GO:0006917


GO:0006917

induction of apoptosis
(annotated genes)

Biological
Process

Parent node

This leaf node contains 102 genes

The following 90 of these are used in classification:

 SymbolGenenameADENO scoreNORMAL score
34740_atFOXO3A forkhead box O3A-0.11390.931
33390_atSTK17B serine/threonine kinase 17b (apoptosis-inducing)-0.09690.7926
924_s_atPPP2CB protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform-0.09050.74
36943_r_atPLAGL1 pleiomorphic adenoma gene-like 1-0.08550.6991
1715_atTNFSF10 tumor necrosis factor (ligand) superfamily, member 10-0.08130.6645
39436_atBNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like-0.07880.6439
39588_atTNFSF12 tumor necrosis factor (ligand) superfamily, member 12-0.07640.6245
34912_atDAPK2 death-associated protein kinase 2-0.07590.6209
33562_g_atCOL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)-0.07080.5786
38754_atP8 p8 protein (candidate of metastasis 1)-0.07040.5758
36423_atP8 p8 protein (candidate of metastasis 1)-0.06870.5619
33561_atCOL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)-0.0620.5067
37127_atNALP1 NACHT, leucine rich repeat and PYD containing 1-0.05610.4585
37643_atTNFRSF6 tumor necrosis factor receptor superfamily, member 6-0.05580.456
35662_atCASP6 caspase 6, apoptosis-related cysteine protease0.0528-0.432
33852_atTIA1 TIA1 cytotoxic granule-associated RNA binding protein0.0485-0.3964
38824_atHTATIP2 HIV-1 Tat interactive protein 2, 30kDa0.0439-0.3587
1441_s_atTNFRSF6 tumor necrosis factor receptor superfamily, member 6-0.04330.3541
33598_r_atCIAS1 cold autoinflammatory syndrome 1-0.04250.3472
36944_f_atPLAGL1 pleiomorphic adenoma gene-like 1-0.04250.3472
608_atAPOE apolipoprotein E0.0419-0.3429
38050_atBCLAF1 BCL2-associated transcription factor 1-0.04080.3338
41763_g_atTIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 10.0387-0.3163
2011_s_atBIK BCL2-interacting killer (apoptosis-inducing)0.0362-0.2957
846_s_atBAK1 BCL2-antagonist/killer 10.0341-0.279
1687_s_atBAK1 BCL2-antagonist/killer 10.0331-0.2708
1729_atTRADD TNFRSF1A-associated via death domain0.0331-0.2706
195_s_atCASP4 caspase 4, apoptosis-related cysteine protease-0.03110.2543
38544_atINHA inhibin, alpha0.031-0.2533
37057_s_atTRAF3 TNF receptor-associated factor 30.0308-0.2522
34625_atLALBA lactalbumin, alpha--0.03050.2493
31742_atTNFSF14 tumor necrosis factor (ligand) superfamily, member 14-0.03040.2489
1440_s_atTNFRSF6 tumor necrosis factor receptor superfamily, member 6-0.02980.244
235_atS100B S100 calcium binding protein, beta (neural)0.0291-0.2378
36143_atCASP3 caspase 3, apoptosis-related cysteine protease0.0289-0.2365
38578_atTNFRSF7 tumor necrosis factor receptor superfamily, member 70.0287-0.2349
31540_atTNFRSF9 tumor necrosis factor receptor superfamily, member 90.0285-0.2328
237_s_atPPP2CA protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform-0.0270.2211
1808_s_atTNFRSF6 tumor necrosis factor receptor superfamily, member 60.0268-0.2188
2067_f_atBAX BCL2-associated X protein0.0267-0.2186
31611_s_atBCL2L11 BCL2-like 11 (apoptosis facilitator)0.0262-0.214
255_s_atINHA inhibin, alpha0.0236-0.1931
37430_atALOX15B arachidonate 15-lipoxygenase, second type-0.02080.1705
37767_atHD huntingtin (Huntington disease)-0.02010.1646
197_atNME3 non-metastatic cells 3, protein expressed in0.0201-0.1644
36393_atDPF1 D4, zinc and double PHD fingers family 10.02-0.1637
33903_atDAPK3 death-associated protein kinase 3-0.01940.1586
38083_atNOTCH2 Notch homolog 2 (Drosophila)0.0193-0.1582
41762_atTIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 10.019-0.1553
1770_atIFNA2 interferon, alpha 2-0.01790.1466
1791_s_atIFNA2 interferon, alpha 2-0.01770.1444
36278_atMAP3K10 mitogen-activated protein kinase kinase kinase 100.0176-0.1442
35346_atFEM1B fem-1 homolog b (C. elegans)-0.0170.1389
35588_atZNF443 zinc finger protein 443-0.01580.1289
32891_atPRKCE protein kinase C, epsilon-0.01490.1221
259_s_atLTA lymphotoxin alpha (TNF superfamily, member 1)0.0138-0.1125
39999_atCASP10 caspase 10, apoptosis-related cysteine protease-0.01360.1109
32890_atDCC deleted in colorectal carcinoma-0.01320.1083
41429_atPPP2R1B protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform-0.01180.0965
1093_atPPP2R1B protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform0.0116-0.0952
31383_atCASP13 caspase 13, apoptosis-related cysteine protease-0.01130.0922
2066_atBAX BCL2-associated X protein-0.00960.0789
34011_atHRK harakiri, BCL2 interacting protein (contains only BH3 domain)0.009-0.0739
38822_atSTK17A serine/threonine kinase 17a (apoptosis-inducing)0.0088-0.0723
33563_s_atCOL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)-0.00880.0717
37644_s_atTNFRSF6 tumor necrosis factor receptor superfamily, member 6-0.00860.0703
40738_atCD2 CD2 antigen (p50), sheep red blood cell receptor-0.00830.0679
36296_atLTA lymphotoxin alpha (TNF superfamily, member 1)0.0083-0.0676
389_s_atTNFRSF6 tumor necrosis factor receptor superfamily, member 60.0075-0.0614
38823_s_atSTK17A serine/threonine kinase 17a (apoptosis-inducing)0.0072-0.0589
1326_atCASP10 caspase 10, apoptosis-related cysteine protease-0.00710.0577
1858_atTNFSF6 tumor necrosis factor (ligand) superfamily, member 6-0.00690.0563
1766_g_atCASP10 caspase 10, apoptosis-related cysteine protease-0.00660.0538
1203_atINHBA inhibin, beta A (activin A, activin AB alpha polypeptide)-0.00540.0439
1765_atCASP10 caspase 10, apoptosis-related cysteine protease-0.00450.037
38097_atEI24 etoposide induced 2.4 mRNA-0.00430.0354
37524_atSTK17B serine/threonine kinase 17b (apoptosis-inducing)-0.00420.0347
36843_atSIPA1 signal-induced proliferation-associated gene 10.0041-0.0334
417_atPRKCE protein kinase C, epsilon-0.00340.0281
33047_atBCL2L11 BCL2-like 11 (apoptosis facilitator)0.0031-0.0255
198_g_atNME3 non-metastatic cells 3, protein expressed in0.003-0.0248
41761_atTIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1-0.00290.0238
1094_g_atPPP2R1B protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform0.0024-0.0195
38040_atSMNDC1 survival motor neuron domain containing 10.0022-0.0183
2065_s_atBAX BCL2-associated X protein0.0022-0.0179
33166_atTRADD TNFRSF1A-associated via death domain-0.00220.0178
40494_atDEDD death effector domain containing-0.00180.0148
40357_atINHBA inhibin, beta A (activin A, activin AB alpha polypeptide)-0.00180.0144
33012_atTNFSF8 tumor necrosis factor (ligand) superfamily, member 8-9e-040.0077
976_s_atMAPK1 mitogen-activated protein kinase 1-2e-040.0015

Performance on training data

 SensitivitySpecificity
ADENO0.971220.94118
NORMAL0.941180.97122

Performance on test data

 SensitivitySpecificity
ADENO0.971220.94118
NORMAL0.941180.97122

Predictions

 ClassADENONORMALPredictionn
CL2001031608AA (testset)ADENO0.992690.00731 ADENO
CL2001031611AA (testset)ADENO0.999946e-05 ADENO
CL2001031612AA (testset)ADENO0.997160.00284 ADENO
CL2001031613AA (testset)ADENO0.045420.95458 NORMAL
CL2001031615AA (testset)ADENO0.999937e-05 ADENO
CL2001031616AA (testset)ADENO0.999140.00086 ADENO
CL2001031618AA (testset)ADENO0.999870.00013 ADENO
CL2001031622AA (testset)ADENO0.999040.00096 ADENO
CL2001031625AA (testset)ADENO0.999928e-05 ADENO
CL2001031627AA (testset)ADENO0.999730.00027 ADENO
CL2001031628AA (testset)ADENO0.999580.00042 ADENO
CL2001031629AA (testset)ADENO0.999790.00021 ADENO
CL2001031630AA (testset)ADENO10 ADENO
CL2001031631AA (testset)ADENO0.999680.00032 ADENO
CL2001031632AA (testset)ADENO0.995840.00416 ADENO
CL2001031634AA (testset)ADENO0.999540.00046 ADENO
CL2001031635AA (testset)ADENO0.999560.00044 ADENO
CL2001031636AA (testset)ADENO0.997470.00253 ADENO
CL2001032002AA (testset)ADENO0.999890.00011 ADENO
CL2001032005AA (testset)ADENO10 ADENO
CL2001032008AA (testset)ADENO0.99991e-04 ADENO
CL2001032009AA (testset)ADENO0.999780.00022 ADENO
CL2001032011AA (testset)ADENO0.948180.05182 ADENO
CL2001032012AA (testset)ADENO0.547010.45299 ADENO
CL2001032013AA (testset)ADENO0.939450.06055 ADENO
CL2001032015AA (testset)ADENO0.994860.00514 ADENO
CL2001032016AA (testset)ADENO0.999991e-05 ADENO
CL2001032019AA (testset)ADENO0.999870.00013 ADENO
CL2001032020AA (testset)ADENO0.999610.00039 ADENO
CL2001032025AA (testset)ADENO0.999250.00075 ADENO
CL2001032026AA (testset)ADENO0.997780.00222 ADENO
CL2001032027AA (testset)ADENO0.994650.00535 ADENO
CL2001032030AA (testset)ADENO0.999982e-05 ADENO
CL2001032031AA (testset)ADENO0.999390.00061 ADENO
CL2001032032AA (testset)ADENO0.995220.00478 ADENO
CL2001032034AA (testset)ADENO0.151350.84865 NORMAL
CL2001032036AA (testset)ADENO0.997050.00295 ADENO
CL2001032103AA (testset)ADENO0.999946e-05 ADENO
CL2001032104AA (testset)ADENO0.99991e-04 ADENO
CL2001032105AA (testset)ADENO10 ADENO
CL2001032107AA (testset)ADENO0.999991e-05 ADENO
CL2001032108AA (testset)ADENO0.999470.00053 ADENO
CL2001032109AA (testset)ADENO0.665240.33476 ADENO
CL2001032110AA (testset)ADENO0.95170.0483 ADENO
CL2001032111AA (testset)ADENO0.97580.0242 ADENO
CL2001032113AA (testset)ADENO10 ADENO
CL2001032114AA (testset)ADENO0.996030.00397 ADENO
CL2001032115AA (testset)ADENO0.997870.00213 ADENO
CL2001032116AA (testset)ADENO0.999982e-05 ADENO
CL2001032117AA (testset)ADENO0.999570.00043 ADENO
CL2001032125AA (testset)ADENO10 ADENO
CL2001032130AA (testset)ADENO0.996330.00367 ADENO
CL2001032132AA (testset)ADENO0.999973e-05 ADENO
CL2001032134AA (testset)ADENO0.999070.00093 ADENO
CL2001032135AA (testset)ADENO0.991580.00842 ADENO
CL2001032136AA (testset)ADENO0.997180.00282 ADENO
CL2001032138AA (testset)ADENO0.992950.00705 ADENO
CL2001032141AA (testset)ADENO0.999973e-05 ADENO
CL2001032142AA (testset)ADENO0.999710.00029 ADENO
CL2001032149AA (testset)ADENO0.9630.037 ADENO
CL2001032155AA (testset)ADENO0.015670.98433 NORMAL
CL2001032156AA (testset)ADENO0.943420.05658 ADENO
CL2001032211AA (testset)ADENO10 ADENO
CL2001032212AA (testset)ADENO0.999880.00012 ADENO
CL2001032213AA (testset)ADENO0.926290.07371 ADENO
CL2001032214AA (testset)ADENO0.920040.07996 ADENO
CL2001032229AA (testset)ADENO0.999982e-05 ADENO
CL2001032232AA (testset)ADENO0.99370.0063 ADENO
CL2001032233AA (testset)ADENO0.999919e-05 ADENO
CL2001032241AA (testset)ADENO0.953660.04634 ADENO
CL2001032242AA (testset)ADENO0.999740.00026 ADENO
CL2001032243AA (testset)ADENO0.742530.25747 ADENO
CL2001032248AA (testset)ADENO0.998250.00175 ADENO
CL2001032249AA (testset)ADENO0.999991e-05 ADENO
CL2001032252AA (testset)ADENO0.998150.00185 ADENO
CL2001032254AA (testset)ADENO0.994930.00507 ADENO
CL2001032255AA (testset)ADENO0.999946e-05 ADENO
CL2001032259AA (testset)ADENO0.990050.00995 ADENO
CL2001032301AA (testset)ADENO0.99973e-04 ADENO
CL2001032306AA (testset)ADENO0.999982e-05 ADENO
CL2001032307AA (testset)ADENO0.969730.03027 ADENO
CL2001032308AA (testset)ADENO0.999946e-05 ADENO
CL2001032309AA (testset)ADENO0.996430.00357 ADENO
CL2001032310AA (testset)ADENO10 ADENO
CL2001032311AA (testset)ADENO0.999180.00082 ADENO
CL2001032312AA (testset)ADENO0.999991e-05 ADENO
CL2001032313AA (testset)ADENO0.999964e-05 ADENO
CL2001032314AA (testset)ADENO0.999890.00011 ADENO
CL2001032316AA (testset)ADENO0.999919e-05 ADENO
CL2001032601AA (testset)ADENO0.999870.00013 ADENO
CL2001032602AA (testset)ADENO10 ADENO
CL2001032604AA (testset)ADENO0.999770.00023 ADENO
CL2001032610AA (testset)ADENO0.999919e-05 ADENO
CL2001032612AA (testset)ADENO0.999140.00086 ADENO
CL2001032613AA (testset)ADENO0.999620.00038 ADENO
CL2001032614AA (testset)ADENO10 ADENO
CL2001032616AA (testset)ADENO0.999770.00023 ADENO
CL2001032617AA (testset)ADENO0.999973e-05 ADENO
CL2001032620AA (testset)ADENO0.999270.00073 ADENO
CL2001032625AA (testset)ADENO0.999973e-05 ADENO
CL2001032628AA (testset)ADENO0.999840.00016 ADENO
CL2001032638AA (testset)ADENO0.999770.00023 ADENO
CL2001032640AA (testset)ADENO0.999982e-05 ADENO
CL2001032643AA (testset)ADENO0.999250.00075 ADENO
CL2001032647AA (testset)ADENO0.989370.01063 ADENO
CL2001032701AA (testset)ADENO10 ADENO
CL2001032702AA (testset)ADENO0.998540.00146 ADENO
CL2001032703AA (testset)ADENO0.999820.00018 ADENO
CL2001032704AA (testset)ADENO0.972220.02778 ADENO
CL2001032706AA (testset)ADENO0.99880.0012 ADENO
CL2001032709AA (testset)ADENO0.999880.00012 ADENO
CL2001032716AA (testset)ADENO0.99780.0022 ADENO
CL2001032717AA (testset)ADENO0.999510.00049 ADENO
CL2001032729AA (testset)ADENO0.999610.00039 ADENO
CL2001032730AA (testset)ADENO0.999991e-05 ADENO
CL2001032733AA (testset)ADENO0.999530.00047 ADENO
CL2001032738AA (testset)ADENO0.999928e-05 ADENO
CL2001032742AA (testset)ADENO0.997550.00245 ADENO
CL2001032746AA (testset)ADENO0.999720.00028 ADENO
CL2001032747AA (testset)ADENO0.999919e-05 ADENO
CL2001032833AA (testset)ADENO0.985850.01415 ADENO
CL2001032836AA (testset)ADENO0.99946e-04 ADENO
CL2001032838AA (testset)ADENO0.998930.00107 ADENO
CL2001032839AA (testset)ADENO0.999964e-05 ADENO
CL2001032841AA (testset)ADENO0.997810.00219 ADENO
CL2001032842AA (testset)ADENO10 ADENO
CL2001032843AA (testset)ADENO10 ADENO
CL2001032845AA (testset)ADENO0.999820.00018 ADENO
CL2001032846AA (testset)ADENO0.999780.00022 ADENO
CL2001032848AA (testset)ADENO0.003850.99615 NORMAL
CL2001032856AA (testset)ADENO0.999660.00034 ADENO
CL2001032857AA (testset)ADENO0.99420.0058 ADENO
CL2001040305AA (testset)ADENO10 ADENO
CL2001040306AA (testset)ADENO0.999982e-05 ADENO
CL2001041708AA (testset)ADENO0.999720.00028 ADENO
CL2001041711AA (testset)ADENO0.999740.00026 ADENO
CL2001041716AA (testset)ADENO0.863490.13651 ADENO
CL2001042505AA (testset)ADENO10 ADENO
CL2001042506AA (testset)ADENO0.992570.00743 ADENO
CL2001032010AA (testset)NORMAL0.281210.71879 NORMAL
CL2001032041AA (testset)NORMAL0.012230.98777 NORMAL
CL2001032043AA (testset)NORMAL0.000350.99965 NORMAL
CL2001032045AA (testset)NORMAL0.026720.97328 NORMAL
CL2001032046AA (testset)NORMAL0.01160.9884 NORMAL
CL2001032102AA (testset)NORMAL0.007710.99229 NORMAL
CL2001032128AA (testset)NORMAL0.003010.99699 NORMAL
CL2001032147AA (testset)NORMAL0.0080.992 NORMAL
CL2001032202AA (testset)NORMAL0.006680.99332 NORMAL
CL2001032206AA (testset)NORMAL0.044150.95585 NORMAL
CL2001032220AA (testset)NORMAL0.011150.98885 NORMAL
CL2001032256AA (testset)NORMAL0.816340.18366 ADENO
CL2001032304AA (testset)NORMAL0.234240.76576 NORMAL
CL2001032718AA (testset)NORMAL4e-050.99996 NORMAL
CL2001032724AA (testset)NORMAL0.269420.73058 NORMAL
CL2001032725AA (testset)NORMAL0.010340.98966 NORMAL
CL2001032727AA (testset)NORMAL0.016530.98347 NORMAL

 


Generated by StAM on Tue Sep 7 18:10:39 2004