GO:0006886


GO:0006886

intracellular protein transport
(annotated genes)

Biological
Process

Parent node

This leaf node contains 212 genes

The following 169 of these are used in classification:

 SymbolGenenameADENO scoreNORMAL score
41549_s_atAP1S2 adaptor-related protein complex 1, sigma 2 subunit-0.1351.0459
39857_atSTX11 syntaxin 11-0.13311.0314
38635_atSSR4 signal sequence receptor, delta (translocon-associated protein delta)0.1305-1.0116
38164_atRPGR retinitis pigmentosa GTPase regulator-0.11810.9153
35325_atRAB14 RAB14, member RAS oncogene family-0.10180.7892
36660_atRAB11A RAB11A, member RAS oncogene family-0.08390.6503
33802_atTOM1 target of myb1 (chicken)-0.08280.6415
39858_s_atSTX11 syntaxin 11-0.0810.6275
41462_atSNX2 sorting nexin 2-0.08050.6242
38774_atSTX7 syntaxin 7-0.0790.6124
40278_atGGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 2-0.07890.6113
40407_atKPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.0763-0.5914
33402_atKDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 30.0684-0.5303
41163_atP24B integral type I protein0.0663-0.5139
36972_atRNP24 coated vesicle membrane protein0.0652-0.5055
35304_atRAB6A RAB6A, member RAS oncogene family-0.06350.4923
39214_atSSR4 signal sequence receptor, delta (translocon-associated protein delta)0.0627-0.486
39360_atSNX3 sorting nexin 3-0.06250.4842
41864_atEPIM epimorphin-0.06170.4783
38798_s_atAP1G2 adaptor-related protein complex 1, gamma 2 subunit0.0615-0.477
35340_atRAB8A RAB8A, member RAS oncogene family-0.05940.4602
40229_atTOM1L1 target of myb1-like 1 (chicken)0.0565-0.4379
1074_atRAB1A RAB1A, member RAS oncogene family0.0547-0.424
36128_atTMP21 transmembrane trafficking protein0.0545-0.4221
1840_g_atRAN RAN, member RAS oncogene family0.0544-0.4219
37184_atSTX1A syntaxin 1A (brain)0.0539-0.4175
36977_atNAPA N-ethylmaleimide-sensitive factor attachment protein, alpha-0.05340.4139
37654_atSNX17 sorting nexin 17-0.05240.4063
33942_s_atSTXBP1 syntaxin binding protein 1-0.04810.3729
38708_atRAN RAN, member RAS oncogene family0.0475-0.3682
40926_atBCAP31 B-cell receptor-associated protein 310.0461-0.357
32219_atTLK1 tousled-like kinase 10.0455-0.3527
35166_atDSCR3 Down syndrome critical region gene 3-0.04350.3372
1839_atRAN RAN, member RAS oncogene family0.0428-0.3316
33349_atTNPO1 transportin 1-0.04130.3204
33877_s_atEXOC7 exocyst complex component 70.0395-0.3063
38719_atNSF N-ethylmaleimide-sensitive factor0.0394-0.3057
32523_atCLTB clathrin, light polypeptide (Lcb)-0.0380.2942
39272_g_atRAB4B RAB4B, member RAS oncogene family-0.03780.2929
34199_atSEC24A SEC24 related gene family, member A (S. cerevisiae)0.0375-0.2907
31662_atVPS45A vacuolar protein sorting 45A (yeast)0.0373-0.289
38799_atAP1G2 adaptor-related protein complex 1, gamma 2 subunit0.0371-0.2871
41548_atAP1S2 adaptor-related protein complex 1, sigma 2 subunit-0.03680.2849
33434_atBET1 BET1 homolog (S. cerevisiae)0.0366-0.2838
34326_atCOPB coatomer protein complex, subunit beta0.0356-0.276
39490_f_atARFGAP3 ADP-ribosylation factor GTPase activating protein 30.0337-0.2612
31654_atSORCS3 VPS10 domain receptor protein SORCS 3-0.03330.2582
35297_atGGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 20.0333-0.2581
37386_i_atKDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 10.0333-0.2578
38471_r_atAPPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2-0.03250.252
39523_atSTX16 syntaxin 160.0323-0.2504
32290_atSCAMP1 secretory carrier membrane protein 1-0.0320.2479
33887_atHGS hepatocyte growth factor-regulated tyrosine kinase substrate0.0311-0.2408
38259_atSTXBP2 syntaxin binding protein 2-0.03010.2334
35620_atTOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)0.03-0.2327
39025_atTOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast)-0.02940.2279
34895_atSEC23IP SEC23 interacting protein0.0292-0.2265
32522_f_atCLTB clathrin, light polypeptide (Lcb)-0.02920.2263
41121_atSTX16 syntaxin 160.0292-0.2261
38718_atCOG4 component of oligomeric golgi complex 40.0289-0.2242
34393_r_atRAB1A RAB1A, member RAS oncogene family0.0289-0.2237
40885_s_atSTX16 syntaxin 160.0287-0.2224
35754_atTMP21 transmembrane trafficking protein-0.02850.2212
39795_atAP2M1 adaptor-related protein complex 2, mu 1 subunit-0.02840.2205
38804_atCSE1L CSE1 chromosome segregation 1-like (yeast)0.0274-0.2126
32770_atSEC24D SEC24 related gene family, member D (S. cerevisiae)0.0272-0.2111
41251_atTRIP3 thyroid hormone receptor interactor 30.026-0.2014
35790_atVPS26 vacuolar protein sorting 26 (yeast)-0.02540.1972
38525_atSTAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 20.024-0.1861
32487_s_atKPNA4 karyopherin alpha 4 (importin alpha 3)0.024-0.1861
34392_s_atRAB1A RAB1A, member RAS oncogene family0.0239-0.1849
40289_atNAPG N-ethylmaleimide-sensitive factor attachment protein, gamma0.0236-0.1833
36955_atLMAN2 lectin, mannose-binding 20.0236-0.1827
41451_s_atSARA1 SAR1a gene homolog 1 (S. cerevisiae)0.0234-0.1816
32799_atSCAMP3 secretory carrier membrane protein 30.023-0.1781
623_s_atRAB2 RAB2, member RAS oncogene family0.0228-0.1768
34052_atEPIM epimorphin-0.02230.1728
39905_i_atARFGAP3 ADP-ribosylation factor GTPase activating protein 30.0223-0.1727
37962_r_atSTXBP3 syntaxin binding protein 3-0.02180.1688
31858_atNUTF2 nuclear transport factor 20.0216-0.1677
39099_atSEC23A Sec23 homolog A (S. cerevisiae)0.0216-0.1671
37973_atSNX13 sorting nexin 130.02-0.1548
38470_i_atAPPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2-0.01990.1545
38911_atNUP98 nucleoporin 98kDa-0.01990.1541
36110_atRAB5A RAB5A, member RAS oncogene family-0.01940.1504
39130_atVPS39 vacuolar protein sorting 39 (yeast)-0.01930.1495
37387_r_atKDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 10.0193-0.1493
33422_atSEC13L1 SEC13-like 1 (S. cerevisiae)0.0183-0.1415
38264_atRABIF RAB interacting factor0.018-0.1399
35845_atSEC24B SEC24 related gene family, member B (S. cerevisiae)-0.0170.1318
34836_atRAB5C RAB5C, member RAS oncogene family-0.01660.1288
37959_atGGA3 golgi associated, gamma adaptin ear containing, ARF binding protein 3-0.01650.1277
620_atRAB3A RAB3A, member RAS oncogene family0.0165-0.1277
37464_atPEX13 peroxisome biogenesis factor 130.0163-0.1266
624_atRAB3B RAB3B, member RAS oncogene family0.0163-0.1263
35446_atSNX26 sorting nexin 260.016-0.124
35886_atPACSIN2 protein kinase C and casein kinase substrate in neurons 20.016-0.1236
39457_r_atSNX4 sorting nexin 4-0.01570.1219
35642_atMTX2 metaxin 20.0153-0.1188
33423_g_atSEC13L1 SEC13-like 1 (S. cerevisiae)0.015-0.1159
39307_s_atCLTB clathrin, light polypeptide (Lcb)-0.01490.1156
36049_atRAB6B RAB6B, member RAS oncogene family0.0149-0.1151
37911_atSTX4A syntaxin 4A (placental)-0.01460.1129
39446_s_atKPNA6 karyopherin alpha 6 (importin alpha 7)-0.01430.1111
34478_atRAB11B RAB11B, member RAS oncogene family0.0139-0.1079
35994_atSNX26 sorting nexin 26-0.01390.1073
33435_r_atBET1 BET1 homolog (S. cerevisiae)0.0134-0.1037
34753_atSYBL1 synaptobrevin-like 1-0.01290.1002
41724_atBCAP31 B-cell receptor-associated protein 310.0127-0.0984
40824_atXPO7 exportin 7-0.01240.0957
40275_atKPNA6 karyopherin alpha 6 (importin alpha 7)-0.01230.0955
37597_s_atSEC6L1 SEC6-like 1 (S. cerevisiae)0.0122-0.0947
39538_atSORT1 sortilin 1-0.01190.0925
39934_atRAB36 RAB36, member RAS oncogene family-0.01160.0896
34159_atRAB7 RAB7, member RAS oncogene family0.0115-0.0888
34737_atCOG5 component of oligomeric golgi complex 50.0111-0.0863
36498_atAP1S1 adaptor-related protein complex 1, sigma 1 subunit0.011-0.0854
38849_atSCAMP1 secretory carrier membrane protein 1-0.0110.085
36962_atCOPA coatomer protein complex, subunit alpha0.0109-0.0845
32178_r_atSNAP23 synaptosomal-associated protein, 23kDa-0.01090.0843
35443_atKPNA6 karyopherin alpha 6 (importin alpha 7)0.01-0.0778
32581_atRAB2 RAB2, member RAS oncogene family-0.010.0774
600_atRAB5A RAB5A, member RAS oncogene family0.01-0.0772
37466_atRAB7L1 RAB7, member RAS oncogene family-like 1-0.00950.0734
32030_atAP3S2 adaptor-related protein complex 3, sigma 2 subunit0.0093-0.0724
40725_atGOSR1 golgi SNAP receptor complex member 10.0086-0.0669
39308_r_atCLTB clathrin, light polypeptide (Lcb)-0.00860.0666
35445_atSNX26 sorting nexin 260.0086-0.0663
33603_atSSR4 signal sequence receptor, delta (translocon-associated protein delta)0.0084-0.0649
31578_atXPO4 exportin 4-0.00830.0643
39988_atTAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.0081-0.063
33335_atCOG7 component of oligomeric golgi complex 7-0.00810.0629
38647_atCOPE coatomer protein complex, subunit epsilon0.0079-0.0612
35779_atVPS45A vacuolar protein sorting 45A (yeast)0.0079-0.061
40277_atGGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 2-0.00760.0592
980_atNPC1 Niemann-Pick disease, type C1-0.00750.0579
31989_s_atKIF17 kinesin family member 17-0.00720.056
32823_atVPS11 vacuolar protein sorting 11 (yeast)-0.00680.0525
41001_atRPH3A rabphilin 3A homolog (mouse)-0.00670.0518
38074_atAP3S1 adaptor-related protein complex 3, sigma 1 subunit0.0064-0.0495
40463_atTNPO1 transportin 10.0057-0.0439
40883_atSTX16 syntaxin 160.0055-0.0426
37047_atNPC1 Niemann-Pick disease, type C1-0.00540.0422
39975_atGGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 20.0051-0.0392
36461_atIL1RL1LG interleukin 1 receptor-like 1 ligand0.0049-0.0377
37045_atSNX19 sorting nexin 19-0.00480.0372
40605_atSNX4 sorting nexin 4-0.00480.0369
38390_atCOG2 component of oligomeric golgi complex 20.0045-0.0346
160_atSTAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1-0.00430.0335
40851_r_atSEC23B Sec23 homolog B (S. cerevisiae)0.0043-0.0331
35383_atNBR2 neighbor of BRCA1 gene 20.0042-0.0327
39590_atAPBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)0.0042-0.0322
32763_r_atRAB3-GAP150 rab3 GTPase-activating protein, non-catalytic subunit (150kD)0.004-0.0313
32762_i_atRAB3-GAP150 rab3 GTPase-activating protein, non-catalytic subunit (150kD)0.0037-0.0289
33717_atRAB22A RAB22A, member RAS oncogene family0.0035-0.0272
39080_atKDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 20.0029-0.0226
41450_atSARA1 SAR1a gene homolog 1 (S. cerevisiae)0.0029-0.0225
35725_atKPNA3 karyopherin alpha 3 (importin alpha 4)-0.00280.0214
32179_s_atSNAP23 synaptosomal-associated protein, 23kDa-0.00250.0197
37808_atSNX7 sorting nexin 70.0024-0.019
622_atRAB6A RAB6A, member RAS oncogene family0.0024-0.0185
33732_atAP4M1 adaptor-related protein complex 4, mu 1 subunit0.0024-0.0184
40745_atAP1B1 adaptor-related protein complex 1, beta 1 subunit-0.00220.0167
36704_atAP4S1 adaptor-related protein complex 4, sigma 1 subunit-0.00150.0118
39906_r_atARFGAP3 ADP-ribosylation factor GTPase activating protein 3-0.00110.0087
38937_atAP3B2 adaptor-related protein complex 3, beta 2 subunit0.0011-0.0086
39859_r_atSTX11 syntaxin 110.0011-0.0084
36945_atC12orf8 chromosome 12 open reading frame 87e-04-0.0057
40152_r_atPXR1 peroxisome receptor 12e-04-0.0019

Performance on training data

 SensitivitySpecificity
ADENO10.91667
NORMAL0.916671

Performance on test data

 SensitivitySpecificity
ADENO0.934781
NORMAL10.93478

Predictions

 ClassADENONORMALPredictionn
CL2001031608AAADENO0.993940.00606 ADENO
CL2001031611AA (testset)ADENO0.999991e-05 ADENO
CL2001031612AAADENO0.999240.00076 ADENO
CL2001031613AAADENO0.976020.02398 ADENO
CL2001031615AAADENO0.999520.00048 ADENO
CL2001031616AAADENO0.999991e-05 ADENO
CL2001031618AA (testset)ADENO0.997660.00234 ADENO
CL2001031622AAADENO10 ADENO
CL2001031625AA (testset)ADENO10 ADENO
CL2001031627AAADENO0.999991e-05 ADENO
CL2001031628AAADENO10 ADENO
CL2001031629AAADENO10 ADENO
CL2001031630AAADENO0.999991e-05 ADENO
CL2001031631AAADENO10 ADENO
CL2001031632AAADENO0.999991e-05 ADENO
CL2001031634AAADENO10 ADENO
CL2001031635AAADENO10 ADENO
CL2001031636AAADENO0.999982e-05 ADENO
CL2001032002AAADENO0.999991e-05 ADENO
CL2001032005AAADENO10 ADENO
CL2001032008AAADENO10 ADENO
CL2001032009AA (testset)ADENO10 ADENO
CL2001032011AAADENO0.996530.00347 ADENO
CL2001032012AA (testset)ADENO0.636710.36329 ADENO
CL2001032013AA (testset)ADENO0.998270.00173 ADENO
CL2001032015AAADENO0.996980.00302 ADENO
CL2001032016AAADENO10 ADENO
CL2001032019AAADENO10 ADENO
CL2001032020AAADENO10 ADENO
CL2001032025AAADENO0.999230.00077 ADENO
CL2001032026AAADENO0.999890.00011 ADENO
CL2001032027AA (testset)ADENO0.999730.00027 ADENO
CL2001032030AA (testset)ADENO10 ADENO
CL2001032031AAADENO0.999630.00037 ADENO
CL2001032032AA (testset)ADENO0.9880.012 ADENO
CL2001032034AA (testset)ADENO0.336430.66357 NORMAL
CL2001032036AAADENO0.995970.00403 ADENO
CL2001032103AAADENO0.988980.01102 ADENO
CL2001032104AA (testset)ADENO0.999982e-05 ADENO
CL2001032105AAADENO10 ADENO
CL2001032107AAADENO10 ADENO
CL2001032108AA (testset)ADENO0.998720.00128 ADENO
CL2001032109AAADENO0.939420.06058 ADENO
CL2001032110AAADENO0.999580.00042 ADENO
CL2001032111AAADENO0.999982e-05 ADENO
CL2001032113AAADENO10 ADENO
CL2001032114AAADENO0.999570.00043 ADENO
CL2001032115AA (testset)ADENO0.999991e-05 ADENO
CL2001032116AA (testset)ADENO0.999991e-05 ADENO
CL2001032117AAADENO10 ADENO
CL2001032125AA (testset)ADENO10 ADENO
CL2001032130AAADENO10 ADENO
CL2001032132AAADENO10 ADENO
CL2001032134AA (testset)ADENO0.999470.00053 ADENO
CL2001032135AAADENO0.999955e-05 ADENO
CL2001032136AAADENO0.999946e-05 ADENO
CL2001032138AAADENO0.999991e-05 ADENO
CL2001032141AAADENO10 ADENO
CL2001032142AAADENO0.999640.00036 ADENO
CL2001032149AA (testset)ADENO0.998990.00101 ADENO
CL2001032155AA (testset)ADENO0.021430.97857 NORMAL
CL2001032156AAADENO0.999420.00058 ADENO
CL2001032211AA (testset)ADENO10 ADENO
CL2001032212AAADENO10 ADENO
CL2001032213AAADENO0.994250.00575 ADENO
CL2001032214AAADENO0.997470.00253 ADENO
CL2001032229AAADENO0.999973e-05 ADENO
CL2001032232AA (testset)ADENO10 ADENO
CL2001032233AAADENO10 ADENO
CL2001032241AAADENO0.999982e-05 ADENO
CL2001032242AAADENO10 ADENO
CL2001032243AAADENO10 ADENO
CL2001032248AAADENO10 ADENO
CL2001032249AA (testset)ADENO10 ADENO
CL2001032252AAADENO10 ADENO
CL2001032254AAADENO10 ADENO
CL2001032255AAADENO10 ADENO
CL2001032259AAADENO0.995110.00489 ADENO
CL2001032301AA (testset)ADENO0.999946e-05 ADENO
CL2001032306AAADENO0.999955e-05 ADENO
CL2001032307AAADENO0.784980.21502 ADENO
CL2001032308AA (testset)ADENO10 ADENO
CL2001032309AAADENO0.997690.00231 ADENO
CL2001032310AA (testset)ADENO0.999780.00022 ADENO
CL2001032311AAADENO10 ADENO
CL2001032312AAADENO10 ADENO
CL2001032313AA (testset)ADENO10 ADENO
CL2001032314AA (testset)ADENO0.999991e-05 ADENO
CL2001032316AAADENO0.999991e-05 ADENO
CL2001032601AA (testset)ADENO0.999991e-05 ADENO
CL2001032602AA (testset)ADENO10 ADENO
CL2001032604AAADENO10 ADENO
CL2001032610AAADENO0.99690.0031 ADENO
CL2001032612AAADENO0.998840.00116 ADENO
CL2001032613AAADENO10 ADENO
CL2001032614AAADENO10 ADENO
CL2001032616AA (testset)ADENO0.999310.00069 ADENO
CL2001032617AA (testset)ADENO10 ADENO
CL2001032620AAADENO0.999982e-05 ADENO
CL2001032625AAADENO10 ADENO
CL2001032628AAADENO0.999973e-05 ADENO
CL2001032638AA (testset)ADENO0.99991e-04 ADENO
CL2001032640AAADENO10 ADENO
CL2001032643AA (testset)ADENO10 ADENO
CL2001032647AAADENO0.994010.00599 ADENO
CL2001032701AA (testset)ADENO10 ADENO
CL2001032702AAADENO10 ADENO
CL2001032703AA (testset)ADENO10 ADENO
CL2001032704AA (testset)ADENO10 ADENO
CL2001032706AAADENO10 ADENO
CL2001032709AAADENO10 ADENO
CL2001032716AAADENO10 ADENO
CL2001032717AAADENO0.999928e-05 ADENO
CL2001032729AAADENO0.999964e-05 ADENO
CL2001032730AAADENO10 ADENO
CL2001032733AA (testset)ADENO10 ADENO
CL2001032738AA (testset)ADENO10 ADENO
CL2001032742AAADENO0.999991e-05 ADENO
CL2001032746AAADENO10 ADENO
CL2001032747AAADENO10 ADENO
CL2001032833AA (testset)ADENO0.996820.00318 ADENO
CL2001032836AAADENO10 ADENO
CL2001032838AAADENO10 ADENO
CL2001032839AAADENO0.999991e-05 ADENO
CL2001032841AA (testset)ADENO10 ADENO
CL2001032842AAADENO10 ADENO
CL2001032843AA (testset)ADENO10 ADENO
CL2001032845AA (testset)ADENO0.999946e-05 ADENO
CL2001032846AAADENO10 ADENO
CL2001032848AA (testset)ADENO8e-050.99992 NORMAL
CL2001032856AAADENO0.999991e-05 ADENO
CL2001032857AAADENO0.999550.00045 ADENO
CL2001040305AA (testset)ADENO10 ADENO
CL2001040306AA (testset)ADENO10 ADENO
CL2001041708AA (testset)ADENO10 ADENO
CL2001041711AAADENO0.99240.0076 ADENO
CL2001041716AAADENO0.999510.00049 ADENO
CL2001042505AA (testset)ADENO0.99982e-04 ADENO
CL2001042506AAADENO0.983720.01628 ADENO
CL2001032010AA (testset)NORMAL0.001110.99889 NORMAL
CL2001032041AANORMAL4e-050.99996 NORMAL
CL2001032043AA (testset)NORMAL2e-050.99998 NORMAL
CL2001032045AANORMAL01 NORMAL
CL2001032046AANORMAL01 NORMAL
CL2001032102AANORMAL2e-050.99998 NORMAL
CL2001032128AA (testset)NORMAL0.000390.99961 NORMAL
CL2001032147AANORMAL01 NORMAL
CL2001032202AANORMAL01 NORMAL
CL2001032206AA (testset)NORMAL0.000190.99981 NORMAL
CL2001032220AANORMAL01 NORMAL
CL2001032256AANORMAL0.947060.05294 ADENO
CL2001032304AANORMAL0.008510.99149 NORMAL
CL2001032718AANORMAL01 NORMAL
CL2001032724AANORMAL0.00130.9987 NORMAL
CL2001032725AA (testset)NORMAL2e-050.99998 NORMAL
CL2001032727AANORMAL01 NORMAL

 


Generated by StAM on Tue Sep 7 17:18:40 2004