GO:0006886

GO:0006886

intracellular protein transport (annotated genes)

Biological Process

Parent node

GO:0006886	intracellular protein transport

This leaf node contains 212 genes

The following 123 of these are used in classification:

	Symbol	Genename	NORMAL score	other score
41549_s_at	AP1S2	adaptor-related protein complex 1, sigma 2 subunit	0.8941	-0.0793
39857_at	STX11	syntaxin 11	0.8731	-0.0775
33802_at	TOM1	target of myb1 (chicken)	0.7693	-0.0682
38635_at	SSR4	signal sequence receptor, delta (translocon-associated protein delta)	-0.7433	0.0659
38164_at	RPGR	retinitis pigmentosa GTPase regulator	0.7103	-0.063
35325_at	RAB14	RAB14, member RAS oncogene family	0.606	-0.0538
38774_at	STX7	syntaxin 7	0.6026	-0.0535
41462_at	SNX2	sorting nexin 2	0.5354	-0.0475
40407_at	KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	-0.5308	0.0471
40278_at	GGA2	golgi associated, gamma adaptin ear containing, ARF binding protein 2	0.5227	-0.0464
40229_at	TOM1L1	target of myb1-like 1 (chicken)	-0.4663	0.0414
39360_at	SNX3	sorting nexin 3	0.4414	-0.0392
39214_at	SSR4	signal sequence receptor, delta (translocon-associated protein delta)	-0.4381	0.0389
1074_at	RAB1A	RAB1A, member RAS oncogene family	-0.4339	0.0385
34478_at	RAB11B	RAB11B, member RAS oncogene family	-0.4336	0.0385
1840_g_at	RAN	RAN, member RAS oncogene family	-0.4306	0.0382
39858_s_at	STX11	syntaxin 11	0.4146	-0.0368
35340_at	RAB8A	RAB8A, member RAS oncogene family	0.414	-0.0367
40926_at	BCAP31	B-cell receptor-associated protein 31	-0.4126	0.0366
37184_at	STX1A	syntaxin 1A (brain)	-0.4072	0.0361
38798_s_at	AP1G2	adaptor-related protein complex 1, gamma 2 subunit	-0.4049	0.0359
1839_at	RAN	RAN, member RAS oncogene family	-0.3929	0.0349
41864_at	EPIM	epimorphin	0.3865	-0.0343
36660_at	RAB11A	RAB11A, member RAS oncogene family	0.3858	-0.0342
35304_at	RAB6A	RAB6A, member RAS oncogene family	0.3818	-0.0339
33402_at	KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	-0.3765	0.0334
36128_at	TMP21	transmembrane trafficking protein	-0.3764	0.0334
41163_at	P24B	integral type I protein	-0.3594	0.0319
32219_at	TLK1	tousled-like kinase 1	-0.3339	0.0296
38259_at	STXBP2	syntaxin binding protein 2	0.3333	-0.0296
37654_at	SNX17	sorting nexin 17	0.3282	-0.0291
39523_at	STX16	syntaxin 16	-0.3255	0.0289
36977_at	NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.3187	-0.0283
38719_at	NSF	N-ethylmaleimide-sensitive factor	-0.2952	0.0262
41251_at	TRIP3	thyroid hormone receptor interactor 3	-0.2638	0.0234
35166_at	DSCR3	Down syndrome critical region gene 3	0.2629	-0.0233
33434_at	BET1	BET1 homolog (S. cerevisiae)	-0.2506	0.0222
34895_at	SEC23IP	SEC23 interacting protein	-0.2321	0.0206
38804_at	CSE1L	CSE1 chromosome segregation 1-like (yeast)	-0.2284	0.0203
623_s_at	RAB2	RAB2, member RAS oncogene family	-0.2235	0.0198
38708_at	RAN	RAN, member RAS oncogene family	-0.222	0.0197
41121_at	STX16	syntaxin 16	-0.2092	0.0186
35790_at	VPS26	vacuolar protein sorting 26 (yeast)	0.2066	-0.0183
35642_at	MTX2	metaxin 2	-0.2007	0.0178
37973_at	SNX13	sorting nexin 13	-0.1881	0.0167
39025_at	TOMM7	translocase of outer mitochondrial membrane 7 homolog (yeast)	0.1809	-0.016
32762_i_at	RAB3-GAP150	rab3 GTPase-activating protein, non-catalytic subunit (150kD)	-0.1804	0.016
33877_s_at	EXOC7	exocyst complex component 7	-0.1773	0.0157
41451_s_at	SARA1	SAR1a gene homolog 1 (S. cerevisiae)	-0.1746	0.0155
40885_s_at	STX16	syntaxin 16	-0.1731	0.0154
35297_at	GGA2	golgi associated, gamma adaptin ear containing, ARF binding protein 2	-0.1727	0.0153
33349_at	TNPO1	transportin 1	0.1635	-0.0145
37911_at	STX4A	syntaxin 4A (placental)	0.162	-0.0144
38471_r_at	APPBP2	amyloid beta precursor protein (cytoplasmic tail) binding protein 2	0.162	-0.0144
36972_at	RNP24	coated vesicle membrane protein	-0.1595	0.0141
37386_i_at	KDELR1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	-0.155	0.0138
34836_at	RAB5C	RAB5C, member RAS oncogene family	0.1539	-0.0137
624_at	RAB3B	RAB3B, member RAS oncogene family	-0.1511	0.0134
34393_r_at	RAB1A	RAB1A, member RAS oncogene family	-0.15	0.0133
36049_at	RAB6B	RAB6B, member RAS oncogene family	-0.1477	0.0131
31662_at	VPS45A	vacuolar protein sorting 45A (yeast)	-0.1386	0.0123
40289_at	NAPG	N-ethylmaleimide-sensitive factor attachment protein, gamma	-0.136	0.0121
35620_at	TOMM40	translocase of outer mitochondrial membrane 40 homolog (yeast)	-0.1349	0.012
34052_at	EPIM	epimorphin	0.1304	-0.0116
34326_at	COPB	coatomer protein complex, subunit beta	-0.1294	0.0115
38264_at	RABIF	RAB interacting factor	-0.127	0.0113
39490_f_at	ARFGAP3	ADP-ribosylation factor GTPase activating protein 3	-0.1261	0.0112
620_at	RAB3A	RAB3A, member RAS oncogene family	-0.1227	0.0109
34737_at	COG5	component of oligomeric golgi complex 5	-0.122	0.0108
600_at	RAB5A	RAB5A, member RAS oncogene family	-0.1215	0.0108
39272_g_at	RAB4B	RAB4B, member RAS oncogene family	0.1211	-0.0107
39975_at	GGA2	golgi associated, gamma adaptin ear containing, ARF binding protein 2	-0.1197	0.0106
40068_at	STX5A	syntaxin 5A	0.1186	-0.0105
39130_at	VPS39	vacuolar protein sorting 39 (yeast)	0.1161	-0.0103
39307_s_at	CLTB	clathrin, light polypeptide (Lcb)	0.1117	-0.0099
35445_at	SNX26	sorting nexin 26	-0.1111	0.0099
37387_r_at	KDELR1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	-0.1092	0.0097
35754_at	TMP21	transmembrane trafficking protein	0.1065	-0.0094
36498_at	AP1S1	adaptor-related protein complex 1, sigma 1 subunit	-0.1043	0.0093
35845_at	SEC24B	SEC24 related gene family, member B (S. cerevisiae)	0.1041	-0.0092
32522_f_at	CLTB	clathrin, light polypeptide (Lcb)	0.1021	-0.0091
980_at	NPC1	Niemann-Pick disease, type C1	0.0996	-0.0088
37047_at	NPC1	Niemann-Pick disease, type C1	0.0963	-0.0085
32770_at	SEC24D	SEC24 related gene family, member D (S. cerevisiae)	-0.0941	0.0083
35725_at	KPNA3	karyopherin alpha 3 (importin alpha 4)	0.0911	-0.0081
33942_s_at	STXBP1	syntaxin binding protein 1	0.0881	-0.0078
37959_at	GGA3	golgi associated, gamma adaptin ear containing, ARF binding protein 3	0.0872	-0.0077
32523_at	CLTB	clathrin, light polypeptide (Lcb)	0.0857	-0.0076
33435_r_at	BET1	BET1 homolog (S. cerevisiae)	-0.0803	0.0071
38911_at	NUP98	nucleoporin 98kDa	0.0791	-0.007
38470_i_at	APPBP2	amyloid beta precursor protein (cytoplasmic tail) binding protein 2	0.0721	-0.0064
40883_at	STX16	syntaxin 16	-0.0707	0.0063
36110_at	RAB5A	RAB5A, member RAS oncogene family	0.0666	-0.0059
38525_at	STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	-0.0653	0.0058
39134_at	TOM1	target of myb1 (chicken)	0.0603	-0.0053
37464_at	PEX13	peroxisome biogenesis factor 13	-0.059	0.0052
34159_at	RAB7	RAB7, member RAS oncogene family	-0.0569	0.005
35443_at	KPNA6	karyopherin alpha 6 (importin alpha 7)	-0.0546	0.0048
39905_i_at	ARFGAP3	ADP-ribosylation factor GTPase activating protein 3	-0.0531	0.0047
33740_at	SCAMP3	secretory carrier membrane protein 3	-0.0484	0.0043
40851_r_at	SEC23B	Sec23 homolog B (S. cerevisiae)	-0.0477	0.0042
40931_at	CGI-100	CGI-100 protein	0.0473	-0.0042
35446_at	SNX26	sorting nexin 26	-0.0467	0.0041
35383_at	NBR2	neighbor of BRCA1 gene 2	-0.0438	0.0039
41548_at	AP1S2	adaptor-related protein complex 1, sigma 2 subunit	0.0402	-0.0036
39934_at	RAB36	RAB36, member RAS oncogene family	0.0397	-0.0035
34392_s_at	RAB1A	RAB1A, member RAS oncogene family	-0.0396	0.0035
38799_at	AP1G2	adaptor-related protein complex 1, gamma 2 subunit	-0.0386	0.0034
38718_at	COG4	component of oligomeric golgi complex 4	-0.0371	0.0033
34753_at	SYBL1	synaptobrevin-like 1	0.0361	-0.0032
32030_at	AP3S2	adaptor-related protein complex 3, sigma 2 subunit	-0.0282	0.0025
35886_at	PACSIN2	protein kinase C and casein kinase substrate in neurons 2	-0.0281	0.0025
622_at	RAB6A	RAB6A, member RAS oncogene family	-0.0277	0.0025
38117_at	SEC24C	SEC24 related gene family, member C (S. cerevisiae)	0.0249	-0.0022
39795_at	AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.0195	-0.0017
40654_at	PEX7	peroxisomal biogenesis factor 7	-0.0149	0.0013
31858_at	NUTF2	nuclear transport factor 2	-0.0145	0.0013
39099_at	SEC23A	Sec23 homolog A (S. cerevisiae)	-0.0129	0.0011
31606_at	RIMS1	regulating synaptic membrane exocytosis 1	-0.0114	0.001
40277_at	GGA2	golgi associated, gamma adaptin ear containing, ARF binding protein 2	0.0099	-9e-04
36216_at	SNX4	sorting nexin 4	-0.0055	5e-04
40463_at	TNPO1	transportin 1	-0.004	4e-04
40563_at	NUP50	nucleoporin 50kDa	-0.0018	2e-04

Performance on training data

• Error rate: 0.01481
• Performance: 0.17194
• Redundancy: 4.07034

	Sensitivity	Specificity
NORMAL	1	0.98387
other	0.98387	1

Performance on test data

• Error rate: 0.01471
• Performance: 0.09984
• Redundancy: 4.02797

	Sensitivity	Specificity
NORMAL	0.83333	1
other	1	0.83333

Predictions

	Class	NORMAL	other	Predictionn
CL2001031606AA	other	1e-05	0.99999	other
CL2001031607AA	other	0.00759	0.99241	other
CL2001031608AA	other	0.01126	0.98874	other
CL2001031609AA	other	4e-04	0.9996	other
CL2001031611AA	other	0.00021	0.99979	other
CL2001031612AA	other	0.00487	0.99513	other
CL2001031613AA	other	0.27349	0.72651	other
CL2001031615AA	other	0.00055	0.99945	other
CL2001031616AA (testset)	other	0.00035	0.99965	other
CL2001031618AA	other	0.00131	0.99869	other
CL2001031620AA (testset)	other	0.00014	0.99986	other
CL2001031621AA (testset)	other	3e-05	0.99997	other
CL2001031622AA	other	5e-05	0.99995	other
CL2001031625AA	other	7e-05	0.99993	other
CL2001031627AA (testset)	other	9e-05	0.99991	other
CL2001031628AA (testset)	other	1e-05	0.99999	other
CL2001031629AA	other	0	1	other
CL2001031630AA (testset)	other	8e-05	0.99992	other
CL2001031631AA	other	0	1	other
CL2001031632AA	other	0.00058	0.99942	other
CL2001031634AA	other	3e-05	0.99997	other
CL2001031635AA	other	0.00048	0.99952	other
CL2001031636AA	other	0.00046	0.99954	other
CL2001032002AA	other	0.00018	0.99982	other
CL2001032005AA	other	0	1	other
CL2001032008AA	other	1e-05	0.99999	other
CL2001032009AA (testset)	other	0	1	other
CL2001032010AA (testset)	NORMAL	0.98528	0.01472	NORMAL
CL2001032011AA (testset)	other	0.02072	0.97928	other
CL2001032012AA (testset)	other	0.19072	0.80928	other
CL2001032013AA (testset)	other	0.02258	0.97742	other
CL2001032015AA	other	0.06124	0.93876	other
CL2001032016AA (testset)	other	1e-05	0.99999	other
CL2001032019AA	other	3e-05	0.99997	other
CL2001032020AA (testset)	other	1e-04	0.9999	other
CL2001032025AA	other	7e-04	0.9993	other
CL2001032026AA	other	0.00014	0.99986	other
CL2001032027AA	other	0.00211	0.99789	other
CL2001032030AA	other	1e-05	0.99999	other
CL2001032031AA (testset)	other	0.00107	0.99893	other
CL2001032032AA	other	0.00602	0.99398	other
CL2001032034AA	other	0.31336	0.68664	other
CL2001032036AA	other	0.00567	0.99433	other
CL2001032041AA	NORMAL	0.99882	0.00118	NORMAL
CL2001032043AA	NORMAL	0.99935	0.00065	NORMAL
CL2001032044AA	other	0.00022	0.99978	other
CL2001032045AA (testset)	NORMAL	0.99947	0.00053	NORMAL
CL2001032046AA	NORMAL	0.99987	0.00013	NORMAL
CL2001032101AA	other	0.01345	0.98655	other
CL2001032102AA	NORMAL	0.99918	0.00082	NORMAL
CL2001032103AA	other	0.10608	0.89392	other
CL2001032104AA	other	0.00041	0.99959	other
CL2001032105AA	other	1e-05	0.99999	other
CL2001032107AA	other	0	1	other
CL2001032108AA	other	0.00543	0.99457	other
CL2001032109AA (testset)	other	0.14026	0.85974	other
CL2001032110AA	other	0.00732	0.99268	other
CL2001032111AA	other	0.00026	0.99974	other
CL2001032113AA (testset)	other	0	1	other
CL2001032114AA	other	0.00121	0.99879	other
CL2001032115AA (testset)	other	2e-05	0.99998	other
CL2001032116AA (testset)	other	4e-05	0.99996	other
CL2001032117AA	other	0	1	other
CL2001032121AA	other	0	1	other
CL2001032122AA	other	0	1	other
CL2001032124AA	other	5e-05	0.99995	other
CL2001032125AA	other	0	1	other
CL2001032127AA (testset)	other	9e-05	0.99991	other
CL2001032128AA (testset)	NORMAL	0.99521	0.00479	NORMAL
CL2001032129AA (testset)	other	5e-05	0.99995	other
CL2001032130AA	other	1e-05	0.99999	other
CL2001032132AA	other	2e-05	0.99998	other
CL2001032134AA (testset)	other	0.00067	0.99933	other
CL2001032135AA	other	0.00028	0.99972	other
CL2001032136AA (testset)	other	0.00105	0.99895	other
CL2001032138AA (testset)	other	1e-04	0.9999	other
CL2001032141AA (testset)	other	0	1	other
CL2001032142AA	other	0.00023	0.99977	other
CL2001032144AA	other	5e-05	0.99995	other
CL2001032145AA	other	3e-04	0.9997	other
CL2001032147AA	NORMAL	0.99985	0.00015	NORMAL
CL2001032149AA (testset)	other	0.0025	0.9975	other
CL2001032151AA	other	5e-05	0.99995	other
CL2001032152AA	other	0.00188	0.99812	other
CL2001032153AA	other	0.00022	0.99978	other
CL2001032155AA	other	0.98799	0.01201	NORMAL
CL2001032156AA (testset)	other	0.00496	0.99504	other
CL2001032202AA (testset)	NORMAL	0.99939	0.00061	NORMAL
CL2001032206AA	NORMAL	0.99878	0.00122	NORMAL
CL2001032207AA	other	1e-05	0.99999	other
CL2001032209AA	other	1e-05	0.99999	other
CL2001032210AA	other	0.00017	0.99983	other
CL2001032211AA (testset)	other	0	1	other
CL2001032212AA	other	1e-05	0.99999	other
CL2001032213AA	other	0.06875	0.93125	other
CL2001032214AA (testset)	other	0.007	0.993	other
CL2001032217AA (testset)	other	0.00045	0.99955	other
CL2001032218AA	other	2e-05	0.99998	other
CL2001032219AA (testset)	other	0.00149	0.99851	other
CL2001032220AA	NORMAL	0.99997	3e-05	NORMAL
CL2001032222AA (testset)	other	0	1	other
CL2001032229AA (testset)	other	0.00019	0.99981	other
CL2001032231AA	other	0.00205	0.99795	other
CL2001032232AA	other	1e-05	0.99999	other
CL2001032233AA (testset)	other	8e-05	0.99992	other
CL2001032238AA	other	0.00036	0.99964	other
CL2001032239AA	other	0.00033	0.99967	other
CL2001032240AA	other	5e-05	0.99995	other
CL2001032241AA (testset)	other	0.00238	0.99762	other
CL2001032242AA	other	1e-05	0.99999	other
CL2001032243AA	other	1e-05	0.99999	other
CL2001032248AA	other	0	1	other
CL2001032249AA (testset)	other	1e-05	0.99999	other
CL2001032252AA (testset)	other	0	1	other
CL2001032254AA (testset)	other	1e-04	0.9999	other
CL2001032255AA	other	2e-05	0.99998	other
CL2001032256AA (testset)	NORMAL	0.06292	0.93708	other
CL2001032259AA (testset)	other	0.06403	0.93597	other
CL2001032260AA	other	0.01563	0.98437	other
CL2001032301AA	other	0.00101	0.99899	other
CL2001032304AA	NORMAL	0.99232	0.00768	NORMAL
CL2001032305AA (testset)	other	0.00368	0.99632	other
CL2001032306AA (testset)	other	0.00062	0.99938	other
CL2001032307AA (testset)	other	0.19384	0.80616	other
CL2001032308AA	other	0	1	other
CL2001032309AA	other	0.00594	0.99406	other
CL2001032310AA	other	0.00011	0.99989	other
CL2001032311AA (testset)	other	4e-05	0.99996	other
CL2001032312AA	other	1e-05	0.99999	other
CL2001032313AA (testset)	other	2e-05	0.99998	other
CL2001032314AA (testset)	other	0.00031	0.99969	other
CL2001032316AA	other	0.00011	0.99989	other
CL2001032601AA	other	0.00012	0.99988	other
CL2001032602AA	other	0	1	other
CL2001032604AA	other	1e-05	0.99999	other
CL2001032607AA	other	0.00034	0.99966	other
CL2001032608AA	other	9e-05	0.99991	other
CL2001032610AA	other	0.01137	0.98863	other
CL2001032612AA	other	0.00066	0.99934	other
CL2001032613AA (testset)	other	0	1	other
CL2001032614AA	other	0	1	other
CL2001032616AA	other	0.00043	0.99957	other
CL2001032617AA (testset)	other	0	1	other
CL2001032620AA (testset)	other	0.00017	0.99983	other
CL2001032625AA	other	1e-05	0.99999	other
CL2001032627AA	other	1e-05	0.99999	other
CL2001032628AA	other	8e-05	0.99992	other
CL2001032629AA	other	0.00089	0.99911	other
CL2001032630AA (testset)	other	0.00033	0.99967	other
CL2001032632AA	other	6e-05	0.99994	other
CL2001032638AA	other	4e-04	0.9996	other
CL2001032640AA (testset)	other	0	1	other
CL2001032643AA	other	5e-05	0.99995	other
CL2001032644AA (testset)	other	6e-05	0.99994	other
CL2001032647AA	other	0.00434	0.99566	other
CL2001032701AA	other	4e-05	0.99996	other
CL2001032702AA	other	1e-05	0.99999	other
CL2001032703AA	other	2e-05	0.99998	other
CL2001032704AA	other	1e-04	0.9999	other
CL2001032706AA (testset)	other	3e-05	0.99997	other
CL2001032709AA	other	6e-05	0.99994	other
CL2001032716AA	other	0.00011	0.99989	other
CL2001032717AA	other	0.00043	0.99957	other
CL2001032718AA (testset)	NORMAL	0.99868	0.00132	NORMAL
CL2001032719AA	other	0.04609	0.95391	other
CL2001032720AA	other	0.00036	0.99964	other
CL2001032722AA	other	0.00084	0.99916	other
CL2001032724AA	NORMAL	0.99681	0.00319	NORMAL
CL2001032725AA	NORMAL	0.99928	0.00072	NORMAL
CL2001032727AA	NORMAL	0.99943	0.00057	NORMAL
CL2001032729AA	other	0.00015	0.99985	other
CL2001032730AA (testset)	other	0	1	other
CL2001032732AA (testset)	other	4e-05	0.99996	other
CL2001032733AA	other	1e-05	0.99999	other
CL2001032738AA (testset)	other	1e-05	0.99999	other
CL2001032742AA (testset)	other	2e-05	0.99998	other
CL2001032746AA	other	1e-05	0.99999	other
CL2001032747AA	other	1e-05	0.99999	other
CL2001032833AA	other	0.00516	0.99484	other
CL2001032836AA (testset)	other	1e-05	0.99999	other
CL2001032838AA (testset)	other	6e-05	0.99994	other
CL2001032839AA	other	1e-04	0.9999	other
CL2001032841AA	other	4e-05	0.99996	other
CL2001032842AA	other	7e-05	0.99993	other
CL2001032843AA (testset)	other	1e-05	0.99999	other
CL2001032845AA (testset)	other	0.00139	0.99861	other
CL2001032846AA	other	4e-05	0.99996	other
CL2001032847AA	other	0.00238	0.99762	other
CL2001032848AA	other	0.99758	0.00242	NORMAL
CL2001032850AA	other	0.00223	0.99777	other
CL2001032853AA	other	0.00477	0.99523	other
CL2001032854AA (testset)	other	6e-05	0.99994	other
CL2001032856AA	other	0.00036	0.99964	other
CL2001032857AA	other	0.00071	0.99929	other
CL2001032860AA (testset)	other	2e-04	0.9998	other
CL2001040305AA	other	1e-05	0.99999	other
CL2001040306AA	other	5e-05	0.99995	other
CL2001041708AA	other	6e-05	0.99994	other
CL2001041711AA	other	0.01484	0.98516	other
CL2001041716AA	other	0.00242	0.99758	other
CL2001042501AA (testset)	other	0.00039	0.99961	other
CL2001042505AA	other	0.00051	0.99949	other
CL2001042506AA (testset)	other	0.09086	0.90914	other