GO:0007186


GO:0007186

G-protein coupled receptor protein signaling pathway
(annotated genes)

Biological
Process

Parent node

This leaf node contains 273 genes

The following 41 of these are used in classification:

 SymbolGenenameCARCINOID scoreother score
36751_atRGS11 regulator of G-protein signalling 111.5479-0.1776
32886_atGCGR glucagon receptor1.4444-0.1657
41288_atCALM1 calmodulin 1 (phosphorylase kinase, delta)1.3581-0.1559
35272_atGNG5 guanine nucleotide binding protein (G protein), gamma 5-1.33210.1529
38279_atGNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide1.2538-0.1439
41144_g_atCALM1 calmodulin 1 (phosphorylase kinase, delta)1.0572-0.1213
38176_atGNB5 guanine nucleotide binding protein (G protein), beta 50.9879-0.1134
649_s_atCXCR4 chemokine (C-X-C motif) receptor 4-0.83380.0957
40365_atGNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)-0.7770.0892
37187_atCXCL2 chemokine (C-X-C motif) ligand 2-0.77280.0887
36544_atARL3 ADP-ribosylation factor-like 30.6747-0.0774
34268_atRGS19 regulator of G-protein signalling 19-0.66560.0764
32902_atSCTR secretin receptor0.4113-0.0472
33944_atAPLP2 amyloid beta (A4) precursor-like protein 2-0.39640.0455
35128_atBRS3 bombesin-like receptor 30.3778-0.0434
37450_r_atGNAS GNAS complex locus0.3536-0.0406
1564_atAKT1 v-akt murine thymoma viral oncogene homolog 1-0.31590.0363
36103_atCCL3 chemokine (C-C motif) ligand 3-0.26250.0301
37449_i_atGNAS GNAS complex locus0.2504-0.0287
37769_atEDG4 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4-0.20770.0238
37219_atCXCL9 chemokine (C-X-C motif) ligand 9-0.18950.0217
408_atCXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)-0.17820.0204
32666_atCXCL12 chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)-0.1760.0202
36277_atCD3E CD3E antigen, epsilon polypeptide (TiT3 complex)-0.16320.0187
37448_s_atGNAS GNAS complex locus0.162-0.0186
794_atPTPN6 protein tyrosine phosphatase, non-receptor type 6-0.14480.0166
1445_atCCRL2 chemokine (C-C motif) receptor-like 2-0.12370.0142
931_atEBI2 Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor)-0.1220.014
564_atGNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)0.1205-0.0138
35372_r_atIL8 interleukin 8-0.11410.0131
31919_atH963 platelet activating receptor homolog-0.11340.013
37983_atAGTR1 angiotensin II receptor, type 10.0704-0.0081
628_atFZD2 frizzled homolog 2 (Drosophila)-0.06010.0069
39936_atCCR2 chemokine (C-C motif) receptor 2-0.03040.0035
1369_s_atIL8 interleukin 8-0.02980.0034
36324_atADORA2B adenosine A2b receptor-0.02450.0028
36724_s_atCCR2 chemokine (C-C motif) receptor 2-0.01940.0022
37149_s_atCCR2 chemokine (C-C motif) receptor 2-0.01790.0021
37447_atGPR30 G protein-coupled receptor 300.0107-0.0012
36390_atCMKLR1 chemokine-like receptor 1-0.0078e-04
32351_atGPR20 G protein-coupled receptor 200.0023-3e-04

Performance on training data

 SensitivitySpecificity
CARCINOID11
other11

Performance on test data

 SensitivitySpecificity
CARCINOID10.98361
other0.983611

Predictions

 ClassCARCINOIDotherPredictionn
CL2001031606AA (testset)other01 other
CL2001031607AAother01 other
CL2001031608AAother01 other
CL2001031609AACARCINOID10 CARCINOID
CL2001031611AAother01 other
CL2001031612AA (testset)other01 other
CL2001031613AAother01 other
CL2001031615AAother0.000250.99975 other
CL2001031616AAother01 other
CL2001031618AAother2e-050.99998 other
CL2001031620AA (testset)other01 other
CL2001031621AAother2e-050.99998 other
CL2001031622AA (testset)other01 other
CL2001031625AAother01 other
CL2001031627AAother01 other
CL2001031628AAother01 other
CL2001031629AAother1e-050.99999 other
CL2001031630AAother1e-050.99999 other
CL2001031631AAother01 other
CL2001031632AAother01 other
CL2001031634AAother01 other
CL2001031635AA (testset)other01 other
CL2001031636AA (testset)other01 other
CL2001032002AA (testset)other0.00490.9951 other
CL2001032005AA (testset)other1e-050.99999 other
CL2001032008AAother1e-050.99999 other
CL2001032009AA (testset)other0.000390.99961 other
CL2001032010AAother01 other
CL2001032011AAother01 other
CL2001032012AA (testset)other01 other
CL2001032013AA (testset)other01 other
CL2001032015AAother3e-050.99997 other
CL2001032016AAother4e-050.99996 other
CL2001032019AAother01 other
CL2001032020AA (testset)other01 other
CL2001032025AAother0.01240.9876 other
CL2001032026AAother2e-050.99998 other
CL2001032027AA (testset)other01 other
CL2001032030AAother01 other
CL2001032031AAother01 other
CL2001032032AA (testset)other01 other
CL2001032034AAother01 other
CL2001032036AAother0.011320.98868 other
CL2001032041AAother01 other
CL2001032043AAother0.000190.99981 other
CL2001032044AA (testset)CARCINOID10 CARCINOID
CL2001032045AAother01 other
CL2001032046AAother01 other
CL2001032101AACARCINOID10 CARCINOID
CL2001032102AAother1e-050.99999 other
CL2001032103AAother01 other
CL2001032104AAother01 other
CL2001032105AA (testset)other2e-050.99998 other
CL2001032107AAother01 other
CL2001032108AAother01 other
CL2001032109AA (testset)other2e-050.99998 other
CL2001032110AA (testset)other01 other
CL2001032111AAother01 other
CL2001032113AAother1e-050.99999 other
CL2001032114AAother01 other
CL2001032115AAother0.000880.99912 other
CL2001032116AAother1e-050.99999 other
CL2001032117AA (testset)other7e-050.99993 other
CL2001032121AA (testset)other0.723830.27617 CARCINOID
CL2001032122AAother01 other
CL2001032124AACARCINOID10 CARCINOID
CL2001032125AAother0.009680.99032 other
CL2001032127AA (testset)CARCINOID10 CARCINOID
CL2001032128AAother1e-050.99999 other
CL2001032129AAother01 other
CL2001032130AA (testset)other01 other
CL2001032132AA (testset)other1e-050.99999 other
CL2001032134AAother01 other
CL2001032135AAother01 other
CL2001032136AAother01 other
CL2001032138AAother01 other
CL2001032141AAother0.000160.99984 other
CL2001032142AA (testset)other0.000850.99915 other
CL2001032144AAother01 other
CL2001032145AA (testset)CARCINOID10 CARCINOID
CL2001032147AAother2e-050.99998 other
CL2001032149AAother01 other
CL2001032151AACARCINOID10 CARCINOID
CL2001032152AA (testset)CARCINOID10 CARCINOID
CL2001032153AAother7e-050.99993 other
CL2001032155AA (testset)other01 other
CL2001032156AAother01 other
CL2001032202AA (testset)other2e-050.99998 other
CL2001032206AAother01 other
CL2001032207AA (testset)other01 other
CL2001032209AA (testset)other9e-050.99991 other
CL2001032210AACARCINOID10 CARCINOID
CL2001032211AAother01 other
CL2001032212AA (testset)other2e-050.99998 other
CL2001032213AA (testset)other01 other
CL2001032214AAother01 other
CL2001032217AA (testset)other0.008330.99167 other
CL2001032218AA (testset)other1e-050.99999 other
CL2001032219AA (testset)CARCINOID0.999991e-05 CARCINOID
CL2001032220AAother01 other
CL2001032222AA (testset)other01 other
CL2001032229AA (testset)other1e-050.99999 other
CL2001032231AAother01 other
CL2001032232AAother0.000110.99989 other
CL2001032233AAother01 other
CL2001032238AACARCINOID0.998950.00105 CARCINOID
CL2001032239AAother01 other
CL2001032240AAother01 other
CL2001032241AA (testset)other01 other
CL2001032242AAother01 other
CL2001032243AA (testset)other3e-050.99997 other
CL2001032248AAother01 other
CL2001032249AAother01 other
CL2001032252AAother01 other
CL2001032254AA (testset)other01 other
CL2001032255AAother01 other
CL2001032256AA (testset)other01 other
CL2001032259AAother01 other
CL2001032260AAother0.080570.91943 other
CL2001032301AAother01 other
CL2001032304AA (testset)other1e-050.99999 other
CL2001032305AA (testset)other2e-050.99998 other
CL2001032306AAother01 other
CL2001032307AAother01 other
CL2001032308AAother01 other
CL2001032309AAother01 other
CL2001032310AAother5e-050.99995 other
CL2001032311AAother01 other
CL2001032312AAother01 other
CL2001032313AAother4e-050.99996 other
CL2001032314AAother01 other
CL2001032316AA (testset)other01 other
CL2001032601AAother01 other
CL2001032602AAother2e-050.99998 other
CL2001032604AAother6e-050.99994 other
CL2001032607AACARCINOID10 CARCINOID
CL2001032608AAother2e-050.99998 other
CL2001032610AA (testset)other01 other
CL2001032612AAother1e-050.99999 other
CL2001032613AA (testset)other01 other
CL2001032614AA (testset)other2e-050.99998 other
CL2001032616AAother0.000630.99937 other
CL2001032617AA (testset)other1e-050.99999 other
CL2001032620AA (testset)other01 other
CL2001032625AAother0.122190.87781 other
CL2001032627AA (testset)other1e-050.99999 other
CL2001032628AAother01 other
CL2001032629AACARCINOID10 CARCINOID
CL2001032630AACARCINOID10 CARCINOID
CL2001032632AAother0.000780.99922 other
CL2001032638AA (testset)other5e-040.9995 other
CL2001032640AAother0.000130.99987 other
CL2001032643AAother01 other
CL2001032644AA (testset)other01 other
CL2001032647AAother01 other
CL2001032701AAother01 other
CL2001032702AA (testset)other01 other
CL2001032703AAother01 other
CL2001032704AA (testset)other01 other
CL2001032706AAother01 other
CL2001032709AAother01 other
CL2001032716AAother6e-050.99994 other
CL2001032717AA (testset)other01 other
CL2001032718AAother01 other
CL2001032719AA (testset)other01 other
CL2001032720AAother0.005390.99461 other
CL2001032722AACARCINOID10 CARCINOID
CL2001032724AAother01 other
CL2001032725AA (testset)other0.000280.99972 other
CL2001032727AAother01 other
CL2001032729AA (testset)other01 other
CL2001032730AAother01 other
CL2001032732AA (testset)other1e-050.99999 other
CL2001032733AAother2e-050.99998 other
CL2001032738AAother01 other
CL2001032742AAother0.000140.99986 other
CL2001032746AAother01 other
CL2001032747AAother01 other
CL2001032833AAother0.013610.98639 other
CL2001032836AAother01 other
CL2001032838AAother01 other
CL2001032839AAother01 other
CL2001032841AAother1e-040.9999 other
CL2001032842AA (testset)other9e-050.99991 other
CL2001032843AA (testset)other01 other
CL2001032845AA (testset)other1e-050.99999 other
CL2001032846AAother01 other
CL2001032847AACARCINOID10 CARCINOID
CL2001032848AA (testset)other01 other
CL2001032850AACARCINOID10 CARCINOID
CL2001032853AA (testset)other01 other
CL2001032854AACARCINOID0.998360.00164 CARCINOID
CL2001032856AAother1e-050.99999 other
CL2001032857AA (testset)other1e-050.99999 other
CL2001032860AACARCINOID10 CARCINOID
CL2001040305AAother2e-050.99998 other
CL2001040306AAother01 other
CL2001041708AAother01 other
CL2001041711AA (testset)other01 other
CL2001041716AAother01 other
CL2001042501AA (testset)CARCINOID10 CARCINOID
CL2001042505AAother0.000150.99985 other
CL2001042506AAother01 other

 


Generated by StAM on Tue Sep 7 17:21:11 2004