GO:0007166


GO:0007166

cell surface receptor linked signal transduction
(annotated genes)

Biological
Process

Parent node

This leaf node contains 170 genes

The following 85 of these are used in classification:

 SymbolGenenameSQUAMOUS scoreother score
1590_s_atHRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog0.7556-0.0872
32825_atHRMT1L2 HMT1 hnRNP methyltransferase-like 2 (S. cerevisiae)0.6742-0.0778
33563_s_atCOL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)-0.58720.0678
291_s_atTACSTD2 tumor-associated calcium signal transducer 20.5744-0.0663
37909_atLAMA3 laminin, alpha 30.5261-0.0607
40632_atGP1BB glycoprotein Ib (platelet), beta polypeptide-0.50190.0579
35701_atHRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog0.495-0.0571
33222_atFZD7 frizzled homolog 7 (Drosophila)0.4272-0.0493
815_atDOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)-0.38850.0448
40648_atMERTK c-mer proto-oncogene tyrosine kinase0.3096-0.0357
35842_atIL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor)-0.29930.0345
1786_atMERTK c-mer proto-oncogene tyrosine kinase0.2821-0.0326
35868_atAGER advanced glycosylation end product-specific receptor-0.27240.0314
33562_g_atCOL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)-0.25570.0295
37279_atGEM GTP binding protein overexpressed in skeletal muscle-0.25270.0292
684_atAGT angiotensinogen (serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8)-0.25180.0291
35316_atRRAGA Ras-related GTP binding A0.2435-0.0281
1085_s_atPLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)0.2414-0.0279
41354_atSTC1 stanniocalcin 10.236-0.0272
36162_atBSG basigin (OK blood group)0.236-0.0272
38398_atMADD MAP-kinase activating death domain-0.23420.027
514_atCBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b0.2153-0.0248
32043_atSTC2 stanniocalcin 20.2065-0.0238
37180_atPLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)0.206-0.0238
1534_atIL12RB2 interleukin 12 receptor, beta 20.2024-0.0233
36789_f_atLILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5-0.1980.0228
36252_atCTF1 cardiotrophin 1-0.19330.0223
31760_atSAG S-antigen; retina and pineal gland (arrestin)-0.19320.0223
38755_atFADD Fas (TNFRSF6)-associated via death domain0.1906-0.022
33561_atCOL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)-0.18480.0213
37621_atIL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor)-0.18040.0208
36879_atECGF1 endothelial cell growth factor 1 (platelet-derived)0.1793-0.0207
35632_atCBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b0.1685-0.0194
675_atIFITM1 interferon induced transmembrane protein 1 (9-27)0.1574-0.0182
1401_g_atCSF2 colony stimulating factor 2 (granulocyte-macrophage)-0.1450.0167
41169_atPLAUR plasminogen activator, urokinase receptor-0.1430.0165
32475_atLILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1-0.13910.016
35703_atPDGFA platelet-derived growth factor alpha polypeptide0.1305-0.0151
816_g_atDOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)-0.12250.0141
39665_atGLRB glycine receptor, beta-0.11540.0133
1665_s_atECGF1 endothelial cell growth factor 1 (platelet-derived)0.1154-0.0133
256_s_atLAMR1 laminin receptor 1 (ribosomal protein SA, 67kDa)0.1152-0.0133
1116_atCD19 CD19 antigen0.1132-0.0131
39424_atTNFRSF14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)-0.10170.0117
1648_atOSMR oncostatin M receptor-0.10120.0117
38177_atRAMP2 receptor (calcitonin) activity modifying protein 2-0.09790.0113
32750_r_atFLNA filamin A, alpha (actin binding protein 280)-0.09750.0113
32749_s_atFLNA filamin A, alpha (actin binding protein 280)0.0908-0.0105
35152_atRAMP3 receptor (calcitonin) activity modifying protein 3-0.08320.0096
1569_r_atIFNAR2 interferon (alpha, beta and omega) receptor 2-0.08240.0095
1988_atPDGFRA platelet-derived growth factor receptor, alpha polypeptide-0.0780.009
1609_g_atMET met proto-oncogene (hepatocyte growth factor receptor)-0.07720.0089
1437_atPRKCA protein kinase C, alpha-0.070.0081
189_s_atPLAUR plasminogen activator, urokinase receptor-0.06980.008
34153_atSAG S-antigen; retina and pineal gland (arrestin)-0.06880.0079
37645_atCD69 CD69 antigen (p60, early T-cell activation antigen)-0.06490.0075
31453_s_atLILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1-0.0610.007
31514_atDOK2 docking protein 2, 56kDa-0.06070.007
160032_atIL6R interleukin 6 receptor-0.0570.0066
34267_r_atLEPR leptin receptor-0.05610.0065
431_atCXCL10 chemokine (C-X-C motif) ligand 100.0499-0.0058
41189_atTNFRSF25 tumor necrosis factor receptor superfamily, member 250.0474-0.0055
40519_atPTPRC protein tyrosine phosphatase, receptor type, C-0.0470.0054
39277_atOSMR oncostatin M receptor-0.04640.0054
37843_i_atIL27RA interleukin 27 receptor, alpha-0.0430.005
33983_atIGSF2 immunoglobulin superfamily, member 2-0.0430.005
1745_atRET ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)-0.0420.0048
31916_atKLRA1 killer cell lectin-like receptor subfamily A, member 1-0.0420.0048
35661_g_atSAG S-antigen; retina and pineal gland (arrestin)-0.03910.0045
37844_atIL27RA interleukin 27 receptor, alpha-0.03450.004
1368_atIL1R1 interleukin 1 receptor, type I-0.03450.004
160038_s_atINS insulin-0.03020.0035
37799_atASGR2 asialoglycoprotein receptor 2-0.02960.0034
1731_atPDGFRA platelet-derived growth factor receptor, alpha polypeptide0.0284-0.0033
36578_atBIRC2 baculoviral IAP repeat-containing 20.0282-0.0033
1400_atCSF2 colony stimulating factor 2 (granulocyte-macrophage)-0.02750.0032
34433_atDOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)-0.02140.0025
515_s_atCBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b-0.02090.0024
1999_s_atMAPK14 mitogen-activated protein kinase 14-0.01970.0023
35684_atMET met proto-oncogene (hepatocyte growth factor receptor)-0.01550.0018
1157_s_atIFNAR1 interferon (alpha, beta and omega) receptor 10.0107-0.0012
1334_s_atCSF3 colony stimulating factor 3 (granulocyte)-0.00840.001
40566_atPRKCA protein kinase C, alpha-0.00486e-04
38517_atISGF3G interferon-stimulated transcription factor 3, gamma 48kDa0.0038-4e-04
35797_atIL13RA1 interleukin 13 receptor, alpha 1-0.00283e-04

Performance on training data

 SensitivitySpecificity
SQUAMOUS0.952380.98352
other0.983520.95238

Performance on test data

 SensitivitySpecificity
SQUAMOUS0.952380.98352
other0.983520.95238

Predictions

 ClassSQUAMOUSotherPredictionn
CL2001031606AA (testset)SQUAMOUS0.95260.0474 SQUAMOUS
CL2001031607AA (testset)other0.004520.99548 other
CL2001031608AA (testset)other0.000980.99902 other
CL2001031609AA (testset)other0.001610.99839 other
CL2001031611AA (testset)other0.367060.63294 other
CL2001031612AA (testset)other0.094570.90543 other
CL2001031613AA (testset)other0.277830.72217 other
CL2001031615AA (testset)other0.003990.99601 other
CL2001031616AA (testset)other0.221180.77882 other
CL2001031618AA (testset)other6e-050.99994 other
CL2001031620AA (testset)SQUAMOUS0.990110.00989 SQUAMOUS
CL2001031621AA (testset)SQUAMOUS0.974380.02562 SQUAMOUS
CL2001031622AA (testset)other0.478810.52119 other
CL2001031625AA (testset)other0.004240.99576 other
CL2001031627AA (testset)other0.001020.99898 other
CL2001031628AA (testset)other0.002140.99786 other
CL2001031629AA (testset)other0.435410.56459 other
CL2001031630AA (testset)other0.000580.99942 other
CL2001031631AA (testset)other0.028560.97144 other
CL2001031632AA (testset)other0.006950.99305 other
CL2001031634AA (testset)other0.000690.99931 other
CL2001031635AA (testset)other0.003330.99667 other
CL2001031636AA (testset)other0.026970.97303 other
CL2001032002AA (testset)other0.000260.99974 other
CL2001032005AA (testset)other0.01020.9898 other
CL2001032008AA (testset)other0.450190.54981 other
CL2001032009AA (testset)other0.001690.99831 other
CL2001032010AA (testset)other0.000350.99965 other
CL2001032011AA (testset)other0.009790.99021 other
CL2001032012AA (testset)other0.002020.99798 other
CL2001032013AA (testset)other0.001480.99852 other
CL2001032015AA (testset)other0.015990.98401 other
CL2001032016AA (testset)other0.018340.98166 other
CL2001032019AA (testset)other0.004370.99563 other
CL2001032020AA (testset)other0.003110.99689 other
CL2001032025AA (testset)other0.000540.99946 other
CL2001032026AA (testset)other9e-040.9991 other
CL2001032027AA (testset)other0.12140.8786 other
CL2001032030AA (testset)other0.251940.74806 other
CL2001032031AA (testset)other0.012210.98779 other
CL2001032032AA (testset)other0.000360.99964 other
CL2001032034AA (testset)other0.014760.98524 other
CL2001032036AA (testset)other0.019440.98056 other
CL2001032041AA (testset)other0.006910.99309 other
CL2001032043AA (testset)other0.019420.98058 other
CL2001032044AA (testset)other0.000460.99954 other
CL2001032045AA (testset)other0.000490.99951 other
CL2001032046AA (testset)other0.004350.99565 other
CL2001032101AA (testset)other0.001220.99878 other
CL2001032102AA (testset)other0.001040.99896 other
CL2001032103AA (testset)other0.001750.99825 other
CL2001032104AA (testset)other0.001650.99835 other
CL2001032105AA (testset)other0.001690.99831 other
CL2001032107AA (testset)other0.007730.99227 other
CL2001032108AA (testset)other0.000240.99976 other
CL2001032109AA (testset)other0.000630.99937 other
CL2001032110AA (testset)other0.001370.99863 other
CL2001032111AA (testset)other0.001410.99859 other
CL2001032113AA (testset)other0.000280.99972 other
CL2001032114AA (testset)other0.004580.99542 other
CL2001032115AA (testset)other2e-050.99998 other
CL2001032116AA (testset)other0.001360.99864 other
CL2001032117AA (testset)other0.03890.9611 other
CL2001032121AA (testset)other0.021050.97895 other
CL2001032122AA (testset)SQUAMOUS0.899660.10034 SQUAMOUS
CL2001032124AA (testset)other0.003410.99659 other
CL2001032125AA (testset)other0.041930.95807 other
CL2001032127AA (testset)other0.004630.99537 other
CL2001032128AA (testset)other0.035750.96425 other
CL2001032129AA (testset)SQUAMOUS0.973450.02655 SQUAMOUS
CL2001032130AA (testset)other0.029660.97034 other
CL2001032132AA (testset)other0.003010.99699 other
CL2001032134AA (testset)other0.082210.91779 other
CL2001032135AA (testset)other0.034870.96513 other
CL2001032136AA (testset)other0.056830.94317 other
CL2001032138AA (testset)other0.005480.99452 other
CL2001032141AA (testset)other0.022640.97736 other
CL2001032142AA (testset)other0.05560.9444 other
CL2001032144AA (testset)SQUAMOUS0.997110.00289 SQUAMOUS
CL2001032145AA (testset)other8e-040.9992 other
CL2001032147AA (testset)other0.003120.99688 other
CL2001032149AA (testset)other0.157260.84274 other
CL2001032151AA (testset)other0.000690.99931 other
CL2001032152AA (testset)other0.000410.99959 other
CL2001032153AA (testset)SQUAMOUS0.503660.49634 SQUAMOUS
CL2001032155AA (testset)other0.221840.77816 other
CL2001032156AA (testset)other0.058860.94114 other
CL2001032202AA (testset)other0.009430.99057 other
CL2001032206AA (testset)other0.005850.99415 other
CL2001032207AA (testset)SQUAMOUS0.557140.44286 SQUAMOUS
CL2001032209AA (testset)SQUAMOUS0.998820.00118 SQUAMOUS
CL2001032210AA (testset)other0.003290.99671 other
CL2001032211AA (testset)other0.0040.996 other
CL2001032212AA (testset)other0.006450.99355 other
CL2001032213AA (testset)other0.04530.9547 other
CL2001032214AA (testset)other0.045870.95413 other
CL2001032217AA (testset)other0.020990.97901 other
CL2001032218AA (testset)SQUAMOUS0.947220.05278 SQUAMOUS
CL2001032219AA (testset)other0.003020.99698 other
CL2001032220AA (testset)other0.001020.99898 other
CL2001032222AA (testset)SQUAMOUS0.987040.01296 SQUAMOUS
CL2001032229AA (testset)other0.00180.9982 other
CL2001032231AA (testset)SQUAMOUS0.679650.32035 SQUAMOUS
CL2001032232AA (testset)other0.000630.99937 other
CL2001032233AA (testset)other0.002120.99788 other
CL2001032238AA (testset)other0.000590.99941 other
CL2001032239AA (testset)SQUAMOUS0.92110.0789 SQUAMOUS
CL2001032240AA (testset)SQUAMOUS0.980060.01994 SQUAMOUS
CL2001032241AA (testset)other0.003240.99676 other
CL2001032242AA (testset)other0.060080.93992 other
CL2001032243AA (testset)other0.000420.99958 other
CL2001032248AA (testset)other0.528320.47168 SQUAMOUS
CL2001032249AA (testset)other0.002110.99789 other
CL2001032252AA (testset)other0.309090.69091 other
CL2001032254AA (testset)other0.001790.99821 other
CL2001032255AA (testset)other0.113130.88687 other
CL2001032256AA (testset)other0.000890.99911 other
CL2001032259AA (testset)other0.001560.99844 other
CL2001032260AA (testset)other0.014830.98517 other
CL2001032301AA (testset)other0.060220.93978 other
CL2001032304AA (testset)other0.046320.95368 other
CL2001032305AA (testset)SQUAMOUS0.737430.26257 SQUAMOUS
CL2001032306AA (testset)other0.015290.98471 other
CL2001032307AA (testset)other0.01270.9873 other
CL2001032308AA (testset)other0.024540.97546 other
CL2001032309AA (testset)other0.000250.99975 other
CL2001032310AA (testset)other0.000390.99961 other
CL2001032311AA (testset)other0.87470.1253 SQUAMOUS
CL2001032312AA (testset)other0.000290.99971 other
CL2001032313AA (testset)other0.004850.99515 other
CL2001032314AA (testset)other0.000770.99923 other
CL2001032316AA (testset)other0.001070.99893 other
CL2001032601AA (testset)other0.025150.97485 other
CL2001032602AA (testset)other0.004910.99509 other
CL2001032604AA (testset)other0.002990.99701 other
CL2001032607AA (testset)other0.001260.99874 other
CL2001032608AA (testset)SQUAMOUS0.967230.03277 SQUAMOUS
CL2001032610AA (testset)other0.013590.98641 other
CL2001032612AA (testset)other0.000390.99961 other
CL2001032613AA (testset)other0.003120.99688 other
CL2001032614AA (testset)other0.003120.99688 other
CL2001032616AA (testset)other0.000910.99909 other
CL2001032617AA (testset)other0.050570.94943 other
CL2001032620AA (testset)other0.000740.99926 other
CL2001032625AA (testset)other0.000220.99978 other
CL2001032627AA (testset)SQUAMOUS0.997650.00235 SQUAMOUS
CL2001032628AA (testset)other0.001020.99898 other
CL2001032629AA (testset)other0.000150.99985 other
CL2001032630AA (testset)other0.002590.99741 other
CL2001032632AA (testset)other0.015830.98417 other
CL2001032638AA (testset)other0.029010.97099 other
CL2001032640AA (testset)other0.003660.99634 other
CL2001032643AA (testset)other0.160880.83912 other
CL2001032644AA (testset)SQUAMOUS0.94640.0536 SQUAMOUS
CL2001032647AA (testset)other0.002950.99705 other
CL2001032701AA (testset)other0.002630.99737 other
CL2001032702AA (testset)other0.028220.97178 other
CL2001032703AA (testset)other0.030990.96901 other
CL2001032704AA (testset)other0.046520.95348 other
CL2001032706AA (testset)other0.002940.99706 other
CL2001032709AA (testset)other0.0870.913 other
CL2001032716AA (testset)other0.218840.78116 other
CL2001032717AA (testset)other0.000370.99963 other
CL2001032718AA (testset)other0.017890.98211 other
CL2001032719AA (testset)SQUAMOUS0.980280.01972 SQUAMOUS
CL2001032720AA (testset)other0.000780.99922 other
CL2001032722AA (testset)other0.005780.99422 other
CL2001032724AA (testset)other0.000420.99958 other
CL2001032725AA (testset)other0.001870.99813 other
CL2001032727AA (testset)other0.001580.99842 other
CL2001032729AA (testset)other0.032180.96782 other
CL2001032730AA (testset)other0.034780.96522 other
CL2001032732AA (testset)SQUAMOUS0.210180.78982 other
CL2001032733AA (testset)other0.000820.99918 other
CL2001032738AA (testset)other0.093580.90642 other
CL2001032742AA (testset)other0.510220.48978 SQUAMOUS
CL2001032746AA (testset)other0.142460.85754 other
CL2001032747AA (testset)other0.004520.99548 other
CL2001032833AA (testset)other0.008310.99169 other
CL2001032836AA (testset)other0.387690.61231 other
CL2001032838AA (testset)other0.062040.93796 other
CL2001032839AA (testset)other0.024870.97513 other
CL2001032841AA (testset)other4e-050.99996 other
CL2001032842AA (testset)other0.056170.94383 other
CL2001032843AA (testset)other0.011350.98865 other
CL2001032845AA (testset)other0.000520.99948 other
CL2001032846AA (testset)other0.000680.99932 other
CL2001032847AA (testset)other0.000810.99919 other
CL2001032848AA (testset)other0.012120.98788 other
CL2001032850AA (testset)other0.000390.99961 other
CL2001032853AA (testset)SQUAMOUS0.899920.10008 SQUAMOUS
CL2001032854AA (testset)other0.000480.99952 other
CL2001032856AA (testset)other0.010530.98947 other
CL2001032857AA (testset)other6e-040.9994 other
CL2001032860AA (testset)other0.005760.99424 other
CL2001040305AA (testset)other0.002330.99767 other
CL2001040306AA (testset)other7e-040.9993 other
CL2001041708AA (testset)other0.000710.99929 other
CL2001041711AA (testset)other0.000190.99981 other
CL2001041716AA (testset)other0.013170.98683 other
CL2001042501AA (testset)other8e-050.99992 other
CL2001042505AA (testset)other0.00540.9946 other
CL2001042506AA (testset)other0.01260.9874 other

 


Generated by StAM on Tue Sep 7 18:15:25 2004