GO:0007254

GO:0007254

JNK cascade (annotated genes)

Biological Process

Parent node

GO:0007254	JNK cascade

This leaf node contains 29 genes

The following 18 of these are used in classification:

	Symbol	Genename	NORMAL score	SQUAMOUS score
1558_g_at	PAK1	p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)	-0.8411	0.6609
37543_at	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	0.7345	-0.5771
1557_at	PAK1	p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)	-0.6221	0.4888
1398_g_at	MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.453	-0.3559
1397_at	MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.381	-0.2993
35301_at	CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	-0.344	0.2703
36324_at	ADORA2B	adenosine A2b receptor	-0.3209	0.2522
40997_at	MAP3K12	mitogen-activated protein kinase kinase kinase 12	0.2872	-0.2257
35651_at	MAP3K4	mitogen-activated protein kinase kinase kinase 4	-0.2725	0.2141
40186_at	DUSP9	dual specificity phosphatase 9	-0.184	0.1446
415_at	CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	-0.1368	0.1075
35652_g_at	MAP3K4	mitogen-activated protein kinase kinase kinase 4	-0.1249	0.0981
520_at	MAP3K12	mitogen-activated protein kinase kinase kinase 12	0.1206	-0.0948
36910_at	MAP2K4	mitogen-activated protein kinase kinase 4	-0.1103	0.0867
1712_s_at	MAP2K4	mitogen-activated protein kinase kinase 4	-0.0822	0.0646
38555_at	DUSP10	dual specificity phosphatase 10	-0.0373	0.0293
1708_at	MAPK10	mitogen-activated protein kinase 10	-0.0104	0.0081
34006_s_at	MAPK8	mitogen-activated protein kinase 8	0.007	-0.0055

Performance on training data

• Error rate: 0
• Performance: 0.06463
• Redundancy: 4.09417

	Sensitivity	Specificity
NORMAL	1	1
SQUAMOUS	1	1

Performance on test data

• Error rate: 0
• Performance: 0.14984
• Redundancy: 3.64061

	Sensitivity	Specificity
NORMAL	1	1
SQUAMOUS	1	1

Predictions

	Class	NORMAL	SQUAMOUS	Predictionn
CL2001031606AA	SQUAMOUS	0.00315	0.99685	SQUAMOUS
CL2001031620AA (testset)	SQUAMOUS	0.27109	0.72891	SQUAMOUS
CL2001031621AA	SQUAMOUS	0.00056	0.99944	SQUAMOUS
CL2001032122AA	SQUAMOUS	0.00064	0.99936	SQUAMOUS
CL2001032129AA (testset)	SQUAMOUS	0.00068	0.99932	SQUAMOUS
CL2001032144AA	SQUAMOUS	0.00253	0.99747	SQUAMOUS
CL2001032153AA	SQUAMOUS	0.03089	0.96911	SQUAMOUS
CL2001032207AA (testset)	SQUAMOUS	0.00011	0.99989	SQUAMOUS
CL2001032209AA	SQUAMOUS	0.00011	0.99989	SQUAMOUS
CL2001032218AA (testset)	SQUAMOUS	0.00324	0.99676	SQUAMOUS
CL2001032222AA	SQUAMOUS	0.04018	0.95982	SQUAMOUS
CL2001032231AA (testset)	SQUAMOUS	0.39538	0.60462	SQUAMOUS
CL2001032239AA (testset)	SQUAMOUS	0.02293	0.97707	SQUAMOUS
CL2001032240AA	SQUAMOUS	0.01713	0.98287	SQUAMOUS
CL2001032305AA	SQUAMOUS	0.10633	0.89367	SQUAMOUS
CL2001032608AA	SQUAMOUS	0.00163	0.99837	SQUAMOUS
CL2001032627AA (testset)	SQUAMOUS	0.00036	0.99964	SQUAMOUS
CL2001032644AA	SQUAMOUS	2e-04	0.9998	SQUAMOUS
CL2001032719AA	SQUAMOUS	0.20637	0.79363	SQUAMOUS
CL2001032732AA	SQUAMOUS	0.22669	0.77331	SQUAMOUS
CL2001032853AA	SQUAMOUS	0.00292	0.99708	SQUAMOUS
CL2001032010AA (testset)	NORMAL	0.98768	0.01232	NORMAL
CL2001032041AA	NORMAL	0.98227	0.01773	NORMAL
CL2001032043AA	NORMAL	0.99518	0.00482	NORMAL
CL2001032045AA (testset)	NORMAL	0.96844	0.03156	NORMAL
CL2001032046AA	NORMAL	0.99777	0.00223	NORMAL
CL2001032102AA	NORMAL	0.99335	0.00665	NORMAL
CL2001032128AA (testset)	NORMAL	0.99527	0.00473	NORMAL
CL2001032147AA	NORMAL	0.99022	0.00978	NORMAL
CL2001032202AA (testset)	NORMAL	0.99368	0.00632	NORMAL
CL2001032206AA	NORMAL	0.99152	0.00848	NORMAL
CL2001032220AA	NORMAL	0.9976	0.0024	NORMAL
CL2001032256AA	NORMAL	0.98645	0.01355	NORMAL
CL2001032304AA	NORMAL	0.97649	0.02351	NORMAL
CL2001032718AA	NORMAL	0.9872	0.0128	NORMAL
CL2001032724AA (testset)	NORMAL	0.9882	0.0118	NORMAL
CL2001032725AA	NORMAL	0.99688	0.00312	NORMAL
CL2001032727AA (testset)	NORMAL	0.97018	0.02982	NORMAL