GO:0007242

GO:0007242

intracellular signaling cascade

Biological Process

Parent node

GO:0007165	signal transduction

8 child nodes

ID	Term	Weight
GO:0001508	regulation of action potential	0.00000
GO:0009755	hormone mediated signaling	0.00000
GO:0030522	intracellular receptor-mediated signaling pathway	0.00000
GO:0007263	nitric oxide mediated signal transduction	0.00000
GO:0007243	protein kinase cascade	0.00000
GO:0019932	second-messenger-mediated signaling	0.00000
GO:0007264	small GTPase mediated signal transduction	0.00000
GO:0007242a	intracellular signaling cascade (annotated genes)	1

Performance on training data

• Error rate: 0.02304
• Performance: 0.14528
• Redundancy: 4.06932

	Sensitivity	Specificity
MLL	0.92308	0.98039
other	0.98039	0.92308

Performance on test data

• Error rate: 0.03636
• Performance: 0.16707
• Redundancy: 4.03512

	Sensitivity	Specificity
MLL	0.71429	0.98058
other	0.98058	0.71429

Predictions

	Class	MLL	other	Predictionn
BCR-ABL-1 (testset)	other	0.06566	0.93434	other
BCR-ABL-2 (testset)	other	0.01324	0.98676	other
BCR-ABL-3	other	0.00371	0.99629	other
BCR-ABL-4	other	0.01444	0.98556	other
BCR-ABL-5 (testset)	other	0.01837	0.98163	other
BCR-ABL-6	other	0.0038	0.9962	other
BCR-ABL-7 (testset)	other	0.01413	0.98587	other
BCR-ABL-8 (testset)	other	0.34128	0.65872	other
BCR-ABL-9	other	0.00369	0.99631	other
BCR-ABL-C1 (testset)	other	0.02546	0.97454	other
BCR-ABL-Hyperdip-10	other	0.00217	0.99783	other
BCR-ABL-Hyperdip-R5	other	0.00526	0.99474	other
BCR-ABL-R1 (testset)	other	0.08579	0.91421	other
BCR-ABL-R2 (testset)	other	0.00109	0.99891	other
BCR-ABL-R3 (testset)	other	0.08987	0.91013	other
E2A-PBX1-10	other	0.11523	0.88477	other
E2A-PBX1-11	other	0.14038	0.85962	other
E2A-PBX1-12 (testset)	other	0.19444	0.80556	other
E2A-PBX1-13 (testset)	other	0.32902	0.67098	other
E2A-PBX1-1	other	0.42007	0.57993	other
E2A-PBX1-2	other	0.0649	0.9351	other
E2A-PBX1-3	other	0.06992	0.93008	other
E2A-PBX1-4	other	0.02181	0.97819	other
E2A-PBX1-5	other	0.09635	0.90365	other
E2A-PBX1-6 (testset)	other	0.45443	0.54557	other
E2A-PBX1-7 (testset)	other	0.02981	0.97019	other
E2A-PBX1-8 (testset)	other	0.0267	0.9733	other
E2A-PBX1-9	other	0.03609	0.96391	other
E2A-PBX1-2M1	other	0.29575	0.70425	other
E2A-PBX1-C10 (testset)	other	0.18511	0.81489	other
E2A-PBX1-C11	other	0.06616	0.93384	other
E2A-PBX1-C12	other	0.15196	0.84804	other
E2A-PBX1-C1	other	0.03123	0.96877	other
E2A-PBX1-C2 (testset)	other	0.03137	0.96863	other
E2A-PBX1-C3	other	0.24933	0.75067	other
E2A-PBX1-C4	other	0.25263	0.74737	other
E2A-PBX1-C5	other	0.1027	0.8973	other
E2A-PBX1-C6	other	0.40889	0.59111	other
E2A-PBX1-C7	other	0.31778	0.68222	other
E2A-PBX1-C8 (testset)	other	0.10024	0.89976	other
E2A-PBX1-C9	other	0.05924	0.94076	other
E2A-PBX1-R1 (testset)	other	0.17446	0.82554	other
Hyperdip-50-10	other	0.00124	0.99876	other
Hyperdip-50-11	other	0.00103	0.99897	other
Hyperdip-50-12	other	0.01439	0.98561	other
Hyperdip-50-13	other	0.00141	0.99859	other
Hyperdip-50-14	other	0.01312	0.98688	other
Hyperdip-50-1	other	0.00647	0.99353	other
Hyperdip-50-2	other	0.00514	0.99486	other
Hyperdip-50-3	other	0.00238	0.99762	other
Hyperdip-50-4	other	0.00132	0.99868	other
Hyperdip-50-5	other	0.01059	0.98941	other
Hyperdip-50-6	other	0.04768	0.95232	other
Hyperdip-50-7 (testset)	other	0.00332	0.99668	other
Hyperdip-50-8	other	0.15976	0.84024	other
Hyperdip-50-9 (testset)	other	0.01071	0.98929	other
Hyperdip-50-2M1	other	0.00324	0.99676	other
Hyperdip-50-2M2 (testset)	other	0.00202	0.99798	other
Hyperdip-50-C10 (testset)	other	0.00646	0.99354	other
Hyperdip-50-C11	other	0.07301	0.92699	other
Hyperdip-50-C12	other	0.01004	0.98996	other
Hyperdip-50-C13	other	0.00256	0.99744	other
Hyperdip-50-C14	other	0.02027	0.97973	other
Hyperdip-50-C15	other	0.00433	0.99567	other
Hyperdip-50-C16	other	0.01548	0.98452	other
Hyperdip-50-C17	other	0.09862	0.90138	other
Hyperdip-50-C18 (testset)	other	0.0238	0.9762	other
Hyperdip-50-C19	other	0.00092	0.99908	other
Hyperdip-50-C1 (testset)	other	0.01019	0.98981	other
Hyperdip-50-C20	other	0.00475	0.99525	other
Hyperdip-50-C21	other	2e-04	0.9998	other
Hyperdip-50-C22	other	0.00386	0.99614	other
Hyperdip-50-C23 (testset)	other	0.00253	0.99747	other
Hyperdip-50-C24	other	0.00317	0.99683	other
Hyperdip-50-C25 (testset)	other	0.03282	0.96718	other
Hyperdip-50-C26 (testset)	other	0.003	0.997	other
Hyperdip-50-C27-N	other	0.01812	0.98188	other
Hyperdip-50-C28	other	0.00732	0.99268	other
Hyperdip-50-C29	other	0.00313	0.99687	other
Hyperdip-50-C2	other	0.0019	0.9981	other
Hyperdip-50-C30 (testset)	other	0.02551	0.97449	other
Hyperdip-50-C31 (testset)	other	0.00898	0.99102	other
Hyperdip-50-C32	other	0.0109	0.9891	other
Hyperdip-50-C33	other	0.00598	0.99402	other
Hyperdip-50-C34	other	9e-05	0.99991	other
Hyperdip-50-C35	other	0.00096	0.99904	other
Hyperdip-50-C36 (testset)	other	0.00439	0.99561	other
Hyperdip-50-C37	other	0.0044	0.9956	other
Hyperdip-50-C38	other	0.00116	0.99884	other
Hyperdip-50-C39	other	0.00254	0.99746	other
Hyperdip-50-C3 (testset)	other	0.00306	0.99694	other
Hyperdip-50-C40 (testset)	other	0.00811	0.99189	other
Hyperdip-50-C41	other	0.00482	0.99518	other
Hyperdip-50-C42 (testset)	other	0.00193	0.99807	other
Hyperdip-50-C43 (testset)	other	0.01534	0.98466	other
Hyperdip-50-C4	other	0.00383	0.99617	other
Hyperdip-50-C5	other	0.00284	0.99716	other
Hyperdip-50-C6 (testset)	other	0.01452	0.98548	other
Hyperdip-50-C7	other	0.00631	0.99369	other
Hyperdip-50-C8	other	0.01437	0.98563	other
Hyperdip-50-C9	other	0.00899	0.99101	other
Hyperdip-50-R1 (testset)	other	0.00106	0.99894	other
Hyperdip-50-R2	other	0.0031	0.9969	other
Hyperdip-50-R3 (testset)	other	0.00981	0.99019	other
Hyperdip-50-R4	other	0.00166	0.99834	other
Hyperdip-50-R5 (testset)	other	0.00381	0.99619	other
Hyperdip47-50-1	other	0.01444	0.98556	other
Hyperdip47-50-2	other	0.00339	0.99661	other
Hyperdip47-50-3	other	0.09023	0.90977	other
Hyperdip47-50-2M1	other	0.00315	0.99685	other
Hyperdip47-50-C10 (testset)	other	0.00494	0.99506	other
Hyperdip47-50-C11	other	0.00097	0.99903	other
Hyperdip47-50-C12	other	0.00336	0.99664	other
Hyperdip47-50-C13	other	0.66663	0.33337	MLL
Hyperdip47-50-C14-N	other	0.00137	0.99863	other
Hyperdip47-50-C15	other	0.00592	0.99408	other
Hyperdip47-50-C16 (testset)	other	0.53181	0.46819	MLL
Hyperdip47-50-C17	other	0.03386	0.96614	other
Hyperdip47-50-C18	other	0.04907	0.95093	other
Hyperdip47-50-C19	other	0.01362	0.98638	other
Hyperdip47-50-C1 (testset)	other	0.21965	0.78035	other
Hyperdip47-50-C2	other	0.0018	0.9982	other
Hyperdip47-50-C3-N	other	0.05191	0.94809	other
Hyperdip47-50-C4	other	0.02582	0.97418	other
Hyperdip47-50-C5	other	0.04652	0.95348	other
Hyperdip47-50-C6	other	0.00077	0.99923	other
Hyperdip47-50-C7	other	0.02525	0.97475	other
Hyperdip47-50-C8	other	0.00327	0.99673	other
Hyperdip47-50-C9	other	0.05877	0.94123	other
Hypodip-1	other	0.25062	0.74938	other
Hypodip-2	other	0.01161	0.98839	other
Hypodip-2M1 (testset)	other	0.0114	0.9886	other
Hypodip-C1 (testset)	other	0.01876	0.98124	other
Hypodip-C2	other	0.06391	0.93609	other
Hypodip-C3	other	0.02012	0.97988	other
Hypodip-C4	other	0.10299	0.89701	other
Hypodip-C5 (testset)	other	0.00808	0.99192	other
Hypodip-C6 (testset)	other	0.20245	0.79755	other
MLL-1	MLL	0.93281	0.06719	MLL
MLL-2 (testset)	MLL	0.30437	0.69563	other
MLL-3 (testset)	MLL	0.99725	0.00275	MLL
MLL-4	MLL	0.99056	0.00944	MLL
MLL-5 (testset)	MLL	0.96981	0.03019	MLL
MLL-6 (testset)	MLL	0.97606	0.02394	MLL
MLL-7	MLL	0.81223	0.18777	MLL
MLL-8	MLL	0.84894	0.15106	MLL
MLL-2M1 (testset)	MLL	0.11583	0.88417	other
MLL-2M2	MLL	0.99968	0.00032	MLL
MLL-C1	MLL	0.9954	0.0046	MLL
MLL-C2 (testset)	MLL	0.99434	0.00566	MLL
MLL-C3	MLL	0.70493	0.29507	MLL
MLL-C4	MLL	0.90163	0.09837	MLL
MLL-C5	MLL	0.77435	0.22565	MLL
MLL-C6	MLL	0.61132	0.38868	MLL
MLL-R1	MLL	0.4666	0.5334	other
MLL-R2	MLL	0.98127	0.01873	MLL
MLL-R3	MLL	0.9904	0.0096	MLL
MLL-R4 (testset)	MLL	0.81452	0.18548	MLL
Normal-1	other	0.01613	0.98387	other
Normal-2	other	0.69856	0.30144	MLL
Normal-3	other	0.0064	0.9936	other
Normal-C1-N (testset)	other	0.05254	0.94746	other
Normal-C10 (testset)	other	0.06133	0.93867	other
Normal-C11-N	other	0.00569	0.99431	other
Normal-C12	other	0.03342	0.96658	other
Normal-C2-N	other	0.00576	0.99424	other
Normal-C3-N	other	0.00412	0.99588	other
Normal-C4-N	other	0.00425	0.99575	other
Normal-C5 (testset)	other	0.057	0.943	other
Normal-C6 (testset)	other	0.0048	0.9952	other
Normal-C7-N	other	0.00773	0.99227	other
Normal-C8	other	0.72527	0.27473	MLL
Normal-C9	other	0.02523	0.97477	other
Normal-R1 (testset)	other	0.70992	0.29008	MLL
Normal-R2-N	other	0.04362	0.95638	other
Normal-R3	other	0.00941	0.99059	other
Pseudodip-1	other	0.05349	0.94651	other
Pseudodip-2 (testset)	other	0.00286	0.99714	other
Pseudodip-3	other	0.02635	0.97365	other
Pseudodip-4	other	0.01055	0.98945	other
Pseudodip-5	other	0.01047	0.98953	other
Pseudodip-6	other	0.09465	0.90535	other
Pseudodip-7	other	0.00781	0.99219	other
Pseudodip-8-N	other	0.23905	0.76095	other
Pseudodip-9 (testset)	other	0.08397	0.91603	other
Pseudodip-C10	other	0.02172	0.97828	other
Pseudodip-C11	other	0.00829	0.99171	other
Pseudodip-C12	other	0.00074	0.99926	other
Pseudodip-C13	other	0.04201	0.95799	other
Pseudodip-C14	other	0.38505	0.61495	other
Pseudodip-C15	other	0.00573	0.99427	other
Pseudodip-C16-N (testset)	other	0.03164	0.96836	other
Pseudodip-C17	other	0.00339	0.99661	other
Pseudodip-C18	other	0.03883	0.96117	other
Pseudodip-C19	other	0.17629	0.82371	other
Pseudodip-C1	other	0.10494	0.89506	other
Pseudodip-C2-N	other	0.00839	0.99161	other
Pseudodip-C3	other	0.06591	0.93409	other
Pseudodip-C4 (testset)	other	0.00486	0.99514	other
Pseudodip-C5	other	0.09108	0.90892	other
Pseudodip-C6	other	0.23117	0.76883	other
Pseudodip-C7	other	0.02579	0.97421	other
Pseudodip-C8	other	0.89111	0.10889	MLL
Pseudodip-C9	other	0.01158	0.98842	other
Pseudodip-R1-N (testset)	other	0.03339	0.96661	other
T-ALL-10	other	0.00052	0.99948	other
T-ALL-1	other	1e-05	0.99999	other
T-ALL-2	other	0.00148	0.99852	other
T-ALL-3 (testset)	other	0.00011	0.99989	other
T-ALL-4 (testset)	other	7e-05	0.99993	other
T-ALL-5 (testset)	other	9e-05	0.99991	other
T-ALL-6 (testset)	other	2e-05	0.99998	other
T-ALL-7	other	0.00019	0.99981	other
T-ALL-8	other	3e-05	0.99997	other
T-ALL-9	other	0.00044	0.99956	other
T-ALL-2M1 (testset)	other	0.00021	0.99979	other
T-ALL-C10	other	3e-05	0.99997	other
T-ALL-C11	other	1e-05	0.99999	other
T-ALL-C12	other	0	1	other
T-ALL-C13	other	3e-05	0.99997	other
T-ALL-C14 (testset)	other	0.00034	0.99966	other
T-ALL-C15	other	5e-05	0.99995	other
T-ALL-C16 (testset)	other	5e-05	0.99995	other
T-ALL-C17 (testset)	other	0.00416	0.99584	other
T-ALL-C18	other	0.23572	0.76428	other
T-ALL-C19	other	5e-05	0.99995	other
T-ALL-C1 (testset)	other	0.00043	0.99957	other
T-ALL-C20	other	1e-05	0.99999	other
T-ALL-C21 (testset)	other	0.00035	0.99965	other
T-ALL-C22	other	9e-05	0.99991	other
T-ALL-C23	other	0.00034	0.99966	other
T-ALL-C24 (testset)	other	7e-05	0.99993	other
T-ALL-C25	other	2e-05	0.99998	other
T-ALL-C26	other	0.00012	0.99988	other
T-ALL-C2	other	2e-05	0.99998	other
T-ALL-C3 (testset)	other	0	1	other
T-ALL-C4	other	0.00024	0.99976	other
T-ALL-C5	other	0.06543	0.93457	other
T-ALL-C6	other	0.00015	0.99985	other
T-ALL-C7	other	0.00016	0.99984	other
T-ALL-C8	other	0.00069	0.99931	other
T-ALL-C9	other	3e-05	0.99997	other
T-ALL-R1 (testset)	other	4e-05	0.99996	other
T-ALL-R2	other	6e-05	0.99994	other
T-ALL-R3	other	0	1	other
T-ALL-R4	other	2e-05	0.99998	other
T-ALL-R5 (testset)	other	0.00062	0.99938	other
T-ALL-R6 (testset)	other	0.00064	0.99936	other
TEL-AML1-10	other	0.00462	0.99538	other
TEL-AML1-11 (testset)	other	0.00476	0.99524	other
TEL-AML1-12	other	0.0023	0.9977	other
TEL-AML1-13	other	0.00221	0.99779	other
TEL-AML1-14	other	0.00304	0.99696	other
TEL-AML1-1	other	0.00079	0.99921	other
TEL-AML1-2 (testset)	other	0.00603	0.99397	other
TEL-AML1-3	other	0.00301	0.99699	other
TEL-AML1-4 (testset)	other	0.0031	0.9969	other
TEL-AML1-5 (testset)	other	0.00739	0.99261	other
TEL-AML1-6 (testset)	other	0.0284	0.9716	other
TEL-AML1-7	other	0.00625	0.99375	other
TEL-AML1-8 (testset)	other	0.00173	0.99827	other
TEL-AML1-9 (testset)	other	0.00333	0.99667	other
TEL-AML1-2M1	other	0.00888	0.99112	other
TEL-AML1-2M2 (testset)	other	0.0094	0.9906	other
TEL-AML1-2M3	other	0.00118	0.99882	other
TEL-AML1-2M4	other	0.00278	0.99722	other
TEL-AML1-2M5	other	0.00101	0.99899	other
TEL-AML1-C10 (testset)	other	0.00028	0.99972	other
TEL-AML1-C11 (testset)	other	0.02723	0.97277	other
TEL-AML1-C12 (testset)	other	0.00105	0.99895	other
TEL-AML1-C13 (testset)	other	0.00253	0.99747	other
TEL-AML1-C14	other	0.00614	0.99386	other
TEL-AML1-C15	other	0.00102	0.99898	other
TEL-AML1-C16	other	0.01246	0.98754	other
TEL-AML1-C17	other	0.00198	0.99802	other
TEL-AML1-C18	other	0.00682	0.99318	other
TEL-AML1-C19	other	0.00024	0.99976	other
TEL-AML1-C1	other	0.00082	0.99918	other
TEL-AML1-C20	other	0.00218	0.99782	other
TEL-AML1-C21 (testset)	other	0.00137	0.99863	other
TEL-AML1-C22 (testset)	other	0.00029	0.99971	other
TEL-AML1-C23	other	0.00625	0.99375	other
TEL-AML1-C24	other	0.00294	0.99706	other
TEL-AML1-C25	other	0.00317	0.99683	other
TEL-AML1-C26 (testset)	other	0.00425	0.99575	other
TEL-AML1-C27	other	0.00059	0.99941	other
TEL-AML1-C28 (testset)	other	0.00261	0.99739	other
TEL-AML1-C29	other	0.00051	0.99949	other
TEL-AML1-C2	other	0.00024	0.99976	other
TEL-AML1-C30 (testset)	other	0.00174	0.99826	other
TEL-AML1-C31 (testset)	other	0.0015	0.9985	other
TEL-AML1-C32	other	0.00053	0.99947	other
TEL-AML1-C33	other	0.00243	0.99757	other
TEL-AML1-C34 (testset)	other	0.00151	0.99849	other
TEL-AML1-C35 (testset)	other	0.00937	0.99063	other
TEL-AML1-C36	other	0.00124	0.99876	other
TEL-AML1-C37 (testset)	other	0.00091	0.99909	other
TEL-AML1-C38	other	0.00032	0.99968	other
TEL-AML1-C39	other	0.00345	0.99655	other
TEL-AML1-C3	other	0.00243	0.99757	other
TEL-AML1-C40 (testset)	other	0.00089	0.99911	other
TEL-AML1-C41	other	0.00106	0.99894	other
TEL-AML1-C42 (testset)	other	0.00036	0.99964	other
TEL-AML1-C43	other	0.00709	0.99291	other
TEL-AML1-C44	other	0.00274	0.99726	other
TEL-AML1-C45	other	0.00255	0.99745	other
TEL-AML1-C46 (testset)	other	0.01036	0.98964	other
TEL-AML1-C47	other	0.00168	0.99832	other
TEL-AML1-C48	other	0.00162	0.99838	other
TEL-AML1-C49 (testset)	other	0.00174	0.99826	other
TEL-AML1-C4 (testset)	other	0.00337	0.99663	other
TEL-AML1-C50 (testset)	other	0.00308	0.99692	other
TEL-AML1-C51	other	0.00105	0.99895	other
TEL-AML1-C52	other	0.00294	0.99706	other
TEL-AML1-C53 (testset)	other	0.00124	0.99876	other
TEL-AML1-C54 (testset)	other	0.00116	0.99884	other
TEL-AML1-C55	other	0.0063	0.9937	other
TEL-AML1-C56 (testset)	other	0.00612	0.99388	other
TEL-AML1-C57	other	0.00032	0.99968	other
TEL-AML1-C5	other	0.00363	0.99637	other
TEL-AML1-C6 (testset)	other	0.001	0.999	other
TEL-AML1-C7 (testset)	other	0.00129	0.99871	other
TEL-AML1-C8	other	0.0023	0.9977	other
TEL-AML1-C9	other	0.00346	0.99654	other
TEL-AML1-R1 (testset)	other	0.002	0.998	other
TEL-AML1-R2	other	0.00257	0.99743	other
TEL-AML1-R3	other	0.00707	0.99293	other