Package: twilight
Description: In a typical microarray setting with gene expression data
observed under two conditions, the local false discovery rate
describes the probability that a gene is not differentially
expressed between the two conditions given its corrresponding
observed score or p-value level. The resulting curve of
p-values versus local false discovery rate offers an insight
into the twilight zone between clear differential and clear
non-differential gene expression. Package TWILIGHT contains two
main functions: Function twilight.pval performs a two-condition
test on differences in means for a given input matrix or
expression set and computes permutation based p-values.
Function twilight performs a stochastic downhill search to
estimate local false discovery rates and effect size
distributions.
Version: 1.9.2
Author: Stefanie Scheid
Maintainer: Stefanie Scheid
Dependencies: R (>= 2.1.0), splines (>= 2.2.0), stats (>= 2.2.0)
Suggests: golubEsets (>= 1.2.3), vsn (>= 1.7.2)
SystemRequirements: None
License: GPL version 2.0 or newer
URL: http://compdiag.molgen.mpg.de/software/twilight.shtml
Source package download
Win32 package download