GO:0006629

GO:0006629

lipid metabolism (annotated genes)

Biological Process

Parent node

GO:0006629	lipid metabolism

This leaf node contains 96 genes

The following 55 of these are used in classification:

	Symbol	Genename	SQUAMOUS score	other score
39799_at	FABP5	fatty acid binding protein 5 (psoriasis-associated)	0.8274	-0.0957
37956_at	ALDH3B2	aldehyde dehydrogenase 3 family, member B2	0.7587	-0.0878
40685_at	ALDH3B1	aldehyde dehydrogenase 3 family, member B1	-0.5664	0.0655
35454_at	KIAA0450	KIAA0450 gene product	0.4967	-0.0575
40372_at	PNLIPRP1	pancreatic lipase-related protein 1	-0.3655	0.0423
34790_at	ACAT2	acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase)	0.3414	-0.0395
35009_at	LRP2	low density lipoprotein-related protein 2	-0.3222	0.0373
40081_at	PLTP	phospholipid transfer protein	0.319	-0.0369
31645_at	BTNL3	butyrophilin-like 3	-0.3125	0.0362
37945_at	BACH	brain acyl-CoA hydrolase	0.3088	-0.0357
34422_r_at	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	-0.2926	0.0339
33634_at	ATP8B1	ATPase, Class I, type 8B, member 1	0.2893	-0.0335
40703_at	RBP3	retinol binding protein 3, interstitial	-0.2745	0.0318
39062_at	PTE1	peroxisomal acyl-CoA thioesterase	-0.2579	0.0298
32398_s_at	LRP8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	0.2422	-0.028
37399_at	AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.2295	-0.0266
32135_at	SREBF1	sterol regulatory element binding transcription factor 1	0.2273	-0.0263
32630_f_at	BTN3A1	butyrophilin, subfamily 3, member A1	-0.2104	0.0243
36964_at	MBTPS1	membrane-bound transcription factor protease, site 1	-0.2061	0.0238
40330_at	PLCE1	phospholipase C, epsilon 1	-0.2044	0.0236
40452_at	CPNE1	copine I	0.1988	-0.023
37104_at	PPARG	peroxisome proliferative activated receptor, gamma	-0.1954	0.0226
38313_at	ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2	-0.1902	0.022
35511_at	C11orf11	chromosome 11 open reading frame 11	-0.1739	0.0201
35875_at	SGPL1	sphingosine-1-phosphate lyase 1	-0.1739	0.0201
41764_at	APOC1	apolipoprotein C-I	-0.1666	0.0193
36681_at	APOD	apolipoprotein D	-0.1576	0.0182
34517_at	HMGCS1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)	0.1567	-0.0181
41796_at	PLCL2	phospholipase C-like 2	-0.1495	0.0173
41227_at	OCRL	oculocerebrorenal syndrome of Lowe	-0.1444	0.0167
1755_i_at	CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.1305	-0.0151
35296_at	GGPS1	geranylgeranyl diphosphate synthase 1	0.1304	-0.0151
918_at	ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2	-0.1217	0.0141
40012_at	LRP8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	0.1148	-0.0133
41831_at	LRP5	low density lipoprotein receptor-related protein 5	-0.113	0.0131
36686_at	ALDH1A3	aldehyde dehydrogenase 1 family, member A3	0.1088	-0.0126
35099_at	APOL1	apolipoprotein L, 1	0.0956	-0.0111
40778_at	HADH2	hydroxyacyl-Coenzyme A dehydrogenase, type II	0.0894	-0.0103
36533_at	PTGIS	prostaglandin I2 (prostacyclin) synthase	-0.088	0.0102
39018_at	MGST3	microsomal glutathione S-transferase 3	-0.0873	0.0101
34523_at	APOA4	apolipoprotein A-IV	-0.0759	0.0088
36779_at	FABP6	fatty acid binding protein 6, ileal (gastrotropin)	-0.0718	0.0083
759_at	PTGIS	prostaglandin I2 (prostacyclin) synthase	-0.0715	0.0083
39706_at	CPNE3	copine III	0.0683	-0.0079
38909_at	CYP27B1	cytochrome P450, family 27, subfamily B, polypeptide 1	-0.0594	0.0069
32855_at	LDLR	low density lipoprotein receptor (familial hypercholesterolemia)	0.0574	-0.0066
40295_at	CPNE6	copine VI (neuronal)	0.044	-0.0051
160038_s_at	INS	insulin	-0.0424	0.0049
364_s_at	PLCB3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.0409	-0.0047
34420_at	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	-0.0294	0.0034
39328_at	HMGCR	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	-0.0274	0.0032
32363_at	CH25H	cholesterol 25-hydroxylase	-0.0191	0.0022
33022_at	RODH-4	microsomal NAD+-dependent retinol dehydrogenase 4	-0.0049	6e-04
41377_f_at	UGT2B7	UDP glycosyltransferase 2 family, polypeptide B7	-0.0033	4e-04
36841_at	PTE1	peroxisomal acyl-CoA thioesterase	-0.0011	1e-04

Performance on training data

• Error rate: 0.02222
• Performance: 0.13649
• Redundancy: 3.51458

	Sensitivity	Specificity
SQUAMOUS	0.78571	1
other	1	0.78571

Performance on test data

• Error rate: 0.02941
• Performance: 0.12097
• Redundancy: 3.79015

	Sensitivity	Specificity
SQUAMOUS	0.71429	1
other	1	0.71429

Predictions

	Class	SQUAMOUS	other	Predictionn
CL2001031606AA (testset)	SQUAMOUS	0.92055	0.07945	SQUAMOUS
CL2001031607AA	other	0.01888	0.98112	other
CL2001031608AA	other	0.00953	0.99047	other
CL2001031609AA (testset)	other	0.00783	0.99217	other
CL2001031611AA	other	0.04079	0.95921	other
CL2001031612AA (testset)	other	0.07327	0.92673	other
CL2001031613AA (testset)	other	0.00375	0.99625	other
CL2001031615AA (testset)	other	0.00375	0.99625	other
CL2001031616AA	other	0.05643	0.94357	other
CL2001031618AA	other	0.00228	0.99772	other
CL2001031620AA	SQUAMOUS	0.25012	0.74988	other
CL2001031621AA	SQUAMOUS	0.96628	0.03372	SQUAMOUS
CL2001031622AA	other	0.14088	0.85912	other
CL2001031625AA	other	0.00075	0.99925	other
CL2001031627AA (testset)	other	0.00366	0.99634	other
CL2001031628AA	other	0.00135	0.99865	other
CL2001031629AA	other	0.09408	0.90592	other
CL2001031630AA	other	0.00019	0.99981	other
CL2001031631AA (testset)	other	0.00438	0.99562	other
CL2001031632AA	other	0.01831	0.98169	other
CL2001031634AA	other	0.00426	0.99574	other
CL2001031635AA (testset)	other	0.00127	0.99873	other
CL2001031636AA (testset)	other	0.0362	0.9638	other
CL2001032002AA	other	0.00062	0.99938	other
CL2001032005AA	other	0.01795	0.98205	other
CL2001032008AA	other	0.05026	0.94974	other
CL2001032009AA	other	0.02074	0.97926	other
CL2001032010AA	other	0.00072	0.99928	other
CL2001032011AA	other	0.02609	0.97391	other
CL2001032012AA	other	0.00634	0.99366	other
CL2001032013AA	other	0.00196	0.99804	other
CL2001032015AA (testset)	other	0.00714	0.99286	other
CL2001032016AA (testset)	other	2e-04	0.9998	other
CL2001032019AA	other	0.00548	0.99452	other
CL2001032020AA (testset)	other	0.00186	0.99814	other
CL2001032025AA (testset)	other	0.00388	0.99612	other
CL2001032026AA	other	0.01031	0.98969	other
CL2001032027AA (testset)	other	0.01447	0.98553	other
CL2001032030AA (testset)	other	0.01673	0.98327	other
CL2001032031AA (testset)	other	0.04781	0.95219	other
CL2001032032AA	other	0.01238	0.98762	other
CL2001032034AA (testset)	other	0.14543	0.85457	other
CL2001032036AA	other	0.02166	0.97834	other
CL2001032041AA (testset)	other	0.02505	0.97495	other
CL2001032043AA	other	0.00342	0.99658	other
CL2001032044AA	other	0.0025	0.9975	other
CL2001032045AA (testset)	other	0.00765	0.99235	other
CL2001032046AA	other	0.00745	0.99255	other
CL2001032101AA	other	0.002	0.998	other
CL2001032102AA	other	0.00211	0.99789	other
CL2001032103AA	other	0.00289	0.99711	other
CL2001032104AA	other	0.00062	0.99938	other
CL2001032105AA	other	0.01543	0.98457	other
CL2001032107AA	other	0.00723	0.99277	other
CL2001032108AA (testset)	other	0.00323	0.99677	other
CL2001032109AA (testset)	other	0.01499	0.98501	other
CL2001032110AA	other	0.01163	0.98837	other
CL2001032111AA (testset)	other	0.00286	0.99714	other
CL2001032113AA	other	0.00261	0.99739	other
CL2001032114AA	other	0.00366	0.99634	other
CL2001032115AA	other	0.00309	0.99691	other
CL2001032116AA	other	0.00104	0.99896	other
CL2001032117AA (testset)	other	0.02221	0.97779	other
CL2001032121AA	other	0.00676	0.99324	other
CL2001032122AA	SQUAMOUS	0.97583	0.02417	SQUAMOUS
CL2001032124AA (testset)	other	0.0035	0.9965	other
CL2001032125AA	other	0.00284	0.99716	other
CL2001032127AA (testset)	other	0.0026	0.9974	other
CL2001032128AA (testset)	other	0.02153	0.97847	other
CL2001032129AA (testset)	SQUAMOUS	0.9231	0.0769	SQUAMOUS
CL2001032130AA	other	0.00502	0.99498	other
CL2001032132AA (testset)	other	0.00105	0.99895	other
CL2001032134AA	other	0.09527	0.90473	other
CL2001032135AA	other	0.02001	0.97999	other
CL2001032136AA (testset)	other	0.02723	0.97277	other
CL2001032138AA	other	0.00383	0.99617	other
CL2001032141AA	other	0.00606	0.99394	other
CL2001032142AA	other	0.06627	0.93373	other
CL2001032144AA	SQUAMOUS	0.9986	0.0014	SQUAMOUS
CL2001032145AA (testset)	other	0.00762	0.99238	other
CL2001032147AA (testset)	other	0.00998	0.99002	other
CL2001032149AA (testset)	other	0.041	0.959	other
CL2001032151AA (testset)	other	0.02572	0.97428	other
CL2001032152AA	other	0.00197	0.99803	other
CL2001032153AA (testset)	SQUAMOUS	0.17779	0.82221	other
CL2001032155AA	other	0.30635	0.69365	other
CL2001032156AA	other	0.06238	0.93762	other
CL2001032202AA	other	0.0064	0.9936	other
CL2001032206AA (testset)	other	0.01414	0.98586	other
CL2001032207AA	SQUAMOUS	0.80092	0.19908	SQUAMOUS
CL2001032209AA (testset)	SQUAMOUS	0.83128	0.16872	SQUAMOUS
CL2001032210AA	other	0.03981	0.96019	other
CL2001032211AA (testset)	other	0.0107	0.9893	other
CL2001032212AA (testset)	other	0.00673	0.99327	other
CL2001032213AA	other	0.02786	0.97214	other
CL2001032214AA	other	0.04176	0.95824	other
CL2001032217AA (testset)	other	0.033	0.967	other
CL2001032218AA	SQUAMOUS	0.83497	0.16503	SQUAMOUS
CL2001032219AA	other	0.07348	0.92652	other
CL2001032220AA	other	0.00127	0.99873	other
CL2001032222AA	SQUAMOUS	0.96587	0.03413	SQUAMOUS
CL2001032229AA	other	0.01029	0.98971	other
CL2001032231AA	SQUAMOUS	0.79442	0.20558	SQUAMOUS
CL2001032232AA (testset)	other	0.00243	0.99757	other
CL2001032233AA	other	0.0025	0.9975	other
CL2001032238AA (testset)	other	0.00228	0.99772	other
CL2001032239AA	SQUAMOUS	0.40416	0.59584	other
CL2001032240AA	SQUAMOUS	0.77573	0.22427	SQUAMOUS
CL2001032241AA	other	0.00348	0.99652	other
CL2001032242AA	other	0.00131	0.99869	other
CL2001032243AA (testset)	other	0.00065	0.99935	other
CL2001032248AA	other	0.03528	0.96472	other
CL2001032249AA	other	0.00077	0.99923	other
CL2001032252AA	other	0.22369	0.77631	other
CL2001032254AA (testset)	other	0.00195	0.99805	other
CL2001032255AA (testset)	other	0.00574	0.99426	other
CL2001032256AA	other	0.00609	0.99391	other
CL2001032259AA (testset)	other	0.00275	0.99725	other
CL2001032260AA (testset)	other	0.00806	0.99194	other
CL2001032301AA	other	0.13211	0.86789	other
CL2001032304AA	other	0.0231	0.9769	other
CL2001032305AA (testset)	SQUAMOUS	0.48521	0.51479	other
CL2001032306AA	other	0.09825	0.90175	other
CL2001032307AA	other	0.02727	0.97273	other
CL2001032308AA	other	0.11271	0.88729	other
CL2001032309AA	other	0.00216	0.99784	other
CL2001032310AA	other	0.00073	0.99927	other
CL2001032311AA	other	0.06978	0.93022	other
CL2001032312AA	other	0.00618	0.99382	other
CL2001032313AA	other	0.001	0.999	other
CL2001032314AA	other	0.01265	0.98735	other
CL2001032316AA	other	0.00225	0.99775	other
CL2001032601AA	other	0.01472	0.98528	other
CL2001032602AA (testset)	other	0.00351	0.99649	other
CL2001032604AA (testset)	other	0.00271	0.99729	other
CL2001032607AA (testset)	other	0.06794	0.93206	other
CL2001032608AA	SQUAMOUS	0.94783	0.05217	SQUAMOUS
CL2001032610AA	other	0.07849	0.92151	other
CL2001032612AA	other	0.00924	0.99076	other
CL2001032613AA	other	0.01521	0.98479	other
CL2001032614AA (testset)	other	0.00489	0.99511	other
CL2001032616AA	other	0.00661	0.99339	other
CL2001032617AA	other	0.0107	0.9893	other
CL2001032620AA	other	0.00213	0.99787	other
CL2001032625AA	other	0.00468	0.99532	other
CL2001032627AA	SQUAMOUS	0.9863	0.0137	SQUAMOUS
CL2001032628AA	other	0.00626	0.99374	other
CL2001032629AA (testset)	other	0.0106	0.9894	other
CL2001032630AA (testset)	other	0.00487	0.99513	other
CL2001032632AA	other	0.03143	0.96857	other
CL2001032638AA	other	0.00849	0.99151	other
CL2001032640AA	other	0.00241	0.99759	other
CL2001032643AA	other	0.0361	0.9639	other
CL2001032644AA (testset)	SQUAMOUS	0.77611	0.22389	SQUAMOUS
CL2001032647AA	other	0.00795	0.99205	other
CL2001032701AA	other	0.00921	0.99079	other
CL2001032702AA	other	0.01745	0.98255	other
CL2001032703AA	other	0.05571	0.94429	other
CL2001032704AA	other	0.02034	0.97966	other
CL2001032706AA	other	0.00813	0.99187	other
CL2001032709AA (testset)	other	0.00884	0.99116	other
CL2001032716AA	other	0.08163	0.91837	other
CL2001032717AA (testset)	other	0.00394	0.99606	other
CL2001032718AA	other	0.0032	0.9968	other
CL2001032719AA (testset)	SQUAMOUS	0.96594	0.03406	SQUAMOUS
CL2001032720AA	other	0.19416	0.80584	other
CL2001032722AA	other	0.00169	0.99831	other
CL2001032724AA	other	0.0197	0.9803	other
CL2001032725AA (testset)	other	0.00436	0.99564	other
CL2001032727AA	other	0.00945	0.99055	other
CL2001032729AA	other	0.00495	0.99505	other
CL2001032730AA	other	0.0262	0.9738	other
CL2001032732AA	SQUAMOUS	0.1339	0.8661	other
CL2001032733AA (testset)	other	0.0106	0.9894	other
CL2001032738AA	other	0.08197	0.91803	other
CL2001032742AA (testset)	other	0.07628	0.92372	other
CL2001032746AA (testset)	other	0.01053	0.98947	other
CL2001032747AA (testset)	other	0.02954	0.97046	other
CL2001032833AA (testset)	other	0.01982	0.98018	other
CL2001032836AA	other	0.28914	0.71086	other
CL2001032838AA	other	0.01322	0.98678	other
CL2001032839AA	other	0.02148	0.97852	other
CL2001032841AA	other	0.00036	0.99964	other
CL2001032842AA	other	0.0299	0.9701	other
CL2001032843AA	other	0.00223	0.99777	other
CL2001032845AA (testset)	other	0.00243	0.99757	other
CL2001032846AA (testset)	other	0.00225	0.99775	other
CL2001032847AA (testset)	other	0.00533	0.99467	other
CL2001032848AA	other	0.06059	0.93941	other
CL2001032850AA	other	0.0015	0.9985	other
CL2001032853AA	SQUAMOUS	0.90898	0.09102	SQUAMOUS
CL2001032854AA	other	0.01314	0.98686	other
CL2001032856AA	other	0.00705	0.99295	other
CL2001032857AA	other	0.00599	0.99401	other
CL2001032860AA	other	0.04776	0.95224	other
CL2001040305AA	other	0.01095	0.98905	other
CL2001040306AA	other	0.00571	0.99429	other
CL2001041708AA (testset)	other	0.0068	0.9932	other
CL2001041711AA	other	0.02675	0.97325	other
CL2001041716AA	other	0.00701	0.99299	other
CL2001042501AA	other	0.01358	0.98642	other
CL2001042505AA (testset)	other	0.02652	0.97348	other
CL2001042506AA	other	0.03122	0.96878	other