GO:0007194

GO:0007194

negative regulation of adenylate cyclase activity (annotated genes)

Biological Process

1 parent node replaced:

GO:0045761	regulation of adenylate cyclase activity

Parent nodes

GO:0043086	negative regulation of enzyme activity
GO:0007193	G-protein signaling, adenylate cyclase inhibiting pathway
GO:0050790	regulation of enzyme activity

This leaf node contains 14 genes

The following 6 of these are used in classification:

	Symbol	Genename	NORMAL score	other score
1198_at	EDNRB	endothelin receptor type B	1.271	-0.1127
37307_at	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	1.0755	-0.0954
39936_at	CCR2	chemokine (C-C motif) receptor 2	0.1782	-0.0158
264_at	ADRA2A	adrenergic, alpha-2A-, receptor	-0.1694	0.015
37149_s_at	CCR2	chemokine (C-C motif) receptor 2	-0.0657	0.0058
32623_at	GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1	0.0115	-0.001

Performance on training data

• Error rate: 0.04444
• Performance: 0.18863
• Redundancy: 3.17243

	Sensitivity	Specificity
NORMAL	0.45455	1
other	1	0.45455

Performance on test data

• Error rate: 0.04412
• Performance: 0.18411
• Redundancy: 3.07925

	Sensitivity	Specificity
NORMAL	0.5	1
other	1	0.5

Predictions

	Class	NORMAL	other	Predictionn
CL2001031606AA	other	0.00821	0.99179	other
CL2001031607AA	other	0.01794	0.98206	other
CL2001031608AA	other	0.02309	0.97691	other
CL2001031609AA	other	0.01117	0.98883	other
CL2001031611AA	other	0.01444	0.98556	other
CL2001031612AA	other	0.034	0.966	other
CL2001031613AA	other	0.18405	0.81595	other
CL2001031615AA	other	0.00671	0.99329	other
CL2001031616AA (testset)	other	0.0304	0.9696	other
CL2001031618AA	other	0.00379	0.99621	other
CL2001031620AA (testset)	other	0.00714	0.99286	other
CL2001031621AA (testset)	other	0.01233	0.98767	other
CL2001031622AA	other	0.00533	0.99467	other
CL2001031625AA	other	0.01079	0.98921	other
CL2001031627AA (testset)	other	0.01317	0.98683	other
CL2001031628AA (testset)	other	0.01602	0.98398	other
CL2001031629AA	other	0.00382	0.99618	other
CL2001031630AA (testset)	other	0.01245	0.98755	other
CL2001031631AA	other	0.02234	0.97766	other
CL2001031632AA	other	0.00708	0.99292	other
CL2001031634AA	other	0.00974	0.99026	other
CL2001031635AA	other	0.05298	0.94702	other
CL2001031636AA	other	0.04746	0.95254	other
CL2001032002AA	other	0.04671	0.95329	other
CL2001032005AA	other	0.00299	0.99701	other
CL2001032008AA	other	0.01312	0.98688	other
CL2001032009AA (testset)	other	0.00348	0.99652	other
CL2001032010AA (testset)	NORMAL	0.66382	0.33618	NORMAL
CL2001032011AA (testset)	other	0.09524	0.90476	other
CL2001032012AA (testset)	other	0.02243	0.97757	other
CL2001032013AA (testset)	other	0.01827	0.98173	other
CL2001032015AA	other	0.16058	0.83942	other
CL2001032016AA (testset)	other	0.00583	0.99417	other
CL2001032019AA	other	0.00533	0.99467	other
CL2001032020AA (testset)	other	0.02971	0.97029	other
CL2001032025AA	other	0.01288	0.98712	other
CL2001032026AA	other	0.0137	0.9863	other
CL2001032027AA	other	0.05578	0.94422	other
CL2001032030AA	other	0.02647	0.97353	other
CL2001032031AA (testset)	other	0.01938	0.98062	other
CL2001032032AA	other	0.00967	0.99033	other
CL2001032034AA	other	0.16356	0.83644	other
CL2001032036AA	other	0.18339	0.81661	other
CL2001032041AA	NORMAL	0.41063	0.58937	other
CL2001032043AA	NORMAL	0.78499	0.21501	NORMAL
CL2001032044AA	other	0.01141	0.98859	other
CL2001032045AA (testset)	NORMAL	0.5921	0.4079	NORMAL
CL2001032046AA	NORMAL	0.64605	0.35395	NORMAL
CL2001032101AA	other	0.20902	0.79098	other
CL2001032102AA	NORMAL	0.48511	0.51489	other
CL2001032103AA	other	0.01424	0.98576	other
CL2001032104AA	other	0.01532	0.98468	other
CL2001032105AA	other	0.00066	0.99934	other
CL2001032107AA	other	0.01772	0.98228	other
CL2001032108AA	other	0.0107	0.9893	other
CL2001032109AA (testset)	other	0.02013	0.97987	other
CL2001032110AA	other	0.06991	0.93009	other
CL2001032111AA	other	0.03343	0.96657	other
CL2001032113AA (testset)	other	0.00115	0.99885	other
CL2001032114AA	other	0.02185	0.97815	other
CL2001032115AA (testset)	other	0.00699	0.99301	other
CL2001032116AA (testset)	other	0.01033	0.98967	other
CL2001032117AA	other	0.00752	0.99248	other
CL2001032121AA	other	0.00536	0.99464	other
CL2001032122AA	other	0.02739	0.97261	other
CL2001032124AA	other	0.04655	0.95345	other
CL2001032125AA	other	0.00198	0.99802	other
CL2001032127AA (testset)	other	0.00767	0.99233	other
CL2001032128AA (testset)	NORMAL	0.35164	0.64836	other
CL2001032129AA (testset)	other	0.01465	0.98535	other
CL2001032130AA	other	0.00826	0.99174	other
CL2001032132AA	other	0.02079	0.97921	other
CL2001032134AA (testset)	other	0.0418	0.9582	other
CL2001032135AA	other	0.07736	0.92264	other
CL2001032136AA (testset)	other	0.04542	0.95458	other
CL2001032138AA (testset)	other	0.05189	0.94811	other
CL2001032141AA (testset)	other	0.01141	0.98859	other
CL2001032142AA	other	0.00433	0.99567	other
CL2001032144AA	other	0.00508	0.99492	other
CL2001032145AA	other	0.00706	0.99294	other
CL2001032147AA	NORMAL	0.63589	0.36411	NORMAL
CL2001032149AA (testset)	other	0.09889	0.90111	other
CL2001032151AA	other	0.00623	0.99377	other
CL2001032152AA	other	0.00787	0.99213	other
CL2001032153AA	other	0.00716	0.99284	other
CL2001032155AA	other	0.33824	0.66176	other
CL2001032156AA (testset)	other	0.0381	0.9619	other
CL2001032202AA (testset)	NORMAL	0.37437	0.62563	other
CL2001032206AA	NORMAL	0.43378	0.56622	other
CL2001032207AA	other	0.00683	0.99317	other
CL2001032209AA	other	0.01858	0.98142	other
CL2001032210AA	other	0.0076	0.9924	other
CL2001032211AA (testset)	other	0.01046	0.98954	other
CL2001032212AA	other	0.00353	0.99647	other
CL2001032213AA	other	0.15838	0.84162	other
CL2001032214AA (testset)	other	0.07231	0.92769	other
CL2001032217AA (testset)	other	0.00188	0.99812	other
CL2001032218AA	other	0.00698	0.99302	other
CL2001032219AA (testset)	other	0.00618	0.99382	other
CL2001032220AA	NORMAL	0.28249	0.71751	other
CL2001032222AA (testset)	other	0.00288	0.99712	other
CL2001032229AA (testset)	other	0.00832	0.99168	other
CL2001032231AA	other	0.06819	0.93181	other
CL2001032232AA	other	0.0083	0.9917	other
CL2001032233AA (testset)	other	0.0095	0.9905	other
CL2001032238AA	other	0.00982	0.99018	other
CL2001032239AA	other	0.07712	0.92288	other
CL2001032240AA	other	0.03841	0.96159	other
CL2001032241AA (testset)	other	0.03978	0.96022	other
CL2001032242AA	other	0.03912	0.96088	other
CL2001032243AA	other	0.01141	0.98859	other
CL2001032248AA	other	0.01426	0.98574	other
CL2001032249AA (testset)	other	0.02316	0.97684	other
CL2001032252AA (testset)	other	0.00875	0.99125	other
CL2001032254AA (testset)	other	0.01482	0.98518	other
CL2001032255AA	other	0.00722	0.99278	other
CL2001032256AA (testset)	NORMAL	0.16975	0.83025	other
CL2001032259AA (testset)	other	0.07964	0.92036	other
CL2001032260AA	other	0.05765	0.94235	other
CL2001032301AA	other	0.03165	0.96835	other
CL2001032304AA	NORMAL	0.26138	0.73862	other
CL2001032305AA (testset)	other	0.02263	0.97737	other
CL2001032306AA (testset)	other	0.02314	0.97686	other
CL2001032307AA (testset)	other	0.08978	0.91022	other
CL2001032308AA	other	0.01031	0.98969	other
CL2001032309AA	other	0.00519	0.99481	other
CL2001032310AA	other	0.00908	0.99092	other
CL2001032311AA (testset)	other	0.03113	0.96887	other
CL2001032312AA	other	0.00552	0.99448	other
CL2001032313AA (testset)	other	0.01306	0.98694	other
CL2001032314AA (testset)	other	0.01708	0.98292	other
CL2001032316AA	other	0.0052	0.9948	other
CL2001032601AA	other	0.00614	0.99386	other
CL2001032602AA	other	0.00091	0.99909	other
CL2001032604AA	other	0.00254	0.99746	other
CL2001032607AA	other	0.002	0.998	other
CL2001032608AA	other	0.03625	0.96375	other
CL2001032610AA	other	0.00502	0.99498	other
CL2001032612AA	other	0.00334	0.99666	other
CL2001032613AA (testset)	other	0.02265	0.97735	other
CL2001032614AA	other	0.00227	0.99773	other
CL2001032616AA	other	0.00903	0.99097	other
CL2001032617AA (testset)	other	0.02104	0.97896	other
CL2001032620AA (testset)	other	0.01859	0.98141	other
CL2001032625AA	other	0.00286	0.99714	other
CL2001032627AA	other	0.0118	0.9882	other
CL2001032628AA	other	0.0062	0.9938	other
CL2001032629AA	other	0.00224	0.99776	other
CL2001032630AA (testset)	other	0.04217	0.95783	other
CL2001032632AA	other	0.00602	0.99398	other
CL2001032638AA	other	0.00212	0.99788	other
CL2001032640AA (testset)	other	0.00916	0.99084	other
CL2001032643AA	other	0.03315	0.96685	other
CL2001032644AA (testset)	other	0.01645	0.98355	other
CL2001032647AA	other	0.07161	0.92839	other
CL2001032701AA	other	0.01487	0.98513	other
CL2001032702AA	other	0.03344	0.96656	other
CL2001032703AA	other	0.0592	0.9408	other
CL2001032704AA	other	0.04926	0.95074	other
CL2001032706AA (testset)	other	0.01552	0.98448	other
CL2001032709AA	other	0.02867	0.97133	other
CL2001032716AA	other	0.01352	0.98648	other
CL2001032717AA	other	0.0162	0.9838	other
CL2001032718AA (testset)	NORMAL	0.94549	0.05451	NORMAL
CL2001032719AA	other	0.08044	0.91956	other
CL2001032720AA	other	0.00454	0.99546	other
CL2001032722AA	other	0.02454	0.97546	other
CL2001032724AA	NORMAL	0.35125	0.64875	other
CL2001032725AA	NORMAL	0.78832	0.21168	NORMAL
CL2001032727AA	NORMAL	0.53461	0.46539	NORMAL
CL2001032729AA	other	0.01862	0.98138	other
CL2001032730AA (testset)	other	0.00367	0.99633	other
CL2001032732AA (testset)	other	0.00373	0.99627	other
CL2001032733AA	other	0.00439	0.99561	other
CL2001032738AA (testset)	other	0.01188	0.98812	other
CL2001032742AA (testset)	other	0.01481	0.98519	other
CL2001032746AA	other	0.01176	0.98824	other
CL2001032747AA	other	0.00828	0.99172	other
CL2001032833AA	other	0.03331	0.96669	other
CL2001032836AA (testset)	other	0.00735	0.99265	other
CL2001032838AA (testset)	other	0.0729	0.9271	other
CL2001032839AA	other	0.01432	0.98568	other
CL2001032841AA	other	0.02034	0.97966	other
CL2001032842AA	other	0.00918	0.99082	other
CL2001032843AA (testset)	other	0.03672	0.96328	other
CL2001032845AA (testset)	other	0.1271	0.8729	other
CL2001032846AA	other	0.02765	0.97235	other
CL2001032847AA	other	0.20467	0.79533	other
CL2001032848AA	other	0.40708	0.59292	other
CL2001032850AA	other	0.02964	0.97036	other
CL2001032853AA	other	0.01952	0.98048	other
CL2001032854AA (testset)	other	0.04194	0.95806	other
CL2001032856AA	other	0.04403	0.95597	other
CL2001032857AA	other	0.0228	0.9772	other
CL2001032860AA (testset)	other	0.05909	0.94091	other
CL2001040305AA	other	0.00364	0.99636	other
CL2001040306AA	other	0.02819	0.97181	other
CL2001041708AA	other	0.00971	0.99029	other
CL2001041711AA	other	0.00446	0.99554	other
CL2001041716AA	other	0.0827	0.9173	other
CL2001042501AA (testset)	other	0.01604	0.98396	other
CL2001042505AA	other	0.00198	0.99802	other
CL2001042506AA (testset)	other	0.11798	0.88202	other