GO:0007229

GO:0007229

integrin-mediated signaling pathway (annotated genes)

Biological Process

Parent node

GO:0007166	cell surface receptor linked signal transduction

This leaf node contains 53 genes

The following 13 of these are used in classification:

	Symbol	Genename	NORMAL score	other score
32780_at	BPAG1	bullous pemphigoid antigen 1, 230/240kDa	0.8591	-0.0762
41005_at	ITGA8	integrin, alpha 8	0.6818	-0.0605
36709_at	ITGAX	integrin, alpha X (antigen CD11C (p150), alpha polypeptide)	0.5782	-0.0513
35365_at	ILK	integrin-linked kinase	0.4496	-0.0399
39753_at	ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.4056	-0.036
38547_at	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.3785	-0.0336
120_at	ITGA1	integrin, alpha 1	0.2487	-0.0221
37918_at	ITGB2	integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)	0.238	-0.0211
37574_at	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.2036	-0.0181
36892_at	ITGA7	integrin, alpha 7	0.2034	-0.018
37484_at	ITGA1	integrin, alpha 1	0.1021	-0.0091
406_at	ITGB4	integrin, beta 4	-0.0731	0.0065
38533_s_at	ITGAM	integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide)	0.0145	-0.0013

Performance on training data

• Error rate: 0.02222
• Performance: 0.18467
• Redundancy: 3.07116

	Sensitivity	Specificity
NORMAL	0.90909	0.98387
other	0.98387	0.90909

Performance on test data

• Error rate: 0.02941
• Performance: 0.17349
• Redundancy: 2.95317

	Sensitivity	Specificity
NORMAL	0.66667	1
other	1	0.66667

Predictions

	Class	NORMAL	other	Predictionn
CL2001031606AA	other	0.00173	0.99827	other
CL2001031607AA	other	0.05164	0.94836	other
CL2001031608AA	other	0.38524	0.61476	other
CL2001031609AA	other	0.01341	0.98659	other
CL2001031611AA	other	0.02619	0.97381	other
CL2001031612AA	other	0.03209	0.96791	other
CL2001031613AA	other	0.50421	0.49579	NORMAL
CL2001031615AA	other	0.02503	0.97497	other
CL2001031616AA (testset)	other	0.13615	0.86385	other
CL2001031618AA	other	0.0187	0.9813	other
CL2001031620AA (testset)	other	0.00402	0.99598	other
CL2001031621AA (testset)	other	0.02778	0.97222	other
CL2001031622AA	other	0.01376	0.98624	other
CL2001031625AA	other	0.01251	0.98749	other
CL2001031627AA (testset)	other	0.03188	0.96812	other
CL2001031628AA (testset)	other	0.04755	0.95245	other
CL2001031629AA	other	0.00921	0.99079	other
CL2001031630AA (testset)	other	0.00231	0.99769	other
CL2001031631AA	other	0.02347	0.97653	other
CL2001031632AA	other	0.01878	0.98122	other
CL2001031634AA	other	0.1076	0.8924	other
CL2001031635AA	other	0.09647	0.90353	other
CL2001031636AA	other	0.22738	0.77262	other
CL2001032002AA	other	0.00284	0.99716	other
CL2001032005AA	other	0.00888	0.99112	other
CL2001032008AA	other	0.0261	0.9739	other
CL2001032009AA (testset)	other	0.00186	0.99814	other
CL2001032010AA (testset)	NORMAL	0.74572	0.25428	NORMAL
CL2001032011AA (testset)	other	0.07343	0.92657	other
CL2001032012AA (testset)	other	0.0489	0.9511	other
CL2001032013AA (testset)	other	0.17863	0.82137	other
CL2001032015AA	other	0.43671	0.56329	other
CL2001032016AA (testset)	other	0.03617	0.96383	other
CL2001032019AA	other	0.07817	0.92183	other
CL2001032020AA (testset)	other	0.07867	0.92133	other
CL2001032025AA	other	0.0119	0.9881	other
CL2001032026AA	other	0.01054	0.98946	other
CL2001032027AA	other	0.0494	0.9506	other
CL2001032030AA	other	0.00629	0.99371	other
CL2001032031AA (testset)	other	0.01799	0.98201	other
CL2001032032AA	other	0.01705	0.98295	other
CL2001032034AA	other	0.18541	0.81459	other
CL2001032036AA	other	0.03032	0.96968	other
CL2001032041AA	NORMAL	0.79022	0.20978	NORMAL
CL2001032043AA	NORMAL	0.79325	0.20675	NORMAL
CL2001032044AA	other	0.00772	0.99228	other
CL2001032045AA (testset)	NORMAL	0.45179	0.54821	other
CL2001032046AA	NORMAL	0.52866	0.47134	NORMAL
CL2001032101AA	other	0.17147	0.82853	other
CL2001032102AA	NORMAL	0.80238	0.19762	NORMAL
CL2001032103AA	other	0.02894	0.97106	other
CL2001032104AA	other	0.00454	0.99546	other
CL2001032105AA	other	0.00603	0.99397	other
CL2001032107AA	other	0.00728	0.99272	other
CL2001032108AA	other	0.03936	0.96064	other
CL2001032109AA (testset)	other	0.01022	0.98978	other
CL2001032110AA	other	0.2047	0.7953	other
CL2001032111AA	other	0.03498	0.96502	other
CL2001032113AA (testset)	other	0.00353	0.99647	other
CL2001032114AA	other	0.2331	0.7669	other
CL2001032115AA (testset)	other	0.00745	0.99255	other
CL2001032116AA (testset)	other	0.0112	0.9888	other
CL2001032117AA	other	0.01754	0.98246	other
CL2001032121AA	other	0.00959	0.99041	other
CL2001032122AA	other	0.01657	0.98343	other
CL2001032124AA	other	0.01696	0.98304	other
CL2001032125AA	other	0.00072	0.99928	other
CL2001032127AA (testset)	other	0.01572	0.98428	other
CL2001032128AA (testset)	NORMAL	0.70133	0.29867	NORMAL
CL2001032129AA (testset)	other	0.0391	0.9609	other
CL2001032130AA	other	0.03457	0.96543	other
CL2001032132AA	other	0.0162	0.9838	other
CL2001032134AA (testset)	other	0.05947	0.94053	other
CL2001032135AA	other	0.03277	0.96723	other
CL2001032136AA (testset)	other	0.05009	0.94991	other
CL2001032138AA (testset)	other	0.1531	0.8469	other
CL2001032141AA (testset)	other	0.02429	0.97571	other
CL2001032142AA	other	0.02677	0.97323	other
CL2001032144AA	other	0.00458	0.99542	other
CL2001032145AA	other	0.00439	0.99561	other
CL2001032147AA	NORMAL	0.94202	0.05798	NORMAL
CL2001032149AA (testset)	other	0.08261	0.91739	other
CL2001032151AA	other	0.00518	0.99482	other
CL2001032152AA	other	0.00311	0.99689	other
CL2001032153AA	other	0.02875	0.97125	other
CL2001032155AA	other	0.19664	0.80336	other
CL2001032156AA (testset)	other	0.04121	0.95879	other
CL2001032202AA (testset)	NORMAL	0.86762	0.13238	NORMAL
CL2001032206AA	NORMAL	0.78175	0.21825	NORMAL
CL2001032207AA	other	0.0086	0.9914	other
CL2001032209AA	other	0.02141	0.97859	other
CL2001032210AA	other	0.02421	0.97579	other
CL2001032211AA (testset)	other	0.01506	0.98494	other
CL2001032212AA	other	0.00454	0.99546	other
CL2001032213AA	other	0.4155	0.5845	other
CL2001032214AA (testset)	other	0.38881	0.61119	other
CL2001032217AA (testset)	other	0.00708	0.99292	other
CL2001032218AA	other	0.00582	0.99418	other
CL2001032219AA (testset)	other	0.01336	0.98664	other
CL2001032220AA	NORMAL	0.57841	0.42159	NORMAL
CL2001032222AA (testset)	other	0.00638	0.99362	other
CL2001032229AA (testset)	other	0.01396	0.98604	other
CL2001032231AA	other	0.03666	0.96334	other
CL2001032232AA	other	0.01078	0.98922	other
CL2001032233AA (testset)	other	0.0275	0.9725	other
CL2001032238AA	other	0.00246	0.99754	other
CL2001032239AA	other	0.03719	0.96281	other
CL2001032240AA	other	0.02742	0.97258	other
CL2001032241AA (testset)	other	0.07916	0.92084	other
CL2001032242AA	other	0.02947	0.97053	other
CL2001032243AA	other	0.04048	0.95952	other
CL2001032248AA	other	0.00655	0.99345	other
CL2001032249AA (testset)	other	0.02407	0.97593	other
CL2001032252AA (testset)	other	0.07714	0.92286	other
CL2001032254AA (testset)	other	0.07065	0.92935	other
CL2001032255AA	other	0.04159	0.95841	other
CL2001032256AA (testset)	NORMAL	0.31332	0.68668	other
CL2001032259AA (testset)	other	0.0439	0.9561	other
CL2001032260AA	other	0.04917	0.95083	other
CL2001032301AA	other	0.01525	0.98475	other
CL2001032304AA	NORMAL	0.60028	0.39972	NORMAL
CL2001032305AA (testset)	other	0.09265	0.90735	other
CL2001032306AA (testset)	other	0.04683	0.95317	other
CL2001032307AA (testset)	other	0.09849	0.90151	other
CL2001032308AA	other	0.01607	0.98393	other
CL2001032309AA	other	0.01079	0.98921	other
CL2001032310AA	other	0.0043	0.9957	other
CL2001032311AA (testset)	other	0.06951	0.93049	other
CL2001032312AA	other	0.01276	0.98724	other
CL2001032313AA (testset)	other	0.0167	0.9833	other
CL2001032314AA (testset)	other	0.01829	0.98171	other
CL2001032316AA	other	0.02523	0.97477	other
CL2001032601AA	other	0.01962	0.98038	other
CL2001032602AA	other	0.00172	0.99828	other
CL2001032604AA	other	0.00371	0.99629	other
CL2001032607AA	other	0.00667	0.99333	other
CL2001032608AA	other	0.02553	0.97447	other
CL2001032610AA	other	0.0122	0.9878	other
CL2001032612AA	other	0.01024	0.98976	other
CL2001032613AA (testset)	other	0.00838	0.99162	other
CL2001032614AA	other	0.00303	0.99697	other
CL2001032616AA	other	0.00969	0.99031	other
CL2001032617AA (testset)	other	0.00738	0.99262	other
CL2001032620AA (testset)	other	0.02099	0.97901	other
CL2001032625AA	other	0.00223	0.99777	other
CL2001032627AA	other	0.02731	0.97269	other
CL2001032628AA	other	0.0456	0.9544	other
CL2001032629AA	other	0.00195	0.99805	other
CL2001032630AA (testset)	other	0.01752	0.98248	other
CL2001032632AA	other	0.00632	0.99368	other
CL2001032638AA	other	0.01571	0.98429	other
CL2001032640AA (testset)	other	0.00189	0.99811	other
CL2001032643AA	other	0.09352	0.90648	other
CL2001032644AA (testset)	other	0.06534	0.93466	other
CL2001032647AA	other	0.06814	0.93186	other
CL2001032701AA	other	0.01312	0.98688	other
CL2001032702AA	other	0.01524	0.98476	other
CL2001032703AA	other	0.09214	0.90786	other
CL2001032704AA	other	0.09577	0.90423	other
CL2001032706AA (testset)	other	0.01493	0.98507	other
CL2001032709AA	other	0.03623	0.96377	other
CL2001032716AA	other	0.00793	0.99207	other
CL2001032717AA	other	0.01045	0.98955	other
CL2001032718AA (testset)	NORMAL	0.69178	0.30822	NORMAL
CL2001032719AA	other	0.09246	0.90754	other
CL2001032720AA	other	0.00072	0.99928	other
CL2001032722AA	other	0.01858	0.98142	other
CL2001032724AA	NORMAL	0.2747	0.7253	other
CL2001032725AA	NORMAL	0.56555	0.43445	NORMAL
CL2001032727AA	NORMAL	0.59594	0.40406	NORMAL
CL2001032729AA	other	0.0149	0.9851	other
CL2001032730AA (testset)	other	0.01727	0.98273	other
CL2001032732AA (testset)	other	0.00161	0.99839	other
CL2001032733AA	other	0.00413	0.99587	other
CL2001032738AA (testset)	other	0.03704	0.96296	other
CL2001032742AA (testset)	other	0.00558	0.99442	other
CL2001032746AA	other	0.06592	0.93408	other
CL2001032747AA	other	0.00582	0.99418	other
CL2001032833AA	other	0.00906	0.99094	other
CL2001032836AA (testset)	other	0.00296	0.99704	other
CL2001032838AA (testset)	other	0.04475	0.95525	other
CL2001032839AA	other	0.01249	0.98751	other
CL2001032841AA	other	0.03775	0.96225	other
CL2001032842AA	other	0.00175	0.99825	other
CL2001032843AA (testset)	other	0.00217	0.99783	other
CL2001032845AA (testset)	other	0.04243	0.95757	other
CL2001032846AA	other	0.00582	0.99418	other
CL2001032847AA	other	0.05533	0.94467	other
CL2001032848AA	other	0.60037	0.39963	NORMAL
CL2001032850AA	other	0.00732	0.99268	other
CL2001032853AA	other	0.11041	0.88959	other
CL2001032854AA (testset)	other	0.00442	0.99558	other
CL2001032856AA	other	0.08754	0.91246	other
CL2001032857AA	other	0.0097	0.9903	other
CL2001032860AA (testset)	other	0.01404	0.98596	other
CL2001040305AA	other	0.00505	0.99495	other
CL2001040306AA	other	0.0156	0.9844	other
CL2001041708AA	other	0.0103	0.9897	other
CL2001041711AA	other	0.00319	0.99681	other
CL2001041716AA	other	0.07149	0.92851	other
CL2001042501AA (testset)	other	0.00298	0.99702	other
CL2001042505AA	other	0.00336	0.99664	other
CL2001042506AA (testset)	other	0.18275	0.81725	other