GO:0007169


GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway
(annotated genes)

Biological
Process

Parent node

This leaf node contains 84 genes

The following 52 of these are used in classification:

 SymbolGenenameADENO scoreNORMAL score
1319_atDDR2 discoidin domain receptor family, member 2-0.08830.7222
32787_atERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.0859-0.7021
1146_atCD4 CD4 antigen (p55)-0.07260.5938
1585_atERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.0709-0.5797
36643_atDDR1 discoidin domain receptor family, member 10.0695-0.5682
2089_s_atERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.0637-0.5211
213_atROR1 receptor tyrosine kinase-like orphan receptor 1-0.06340.5181
33218_atERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.0567-0.4633
160022_atCSF1R colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog-0.05650.4622
1007_s_atDDR1 discoidin domain receptor family, member 10.056-0.4576
2088_s_atEPHB2 EphB20.055-0.4497
36042_atNTRK2 neurotrophic tyrosine kinase, receptor, type 2-0.05030.4109
1954_atKDR kinase insert domain receptor (a type III receptor tyrosine kinase)-0.04690.3836
1802_s_atERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.0465-0.3801
39930_atEPHB6 EphB6-0.04490.3669
1438_atEPHB3 EphB30.0425-0.3473
1731_atPDGFRA platelet-derived growth factor receptor, alpha polypeptide-0.03990.3261
41678_atEPHB2 EphB20.0368-0.3009
34433_atDOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)-0.03490.2854
33182_atNTRK2 neurotrophic tyrosine kinase, receptor, type 2-0.03340.273
39319_atLCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)-0.03330.2724
35517_atCD4 CD4 antigen (p55)-0.03330.2724
816_g_atDOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)-0.03240.2653
1723_g_atERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.032-0.2619
1901_s_atERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.0317-0.259
32401_atNRTN neurturin0.0315-0.2574
39309_atBDKRB2 bradykinin receptor B2-0.0290.2373
1963_atFLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)-0.02780.2273
1355_g_atNTRK2 neurotrophic tyrosine kinase, receptor, type 2-0.02750.2245
1742_atERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.0273-0.2232
40699_atCD8A CD8 antigen, alpha polypeptide (p32)-0.02540.208
1059_atNTRK3 neurotrophic tyrosine kinase, receptor, type 3-0.02190.1788
33769_atMPZL1 myelin protein zero-like 10.0205-0.1675
902_atEPHB2 EphB20.0179-0.1462
38870_atGFRA2 GDNF family receptor alpha 2-0.01720.1408
37363_atMTSS1 metastasis suppressor 1-0.01460.1196
1606_atEPHA4 EphA40.0138-0.1124
1605_g_atEPHA5 EphA5-0.01230.1009
1108_s_atEPHA1 EphA10.0123-0.1006
491_atPTPRG protein tyrosine phosphatase, receptor type, G-0.00830.0675
39596_atNTRK3 neurotrophic tyrosine kinase, receptor, type 3-0.00820.0668
38280_s_atNTRK2 neurotrophic tyrosine kinase, receptor, type 2-0.0080.0658
1432_s_atLTK leukocyte tyrosine kinase-0.00710.0578
39227_atPTPRT protein tyrosine phosphatase, receptor type, T-0.00710.0578
815_atDOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)-0.00560.0456
34564_atEPHA5 EphA50.0053-0.0433
32888_atLTK leukocyte tyrosine kinase-0.00490.0399
1545_g_atFLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)-0.00480.0394
39239_atCD8B1 CD8 antigen, beta polypeptide 1 (p37)-0.00440.0361
690_s_atKDR kinase insert domain receptor (a type III receptor tyrosine kinase)-0.00410.0336
1485_atEPHA7 EphA7-9e-040.0072
1572_s_atINSR insulin receptor-6e-040.0052

Performance on training data

 SensitivitySpecificity
ADENO0.920861
NORMAL10.92086

Performance on test data

 SensitivitySpecificity
ADENO0.920861
NORMAL10.92086

Predictions

 ClassADENONORMALPredictionn
CL2001031608AA (testset)ADENO0.631870.36813 ADENO
CL2001031611AA (testset)ADENO0.950390.04961 ADENO
CL2001031612AA (testset)ADENO10 ADENO
CL2001031613AA (testset)ADENO0.342710.65729 NORMAL
CL2001031615AA (testset)ADENO0.999890.00011 ADENO
CL2001031616AA (testset)ADENO0.947570.05243 ADENO
CL2001031618AA (testset)ADENO0.98890.0111 ADENO
CL2001031622AA (testset)ADENO0.997610.00239 ADENO
CL2001031625AA (testset)ADENO0.999870.00013 ADENO
CL2001031627AA (testset)ADENO0.917210.08279 ADENO
CL2001031628AA (testset)ADENO0.9920.008 ADENO
CL2001031629AA (testset)ADENO0.999982e-05 ADENO
CL2001031630AA (testset)ADENO0.999880.00012 ADENO
CL2001031631AA (testset)ADENO0.999982e-05 ADENO
CL2001031632AA (testset)ADENO0.987480.01252 ADENO
CL2001031634AA (testset)ADENO0.999860.00014 ADENO
CL2001031635AA (testset)ADENO0.300780.69922 NORMAL
CL2001031636AA (testset)ADENO0.234220.76578 NORMAL
CL2001032002AA (testset)ADENO0.999640.00036 ADENO
CL2001032005AA (testset)ADENO0.998240.00176 ADENO
CL2001032008AA (testset)ADENO10 ADENO
CL2001032009AA (testset)ADENO0.996530.00347 ADENO
CL2001032011AA (testset)ADENO0.916650.08335 ADENO
CL2001032012AA (testset)ADENO0.805460.19454 ADENO
CL2001032013AA (testset)ADENO0.815330.18467 ADENO
CL2001032015AA (testset)ADENO0.149050.85095 NORMAL
CL2001032016AA (testset)ADENO0.999820.00018 ADENO
CL2001032019AA (testset)ADENO0.999530.00047 ADENO
CL2001032020AA (testset)ADENO0.99450.0055 ADENO
CL2001032025AA (testset)ADENO0.999780.00022 ADENO
CL2001032026AA (testset)ADENO0.950230.04977 ADENO
CL2001032027AA (testset)ADENO0.998070.00193 ADENO
CL2001032030AA (testset)ADENO0.982130.01787 ADENO
CL2001032031AA (testset)ADENO0.997540.00246 ADENO
CL2001032032AA (testset)ADENO0.963930.03607 ADENO
CL2001032034AA (testset)ADENO0.989010.01099 ADENO
CL2001032036AA (testset)ADENO0.010990.98901 NORMAL
CL2001032103AA (testset)ADENO0.899930.10007 ADENO
CL2001032104AA (testset)ADENO10 ADENO
CL2001032105AA (testset)ADENO0.999991e-05 ADENO
CL2001032107AA (testset)ADENO0.999830.00017 ADENO
CL2001032108AA (testset)ADENO0.982760.01724 ADENO
CL2001032109AA (testset)ADENO0.856690.14331 ADENO
CL2001032110AA (testset)ADENO0.792310.20769 ADENO
CL2001032111AA (testset)ADENO0.999090.00091 ADENO
CL2001032113AA (testset)ADENO0.999890.00011 ADENO
CL2001032114AA (testset)ADENO0.284060.71594 NORMAL
CL2001032115AA (testset)ADENO0.988610.01139 ADENO
CL2001032116AA (testset)ADENO0.999928e-05 ADENO
CL2001032117AA (testset)ADENO10 ADENO
CL2001032125AA (testset)ADENO0.789750.21025 ADENO
CL2001032130AA (testset)ADENO0.975160.02484 ADENO
CL2001032132AA (testset)ADENO0.999870.00013 ADENO
CL2001032134AA (testset)ADENO0.99480.0052 ADENO
CL2001032135AA (testset)ADENO0.99991e-04 ADENO
CL2001032136AA (testset)ADENO0.999840.00016 ADENO
CL2001032138AA (testset)ADENO0.998940.00106 ADENO
CL2001032141AA (testset)ADENO0.999260.00074 ADENO
CL2001032142AA (testset)ADENO0.996440.00356 ADENO
CL2001032149AA (testset)ADENO0.970030.02997 ADENO
CL2001032155AA (testset)ADENO0.60110.3989 ADENO
CL2001032156AA (testset)ADENO0.86330.1367 ADENO
CL2001032211AA (testset)ADENO0.990610.00939 ADENO
CL2001032212AA (testset)ADENO0.999140.00086 ADENO
CL2001032213AA (testset)ADENO0.001020.99898 NORMAL
CL2001032214AA (testset)ADENO0.966830.03317 ADENO
CL2001032229AA (testset)ADENO0.989940.01006 ADENO
CL2001032232AA (testset)ADENO10 ADENO
CL2001032233AA (testset)ADENO0.967740.03226 ADENO
CL2001032241AA (testset)ADENO0.691310.30869 ADENO
CL2001032242AA (testset)ADENO0.998980.00102 ADENO
CL2001032243AA (testset)ADENO0.99991e-04 ADENO
CL2001032248AA (testset)ADENO0.999964e-05 ADENO
CL2001032249AA (testset)ADENO0.999170.00083 ADENO
CL2001032252AA (testset)ADENO0.999490.00051 ADENO
CL2001032254AA (testset)ADENO0.894070.10593 ADENO
CL2001032255AA (testset)ADENO0.99780.0022 ADENO
CL2001032259AA (testset)ADENO0.230610.76939 NORMAL
CL2001032301AA (testset)ADENO0.990730.00927 ADENO
CL2001032306AA (testset)ADENO0.988380.01162 ADENO
CL2001032307AA (testset)ADENO0.987610.01239 ADENO
CL2001032308AA (testset)ADENO0.944850.05515 ADENO
CL2001032309AA (testset)ADENO0.999650.00035 ADENO
CL2001032310AA (testset)ADENO10 ADENO
CL2001032311AA (testset)ADENO0.999520.00048 ADENO
CL2001032312AA (testset)ADENO0.993790.00621 ADENO
CL2001032313AA (testset)ADENO0.944210.05579 ADENO
CL2001032314AA (testset)ADENO0.951790.04821 ADENO
CL2001032316AA (testset)ADENO0.982030.01797 ADENO
CL2001032601AA (testset)ADENO0.999690.00031 ADENO
CL2001032602AA (testset)ADENO0.999991e-05 ADENO
CL2001032604AA (testset)ADENO0.999430.00057 ADENO
CL2001032610AA (testset)ADENO0.999740.00026 ADENO
CL2001032612AA (testset)ADENO0.993790.00621 ADENO
CL2001032613AA (testset)ADENO0.996510.00349 ADENO
CL2001032614AA (testset)ADENO0.989140.01086 ADENO
CL2001032616AA (testset)ADENO0.998070.00193 ADENO
CL2001032617AA (testset)ADENO0.999955e-05 ADENO
CL2001032620AA (testset)ADENO0.996640.00336 ADENO
CL2001032625AA (testset)ADENO0.998560.00144 ADENO
CL2001032628AA (testset)ADENO0.985090.01491 ADENO
CL2001032638AA (testset)ADENO10 ADENO
CL2001032640AA (testset)ADENO0.999991e-05 ADENO
CL2001032643AA (testset)ADENO0.829450.17055 ADENO
CL2001032647AA (testset)ADENO0.949510.05049 ADENO
CL2001032701AA (testset)ADENO0.999470.00053 ADENO
CL2001032702AA (testset)ADENO0.999250.00075 ADENO
CL2001032703AA (testset)ADENO0.41350.5865 NORMAL
CL2001032704AA (testset)ADENO0.93560.0644 ADENO
CL2001032706AA (testset)ADENO0.999270.00073 ADENO
CL2001032709AA (testset)ADENO0.985810.01419 ADENO
CL2001032716AA (testset)ADENO0.999964e-05 ADENO
CL2001032717AA (testset)ADENO0.999290.00071 ADENO
CL2001032729AA (testset)ADENO0.942610.05739 ADENO
CL2001032730AA (testset)ADENO0.998040.00196 ADENO
CL2001032733AA (testset)ADENO0.999780.00022 ADENO
CL2001032738AA (testset)ADENO0.841840.15816 ADENO
CL2001032742AA (testset)ADENO10 ADENO
CL2001032746AA (testset)ADENO0.979730.02027 ADENO
CL2001032747AA (testset)ADENO0.999450.00055 ADENO
CL2001032833AA (testset)ADENO0.999870.00013 ADENO
CL2001032836AA (testset)ADENO0.999860.00014 ADENO
CL2001032838AA (testset)ADENO10 ADENO
CL2001032839AA (testset)ADENO0.997430.00257 ADENO
CL2001032841AA (testset)ADENO0.989350.01065 ADENO
CL2001032842AA (testset)ADENO0.99890.0011 ADENO
CL2001032843AA (testset)ADENO0.999740.00026 ADENO
CL2001032845AA (testset)ADENO0.594550.40545 ADENO
CL2001032846AA (testset)ADENO0.999973e-05 ADENO
CL2001032848AA (testset)ADENO0.009330.99067 NORMAL
CL2001032856AA (testset)ADENO0.636470.36353 ADENO
CL2001032857AA (testset)ADENO0.999770.00023 ADENO
CL2001040305AA (testset)ADENO0.999919e-05 ADENO
CL2001040306AA (testset)ADENO0.996950.00305 ADENO
CL2001041708AA (testset)ADENO0.996490.00351 ADENO
CL2001041711AA (testset)ADENO0.999290.00071 ADENO
CL2001041716AA (testset)ADENO0.983960.01604 ADENO
CL2001042505AA (testset)ADENO10 ADENO
CL2001042506AA (testset)ADENO0.095610.90439 NORMAL
CL2001032010AA (testset)NORMAL0.01380.9862 NORMAL
CL2001032041AA (testset)NORMAL0.001840.99816 NORMAL
CL2001032043AA (testset)NORMAL0.031330.96867 NORMAL
CL2001032045AA (testset)NORMAL0.005490.99451 NORMAL
CL2001032046AA (testset)NORMAL0.092520.90748 NORMAL
CL2001032102AA (testset)NORMAL0.057240.94276 NORMAL
CL2001032128AA (testset)NORMAL0.006280.99372 NORMAL
CL2001032147AA (testset)NORMAL0.016880.98312 NORMAL
CL2001032202AA (testset)NORMAL0.060660.93934 NORMAL
CL2001032206AA (testset)NORMAL0.002170.99783 NORMAL
CL2001032220AA (testset)NORMAL0.154480.84552 NORMAL
CL2001032256AA (testset)NORMAL0.015060.98494 NORMAL
CL2001032304AA (testset)NORMAL0.009830.99017 NORMAL
CL2001032718AA (testset)NORMAL0.00760.9924 NORMAL
CL2001032724AA (testset)NORMAL0.467780.53222 NORMAL
CL2001032725AA (testset)NORMAL0.350970.64903 NORMAL
CL2001032727AA (testset)NORMAL0.179310.82069 NORMAL

 


Generated by StAM on Tue Sep 7 18:10:42 2004