GO:0006915


GO:0006915

apoptosis
(annotated genes)

Biological
Process

Parent node

This leaf node contains 200 genes

The following 170 of these are used in classification:

 SymbolGenenameADENO scoreNORMAL score
37028_atPPP1R15A protein phosphatase 1, regulatory (inhibitor) subunit 15A-0.17521.3577
37384_atPPM1F protein phosphatase 1F (PP2C domain containing)-0.1441.1157
37972_atDNASE1L3 deoxyribonuclease I-like 3-0.12330.9558
31888_s_atPHLDA2 pleckstrin homology-like domain, family A, member 20.1203-0.9324
35331_atCTNNAL1 catenin (cadherin-associated protein), alpha-like 1-0.11920.9238
35832_atSULF1 sulfatase 10.119-0.9223
33813_atTNFRSF1B tumor necrosis factor receptor superfamily, member 1B-0.11510.8923
37543_atARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6-0.11130.8627
33390_atSTK17B serine/threonine kinase 17b (apoptosis-inducing)-0.11070.8581
36275_atSEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A-0.11040.8556
1461_atNFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha-0.1090.8448
1583_atTNFRSF1B tumor necrosis factor receptor superfamily, member 1B-0.10690.8288
35633_atELMO1 engulfment and cell motility 1 (ced-12 homolog, C. elegans)-0.10560.8188
39691_atSH3GLB1 SH3-domain GRB2-like endophilin B1-0.10470.8116
595_atTNFAIP3 tumor necrosis factor, alpha-induced protein 3-0.10160.7876
40049_atDAPK1 death-associated protein kinase 1-0.10140.7862
35869_atLY86 lymphocyte antigen 86-0.10120.7839
34740_atFOXO3A forkhead box O3A-0.1010.7826
32060_atBNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2-0.08710.6748
37912_atTRAF4 TNF receptor-associated factor 40.0858-0.6651
39436_atBNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like-0.08320.6448
36199_atDAP death-associated protein0.08-0.62
1558_g_atPAK1 p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)0.0793-0.6149
33988_atTEGT testis enhanced gene transcript (BAX inhibitor 1)-0.0750.581
41193_atDUSP6 dual specificity phosphatase 6-0.07480.5794
35402_atTNFRSF21 tumor necrosis factor receptor superfamily, member 210.0741-0.5742
34912_atDAPK2 death-associated protein kinase 2-0.07330.5681
1715_atTNFSF10 tumor necrosis factor (ligand) superfamily, member 10-0.07170.5557
1356_atDAP3 death associated protein 30.0687-0.5327
32370_atGZMH granzyme H (cathepsin G-like 2, protein h-CCPX)-0.0680.5267
37569_atPDCD6 programmed cell death 60.0654-0.507
40237_atPHLDA2 pleckstrin homology-like domain, family A, member 20.0651-0.5046
1237_atIER3 immediate early response 30.0645-0.4998
35238_atTRAF5 TNF receptor-associated factor 50.0639-0.4954
1557_atPAK1 p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)0.0607-0.4705
39588_atTNFSF12 tumor necrosis factor (ligand) superfamily, member 12-0.06050.4691
32212_atPDCD8 programmed cell death 8 (apoptosis-inducing factor)0.0602-0.4666
33598_r_atCIAS1 cold autoinflammatory syndrome 1-0.05990.4639
33804_atPTK2B PTK2B protein tyrosine kinase 2 beta-0.05770.4475
36661_s_atCD14 CD14 antigen-0.05730.4438
1520_s_atIL1B interleukin 1, beta-0.05520.4277
33989_f_atTEGT testis enhanced gene transcript (BAX inhibitor 1)-0.05510.427
38114_atRAD21 RAD21 homolog (S. pombe)0.0541-0.4192
40621_atPAWR PRKC, apoptosis, WT1, regulator0.0526-0.408
39996_atCD5L CD5 antigen-like (scavenger receptor cysteine rich family)-0.05150.3988
40926_atBCAP31 B-cell receptor-associated protein 310.0511-0.3964
39509_atPDCD4 programmed cell death 4 (neoplastic transformation inhibitor)-0.05010.3882
33852_atTIA1 TIA1 cytotoxic granule-associated RNA binding protein0.049-0.38
34463_atDNASE1 deoxyribonuclease I0.049-0.3795
38578_atTNFRSF7 tumor necrosis factor receptor superfamily, member 70.0486-0.377
39402_atIL1B interleukin 1, beta-0.04810.3731
33884_s_atUBE4B ubiquitination factor E4B (UFD2 homolog, yeast)0.0476-0.369
973_atSGK serum/glucocorticoid regulated kinase-0.04710.3651
38010_atBNIP3 BCL2/adenovirus E1B 19kDa interacting protein 30.045-0.3491
33496_atAGTR2 angiotensin II receptor, type 2-0.04420.3424
33299_atCDC2L2 cell division cycle 2-like 20.0438-0.3397
38158_atESPL1 extra spindle poles like 1 (S. cerevisiae)0.0434-0.3364
41763_g_atTIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 10.0432-0.3348
32115_r_atADORA2A adenosine A2a receptor0.0431-0.3337
33357_atNCKAP1 NCK-associated protein 10.0428-0.3319
1729_atTRADD TNFRSF1A-associated via death domain0.0419-0.3248
36143_atCASP3 caspase 3, apoptosis-related cysteine protease0.0411-0.3181
35149_atTNFRSF5 tumor necrosis factor receptor superfamily, member 5-0.04050.3136
35662_atCASP6 caspase 6, apoptosis-related cysteine protease0.0394-0.3054
36463_atBAG5 BCL2-associated athanogene 5-0.03770.2924
33319_atAXIN1 axin 10.0377-0.2924
34930_atGPR65 G protein-coupled receptor 65-0.03760.2913
41848_f_atIL24 interleukin 240.0374-0.2895
794_atPTPN6 protein tyrosine phosphatase, non-receptor type 6-0.03670.2841
40696_atRIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1-0.03650.2828
36716_atADRA1A adrenergic, alpha-1A-, receptor-0.03480.2694
38742_s_atRAF1 v-raf-1 murine leukemia viral oncogene homolog 10.0344-0.2665
1974_s_atTP53 tumor protein p53 (Li-Fraumeni syndrome)0.034-0.2633
38804_atCSE1L CSE1 chromosome segregation 1-like (yeast)0.0322-0.2496
37137_atGZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)-0.0320.2482
33164_atTESK2 testis-specific kinase 2-0.03120.2416
39154_atGADD45G growth arrest and DNA-damage-inducible, gamma0.0299-0.232
1917_atRAF1 v-raf-1 murine leukemia viral oncogene homolog 1-0.02990.2314
1852_atTNF tumor necrosis factor (TNF superfamily, member 2)-0.02830.2194
1328_atTRAF5 TNF receptor-associated factor 50.0281-0.218
33085_atPDCD1 programmed cell death 10.0277-0.2149
2067_f_atBAX BCL2-associated X protein0.027-0.2089
34054_atTNFSF7 tumor necrosis factor (ligand) superfamily, member 70.0269-0.2088
32467_atSEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A-0.02690.2082
1860_atTP53BP2 tumor protein p53 binding protein, 2-0.02650.2052
37057_s_atTRAF3 TNF receptor-associated factor 30.0262-0.2034
34767_atMOAP1 modulator of apoptosis 1-0.02610.2024
38977_atYARS tyrosyl-tRNA synthetase0.0257-0.1995
31540_atTNFRSF9 tumor necrosis factor receptor superfamily, member 90.0245-0.1899
1497_atLTBR lymphotoxin beta receptor (TNFR superfamily, member 3)0.0242-0.1872
37202_atF2 coagulation factor II (thrombin)0.0239-0.1853
34822_atTP53BP2 tumor protein p53 binding protein, 2-0.02190.1699
848_atTRAF1 TNF receptor-associated factor 10.0218-0.1691
1563_s_atTNFRSF1A tumor necrosis factor receptor superfamily, member 1A-0.02080.1611
37767_atHD huntingtin (Huntington disease)-0.02040.1577
1673_atNGFR nerve growth factor receptor (TNFR superfamily, member 16)-0.020.155
114_r_atMAPT microtubule-associated protein tau0.0198-0.1535
38921_atPDE1B phosphodiesterase 1B, calmodulin-dependent-0.01940.1503
38743_f_atRAF1 v-raf-1 murine leukemia viral oncogene homolog 1-0.0190.1475
1911_s_atGADD45A growth arrest and DNA-damage-inducible, alpha0.0185-0.143
37871_atIAPP islet amyloid polypeptide-0.01830.1419
1152_i_atCGB chorionic gonadotropin, beta polypeptide0.0178-0.1379
378_s_atGML GPI anchored molecule like protein-0.01770.1371
39845_atPRSS25 protease, serine, 250.0172-0.1331
36183_atFASTK FAST kinase0.0171-0.1327
41724_atBCAP31 B-cell receptor-associated protein 310.017-0.1317
32114_s_atADORA2A adenosine A2a receptor-0.0170.1317
1359_atIL17 interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)-0.01640.1273
2028_s_atE2F1 E2F transcription factor 10.0163-0.1266
31611_s_atBCL2L11 BCL2-like 11 (apoptosis facilitator)0.0158-0.1221
33535_atP2RX1 purinergic receptor P2X, ligand-gated ion channel, 1-0.0150.1159
32004_s_atCDC2L1 cell division cycle 2-like 1 (PITSLRE proteins)0.0149-0.1152
40757_atGZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)-0.01450.1127
32832_atMAEA macrophage erythroblast attacher0.0143-0.1108
33166_atTRADD TNFRSF1A-associated via death domain-0.01370.1063
41847_atIL24 interleukin 24-0.01330.1033
40516_atAHR aryl hydrocarbon receptor-0.0130.1005
1008_f_atPRKR protein kinase, interferon-inducible double stranded RNA dependent-0.0130.1004
38413_atDAD1 defender against cell death 1-0.01280.0989
33784_atTRAF2 TNF receptor-associated factor 20.0126-0.0973
649_s_atCXCR4 chemokine (C-X-C motif) receptor 4-0.01250.0966
38900_atPAX3 paired box gene 3 (Waardenburg syndrome 1)0.0123-0.0953
39424_atTNFRSF14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)-0.01210.0936
41339_atUBE4B ubiquitination factor E4B (UFD2 homolog, yeast)-0.0120.0931
33398_atACINUS apoptotic chromatin condensation inducer in the nucleus0.0109-0.0848
32047_atDFFA DNA fragmentation factor, 45kDa, alpha polypeptide0.0108-0.0838
38823_s_atSTK17A serine/threonine kinase 17a (apoptosis-inducing)0.0108-0.0834
1345_s_atPAX3 paired box gene 3 (Waardenburg syndrome 1)0.0107-0.0826
32045_atDATF1 death associated transcription factor 1-0.01060.0822
33047_atBCL2L11 BCL2-like 11 (apoptosis facilitator)0.0105-0.0814
41700_atF2R coagulation factor II (thrombin) receptor-0.01030.0801
331_atMAPT microtubule-associated protein tau0.0103-0.0799
1322_atE2F1 E2F transcription factor 10.0103-0.0796
41762_atTIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 10.0099-0.0767
35000_atTNFSF9 tumor necrosis factor (ligand) superfamily, member 90.0097-0.075
475_atRIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1-0.00930.0718
35291_atBAG2 BCL2-associated athanogene 2-0.0090.0699
849_g_atTRAF1 TNF receptor-associated factor 10.0089-0.0689
38283_atEBAG9 estrogen receptor binding site associated, antigen, 90.0088-0.068
40680_atSPIN2 spindlin family, member 20.0086-0.0668
41419_atGULP1 GULP, engulfment adaptor PTB domain containing 10.0085-0.0661
40620_atPAWR PRKC, apoptosis, WT1, regulator0.0085-0.0657
36148_atAPLP1 amyloid beta (A4) precursor-like protein 10.0084-0.0648
38822_atSTK17A serine/threonine kinase 17a (apoptosis-inducing)0.0082-0.0637
33903_atDAPK3 death-associated protein kinase 3-0.00790.0612
2009_atPTK2B PTK2B protein tyrosine kinase 2 beta-0.00770.0597
1939_atTP53 tumor protein p53 (Li-Fraumeni syndrome)0.0066-0.0509
1153_f_atCGB chorionic gonadotropin, beta polypeptide0.0065-0.0502
1122_f_atCGB7 chorionic gonadotropin, beta polypeptide 70.0063-0.0488
2065_s_atBAX BCL2-associated X protein0.0062-0.0481
2066_atBAX BCL2-associated X protein-0.00610.047
1702_atIL2RA interleukin 2 receptor, alpha0.0058-0.0453
41560_atPDCD2 programmed cell death 2-0.00580.0448
35478_atLTBR lymphotoxin beta receptor (TNFR superfamily, member 3)0.0058-0.0447
34397_atOA48-18 acid-inducible phosphoprotein0.0053-0.041
40532_atBIRC5 baculoviral IAP repeat-containing 5 (survivin)0.0053-0.0409
36541_atDNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3-0.00520.0403
35150_atTNFRSF5 tumor necrosis factor receptor superfamily, member 5-0.00450.0347
855_atPDCD2 programmed cell death 20.0045-0.0346
294_s_atCDC2L1 cell division cycle 2-like 1 (PITSLRE proteins)0.0042-0.0326
37524_atSTK17B serine/threonine kinase 17b (apoptosis-inducing)-0.0030.023
113_i_atMAPT microtubule-associated protein tau-0.00280.0213
37226_atBNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1-0.00260.0205
1344_atPAX3 paired box gene 3 (Waardenburg syndrome 1)0.0015-0.0116
35875_atSGPL1 sphingosine-1-phosphate lyase 1-0.00120.0089
1746_s_atTRAF2 TNF receptor-associated factor 20.001-0.0077
35537_atTNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain-8e-040.0061
1858_atTNFSF6 tumor necrosis factor (ligand) superfamily, member 6-5e-040.0038
1851_s_atTNFSF6 tumor necrosis factor (ligand) superfamily, member 6-4e-040.0034
38405_atFXR1 fragile X mental retardation, autosomal homolog 1-4e-040.003

Performance on training data

 SensitivitySpecificity
ADENO0.978491
NORMAL10.97849

Performance on test data

 SensitivitySpecificity
ADENO0.934781
NORMAL10.93478

Predictions

 ClassADENONORMALPredictionn
CL2001031608AAADENO0.479890.52011 NORMAL
CL2001031611AA (testset)ADENO10 ADENO
CL2001031612AAADENO10 ADENO
CL2001031613AAADENO0.999955e-05 ADENO
CL2001031615AAADENO10 ADENO
CL2001031616AAADENO10 ADENO
CL2001031618AA (testset)ADENO10 ADENO
CL2001031622AAADENO10 ADENO
CL2001031625AA (testset)ADENO10 ADENO
CL2001031627AAADENO10 ADENO
CL2001031628AAADENO10 ADENO
CL2001031629AAADENO10 ADENO
CL2001031630AAADENO10 ADENO
CL2001031631AAADENO10 ADENO
CL2001031632AAADENO10 ADENO
CL2001031634AAADENO10 ADENO
CL2001031635AAADENO0.999820.00018 ADENO
CL2001031636AAADENO10 ADENO
CL2001032002AAADENO10 ADENO
CL2001032005AAADENO10 ADENO
CL2001032008AAADENO10 ADENO
CL2001032009AA (testset)ADENO10 ADENO
CL2001032011AAADENO0.99955e-04 ADENO
CL2001032012AA (testset)ADENO0.999890.00011 ADENO
CL2001032013AA (testset)ADENO0.999937e-05 ADENO
CL2001032015AAADENO0.999880.00012 ADENO
CL2001032016AAADENO10 ADENO
CL2001032019AAADENO10 ADENO
CL2001032020AAADENO10 ADENO
CL2001032025AAADENO10 ADENO
CL2001032026AAADENO10 ADENO
CL2001032027AA (testset)ADENO10 ADENO
CL2001032030AA (testset)ADENO10 ADENO
CL2001032031AAADENO10 ADENO
CL2001032032AA (testset)ADENO0.99991e-04 ADENO
CL2001032034AA (testset)ADENO0.439860.56014 NORMAL
CL2001032036AAADENO10 ADENO
CL2001032103AAADENO0.999991e-05 ADENO
CL2001032104AA (testset)ADENO10 ADENO
CL2001032105AAADENO10 ADENO
CL2001032107AAADENO10 ADENO
CL2001032108AA (testset)ADENO10 ADENO
CL2001032109AAADENO0.996690.00331 ADENO
CL2001032110AAADENO0.999955e-05 ADENO
CL2001032111AAADENO0.999540.00046 ADENO
CL2001032113AAADENO10 ADENO
CL2001032114AAADENO10 ADENO
CL2001032115AA (testset)ADENO10 ADENO
CL2001032116AA (testset)ADENO10 ADENO
CL2001032117AAADENO10 ADENO
CL2001032125AA (testset)ADENO10 ADENO
CL2001032130AAADENO10 ADENO
CL2001032132AAADENO10 ADENO
CL2001032134AA (testset)ADENO10 ADENO
CL2001032135AAADENO10 ADENO
CL2001032136AAADENO10 ADENO
CL2001032138AAADENO10 ADENO
CL2001032141AAADENO10 ADENO
CL2001032142AAADENO10 ADENO
CL2001032149AA (testset)ADENO10 ADENO
CL2001032155AA (testset)ADENO0.000270.99973 NORMAL
CL2001032156AAADENO0.995590.00441 ADENO
CL2001032211AA (testset)ADENO10 ADENO
CL2001032212AAADENO10 ADENO
CL2001032213AAADENO0.999540.00046 ADENO
CL2001032214AAADENO0.999660.00034 ADENO
CL2001032229AAADENO10 ADENO
CL2001032232AA (testset)ADENO10 ADENO
CL2001032233AAADENO10 ADENO
CL2001032241AAADENO0.999991e-05 ADENO
CL2001032242AAADENO10 ADENO
CL2001032243AAADENO10 ADENO
CL2001032248AAADENO10 ADENO
CL2001032249AA (testset)ADENO10 ADENO
CL2001032252AAADENO10 ADENO
CL2001032254AAADENO10 ADENO
CL2001032255AAADENO10 ADENO
CL2001032259AAADENO10 ADENO
CL2001032301AA (testset)ADENO0.999991e-05 ADENO
CL2001032306AAADENO10 ADENO
CL2001032307AAADENO0.994330.00567 ADENO
CL2001032308AA (testset)ADENO10 ADENO
CL2001032309AAADENO10 ADENO
CL2001032310AA (testset)ADENO10 ADENO
CL2001032311AAADENO10 ADENO
CL2001032312AAADENO10 ADENO
CL2001032313AA (testset)ADENO10 ADENO
CL2001032314AA (testset)ADENO10 ADENO
CL2001032316AAADENO10 ADENO
CL2001032601AA (testset)ADENO10 ADENO
CL2001032602AA (testset)ADENO10 ADENO
CL2001032604AAADENO10 ADENO
CL2001032610AAADENO10 ADENO
CL2001032612AAADENO10 ADENO
CL2001032613AAADENO10 ADENO
CL2001032614AAADENO10 ADENO
CL2001032616AA (testset)ADENO10 ADENO
CL2001032617AA (testset)ADENO10 ADENO
CL2001032620AAADENO10 ADENO
CL2001032625AAADENO10 ADENO
CL2001032628AAADENO10 ADENO
CL2001032638AA (testset)ADENO10 ADENO
CL2001032640AAADENO10 ADENO
CL2001032643AA (testset)ADENO10 ADENO
CL2001032647AAADENO0.999330.00067 ADENO
CL2001032701AA (testset)ADENO10 ADENO
CL2001032702AAADENO10 ADENO
CL2001032703AA (testset)ADENO10 ADENO
CL2001032704AA (testset)ADENO10 ADENO
CL2001032706AAADENO10 ADENO
CL2001032709AAADENO10 ADENO
CL2001032716AAADENO10 ADENO
CL2001032717AAADENO10 ADENO
CL2001032729AAADENO10 ADENO
CL2001032730AAADENO10 ADENO
CL2001032733AA (testset)ADENO10 ADENO
CL2001032738AA (testset)ADENO10 ADENO
CL2001032742AAADENO10 ADENO
CL2001032746AAADENO10 ADENO
CL2001032747AAADENO10 ADENO
CL2001032833AA (testset)ADENO10 ADENO
CL2001032836AAADENO10 ADENO
CL2001032838AAADENO10 ADENO
CL2001032839AAADENO10 ADENO
CL2001032841AA (testset)ADENO10 ADENO
CL2001032842AAADENO10 ADENO
CL2001032843AA (testset)ADENO10 ADENO
CL2001032845AA (testset)ADENO0.999991e-05 ADENO
CL2001032846AAADENO10 ADENO
CL2001032848AA (testset)ADENO01 NORMAL
CL2001032856AAADENO10 ADENO
CL2001032857AAADENO10 ADENO
CL2001040305AA (testset)ADENO10 ADENO
CL2001040306AA (testset)ADENO10 ADENO
CL2001041708AA (testset)ADENO10 ADENO
CL2001041711AAADENO10 ADENO
CL2001041716AAADENO0.96540.0346 ADENO
CL2001042505AA (testset)ADENO10 ADENO
CL2001042506AAADENO0.004560.99544 NORMAL
CL2001032010AA (testset)NORMAL8e-050.99992 NORMAL
CL2001032041AANORMAL01 NORMAL
CL2001032043AA (testset)NORMAL01 NORMAL
CL2001032045AANORMAL01 NORMAL
CL2001032046AANORMAL01 NORMAL
CL2001032102AANORMAL01 NORMAL
CL2001032128AA (testset)NORMAL01 NORMAL
CL2001032147AANORMAL01 NORMAL
CL2001032202AANORMAL01 NORMAL
CL2001032206AA (testset)NORMAL01 NORMAL
CL2001032220AANORMAL01 NORMAL
CL2001032256AANORMAL0.000190.99981 NORMAL
CL2001032304AANORMAL0.010420.98958 NORMAL
CL2001032718AANORMAL01 NORMAL
CL2001032724AANORMAL9e-050.99991 NORMAL
CL2001032725AA (testset)NORMAL01 NORMAL
CL2001032727AANORMAL01 NORMAL

 


Generated by StAM on Tue Sep 7 17:18:45 2004