GO:0007165

GO:0007165

signal transduction (annotated genes)

Biological Process

Parent node

GO:0007165	signal transduction

This leaf node contains 959 genes

The following 30 of these are used in classification:

	Symbol	Genename	MLL score	other score
38291_at	PENK	proenkephalin	0.6766	-0.0431
36777_at	KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.585	-0.0373
36873_at	VLDLR	very low density lipoprotein receptor	0.5305	-0.0338
32207_at	MPP1	membrane protein, palmitoylated 1, 55kDa	-0.4539	0.0289
37280_at	MADH1	MAD, mothers against decapentaplegic homolog 1 (Drosophila)	-0.416	0.0265
577_at	MDK	midkine (neurite growth-promoting factor 2)	-0.3364	0.0214
914_g_at	ERG	v-ets erythroblastosis virus E26 oncogene like (avian)	-0.2798	0.0178
38124_at	MDK	midkine (neurite growth-promoting factor 2)	-0.2672	0.017
1520_s_at	IL1B	interleukin 1, beta	-0.262	0.0167
1325_at	MADH1	MAD, mothers against decapentaplegic homolog 1 (Drosophila)	-0.2363	0.0151
38053_s_at	BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)	0.2361	-0.015
33705_at	PDE4B	phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)	-0.1958	0.0125
36383_at	ERG	v-ets erythroblastosis virus E26 oncogene like (avian)	-0.156	0.0099
37398_at	PECAM1	platelet/endothelial cell adhesion molecule (CD31 antigen)	-0.1354	0.0086
1039_s_at	HIF1A	hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	-0.0918	0.0058
32806_at	BZRP	benzodiazapine receptor (peripheral)	0.0887	-0.0057
913_at	ERG	v-ets erythroblastosis virus E26 oncogene like (avian)	-0.0851	0.0054
39402_at	IL1B	interleukin 1, beta	-0.0716	0.0046
35238_at	TRAF5	TNF receptor-associated factor 5	-0.0626	0.004
36798_g_at	SPN	sialophorin (gpL115, leukosialin, CD43)	0.0622	-0.004
1102_s_at	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.0494	-0.0031
40785_g_at	PPP2R5C	protein phosphatase 2, regulatory subunit B (B56), gamma isoform	0.0493	-0.0031
39781_at	IGFBP4	insulin-like growth factor binding protein 4	-0.0456	0.0029
38968_at	SH3BP5	SH3-domain binding protein 5 (BTK-associated)	-0.0361	0.0023
40049_at	DAPK1	death-associated protein kinase 1	-0.0358	0.0023
37754_at	LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein	-0.0251	0.0016
1453_at	MADH2	MAD, mothers against decapentaplegic homolog 2 (Drosophila)	-0.0244	0.0016
755_at	ITPR1	inositol 1,4,5-triphosphate receptor, type 1	-0.0224	0.0014
34223_at	CSF3R	colony stimulating factor 3 receptor (granulocyte)	-0.0194	0.0012
32737_at	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.0094	-6e-04

Performance on training data

• Error rate: 0
• Performance: 0.12679
• Redundancy: 3.57631

	Sensitivity	Specificity
MLL	1	1
other	1	1

Performance on test data

• Error rate: 0
• Performance: 0.13798
• Redundancy: 3.57815

	Sensitivity	Specificity
MLL	1	1
other	1	1

Predictions

	Class	MLL	other	Predictionn
BCR-ABL-1 (testset)	other	0.10157	0.89843	other
BCR-ABL-2 (testset)	other	0.02604	0.97396	other
BCR-ABL-3	other	0.00334	0.99666	other
BCR-ABL-4	other	0.01059	0.98941	other
BCR-ABL-5 (testset)	other	0.05933	0.94067	other
BCR-ABL-6	other	0.00944	0.99056	other
BCR-ABL-7 (testset)	other	0.12589	0.87411	other
BCR-ABL-8 (testset)	other	0.08598	0.91402	other
BCR-ABL-9	other	0.00498	0.99502	other
BCR-ABL-C1 (testset)	other	0.03649	0.96351	other
BCR-ABL-Hyperdip-10	other	0.00125	0.99875	other
BCR-ABL-Hyperdip-R5	other	0.00072	0.99928	other
BCR-ABL-R1 (testset)	other	0.04397	0.95603	other
BCR-ABL-R2 (testset)	other	0.00179	0.99821	other
BCR-ABL-R3 (testset)	other	0.06557	0.93443	other
E2A-PBX1-10	other	0.0969	0.9031	other
E2A-PBX1-11	other	0.04658	0.95342	other
E2A-PBX1-12 (testset)	other	0.06712	0.93288	other
E2A-PBX1-13 (testset)	other	0.01022	0.98978	other
E2A-PBX1-1	other	0.01652	0.98348	other
E2A-PBX1-2	other	0.01948	0.98052	other
E2A-PBX1-3	other	0.0155	0.9845	other
E2A-PBX1-4	other	0.03312	0.96688	other
E2A-PBX1-5	other	0.01907	0.98093	other
E2A-PBX1-6 (testset)	other	0.02416	0.97584	other
E2A-PBX1-7 (testset)	other	0.05122	0.94878	other
E2A-PBX1-8 (testset)	other	0.0221	0.9779	other
E2A-PBX1-9	other	0.01071	0.98929	other
E2A-PBX1-2M1	other	0.05349	0.94651	other
E2A-PBX1-C10 (testset)	other	0.01343	0.98657	other
E2A-PBX1-C11	other	0.10301	0.89699	other
E2A-PBX1-C12	other	0.00959	0.99041	other
E2A-PBX1-C1	other	0.08105	0.91895	other
E2A-PBX1-C2 (testset)	other	0.03385	0.96615	other
E2A-PBX1-C3	other	0.09585	0.90415	other
E2A-PBX1-C4	other	0.01973	0.98027	other
E2A-PBX1-C5	other	0.13521	0.86479	other
E2A-PBX1-C6	other	0.04293	0.95707	other
E2A-PBX1-C7	other	0.07427	0.92573	other
E2A-PBX1-C8 (testset)	other	0.06422	0.93578	other
E2A-PBX1-C9	other	0.01653	0.98347	other
E2A-PBX1-R1 (testset)	other	0.0543	0.9457	other
Hyperdip-50-10	other	0.00144	0.99856	other
Hyperdip-50-11	other	0.00669	0.99331	other
Hyperdip-50-12	other	0.02094	0.97906	other
Hyperdip-50-13	other	0.00273	0.99727	other
Hyperdip-50-14	other	0.00062	0.99938	other
Hyperdip-50-1	other	0.00361	0.99639	other
Hyperdip-50-2	other	0.00229	0.99771	other
Hyperdip-50-3	other	0.00304	0.99696	other
Hyperdip-50-4	other	0.00515	0.99485	other
Hyperdip-50-5	other	0.00158	0.99842	other
Hyperdip-50-6	other	0.00094	0.99906	other
Hyperdip-50-7 (testset)	other	0.09721	0.90279	other
Hyperdip-50-8	other	0.00391	0.99609	other
Hyperdip-50-9 (testset)	other	0.00905	0.99095	other
Hyperdip-50-2M1	other	0.00679	0.99321	other
Hyperdip-50-2M2 (testset)	other	0.12606	0.87394	other
Hyperdip-50-C10 (testset)	other	0.00613	0.99387	other
Hyperdip-50-C11	other	0.00268	0.99732	other
Hyperdip-50-C12	other	0.0277	0.9723	other
Hyperdip-50-C13	other	0.00123	0.99877	other
Hyperdip-50-C14	other	0.013	0.987	other
Hyperdip-50-C15	other	0.00564	0.99436	other
Hyperdip-50-C16	other	0.02768	0.97232	other
Hyperdip-50-C17	other	0.0106	0.9894	other
Hyperdip-50-C18 (testset)	other	0.00686	0.99314	other
Hyperdip-50-C19	other	0.07899	0.92101	other
Hyperdip-50-C1 (testset)	other	0.00897	0.99103	other
Hyperdip-50-C20	other	0.00061	0.99939	other
Hyperdip-50-C21	other	0.00021	0.99979	other
Hyperdip-50-C22	other	0.0031	0.9969	other
Hyperdip-50-C23 (testset)	other	0.00596	0.99404	other
Hyperdip-50-C24	other	0.01	0.99	other
Hyperdip-50-C25 (testset)	other	0.00102	0.99898	other
Hyperdip-50-C26 (testset)	other	0.01901	0.98099	other
Hyperdip-50-C27-N	other	0.03936	0.96064	other
Hyperdip-50-C28	other	0.02917	0.97083	other
Hyperdip-50-C29	other	0.02812	0.97188	other
Hyperdip-50-C2	other	0.01097	0.98903	other
Hyperdip-50-C30 (testset)	other	0.00301	0.99699	other
Hyperdip-50-C31 (testset)	other	0.00048	0.99952	other
Hyperdip-50-C32	other	0.0036	0.9964	other
Hyperdip-50-C33	other	0.00789	0.99211	other
Hyperdip-50-C34	other	0.00153	0.99847	other
Hyperdip-50-C35	other	0.00351	0.99649	other
Hyperdip-50-C36 (testset)	other	0.00045	0.99955	other
Hyperdip-50-C37	other	0.01308	0.98692	other
Hyperdip-50-C38	other	0.00066	0.99934	other
Hyperdip-50-C39	other	0.00362	0.99638	other
Hyperdip-50-C3 (testset)	other	0.05005	0.94995	other
Hyperdip-50-C40 (testset)	other	0.01023	0.98977	other
Hyperdip-50-C41	other	0.00094	0.99906	other
Hyperdip-50-C42 (testset)	other	0.00106	0.99894	other
Hyperdip-50-C43 (testset)	other	0.02825	0.97175	other
Hyperdip-50-C4	other	0.00359	0.99641	other
Hyperdip-50-C5	other	0.02097	0.97903	other
Hyperdip-50-C6 (testset)	other	0.004	0.996	other
Hyperdip-50-C7	other	0.00596	0.99404	other
Hyperdip-50-C8	other	0.01764	0.98236	other
Hyperdip-50-C9	other	0.00304	0.99696	other
Hyperdip-50-R1 (testset)	other	0.00673	0.99327	other
Hyperdip-50-R2	other	0.00934	0.99066	other
Hyperdip-50-R3 (testset)	other	0.32549	0.67451	other
Hyperdip-50-R4	other	0.00571	0.99429	other
Hyperdip-50-R5 (testset)	other	0.00897	0.99103	other
Hyperdip47-50-1	other	0.00145	0.99855	other
Hyperdip47-50-2	other	0.0148	0.9852	other
Hyperdip47-50-3	other	0.35662	0.64338	other
Hyperdip47-50-2M1	other	0.00062	0.99938	other
Hyperdip47-50-C10 (testset)	other	0.00403	0.99597	other
Hyperdip47-50-C11	other	0.07306	0.92694	other
Hyperdip47-50-C12	other	0.0145	0.9855	other
Hyperdip47-50-C13	other	0.17144	0.82856	other
Hyperdip47-50-C14-N	other	0.00979	0.99021	other
Hyperdip47-50-C15	other	0.00573	0.99427	other
Hyperdip47-50-C16 (testset)	other	0.40553	0.59447	other
Hyperdip47-50-C17	other	0.00468	0.99532	other
Hyperdip47-50-C18	other	0.00638	0.99362	other
Hyperdip47-50-C19	other	0.08164	0.91836	other
Hyperdip47-50-C1 (testset)	other	0.22797	0.77203	other
Hyperdip47-50-C2	other	0.10343	0.89657	other
Hyperdip47-50-C3-N	other	0.0021	0.9979	other
Hyperdip47-50-C4	other	0.05113	0.94887	other
Hyperdip47-50-C5	other	0.10005	0.89995	other
Hyperdip47-50-C6	other	0.00045	0.99955	other
Hyperdip47-50-C7	other	0.06267	0.93733	other
Hyperdip47-50-C8	other	0.00301	0.99699	other
Hyperdip47-50-C9	other	0.00203	0.99797	other
Hypodip-1	other	0.05507	0.94493	other
Hypodip-2	other	0.05348	0.94652	other
Hypodip-2M1 (testset)	other	0.01261	0.98739	other
Hypodip-C1 (testset)	other	0.00191	0.99809	other
Hypodip-C2	other	0.14524	0.85476	other
Hypodip-C3	other	0.22415	0.77585	other
Hypodip-C4	other	0.40442	0.59558	other
Hypodip-C5 (testset)	other	0.02188	0.97812	other
Hypodip-C6 (testset)	other	0.07364	0.92636	other
MLL-1	MLL	0.94384	0.05616	MLL
MLL-2 (testset)	MLL	0.76633	0.23367	MLL
MLL-3 (testset)	MLL	0.95854	0.04146	MLL
MLL-4	MLL	0.94775	0.05225	MLL
MLL-5 (testset)	MLL	0.85509	0.14491	MLL
MLL-6 (testset)	MLL	0.84306	0.15694	MLL
MLL-7	MLL	0.85624	0.14376	MLL
MLL-8	MLL	0.58636	0.41364	MLL
MLL-2M1 (testset)	MLL	0.68786	0.31214	MLL
MLL-2M2	MLL	0.95165	0.04835	MLL
MLL-C1	MLL	0.87469	0.12531	MLL
MLL-C2 (testset)	MLL	0.58828	0.41172	MLL
MLL-C3	MLL	0.93407	0.06593	MLL
MLL-C4	MLL	0.76064	0.23936	MLL
MLL-C5	MLL	0.99365	0.00635	MLL
MLL-C6	MLL	0.93016	0.06984	MLL
MLL-R1	MLL	0.68738	0.31262	MLL
MLL-R2	MLL	0.66339	0.33661	MLL
MLL-R3	MLL	0.86949	0.13051	MLL
MLL-R4 (testset)	MLL	0.74346	0.25654	MLL
Normal-1	other	0.0701	0.9299	other
Normal-2	other	0.13579	0.86421	other
Normal-3	other	0.0138	0.9862	other
Normal-C1-N (testset)	other	0.03699	0.96301	other
Normal-C10 (testset)	other	0.21495	0.78505	other
Normal-C11-N	other	0.03411	0.96589	other
Normal-C12	other	0.06151	0.93849	other
Normal-C2-N	other	0.05007	0.94993	other
Normal-C3-N	other	0.13291	0.86709	other
Normal-C4-N	other	0.01515	0.98485	other
Normal-C5 (testset)	other	0.01052	0.98948	other
Normal-C6 (testset)	other	0.02889	0.97111	other
Normal-C7-N	other	0.09025	0.90975	other
Normal-C8	other	0.30039	0.69961	other
Normal-C9	other	0.01568	0.98432	other
Normal-R1 (testset)	other	0.12993	0.87007	other
Normal-R2-N	other	0.00555	0.99445	other
Normal-R3	other	0.0647	0.9353	other
Pseudodip-1	other	0.05679	0.94321	other
Pseudodip-2 (testset)	other	0.00258	0.99742	other
Pseudodip-3	other	0.042	0.958	other
Pseudodip-4	other	0.04089	0.95911	other
Pseudodip-5	other	0.01319	0.98681	other
Pseudodip-6	other	0.00843	0.99157	other
Pseudodip-7	other	0.01083	0.98917	other
Pseudodip-8-N	other	0.0708	0.9292	other
Pseudodip-9 (testset)	other	0.04962	0.95038	other
Pseudodip-C10	other	0.00139	0.99861	other
Pseudodip-C11	other	0.01001	0.98999	other
Pseudodip-C12	other	0.02345	0.97655	other
Pseudodip-C13	other	0.02407	0.97593	other
Pseudodip-C14	other	0.18468	0.81532	other
Pseudodip-C15	other	0.03067	0.96933	other
Pseudodip-C16-N (testset)	other	0.01617	0.98383	other
Pseudodip-C17	other	0.00656	0.99344	other
Pseudodip-C18	other	0.06053	0.93947	other
Pseudodip-C19	other	0.02199	0.97801	other
Pseudodip-C1	other	0.00981	0.99019	other
Pseudodip-C2-N	other	0.03462	0.96538	other
Pseudodip-C3	other	0.13977	0.86023	other
Pseudodip-C4 (testset)	other	0.25468	0.74532	other
Pseudodip-C5	other	0.23755	0.76245	other
Pseudodip-C6	other	0.13311	0.86689	other
Pseudodip-C7	other	0.05071	0.94929	other
Pseudodip-C8	other	0.03833	0.96167	other
Pseudodip-C9	other	0.03809	0.96191	other
Pseudodip-R1-N (testset)	other	0.01124	0.98876	other
T-ALL-10	other	0.0743	0.9257	other
T-ALL-1	other	0.13201	0.86799	other
T-ALL-2	other	0.35089	0.64911	other
T-ALL-3 (testset)	other	0.15207	0.84793	other
T-ALL-4 (testset)	other	0.24297	0.75703	other
T-ALL-5 (testset)	other	0.11218	0.88782	other
T-ALL-6 (testset)	other	0.02974	0.97026	other
T-ALL-7	other	0.23352	0.76648	other
T-ALL-8	other	0.22459	0.77541	other
T-ALL-9	other	0.09052	0.90948	other
T-ALL-2M1 (testset)	other	0.18762	0.81238	other
T-ALL-C10	other	0.17655	0.82345	other
T-ALL-C11	other	0.07517	0.92483	other
T-ALL-C12	other	0.14768	0.85232	other
T-ALL-C13	other	0.11262	0.88738	other
T-ALL-C14 (testset)	other	0.25219	0.74781	other
T-ALL-C15	other	0.19941	0.80059	other
T-ALL-C16 (testset)	other	0.16479	0.83521	other
T-ALL-C17 (testset)	other	0.1341	0.8659	other
T-ALL-C18	other	0.16037	0.83963	other
T-ALL-C19	other	0.19286	0.80714	other
T-ALL-C1 (testset)	other	0.13304	0.86696	other
T-ALL-C20	other	0.15324	0.84676	other
T-ALL-C21 (testset)	other	0.11961	0.88039	other
T-ALL-C22	other	0.06572	0.93428	other
T-ALL-C23	other	0.09455	0.90545	other
T-ALL-C24 (testset)	other	0.21335	0.78665	other
T-ALL-C25	other	0.07464	0.92536	other
T-ALL-C26	other	0.27945	0.72055	other
T-ALL-C2	other	0.17491	0.82509	other
T-ALL-C3 (testset)	other	0.09045	0.90955	other
T-ALL-C4	other	0.1978	0.8022	other
T-ALL-C5	other	0.14691	0.85309	other
T-ALL-C6	other	0.12078	0.87922	other
T-ALL-C7	other	0.05543	0.94457	other
T-ALL-C8	other	0.32118	0.67882	other
T-ALL-C9	other	0.15521	0.84479	other
T-ALL-R1 (testset)	other	0.03409	0.96591	other
T-ALL-R2	other	0.03482	0.96518	other
T-ALL-R3	other	0.19081	0.80919	other
T-ALL-R4	other	0.08545	0.91455	other
T-ALL-R5 (testset)	other	0.0198	0.9802	other
T-ALL-R6 (testset)	other	0.1065	0.8935	other
TEL-AML1-10	other	0.00022	0.99978	other
TEL-AML1-11 (testset)	other	0.01077	0.98923	other
TEL-AML1-12	other	0.00278	0.99722	other
TEL-AML1-13	other	0.00287	0.99713	other
TEL-AML1-14	other	0.00202	0.99798	other
TEL-AML1-1	other	0.02533	0.97467	other
TEL-AML1-2 (testset)	other	0.0037	0.9963	other
TEL-AML1-3	other	0.00179	0.99821	other
TEL-AML1-4 (testset)	other	0.00593	0.99407	other
TEL-AML1-5 (testset)	other	0.00563	0.99437	other
TEL-AML1-6 (testset)	other	0.00529	0.99471	other
TEL-AML1-7	other	0.00053	0.99947	other
TEL-AML1-8 (testset)	other	0.00212	0.99788	other
TEL-AML1-9 (testset)	other	0.0014	0.9986	other
TEL-AML1-2M1	other	0.00168	0.99832	other
TEL-AML1-2M2 (testset)	other	0.0054	0.9946	other
TEL-AML1-2M3	other	0.03002	0.96998	other
TEL-AML1-2M4	other	0.00673	0.99327	other
TEL-AML1-2M5	other	0.0092	0.9908	other
TEL-AML1-C10 (testset)	other	0.00691	0.99309	other
TEL-AML1-C11 (testset)	other	0.02526	0.97474	other
TEL-AML1-C12 (testset)	other	0.00287	0.99713	other
TEL-AML1-C13 (testset)	other	0.00407	0.99593	other
TEL-AML1-C14	other	0.00282	0.99718	other
TEL-AML1-C15	other	0.00023	0.99977	other
TEL-AML1-C16	other	0.00505	0.99495	other
TEL-AML1-C17	other	0.02161	0.97839	other
TEL-AML1-C18	other	0.00387	0.99613	other
TEL-AML1-C19	other	0.0025	0.9975	other
TEL-AML1-C1	other	0.00991	0.99009	other
TEL-AML1-C20	other	0.00093	0.99907	other
TEL-AML1-C21 (testset)	other	0.0155	0.9845	other
TEL-AML1-C22 (testset)	other	0.00258	0.99742	other
TEL-AML1-C23	other	0.04501	0.95499	other
TEL-AML1-C24	other	0.00068	0.99932	other
TEL-AML1-C25	other	0.00605	0.99395	other
TEL-AML1-C26 (testset)	other	0.00161	0.99839	other
TEL-AML1-C27	other	0.00843	0.99157	other
TEL-AML1-C28 (testset)	other	0.00017	0.99983	other
TEL-AML1-C29	other	0.00038	0.99962	other
TEL-AML1-C2	other	0.00256	0.99744	other
TEL-AML1-C30 (testset)	other	0.00035	0.99965	other
TEL-AML1-C31 (testset)	other	0.00127	0.99873	other
TEL-AML1-C32	other	0.00043	0.99957	other
TEL-AML1-C33	other	0.0018	0.9982	other
TEL-AML1-C34 (testset)	other	0.00072	0.99928	other
TEL-AML1-C35 (testset)	other	0.00131	0.99869	other
TEL-AML1-C36	other	0.00282	0.99718	other
TEL-AML1-C37 (testset)	other	0.00097	0.99903	other
TEL-AML1-C38	other	0.00338	0.99662	other
TEL-AML1-C39	other	0.00836	0.99164	other
TEL-AML1-C3	other	0.0081	0.9919	other
TEL-AML1-C40 (testset)	other	0.0035	0.9965	other
TEL-AML1-C41	other	0.03359	0.96641	other
TEL-AML1-C42 (testset)	other	0.00141	0.99859	other
TEL-AML1-C43	other	0.00515	0.99485	other
TEL-AML1-C44	other	0.00826	0.99174	other
TEL-AML1-C45	other	0.09915	0.90085	other
TEL-AML1-C46 (testset)	other	0.02056	0.97944	other
TEL-AML1-C47	other	0.0059	0.9941	other
TEL-AML1-C48	other	0.00066	0.99934	other
TEL-AML1-C49 (testset)	other	0.01095	0.98905	other
TEL-AML1-C4 (testset)	other	0.00322	0.99678	other
TEL-AML1-C50 (testset)	other	0.00608	0.99392	other
TEL-AML1-C51	other	0.01217	0.98783	other
TEL-AML1-C52	other	0.01313	0.98687	other
TEL-AML1-C53 (testset)	other	0.02316	0.97684	other
TEL-AML1-C54 (testset)	other	5e-04	0.9995	other
TEL-AML1-C55	other	0.00682	0.99318	other
TEL-AML1-C56 (testset)	other	0.002	0.998	other
TEL-AML1-C57	other	0.00067	0.99933	other
TEL-AML1-C5	other	0.00701	0.99299	other
TEL-AML1-C6 (testset)	other	0.00241	0.99759	other
TEL-AML1-C7 (testset)	other	0.01499	0.98501	other
TEL-AML1-C8	other	0.05015	0.94985	other
TEL-AML1-C9	other	0.03182	0.96818	other
TEL-AML1-R1 (testset)	other	0.00233	0.99767	other
TEL-AML1-R2	other	0.00496	0.99504	other
TEL-AML1-R3	other	0.00337	0.99663	other