11other0.008040.99196 other
E2A-PBX1-12 (testset)other0.017320.98268 other
E2A-PBX1-13 (testset)other0.093530.90647 other
E2A-PBX1-1other0.0390.961 other
E2A-PBX1-2other0.006480.99352 other
E2A-PBX1-3other0.031050.96895 other
E2A-PBX1-4other0.030490.96951 other
E2A-PBX1-5other0.054880.94512 other
E2A-PBX1-6 (testset)other0.029490.97051 other
E2A-PBX1-7 (testset)other0.012850.98715 other
E2A-PBX1-8 (testset)other0.019220.98078 other
E2A-PBX1-9other0.066010.93399 other
E2A-PBX1-2M1other0.015440.98456 other
E2A-PBX1-C10 (testset)other0.016210.98379 other
E2A-PBX1-C11other0.018660.98134 other
E2A-PBX1-C12other0.03160.9684 other
E2A-PBX1-C1other0.005930.99407 other
E2A-PBX1-C2 (testset)other0.023190.97681 other
E2A-PBX1-C3other0.073670.92633 other
E2A-PBX1-C4other0.01180.9882 other
E2A-PBX1-C5other0.021880.97812 other
E2A-PBX1-C6other0.007340.99266 other
E2A-PBX1-C7other0.033490.96651 other
E2A-PBX1-C8 (testset)other0.007560.99244 other
E2A-PBX1-C9other0.026890.97311 other
E2A-PBX1-R1 (testset)other0.014910.98509 other
Hyperdip-50-10other0.002060.99794 other
Hyperdip-50-11other0.007350.99265 other
Hyperdip-50-12other0.007930.99207 other
Hyperdip-50-13other0.005070.99493 other
Hyperdip-50-14other0.001310.99869 other
Hyperdip-50-1other0.008550.99145 other
Hyperdip-50-2other0.003030.99697 other
Hyperdip-50-3other0.003830.99617 other
Hyperdip-50-4other0.017070.98293 other
Hyperdip-50-5other0.019430.98057 other
Hyperdip-50-6other0.001840.99816 other
Hyperdip-50-7 (testset)other0.011070.98893 other
Hyperdip-50-8other0.00440.9956 other
Hyperdip-50-9 (testset)other0.001850.99815 other
Hyperdip-50-2M1other0.003070.99693 other
Hyperdip-50-2M2 (testset)other0.002270.99773 other
Hyperdip-50-C10 (testset)other0.006310.99369 other
Hyperdip-50-C11other0.007570.99243 other
Hyperdip-50-C12other0.004440.99556 other
Hyperdip-50-C13other0.001720.99828 other
Hyperdip-50-C14other0.00750.9925 other
Hyperdip-50-C15other0.006090.99391 other
Hyperdip-50-C16other0.001390.99861 other
Hyperdip-50-C17other0.006930.99307 other
Hyperdip-50-C18 (testset)other0.001680.99832 other
Hyperdip-50-C19other0.00570.9943 other
Hyperdip-50-C1 (testset)other0.010070.98993 other
Hyperdip-50-C20other0.005780.99422 other
Hyperdip-50-C21other0.002970.99703 other
Hyperdip-50-C22other0.0010.999 other
Hyperdip-50-C23 (testset)other0.001110.99889 other
Hyperdip-50-C24other0.004340.99566 other
Hyperdip-50-C25 (testset)other0.001590.99841 other
Hyperdip-50-C26 (testset)other0.002860.99714 other
Hyperdip-50-C27-Nother0.005230.99477 other
Hyperdip-50-C28other0.008860.99114 other
Hyperdip-50-C29other0.00790.9921 other
Hyperdip-50-C2other0.009380.99062 other
Hyperdip-50-C30 (testset)other0.001510.99849 other
Hyperdip-50-C31 (testset)other0.002260.99774 other
Hyperdip-50-C32other0.005420.99458 other
Hyperdip-50-C33other0.003060.99694 other
Hyperdip-50-C34other0.001870.99813 other
Hyperdip-50-C35other0.001970.99803 other
Hyperdip-50-C36 (testset)other0.001710.99829 other
Hyperdip-50-C37other0.003830.99617 other
Hyperdip-50-C38other0.000870.99913 other
Hyperdip-50-C39other0.001590.99841 other
Hyperdip-50-C3 (testset)other0.003170.99683 other
Hyperdip-50-C40 (testset)other0.001110.99889 other
Hyperdip-50-C41other0.001170.99883 other
Hyperdip-50-C42 (testset)other0.000340.99966 other
Hyperdip-50-C43 (testset)other0.003850.99615 other
Hyperdip-50-C4other0.002720.99728 other
Hyperdip-50-C5other0.00770.9923 other
Hyperdip-50-C6 (testset)other0.004280.99572 other
Hyperdip-50-C7other0.004250.99575 other
Hyperdip-50-C8other0.034230.96577 other
Hyperdip-50-C9other0.009440.99056 other
Hyperdip-50-R1 (testset)other0.002350.99765 other
Hyperdip-50-R2other0.00380.9962 other
Hyperdip-50-R3 (testset)other0.001020.99898 other
Hyperdip-50-R4other0.001570.99843 other
Hyperdip-50-R5 (testset)other0.005160.99484 other
Hyperdip47-50-1other0.021620.97838 other
Hyperdip47-50-2other0.003320.99668 other
Hyperdip47-50-3other0.058270.94173 other
Hyperdip47-50-2M1other0.004230.99577 other
Hyperdip47-50-C10 (testset)other0.012540.98746 other
Hyperdip47-50-C11other0.00990.9901 other
Hyperdip47-50-C12other0.034740.96526 other
Hyperdip47-50-C13other0.006960.99304 other
Hyperdip47-50-C14-Nother0.001470.99853 other
Hyperdip47-50-C15other0.006780.99322 other
Hyperdip47-50-C16 (testset)other0.010610.98939 other
Hyperdip47-50-C17other0.003540.99646 other
Hyperdip47-50-C18other0.011960.98804 other
Hyperdip47-50-C19other0.003730.99627 other
Hyperdip47-50-C1 (testset)other0.064780.93522 other
Hyperdip47-50-C2other0.001840.99816 other
Hyperdip47-50-C3-Nother0.034320.96568 other
Hyperdip47-50-C4other0.00840.9916 other
Hyperdip47-50-C5other0.048280.95172 other
Hyperdip47-50-C6other0.043470.95653 other
Hyperdip47-50-C7other0.012570.98743 other
Hyperdip47-50-C8other0.003110.99689 other
Hyperdip47-50-C9other0.005840.99416 other
Hypodip-1other0.010010.98999 other
Hypodip-2other0.076550.92345 other
Hypodip-2M1 (testset)other0.010970.98903 other
Hypodip-C1 (testset)other0.02140.9786 other
Hypodip-C2other0.028750.97125 other
Hypodip-C3other0.003560.99644 other
Hypodip-C4other0.051440.94856 other
Hypodip-C5 (testset)other0.003760.99624 other
Hypodip-C6 (testset)other0.004490.99551 other
MLL-1MLL0.603540.39646 MLL
MLL-2 (testset)MLL0.323770.67623 other
MLL-3 (testset)MLL0.995750.00425 MLL
MLL-4MLL0.441040.55896 other
MLL-5 (testset)MLL0.057750.94225 other
MLL-6 (testset)MLL0.04420.9558 other
MLL-7MLL0.06870.9313 other
MLL-8MLL0.185110.81489 other
MLL-2M1 (testset)MLL0.688390.31161 MLL
MLL-2M2MLL0.770150.22985 MLL
MLL-C1MLL0.982070.01793 MLL
MLL-C2 (testset)MLL0.303670.69633 other
MLL-C3MLL0.939580.06042 MLL
MLL-C4MLL0.064970.93503 other
MLL-C5MLL0.915540.08446 MLL
MLL-C6MLL0.495960.50404 other
MLL-R1MLL0.116040.88396 other
MLL-R2MLL0.378830.62117 other
MLL-R3MLL0.999480.00052 MLL
MLL-R4 (testset)MLL0.032440.96756 other
Normal-1other0.006210.99379 other
Normal-2other0.307310.69269 other
Normal-3other0.004990.99501 other
Normal-C1-N (testset)other0.006850.99315 other
Normal-C10 (testset)other0.018940.98106 other
Normal-C11-Nother0.011160.98884 other
Normal-C12other0.01010.9899 other
Normal-C2-Nother0.002340.99766 other
Normal-C3-Nother0.007110.99289 other
Normal-C4-Nother0.045750.95425 other
Normal-C5 (testset)other0.027970.97203 other
Normal-C6 (testset)other0.005170.99483 other
Normal-C7-Nother0.003120.99688 other
Normal-C8other0.007610.99239 other
Normal-C9other0.013390.98661 other
Normal-R1 (testset)other0.022190.97781 other
Normal-R2-Nother0.006240.99376 other
Normal-R3other0.022250.97775 other
Pseudodip-1other0.003380.99662 other
Pseudodip-2 (testset)other0.003310.99669 other
Pseudodip-3other0.032490.96751 other
Pseudodip-4other0.013390.98661 other
Pseudodip-5other0.017180.98282 other
Pseudodip-6other0.010520.98948 other
Pseudodip-7other0.08980.9102 other
Pseudodip-8-Nother0.008090.99191 other
Pseudodip-9 (testset)other0.014460.98554 other
Pseudodip-C10other0.002060.99794 other
Pseudodip-C11other0.009370.99063 other
Pseudodip-C12other0.002090.99791 other
Pseudodip-C13other0.00430.9957 other
Pseudodip-C14other0.005420.99458 other
Pseudodip-C15other0.004120.99588 other
Pseudodip-C16-N (testset)other0.001210.99879 other
Pseudodip-C17other0.011050.98895 other
Pseudodip-C18other0.012250.98775 other
Pseudodip-C19other0.064080.93592 other
Pseudodip-C1other0.012270.98773 other
Pseudodip-C2-Nother0.002160.99784 other
Pseudodip-C3other0.012950.98705 other
Pseudodip-C4 (testset)other0.00220.9978 other
Pseudodip-C5other0.009080.99092 other
Pseudodip-C6other0.016340.98366 other
Pseudodip-C7other0.007870.99213 other
Pseudodip-C8other0.003920.99608 other
Pseudodip-C9other0.033590.96641 other
Pseudodip-R1-N (testset)other0.002180.99782 other
T-ALL-10other0.041450.95855 other
T-ALL-1other0.176010.82399 other
T-ALL-2other0.050550.94945 other
T-ALL-3 (testset)other0.041540.95846 other
T-ALL-4 (testset)other0.02420.9758 other
T-ALL-5 (testset)other0.249220.75078 other
T-ALL-6 (testset)other0.126390.87361 other
T-ALL-7other0.089680.91032 other
T-ALL-8other0.050340.94966 other
T-ALL-9other0.008960.99104 other
T-ALL-2M1 (testset)other0.127230.87277 other
T-ALL-C10other0.123590.87641 other
T-ALL-C11other0.097350.90265 other
T-ALL-C12other0.088320.91168 other
T-ALL-C13other0.032930.96707 other
T-ALL-C14 (testset)other0.011310.98869 other
T-ALL-C15other0.150880.84912 other
T-ALL-C16 (testset)other0.020590.97941 other
T-ALL-C17 (testset)other0.042210.95779 other
T-ALL-C18other0.024820.97518 other
T-ALL-C19other0.082890.91711 other
T-ALL-C1 (testset)other0.027550.97245 other
T-ALL-C20other0.024750.97525 other
T-ALL-C21 (testset)other0.012540.98746 other
T-ALL-C22other0.060290.93971 other
T-ALL-C23other0.009820.99018 other
T-ALL-C24 (testset)other0.086420.91358 other
T-ALL-C25other0.265350.73465 other
T-ALL-C26other0.006980.99302 other
T-ALL-C2other0.082020.91798 other
T-ALL-C3 (testset)other0.010360.98964 other
T-ALL-C4other0.019050.98095 other
T-ALL-C5other0.05980.9402 other
T-ALL-C6other0.048030.95197 other
T-ALL-C7other0.029140.97086 other
T-ALL-C8other0.018540.98146 other
T-ALL-C9other0.0550.945 other
T-ALL-R1 (testset)other0.022940.97706 other
T-ALL-R2other0.186060.81394 other
T-ALL-R3other0.009190.99081 other
T-ALL-R4other0.088870.91113 other
T-ALL-R5 (testset)other0.092360.90764 other
T-ALL-R6 (testset)other0.131510.86849 other
TEL-AML1-10other0.001230.99877 other
TEL-AML1-11 (testset)other0.001070.99893 other
TEL-AML1-12other0.004490.99551 other
TEL-AML1-13other0.007760.99224 other
TEL-AML1-14other0.003730.99627 other
TEL-AML1-1other0.002710.99729 other
TEL-AML1-2 (testset)other0.004820.99518 other
TEL-AML1-3other0.000970.99903 other
TEL-AML1-4 (testset)other0.001240.99876 other
TEL-AML1-5 (testset)other0.008290.99171 other
TEL-AML1-6 (testset)other0.005410.99459 other
TEL-AML1-7other0.012390.98761 other
TEL-AML1-8 (testset)other0.003170.99683 other
TEL-AML1-9 (testset)other0.00330.9967 other
TEL-AML1-2M1other0.004890.99511 other
TEL-AML1-2M2 (testset)other0.009410.99059 other
TEL-AML1-2M3other0.001840.99816 other
TEL-AML1-2M4other0.004460.99554 other
TEL-AML1-2M5other0.002960.99704 other
TEL-AML1-C10 (testset)other0.01130.9887 other
TEL-AML1-C11 (testset)other0.000590.99941 other
TEL-AML1-C12 (testset)other0.005650.99435 other
TEL-AML1-C13 (testset)other0.002460.99754 other
TEL-AML1-C14other0.001180.99882 other
TEL-AML1-C15other0.002640.99736 other
TEL-AML1-C16other0.011230.98877 other
TEL-AML1-C17other0.012330.98767 other
TEL-AML1-C18other0.003730.99627 other
TEL-AML1-C19other0.006110.99389 other
TEL-AML1-C1other0.002890.99711 other
TEL-AML1-C20other0.003120.99688 other
TEL-AML1-C21 (testset)other0.004760.99524 other
TEL-AML1-C22 (testset)other0.000540.99946 other
TEL-AML1-C23other0.010670.98933 other
TEL-AML1-C24other0.001750.99825 other
TEL-AML1-C25other0.00490.9951 other
TEL-AML1-C26 (testset)other0.003630.99637 other
TEL-AML1-C27other0.001340.99866 other
TEL-AML1-C28 (testset)other0.0060.994 other
TEL-AML1-C29other0.002150.99785 other
TEL-AML1-C2other0.001160.99884 other
TEL-AML1-C30 (testset)other0.006040.99396 other
TEL-AML1-C31 (testset)other0.002250.99775 other
TEL-AML1-C32other0.002270.99773 other
TEL-AML1-C33other0.001660.99834 other
TEL-AML1-C34 (testset)other0.000670.99933 other
TEL-AML1-C35 (testset)other0.006690.99331 other
TEL-AML1-C36other0.002330.99767 other
TEL-AML1-C37 (testset)other4e-040.9996 other
TEL-AML1-C38other0.002390.99761 other
TEL-AML1-C39other0.002240.99776 other
TEL-AML1-C3other0.006840.99316 other
TEL-AML1-C40 (testset)other0.001450.99855 other
TEL-AML1-C41other0.001220.99878 other
TEL-AML1-C42 (testset)other0.004070.99593 other
TEL-AML1-C43other0.003370.99663 other
TEL-AML1-C44other0.004630.99537 other
TEL-AML1-C45other0.01990.9801 other
TEL-AML1-C46 (testset)other0.002750.99725 other
TEL-AML1-C47other0.002910.99709 other
TEL-AML1-C48other0.006390.99361 other
TEL-AML1-C49 (testset)other0.012430.98757 other
TEL-AML1-C4 (testset)other0.013070.98693 other
TEL-AML1-C50 (testset)other0.001680.99832 other
TEL-AML1-C51other0.001160.99884 other
TEL-AML1-C52other0.000880.99912 other
TEL-AML1-C53 (testset)other0.00510.9949 other
TEL-AML1-C54 (testset)other0.005630.99437 other
TEL-AML1-C55other0.004430.99557 other
TEL-AML1-C56 (testset)other0.03140.9686 other
TEL-AML1-C57other0.001590.99841 other
TEL-AML1-C5other0.004850.99515 other
TEL-AML1-C6 (testset)other0.005960.99404 other
TEL-AML1-C7 (testset)other0.003810.99619 other
TEL-AML1-C8other0.007950.99205 other
TEL-AML1-C9other0.007340.99266 other
TEL-AML1-R1 (testset)other0.000740.99926 other
TEL-AML1-R2other0.00440.9956 other
TEL-AML1-R3other0.002040.99796 other

 


Generated by StAM on Wed Sep 8 11:57:40 2004